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Search term: YAL021C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CCR4
SGD link S000000019
Alternative ID YAL021C
Description Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening
Synonyms YAL021C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0620 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Glucose-repressible alcohol dehydrogenase transcriptional effector CCR4 and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g31500 GI:15222367
Arabidopsis thaliana (Ath) At1g31530 GI:15222370
Arabidopsis thaliana (Ath) At3g58560 GI:15231072
Arabidopsis thaliana (Ath) At3g58580 GI:15231075
Caenorhabditis elegans (Cel) CE16315
(WBGene00011268)		 GI:17554634 O18005
Caenorhabditis elegans (Cel) CE24708 GI:17544526
Caenorhabditis elegans (Cel) CE24709 GI:17544524
Drosophila melanogaster (Dme) 7299411 GI:7299411
Drosophila melanogaster (Dme) 7301122 GI:7301122
Drosophila melanogaster (Dme) 7301124 GI:7301124
Homo sapiens (Hsa) Hs14737177 GI:14737177
Homo sapiens (Hsa) Hs14785495 GI:14785495
Homo sapiens (Hsa) Hs20476839 GI:20476839
Homo sapiens (Hsa) Hs21687268 GI:16554263 Q96LI5
Homo sapiens (Hsa) Hs22050737 GI:22050737
Homo sapiens (Hsa) Hs6912294 GI:6912294
Saccharomyces cerevisiae (Sce) YAL021c
(S000000019)		 GI:6319298 P31384
Saccharomyces cerevisiae (Sce) YOL042w
(S000005402)		 GI:6324531 Q08213
Schizosaccharomyces pombe (Spo) SPCC31H12.08c GI:19075401 O74874
Encephalitozoon cuniculi (Ecu) ECU11g0770 GI:19074877 Q8SU52
Arabidopsis thaliana (Ath) At1g31500 GI:15222367
Arabidopsis thaliana (Ath) At1g31530 GI:15222370
Arabidopsis thaliana (Ath) At3g58560 GI:15231072
Arabidopsis thaliana (Ath) At3g58580 GI:15231075
Caenorhabditis elegans (Cel) CE16315
(WBGene00011268)		 GI:17554634 O18005
Caenorhabditis elegans (Cel) CE24708 GI:17544526
Caenorhabditis elegans (Cel) CE24709 GI:17544524
Drosophila melanogaster (Dme) 7299411 GI:7299411
Drosophila melanogaster (Dme) 7301122 GI:7301122
Drosophila melanogaster (Dme) 7301124 GI:7301124
Homo sapiens (Hsa) Hs14737177 GI:14737177
Homo sapiens (Hsa) Hs14785495 GI:14785495
Homo sapiens (Hsa) Hs20476839 GI:20476839
Homo sapiens (Hsa) Hs21687268 GI:16554263 Q96LI5
Homo sapiens (Hsa) Hs22050737 GI:22050737
Homo sapiens (Hsa) Hs6912294 GI:6912294
Saccharomyces cerevisiae (Sce) YAL021c
(S000000019)		 GI:6319298 P31384
Saccharomyces cerevisiae (Sce) YOL042w
(S000005402)		 GI:6324531 Q08213
Schizosaccharomyces pombe (Spo) SPCC31H12.08c GI:19075401 O74874
Encephalitozoon cuniculi (Ecu) ECU11g0770 GI:19074877 Q8SU52


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000000019
GO:0005575 cellular_component C
ND
AthAt1g31530
At1g31500
At3g58560
At3g58580
GO:0005634 nucleus C
IDA
SpoSPCC31H12.08c
GO:0005737 cytoplasm C
IDA
SceS000000019
GO:0005739 mitochondrion C
IDA
SceS000005402
GO:0005829 cytosol C
IDA
SpoSPCC31H12.08c
GO:0016593 Cdc73/Paf1 complex C
IPI
SceS000000019
GO:0030015 CCR4-NOT core complex C
IPI
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0004519 endonuclease activity F
ISS
SceS000005402
GO:0016787 hydrolase activity F
ISS
AthAt3g58560
At3g58580
At1g31500
At1g31530
GO:0000076 DNA replication checkpoint P
IGI
SceS000000019
GO:0000288 nuclear-transcribed mRNA catabolic process,
deadenylation-dependent decay		 P
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
GO:0000289 nuclear-transcribed mRNA poly(A) tail
shortening		 P
IDA
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0006260 DNA replication P
IGI
SceS000000019
GO:0006354 RNA elongation P
IC
SpoSPCC31H12.08c
RCA
SceS000000019
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IPI
SceS000000019
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IGI
SceS000000019
IMP
SceS000000019
GO:0006414 translational elongation P
RCA
SceS000005402
GO:0007089 traversing start control point of mitotic cell
cycle		 P
IMP
SceS000000019
GO:0008150 biological_process P
ND
AthAt3g58560
At1g31500
SceS000005402
GO:0048478 replication fork protection P
IGI
SceS000000019

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
100830

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CNOT6L GI:115583679
Pan troglodytes (Ptr) CNOT6L GI:114594078
Canis familiaris (Cfa) CNOT6L GI:74001681
Mus musculus (Mmu) Cnot6l
(MGI:2443154)		 GI:121674807 Q8VEG6
Rattus norvegicus (Rno) Cnot6l GI:109499497
Gallus gallus (Gga) CNOT6L GI:118089945
Schizosaccharomyces pombe (Spo) ccr4
(SPCC31H12.08c)		 GI:19075401 O74874
Saccharomyces cerevisiae (Sce) CCR4
(S000000019)		 GI:6319298 P31384
Kluyveromyces lactis (Kla) KLLA0F15884g GI:50311541
Eremothecium gossypii (Ego) AGOS_ACR288W GI:45185974
Magnaporthe grisea (Mgr) MGG_13020 GI:145615065
Neurospora crassa (Ncr) NCU07779.1 GI:32416014


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000000019
GO:0005575 cellular_component C
ND
MmuMGI:2443154
GO:0005634 nucleus C
IDA
SpoSPCC31H12.08c
GO:0005737 cytoplasm C
IDA
SceS000000019
GO:0005829 cytosol C
IDA
SpoSPCC31H12.08c
GO:0016593 Cdc73/Paf1 complex C
IPI
SceS000000019
GO:0030015 CCR4-NOT core complex C
IPI
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0005515 protein binding F
IPI
HsaCNOT6L
MmuMGI:2443154
GO:0000076 DNA replication checkpoint P
IGI
SceS000000019
GO:0000288 nuclear-transcribed mRNA catabolic process,
deadenylation-dependent decay		 P
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
GO:0000289 nuclear-transcribed mRNA poly(A) tail
shortening		 P
IDA
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0006260 DNA replication P
IGI
SceS000000019
GO:0006354 RNA elongation P
IC
SpoSPCC31H12.08c
RCA
SceS000000019
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IPI
SceS000000019
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IGI
SceS000000019
IMP
SceS000000019
GO:0007089 traversing start control point of mitotic cell
cycle		 P
IMP
SceS000000019
GO:0008150 biological_process P
ND
MmuMGI:2443154
GO:0048478 replication fork protection P
IGI
SceS000000019

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_632

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6948 ENSANGP00000023705
Ashbya gossypii (Ago) ago1335 ACR288W
Arabidopsis thaliana (Ath) ath17263 At3g58560.1
Arabidopsis thaliana (Ath) ath17265 At3g58580.1
Caenorhabditis elegans (Cel) cel21437 ZC518.3a
(CE31743;
WBGene00000376)
Caenorhabditis elegans (Cel) cel21438 ZC518.3b
(CE31744)
Caenorhabditis elegans (Cel) cel21439 ZC518.3c
(CE31745)
Candida glabrata (Cgl) cgl2329 CAGL0H06149g
Cryptococcus neoformans (Cne) cne4463 177.m03216
Dictyostelium discoideum (Ddi) ddi7452 DDB0188431
Debaryomyces hansenii (Dha) dha4591 DEHA0F04554g
Debaryomyces hansenii (Dha) dha4592 DEHA0F04576g
Drosophila melanogaster (Dme) dme14175 CG31137-PA
Drosophila melanogaster (Dme) dme14171 CG31137-PB
Drosophila melanogaster (Dme) dme14173 CG31137-PC
Drosophila melanogaster (Dme) dme14174 CG31137-PD
Drosophila melanogaster (Dme) dme14172 CG31137-PE
Drosophila melanogaster (Dme) dme14176 CG31137-PF
Danio rerio (Dre) dre19484 ENSDARP00000009646
Danio rerio (Dre) dre22942 ENSDARP00000015348
(cnot6)		 Q7ZU49
Danio rerio (Dre) dre5963 ENSDARP00000030084
(LOC560386)
Danio rerio (Dre) dre5965 ENSDARP00000031751
(LOC560386)
Danio rerio (Dre) dre5964 ENSDARP00000032276
Danio rerio (Dre) dre22941 ENSDARP00000032583
(cnot6)		 Q6PE30
Encephalitozoon cuniculi (Ecu) ecu965 19074877
Takifugu rubripes (Fru) fru10020 SINFRUP00000144958
Gallus gallus (Gga) gga5962 ENSGALP00000009685
(CNOT6)
Gallus gallus (Gga) gga5963 ENSGALP00000009686
Gallus gallus (Gga) gga17451 ENSGALP00000016801
(CNOT6L)
Homo sapiens (Hsa) hsa26316 ENSP00000261951
(CNOT6)		 Q9ULM6
Homo sapiens (Hsa) hsa24289 ENSP00000264903
(CNOT6L)		 Q96LI5-1
Kluyveromyces lactis (Kla) kla4795 KLLA0F15884g
Mus musculus (Mmu) mmu3556 ENSMUSP00000020624
(MGI:2144529)		 Q8K3P5-2
Mus musculus (Mmu) mmu20424 ENSMUSP00000047522
(MGI:2443154)		 Q8VEG6-2
Mus musculus (Mmu) mmu20423 ENSMUSP00000066519
Neurospora crassa (Ncr) ncr7575 NCU07779.2
Oryza sativa (Osa) osa16792 3141.m00168
Oryza sativa (Osa) osa17143 3153.m00132
Oryza sativa (Osa) osa17190 3153.m00189
Oryza sativa (Osa) osa70853 6988.m00146
Oryza sativa (Osa) osa70859 6988.m00184
Plasmodium falciparum (Pfa) pfa3645 PFE0980c
Rattus norvegicus (Rno) rno10068 ENSRNOP00000002843
(RGD:1309128)
Rattus norvegicus (Rno) rno4885 ENSRNOP00000003752
(RGD:1310783)		 Q6AXU9
Rattus norvegicus (Rno) rno4884 ENSRNOP00000048838
Rattus norvegicus (Rno) rno10069 ENSRNOP00000049364
Saccharomyces cerevisiae (Sce) sce23 YAL021C
(S000000019)
Schizosaccharomyces pombe (Spo) spo2769 SPCC31H12.08c O74874
Yarrowia lipolytica (Yli) yli1369 YALI0B15147g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000000019
GO:0005575 cellular_component C
ND
AthAt3g58560
At3g58580
MmuMGI:2443154
MGI:2144529
GO:0005634 nucleus C
IDA
SpoSPCC31H12.08c
GO:0005737 cytoplasm C
IDA
SceS000000019
GO:0005829 cytosol C
IDA
SpoSPCC31H12.08c
GO:0016593 Cdc73/Paf1 complex C
IPI
SceS000000019
GO:0030015 CCR4-NOT core complex C
IPI
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0003674 molecular_function F
ND
MmuMGI:2144529
GO:0005515 protein binding F
IPI
MmuMGI:2443154
GO:0016787 hydrolase activity F
ISS
AthAt3g58560
At3g58580
GO:0000003 reproduction P
IMP
CelWBGene00000376
GO:0000076 DNA replication checkpoint P
IGI
SceS000000019
GO:0000288 nuclear-transcribed mRNA catabolic process,
deadenylation-dependent decay		 P
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
GO:0000289 nuclear-transcribed mRNA poly(A) tail
shortening		 P
IDA
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0006260 DNA replication P
IGI
SceS000000019
GO:0006354 RNA elongation P
IC
SpoSPCC31H12.08c
RCA
SceS000000019
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IPI
SceS000000019
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IGI
SceS000000019
IMP
SceS000000019
GO:0007089 traversing start control point of mitotic cell
cycle		 P
IMP
SceS000000019
GO:0008150 biological_process P
ND
AthAt3g58560
MmuMGI:2443154
MGI:2144529
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000376
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000376
GO:0040002 collagen and cuticulin-based cuticle
development		 P
IMP
CelWBGene00000376
GO:0040011 locomotion P
IMP
CelWBGene00000376
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00000376
GO:0048478 replication fork protection P
IGI
SceS000000019

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC31H12.08c
(O74874)		 YAL021C
(S000000019)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000932 cytoplasmic mRNA processing body C
IDA
SceS000000019
GO:0005634 nucleus C
IDA
SpoSPCC31H12.08c
GO:0005737 cytoplasm C
IDA
SceS000000019
GO:0005829 cytosol C
IDA
SpoSPCC31H12.08c
GO:0016593 Cdc73/Paf1 complex C
IPI
SceS000000019
GO:0030015 CCR4-NOT core complex C
IPI
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0000175 3'-5'-exoribonuclease activity F
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0000076 DNA replication checkpoint P
IGI
SceS000000019
GO:0000288 nuclear-transcribed mRNA catabolic process,
deadenylation-dependent decay		 P
IDA
SceS000000019
IGI
SceS000000019
IMP
SceS000000019
GO:0000289 nuclear-transcribed mRNA poly(A) tail
shortening		 P
IDA
SceS000000019
IMP
SceS000000019
ISS
SpoSPCC31H12.08c
GO:0006260 DNA replication P
IGI
SceS000000019
GO:0006354 RNA elongation P
IC
SpoSPCC31H12.08c
RCA
SceS000000019
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IPI
SceS000000019
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
IGI
SceS000000019
IMP
SceS000000019
GO:0007089 traversing start control point of mitotic cell
cycle		 P
IMP
SceS000000019
GO:0048478 replication fork protection P
IGI
SceS000000019

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