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Search term: YAL035W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FUN12
SGD link S000000033
Alternative ID YAL035W
Description GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2
Synonyms YAL035W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1144 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Translation initiation factor 5B (eIF-5B)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g21160 GI:15218159
Arabidopsis thaliana (Ath) At1g76720 GI:15223146
Arabidopsis thaliana (Ath) At1g76810 GI:15223733
Arabidopsis thaliana (Ath) At1g76820 GI:6143897
Arabidopsis thaliana (Ath) At2g27700 GI:15226229
Caenorhabditis elegans (Cel) CE27011
(WBGene00021857)		 GI:17556188
Drosophila melanogaster (Dme) 7292367 GI:7292367
Drosophila melanogaster (Dme) 7292368 GI:7292368
Homo sapiens (Hsa) Hs15451892 GI:15451892
Saccharomyces cerevisiae (Sce) YAL035w
(S000000033)		 GI:6319282 P39730
Schizosaccharomyces pombe (Spo) SPAC56F8.03 GI:19114130 Q10251
Encephalitozoon cuniculi (Ecu) ECU09g0070 GI:19173127
Arabidopsis thaliana (Ath) At1g21160 GI:15218159
Arabidopsis thaliana (Ath) At1g76720 GI:15223146
Arabidopsis thaliana (Ath) At1g76810 GI:15223733
Arabidopsis thaliana (Ath) At1g76820 GI:6143897
Arabidopsis thaliana (Ath) At2g27700 GI:15226229
Caenorhabditis elegans (Cel) CE27011
(WBGene00021857)		 GI:17556188
Drosophila melanogaster (Dme) 7292367 GI:7292367
Drosophila melanogaster (Dme) 7292368 GI:7292368
Homo sapiens (Hsa) Hs15451892 GI:15451892
Saccharomyces cerevisiae (Sce) YAL035w
(S000000033)		 GI:6319282 P39730
Schizosaccharomyces pombe (Spo) SPAC56F8.03 GI:19114130 Q10251
Encephalitozoon cuniculi (Ecu) ECU09g0070 GI:19173127


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g21160
At1g76720
At1g76820
GO:0005739 mitochondrion C
IDA
SceS000000033
GO:0005829 cytosol C
IDA
SpoSPAC56F8.03
GO:0005886 plasma membrane C
IDA
AthAt1g76810
GO:0022627 cytosolic small ribosomal subunit C
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0003743 translation initiation factor activity F
IDA
SceS000000033
ISS
AthAt1g76720
At1g21160
SpoSPAC56F8.03
GO:0003924 GTPase activity F
IDA
SceS000000033
IMP
SceS000000033
ISS
SceS000000033
SpoSPAC56F8.03
GO:0005525 GTP binding F
IC
SpoSPAC56F8.03
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g76810
At2g27700
GO:0000003 reproduction P
IMP
CelWBGene00021857
GO:0002119 nematode larval development P
IMP
CelWBGene00021857
GO:0006184 GTP catabolic process P
ISS
SpoSPAC56F8.03
GO:0006413 translational initiation P
IDA
SceS000000033
ISS
AthAt1g76720
SpoSPAC56F8.03
GO:0008150 biological_process P
ND
AthAt1g76820
At1g21160
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021857
GO:0040007 growth P
IMP
CelWBGene00021857
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC56F8.03

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5291

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EIF5B GI:84043963
Pan troglodytes (Ptr) EIF5B GI:114579118
Canis familiaris (Cfa) EIF5B GI:73969383
Mus musculus (Mmu) Eif5b
(MGI:2441772)		 GI:84043961 Q05D44
Rattus norvegicus (Rno) Eif5b
(RGD:735017)		 GI:109485959
Rattus norvegicus (Rno) Eif5b-ps1 GI:109508035
Gallus gallus (Gga) EIF5B GI:84105269
Drosophila melanogaster (Dme) eIF5B
(FBgn0026259)		 GI:24656849
Anopheles gambiae (Aga) AgaP_AGAP004824 GI:118790039
Caenorhabditis elegans (Cel) iffb-1
(CE27011;
WBGene00021857)		 GI:212656558
Schizosaccharomyces pombe (Spo) SPAC56F8.03 GI:19114130 Q10251
Saccharomyces cerevisiae (Sce) FUN12
(S000000033)		 GI:6319282 P39730
Kluyveromyces lactis (Kla) KLLA0F23265g GI:50312169
Eremothecium gossypii (Ego) AGOS_ADR373W GI:45188246
Magnaporthe grisea (Mgr) MGG_06066 GI:145603416
Neurospora crassa (Ncr) NCU05270.1 GI:32408291
Arabidopsis thaliana (Ath) AT1G76810 GI:42563275
Arabidopsis thaliana (Ath) AT1G21160 GI:145335964
Arabidopsis thaliana (Ath) AT1G76720 GI:145337643
Oryza sativa (Osa) Os05g0592600 GI:115465795
Plasmodium falciparum (Pfa) PFF0345w GI:86170667


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g21160
At1g76720
MmuMGI:2441772
GO:0005737 cytoplasm C
ISS
DmeFBgn0026259
GO:0005739 mitochondrion C
IDA
SceS000000033
GO:0005829 cytosol C
IDA
SpoSPAC56F8.03
ISS
DmeFBgn0026259
GO:0005886 plasma membrane C
IDA
AthAt1g76810
GO:0022627 cytosolic small ribosomal subunit C
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0003674 molecular_function F
ND
MmuMGI:2441772
GO:0003743 translation initiation factor activity F
IDA
HsaEIF5B
SceS000000033
ISS
AthAt1g76720
At1g21160
DmeFBgn0026259
SpoSPAC56F8.03
NAS
HsaEIF5B
GO:0003924 GTPase activity F
IDA
SceS000000033
IMP
SceS000000033
ISS
SceS000000033
SpoSPAC56F8.03
GO:0005515 protein binding F
IPI
HsaEIF5B
GO:0005525 GTP binding F
IC
SpoSPAC56F8.03
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g76810
GO:0017151 DEAD/H-box RNA helicase binding F
TAS
DmeFBgn0026259
GO:0000003 reproduction P
IMP
CelWBGene00021857
GO:0002119 nematode larval development P
IMP
CelWBGene00021857
GO:0006184 GTP catabolic process P
ISS
SpoSPAC56F8.03
GO:0006413 translational initiation P
IDA
SceS000000033
ISS
AthAt1g76720
DmeFBgn0026259
SpoSPAC56F8.03
GO:0006446 regulation of translational initiation P
IDA
HsaEIF5B
NAS
HsaEIF5B
GO:0008150 biological_process P
ND
AthAt1g21160
MmuMGI:2441772
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021857
GO:0040007 growth P
IMP
CelWBGene00021857
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC56F8.03

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1001

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga160 ENSANGP00000010768
Anopheles gambiae (Aga) aga161 ENSANGP00000026806
Ashbya gossypii (Ago) ago2114 ADR373W
Arabidopsis thaliana (Ath) ath2269 At1g21160.1
Arabidopsis thaliana (Ath) ath6999 At1g76720.1
Arabidopsis thaliana (Ath) ath7008 At1g76810.1
Arabidopsis thaliana (Ath) ath7010 At1g76825.1
Caenorhabditis elegans (Cel) cel19775 Y54F10BM.2
(CE27011;
WBGene00021857)
Candida glabrata (Cgl) cgl5184 CAGL0M12144g
Cryptococcus neoformans (Cne) cne4676 186.m03527
Dictyostelium discoideum (Ddi) ddi5890 DDB0206214
Debaryomyces hansenii (Dha) dha1959 DEHA0C11968g
Drosophila melanogaster (Dme) dme7800 CG10840-PB
(FBgn0026259)
Danio rerio (Dre) dre25231 ENSDARP00000013232
Encephalitozoon cuniculi (Ecu) ecu1278 19173127
Takifugu rubripes (Fru) fru29180 SINFRUP00000142264
Takifugu rubripes (Fru) fru29181 SINFRUP00000169860
Takifugu rubripes (Fru) fru29184 SINFRUP00000170013
Takifugu rubripes (Fru) fru29185 SINFRUP00000170273
Takifugu rubripes (Fru) fru29182 SINFRUP00000171504
Takifugu rubripes (Fru) fru29183 SINFRUP00000172664
Gallus gallus (Gga) gga2576 ENSGALP00000027015
(EIF5B)
Gallus gallus (Gga) gga2578 ENSGALP00000027017
Homo sapiens (Hsa) hsa18320 ENSP00000289371
(EIF5B)		 O60841
Kluyveromyces lactis (Kla) kla5116 KLLA0F23265g
Mus musculus (Mmu) mmu224 ENSMUSP00000027252
(MGI:2441772)		 Q05D44
Mus musculus (Mmu) mmu21437 ENSMUSP00000079476
Neurospora crassa (Ncr) ncr5115 NCU05270.2
Oryza sativa (Osa) osa48284 5813.m00145
Plasmodium falciparum (Pfa) pfa3034 PFF0345w
Rattus norvegicus (Rno) rno749 ENSRNOP00000014877
Rattus norvegicus (Rno) rno29911 ENSRNOP00000036844
(RGD:735017)		 B2GUV7
Saccharomyces cerevisiae (Sce) sce41 YAL035W
(S000000033)
Schizosaccharomyces pombe (Spo) spo3626 SPAC56F8.03 Q10251
Yarrowia lipolytica (Yli) yli27 YALI0A00803g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g21160
At1g76720
MmuMGI:2441772
GO:0005737 cytoplasm C
ISS
DmeFBgn0026259
GO:0005739 mitochondrion C
IDA
SceS000000033
GO:0005829 cytosol C
IDA
SpoSPAC56F8.03
ISS
DmeFBgn0026259
GO:0005886 plasma membrane C
IDA
AthAt1g76810
GO:0022627 cytosolic small ribosomal subunit C
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0003674 molecular_function F
ND
MmuMGI:2441772
GO:0003743 translation initiation factor activity F
IDA
SceS000000033
ISS
AthAt1g76720
At1g21160
DmeFBgn0026259
SpoSPAC56F8.03
GO:0003924 GTPase activity F
IDA
SceS000000033
IMP
SceS000000033
ISS
SceS000000033
SpoSPAC56F8.03
GO:0005525 GTP binding F
IC
SpoSPAC56F8.03
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g76810
GO:0017151 DEAD/H-box RNA helicase binding F
TAS
DmeFBgn0026259
GO:0000003 reproduction P
IMP
CelWBGene00021857
GO:0002119 nematode larval development P
IMP
CelWBGene00021857
GO:0006184 GTP catabolic process P
ISS
SpoSPAC56F8.03
GO:0006413 translational initiation P
IDA
SceS000000033
ISS
AthAt1g76720
DmeFBgn0026259
SpoSPAC56F8.03
GO:0008150 biological_process P
ND
AthAt1g21160
MmuMGI:2441772
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021857
GO:0040007 growth P
IMP
CelWBGene00021857
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC56F8.03

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC56F8.03
(Q10251)		 YAL035W
(S000000033)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000033
GO:0005829 cytosol C
IDA
SpoSPAC56F8.03
GO:0022627 cytosolic small ribosomal subunit C
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0003743 translation initiation factor activity F
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0003924 GTPase activity F
IDA
SceS000000033
IMP
SceS000000033
ISS
SceS000000033
SpoSPAC56F8.03
GO:0005525 GTP binding F
IC
SpoSPAC56F8.03
GO:0006184 GTP catabolic process P
ISS
SpoSPAC56F8.03
GO:0006413 translational initiation P
IDA
SceS000000033
ISS
SpoSPAC56F8.03
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPAC56F8.03

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Include wild-cards:   

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GO info in one table:

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