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Search term: YAL041W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC24
SGD link S000000039
Alternative ID YAL041W
Description Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing
Synonyms YAL041W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3519 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Invasion-inducing protein TIAM1/CDC24 and related RhoGEF GTPases

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE08100 GI:17505571
Caenorhabditis elegans (Cel) CE24205 GI:17540914
Drosophila melanogaster (Dme) 7291957 GI:7291957 Q8IRJ2
Drosophila melanogaster (Dme) 7295439 GI:7295439
Drosophila melanogaster (Dme) 7295440 GI:7295440
Homo sapiens (Hsa) Hs15011979
(ARHGEF4)
GI:15011979 Q9NR80
Homo sapiens (Hsa) Hs15011981 GI:15011981 Q9NR80
Homo sapiens (Hsa) Hs17447529 GI:17447529
Homo sapiens (Hsa) Hs17466362 GI:17466362
Homo sapiens (Hsa) Hs19882229_1 GI:19882229
Homo sapiens (Hsa) Hs20544361 GI:20544361
Homo sapiens (Hsa) Hs20548486 GI:20548486
Homo sapiens (Hsa) Hs22052726 GI:22052726
Homo sapiens (Hsa) Hs22052729 GI:22052729
Homo sapiens (Hsa) Hs4507501 GI:4507501
Homo sapiens (Hsa) Hs6912704 GI:6912704
Homo sapiens (Hsa) Hs7662108
(ARHGEF9)
GI:7662108 B1AMR3
Homo sapiens (Hsa) Hs8923173
(FLJ20184)
GI:8923173 Q9NXL2
Saccharomyces cerevisiae (Sce) YAL041w
(S000000039)
GI:6319276 P11433
Schizosaccharomyces pombe (Spo) SPAC16E8.09 GI:19115133 P40995
Schizosaccharomyces pombe (Spo) SPAC24H6.09 GI:19113855 Q09763
Schizosaccharomyces pombe (Spo) SPBC29A3.17 GI:19112637 O59679


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000039
GO:0005634 nucleus C
IDA
SceS000000039
SpoSPAC16E8.09
GO:0005737 cytoplasm C
IDA
SceS000000039
SpoSPAC24H6.09
GO:0005819 spindle C
IDA
SpoSPAC16E8.09
GO:0005829 cytosol C
EXP
HsaARHGEF4
ARHGEF9
IDA
SpoSPAC16E8.09
SPBC29A3.17
SPAC24H6.09
GO:0005934 cellular bud tip C
IDA
SceS000000039
GO:0005935 cellular bud neck C
IDA
SceS000000039
GO:0030427 site of polarized growth C
IDA
SpoSPAC16E8.09
GO:0030428 cell septum C
IDA
SpoSPAC24H6.09
GO:0031097 medial cortex C
IDA
SpoSPAC24H6.09
GO:0032153 cell division site C
IDA
SpoSPBC29A3.17
SPAC16E8.09
SPAC24H6.09
GO:0043332 mating projection tip C
IDA
SceS000000039
SpoSPAC16E8.09
GO:0051286 cell tip C
IDA
SpoSPAC16E8.09
GO:0071521 Cdc42 GTPase complex C
TAS
SpoSPAC16E8.09
GO:0005085 guanyl-nucleotide exchange factor
activity
F
EXP
HsaARHGEF4
ARHGEF9
GO:0005089 Rho guanyl-nucleotide exchange factor
activity
F
IDA
SpoSPAC24H6.09
NAS
HsaARHGEF4
TAS
SceS000000039
SpoSPAC16E8.09
SPBC29A3.17
GO:0005515 protein binding F
IPI
HsaARHGEF4
SpoSPAC16E8.09
SPAC24H6.09
GO:0019904 protein domain specific binding F
IPI
HsaARHGEF4
GO:0000750 pheromone-dependent signal transduction involved
in conjugation with cellular fusion
P
IGI
SceS000000039
IPI
SceS000000039
TAS
SceS000000039
GO:0000753 cell morphogenesis involved in conjugation with
cellular fusion
P
IMP
SceS000000039
GO:0001403 invasive growth in response to glucose
limitation
P
IPI
SceS000000039
GO:0006033 chitin localization P
IMP
SceS000000039
GO:0006915 apoptosis P
EXP
HsaARHGEF4
ARHGEF9
GO:0007096 regulation of exit from mitosis P
IMP
SceS000000039
GO:0007118 budding cell apical bud growth P
IPI
SceS000000039
GO:0007119 budding cell isotropic bud growth P
IPI
SceS000000039
GO:0007124 pseudohyphal growth P
IPI
SceS000000039
GO:0007264 small GTPase mediated signal transduction P
TAS
SceS000000039
GO:0008360 regulation of cell shape P
IMP
SpoSPAC16E8.09
GO:0008624 induction of apoptosis by extracellular
signals
P
EXP
HsaARHGEF9
ARHGEF4
GO:0019953 sexual reproduction P
RCA
SceS000000039
GO:0023034 intracellular signaling pathway P
NAS
HsaARHGEF4
GO:0030010 establishment of cell polarity P
TAS
SceS000000039
GO:0030100 regulation of endocytosis P
IMP
SpoSPAC16E8.09
GO:0032005 regulation of conjugation with cellular fusion by
signal transduction
P
IMP
SpoSPAC16E8.09
GO:0032319 regulation of Rho GTPase activity P
IC
SpoSPBC29A3.17
IDA
SpoSPAC24H6.09
GO:0032489 regulation of Cdc42 protein signal
transduction
P
IC
SpoSPAC16E8.09
NAS
SpoSPAC24H6.09
GO:0032878 regulation of establishment or maintenance of cell
polarity
P
IGI
SpoSPAC24H6.09
IMP
SpoSPAC16E8.09
GO:0032887 regulation of spindle elongation P
IMP
SpoSPAC16E8.09
GO:0032955 regulation of barrier septum formation P
IGI
SpoSPAC16E8.09
IMP
SpoSPAC24H6.09
GO:0035023 regulation of Rho protein signal
transduction
P
IC
SpoSPAC24H6.09
SPBC29A3.17
GO:0043088 regulation of Cdc42 GTPase activity P
TAS
SpoSPAC16E8.09

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
29582

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) ral1 GI:19115133
Saccharomyces cerevisiae (Sce) CDC24
(S000000039)
GI:6319276 P11433
Kluyveromyces lactis (Kla) KLLA0C12969g GI:50305635
Eremothecium gossypii (Ego) AGOS_ADR388C GI:45188261


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000039
GO:0005634 nucleus C
IDA
SceS000000039
GO:0005737 cytoplasm C
IDA
SceS000000039
GO:0005934 cellular bud tip C
IDA
SceS000000039
GO:0005935 cellular bud neck C
IDA
SceS000000039
GO:0043332 mating projection tip C
IDA
SceS000000039
GO:0005089 Rho guanyl-nucleotide exchange factor
activity
F
TAS
SceS000000039
GO:0000750 pheromone-dependent signal transduction involved
in conjugation with cellular fusion
P
IGI
SceS000000039
IPI
SceS000000039
TAS
SceS000000039
GO:0000753 cell morphogenesis involved in conjugation with
cellular fusion
P
IMP
SceS000000039
GO:0001403 invasive growth in response to glucose
limitation
P
IPI
SceS000000039
GO:0006033 chitin localization P
IMP
SceS000000039
GO:0007096 regulation of exit from mitosis P
IMP
SceS000000039
GO:0007118 budding cell apical bud growth P
IPI
SceS000000039
GO:0007119 budding cell isotropic bud growth P
IPI
SceS000000039
GO:0007124 pseudohyphal growth P
IPI
SceS000000039
GO:0007264 small GTPase mediated signal transduction P
TAS
SceS000000039
GO:0019953 sexual reproduction P
RCA
SceS000000039
GO:0030010 establishment of cell polarity P
TAS
SceS000000039

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4998

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2129 ADR388C
Candida glabrata (Cgl) cgl5176 CAGL0M11968g
Cryptococcus neoformans (Cne) cne18 162.m02908
Debaryomyces hansenii (Dha) dha3791 DEHA0E12452g
Danio rerio (Dre) dre29015 ENSDARP00000030297
Takifugu rubripes (Fru) fru22940 SINFRUP00000127354
Takifugu rubripes (Fru) fru32540 SINFRUP00000138922
Gallus gallus (Gga) gga11917 ENSGALP00000007346
(PREX1)
Gallus gallus (Gga) gga11211 ENSGALP00000025048
(DEPDC2)
Homo sapiens (Hsa) hsa20384 ENSP00000262976
Homo sapiens (Hsa) hsa30387 ENSP00000288368
(PREX2)
Q70Z35-1
Homo sapiens (Hsa) hsa30389 ENSP00000346707
(PREX2)
Q70Z35-3
Kluyveromyces lactis (Kla) kla1777 KLLA0C12969g
Mus musculus (Mmu) mmu16043 ENSMUSP00000037180
(MGI:3040696)
Q69ZK0-1
Neurospora crassa (Ncr) ncr5897 NCU06067.2
Rattus norvegicus (Rno) rno20302 ENSRNOP00000009517
(RGD:1306534)
Saccharomyces cerevisiae (Sce) sce49 YAL041W
(S000000039)
Schizosaccharomyces pombe (Spo) spo1355 SPAC16E8.09 P40995
Yarrowia lipolytica (Yli) yli2316 YALI0C14828g