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Search term: YAL048C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GEM1
SGD link S000000046
Alternative ID YAL048C
Description Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death
Synonyms YAL048C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1707 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted Ras related/Rac-GTP binding protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g05310 GI:15229963
Arabidopsis thaliana (Ath) At3g63150 GI:11358744
Arabidopsis thaliana (Ath) At5g27540 GI:15240981
Caenorhabditis elegans (Cel) CE04309_1 GI:17539546
Caenorhabditis elegans (Cel) CE08797
(WBGene00016737)
GI:17551068 Q94180
Caenorhabditis elegans (Cel) CE11958
(WBGene00019544)
GI:17541392 Q94263
Caenorhabditis elegans (Cel) CE27262
(WBGene00021651)
GI:17510041 Q9BL82
Drosophila melanogaster (Dme) 7301088 GI:7301088
Homo sapiens (Hsa) HsM8922838 GI:8922838
Homo sapiens (Hsa) Hs21361738 GI:20559586
Homo sapiens (Hsa) Hs20270303
(RHOT2)
GI:20270303 Q8IXI1
Saccharomyces cerevisiae (Sce) YAL048c
(S000000046)
GI:6319268 P39722
Schizosaccharomyces pombe (Spo) SPCC320.04c GI:19075225 O59781


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC320.04c
GO:0005635 nuclear envelope C
IDA
SpoSPCC320.04c
GO:0005739 mitochondrion C
IDA
AthAt3g63150
At5g27540
SceS000000046
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000046
ISS
SpoSPCC320.04c
GO:0005829 cytosol C
IDA
SpoSPCC320.04c
GO:0031307 integral to mitochondrial outer
membrane
C
IDA
HsaRHOT2
GO:0003924 GTPase activity F
IDA
AthAt3g63150
SceS000000046
ISS
SpoSPCC320.04c
GO:0005509 calcium ion binding F
IDA
AthAt3g63150
ISS
SpoSPCC320.04c
GO:0005515 protein binding F
IPI
HsaRHOT2
GO:0005525 GTP binding F
IC
SpoSPCC320.04c
GO:0000001 mitochondrion inheritance P
IGI
SceS000000046
IMP
SceS000000046
GO:0002119 nematode larval development P
IMP
CelWBGene00016737
WBGene00019544
WBGene00021651
GO:0006184 GTP catabolic process P
ISS
SpoSPCC320.04c
GO:0006915 apoptosis P
IMP
HsaRHOT2
GO:0007005 mitochondrion organization P
IMP
AthAt5g27540
ISS
SpoSPCC320.04c
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPCC320.04c
GO:0009737 response to abscisic acid stimulus P
IMP
AthAt3g63150
GO:0009790 embryo development P
IMP
AthAt5g27540
GO:0009793 embryo development ending in seed
dormancy
P
NAS
AthAt5g27540
GO:0009860 pollen tube growth P
IMP
AthAt5g27540
GO:0016192 vesicle-mediated transport P
IGI
SceS000000046
IMP
SceS000000046
ISS
SpoSPCC320.04c
GO:0019725 cellular homeostasis P
IMP
HsaRHOT2
GO:0047497 mitochondrion transport along microtubule P
IMP
HsaRHOT2

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56038

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RHOT2 GI:20270303 Q8IXI1
Pan troglodytes (Ptr) RHOT2 GI:114660192
Canis familiaris (Cfa) RHOT2 GI:73959829
Mus musculus (Mmu) Rhot2
(MGI:2384892)
GI:22122457 Q8JZN7
Rattus norvegicus (Rno) Rhot2
(RGD:727970)
GI:32452540
Gallus gallus (Gga) RCJMB04_2o8 GI:118098206
Schizosaccharomyces pombe (Spo) SPCC320.04c GI:19075225 O59781
Saccharomyces cerevisiae (Sce) GEM1
(S000000046)
GI:6319268 P39722
Kluyveromyces lactis (Kla) KLLA0A03465g GI:50302435
Eremothecium gossypii (Ego) AGOS_ADR402W GI:45188274
Magnaporthe grisea (Mgr) MGG_01044 GI:39973619
Neurospora crassa (Ncr) NCU03966.1 GI:32405344
Arabidopsis thaliana (Ath) MIRO1 GI:79328825
Oryza sativa (Osa) Os03g0810600 GI:115456129
Oryza sativa (Osa) Os01g0843300 GI:115440991


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC320.04c
GO:0005635 nuclear envelope C
IDA
SpoSPCC320.04c
GO:0005739 mitochondrion C
IDA
AthMIRO1
MmuMGI:2384892
SceS000000046
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000046
ISS
SpoSPCC320.04c
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:2384892
GO:0005829 cytosol C
IDA
SpoSPCC320.04c
GO:0031307 integral to mitochondrial outer
membrane
C
IDA
HsaRHOT2
GO:0003674 molecular_function F
ND
MmuMGI:2384892
GO:0003924 GTPase activity F
IDA
SceS000000046
ISS
SpoSPCC320.04c
GO:0005509 calcium ion binding F
ISS
SpoSPCC320.04c
GO:0005515 protein binding F
IPI
HsaRHOT2
GO:0005525 GTP binding F
IC
SpoSPCC320.04c
GO:0000001 mitochondrion inheritance P
IGI
SceS000000046
IMP
SceS000000046
GO:0006184 GTP catabolic process P
ISS
SpoSPCC320.04c
GO:0006915 apoptosis P
IMP
HsaRHOT2
GO:0007005 mitochondrion organization P
IMP
AthMIRO1
ISS
SpoSPCC320.04c
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPCC320.04c
GO:0008150 biological_process P
ND
MmuMGI:2384892
GO:0009790 embryo development P
IMP
AthMIRO1
GO:0009793 embryo development ending in seed
dormancy
P
NAS
AthMIRO1
GO:0009860 pollen tube growth P
IMP
AthMIRO1
GO:0016192 vesicle-mediated transport P
IGI
SceS000000046
IMP
SceS000000046
ISS
SpoSPCC320.04c
GO:0019725 cellular homeostasis P
IMP
HsaRHOT2
GO:0047497 mitochondrion transport along microtubule P
IMP
HsaRHOT2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_607

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9973 ENSANGP00000011857
Ashbya gossypii (Ago) ago2142 ADR402W
Arabidopsis thaliana (Ath) ath17768 At3g63150.1
Arabidopsis thaliana (Ath) ath25027 At5g27540.1
Caenorhabditis elegans (Cel) cel12311 K08F11.5
(CE11958;
WBGene00019544)
Candida glabrata (Cgl) cgl5190 CAGL0M12276g
Cryptococcus neoformans (Cne) cne1248 180.m00187
Dictyostelium discoideum (Ddi) ddi11383 DDB0230033
Debaryomyces hansenii (Dha) dha4858 DEHA0F10725g
Debaryomyces hansenii (Dha) dha4859 DEHA0F10736g
Drosophila melanogaster (Dme) dme14124 CG5410-PD
(FBgn0039140)
Drosophila melanogaster (Dme) dme14125 CG5410-PE
(FBgn0039140)
Danio rerio (Dre) dre18438 ENSDARP00000014131
Danio rerio (Dre) dre31469 ENSDARP00000018179
(tspan7b)
Q642H0
Danio rerio (Dre) dre31468 ENSDARP00000031848
Danio rerio (Dre) dre18439 ENSDARP00000041941
(zgc:110586)
Q503H8
Danio rerio (Dre) dre31504 ENSDARP00000046074
Danio rerio (Dre) dre18437 ENSDARP00000050314
Danio rerio (Dre) dre31503 ENSDARP00000050358
(LOC561933)
Takifugu rubripes (Fru) fru21158 SINFRUP00000156624
Takifugu rubripes (Fru) fru21157 SINFRUP00000156627
Takifugu rubripes (Fru) fru13432 SINFRUP00000156943
Takifugu rubripes (Fru) fru13431 SINFRUP00000156945
Takifugu rubripes (Fru) fru16887 SINFRUP00000167069
Takifugu rubripes (Fru) fru21159 SINFRUP00000171832
Takifugu rubripes (Fru) fru13430 SINFRUP00000173363
Takifugu rubripes (Fru) fru13429 SINFRUP00000173643
Takifugu rubripes (Fru) fru16888 SINFRUP00000176478
Gallus gallus (Gga) gga6258 ENSGALP00000003922
Gallus gallus (Gga) gga6256 ENSGALP00000003923
(RCJMB04_2o8)
Gallus gallus (Gga) gga6259 ENSGALP00000003924
Gallus gallus (Gga) gga6257 ENSGALP00000003925
Gallus gallus (Gga) gga6260 ENSGALP00000003926
(RCJMB04_2o8)
Q5ZM83
Gallus gallus (Gga) gga8511 ENSGALP00000005360
Gallus gallus (Gga) gga8512 ENSGALP00000005361
Gallus gallus (Gga) gga8510 ENSGALP00000005362
(RHOT1)
Q5ZM73
Homo sapiens (Hsa) hsa11369 ENSP00000321971
(RHOT2)
Q8IXI1-1
Homo sapiens (Hsa) hsa13414 ENSP00000334724
(RHOT1)
Q8IXI2-1
Homo sapiens (Hsa) hsa13416 ENSP00000346215
(RHOT1)
Q8IXI2-5
Homo sapiens (Hsa) hsa13415 ENSP00000351132
(RHOT1)
Q8IXI2-3
Kluyveromyces lactis (Kla) kla149 KLLA0A03465g
Mus musculus (Mmu) mmu4370 ENSMUSP00000017831
(MGI:1926078)
Q8BG51-2
Mus musculus (Mmu) mmu11182 ENSMUSP00000044639
(MGI:2384892)
Mus musculus (Mmu) mmu4371 ENSMUSP00000076664
(MGI:1926078)
Q8BG51-4
Neurospora crassa (Ncr) ncr3853 NCU03966.2
Oryza sativa (Osa) osa13335 2927.m00139
Oryza sativa (Osa) osa54576 6311.m00193
Oryza sativa (Osa) osa86960 9221.m00132
Oryza sativa (Osa) osa87545 9555.m00173
Rattus norvegicus (Rno) rno5694 ENSRNOP00000006218
(RGD:1305252)
A1L1L6
Rattus norvegicus (Rno) rno5693 ENSRNOP00000007271
(RGD:1305252)
Rattus norvegicus (Rno) rno4694 ENSRNOP00000027083
(RGD:727970)
Q7TSA0
Saccharomyces cerevisiae (Sce) sce59 YAL048C
(S000000046)
Schizosaccharomyces pombe (Spo) spo3240 SPCC320.04c O59781
Yarrowia lipolytica (Yli) yli5657 YALI0F07491g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC320.04c
GO:0005635 nuclear envelope C
IDA
SpoSPCC320.04c
GO:0005739 mitochondrion C
IDA
AthAt3g63150
At5g27540
MmuMGI:2384892
MGI:1926078
SceS000000046
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000046
ISS
SpoSPCC320.04c
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:2384892
GO:0005829 cytosol C
IDA
SpoSPCC320.04c
GO:0031307 integral to mitochondrial outer
membrane
C
ISS
DmeFBgn0039140
GO:0003674 molecular_function F
ND
MmuMGI:1926078
MGI:2384892
GO:0003924 GTPase activity F
IDA
AthAt3g63150
SceS000000046
ISS
SpoSPCC320.04c
GO:0005509 calcium ion binding F
IDA
AthAt3g63150
ISS
SpoSPCC320.04c
GO:0005525 GTP binding F
IC
SpoSPCC320.04c
GO:0000001 mitochondrion inheritance P
IGI
SceS000000046
IMP
SceS000000046
GO:0000226 microtubule cytoskeleton organization P
IMP
DmeFBgn0039140
GO:0002119 nematode larval development P
IMP
CelWBGene00019544
GO:0006184 GTP catabolic process P
ISS
SpoSPCC320.04c
GO:0006915 apoptosis P
ISS
DmeFBgn0039140
GO:0007005 mitochondrion organization P
IMP
AthAt5g27540
ISS
SpoSPCC320.04c
GO:0007264 small GTPase mediated signal transduction P
IC
SpoSPCC320.04c
GO:0007268 synaptic transmission P
IMP
DmeFBgn0039140
GO:0008150 biological_process P
ND
MmuMGI:1926078
MGI:2384892
GO:0009737 response to abscisic acid stimulus P
IMP
AthAt3g63150
GO:0009790 embryo development P
IMP
AthAt5g27540
GO:0009793 embryo development ending in seed
dormancy
P
NAS
AthAt5g27540
GO:0009860 pollen tube growth P
IMP
AthAt5g27540
GO:0016192 vesicle-mediated transport P
IGI
SceS000000046
IMP
SceS000000046
ISS
SpoSPCC320.04c
GO:0019725 cellular homeostasis P
ISS
DmeFBgn0039140
GO:0031122 cytoplasmic microtubule organization P
IMP
DmeFBgn0039140
GO:0034643 mitochondrion localization, microtubule-mediated P
IMP
DmeFBgn0039140
GO:0047497 mitochondrion transport along microtubule P
ISS
DmeFBgn0039140
GO:0048489 synaptic vesicle transport P
IMP
DmeFBgn0039140
GO:0051646 mitochondrion localization P
IMP
DmeFBgn0039140

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC320.04c
(O59781)
YAL048C
(S000000046)