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Search term: YAL054C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ACS1
SGD link S000000050
Alternative ID YAL054C
Description Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions
Synonyms YAL054C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1175 ACDHYPE

KOGs classification KOGs description
METABOLISM Acyl-CoA synthetase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g55320 GI:15222694
Arabidopsis thaliana (Ath) At5g23050 GI:15237200
Arabidopsis thaliana (Ath) At5g36880 GI:15239431
Caenorhabditis elegans (Cel) CE03076
(WBGene00007969)		 GI:17552528
Caenorhabditis elegans (Cel) CE04713
(WBGene00006351)		 GI:17569507 Q21166
Drosophila melanogaster (Dme) 7296408 GI:7296408
Drosophila melanogaster (Dme) 7301149 GI:7301149
Homo sapiens (Hsa) Hs12965199 GI:12965199
Homo sapiens (Hsa) Hs13375727
(ACSS3)		 GI:13375727 Q9H6R3
Homo sapiens (Hsa) Hs16418449 GI:16418449
Homo sapiens (Hsa) Hs17484820 GI:17484820
Homo sapiens (Hsa) Hs18574462 GI:18574462
Homo sapiens (Hsa) Hs18586509 GI:18586509
Homo sapiens (Hsa) Hs20561536 GI:20561536
Homo sapiens (Hsa) Hs21269872 GI:21269872
Homo sapiens (Hsa) Hs22052386 GI:22052386
Homo sapiens (Hsa) Hs22061611 GI:22061611
Homo sapiens (Hsa) Hs5032065 GI:5032065
Homo sapiens (Hsa) Hs8923543 GI:8923543
Homo sapiens (Hsa) Hs8923896
(ACSS2)		 GI:8923896 Q9H9U4
Saccharomyces cerevisiae (Sce) YAL054c
(S000000050)		 GI:6319264 Q01574
Saccharomyces cerevisiae (Sce) YLR153c
(S000004143)		 GI:6323182 P52910
Schizosaccharomyces pombe (Spo) SPCC417.14c GI:19075791
Encephalitozoon cuniculi (Ecu) ECU05g0310 GI:19173568 Q8SRZ9
Arabidopsis thaliana (Ath) At1g55320 GI:15222694
Arabidopsis thaliana (Ath) At5g23050 GI:15237200
Arabidopsis thaliana (Ath) At5g36880 GI:15239431
Caenorhabditis elegans (Cel) CE03076
(WBGene00007969)		 GI:17552528
Caenorhabditis elegans (Cel) CE04713
(WBGene00006351)		 GI:17569507 Q21166
Drosophila melanogaster (Dme) 7296408 GI:7296408
Drosophila melanogaster (Dme) 7301149 GI:7301149
Homo sapiens (Hsa) Hs12965199 GI:12965199
Homo sapiens (Hsa) Hs13375727
(ACSS3)		 GI:13375727 Q9H6R3
Homo sapiens (Hsa) Hs16418449 GI:16418449
Homo sapiens (Hsa) Hs17484820 GI:17484820
Homo sapiens (Hsa) Hs18574462 GI:18574462
Homo sapiens (Hsa) Hs18586509 GI:18586509
Homo sapiens (Hsa) Hs20561536 GI:20561536
Homo sapiens (Hsa) Hs21269872 GI:21269872
Homo sapiens (Hsa) Hs22052386 GI:22052386
Homo sapiens (Hsa) Hs22061611 GI:22061611
Homo sapiens (Hsa) Hs5032065 GI:5032065
Homo sapiens (Hsa) Hs8923543 GI:8923543
Homo sapiens (Hsa) Hs8923896
(ACSS2)		 GI:8923896 Q9H9U4
Saccharomyces cerevisiae (Sce) YAL054c
(S000000050)		 GI:6319264 Q01574
Saccharomyces cerevisiae (Sce) YLR153c
(S000004143)		 GI:6323182 P52910
Schizosaccharomyces pombe (Spo) SPCC417.14c GI:19075791
Encephalitozoon cuniculi (Ecu) ECU05g0310 GI:19173568 Q8SRZ9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g23050
GO:0005634 nucleus C
IDA
HsaACSS2
SceS000004143
GO:0005730 nucleolus C
IDA
SceS000004143
GO:0005737 cytoplasm C
IC
HsaACSS2
IDA
HsaACSS2
GO:0005739 mitochondrion C
IDA
SceS000000050
GO:0005777 peroxisome C
IDA
AthAt1g55320
GO:0005829 cytosol C
EXP
HsaACSS2
IDA
AthAt5g36880
SceS000000050
S000004143
GO:0009507 chloroplast C
IDA
AthAt5g36880
GO:0009570 chloroplast stroma C
IDA
AthAt5g36880
GO:0043231 intracellular membrane-bounded
organelle		 C
IDA
HsaACSS2
GO:0003987 acetate-CoA ligase activity F
EXP
HsaACSS2
IDA
HsaACSS2
SceS000000050
S000004143
IMP
AthAt5g36880
GO:0005515 protein binding F
IPI
HsaACSS2
GO:0016208 AMP binding F
IC
HsaACSS2
GO:0016874 ligase activity F
ISS
AthAt5g23050
At1g55320
GO:0001302 replicative cell aging P
IMP
SceS000004143
GO:0006066 alcohol metabolic process P
RCA
SceS000004143
GO:0006083 acetate metabolic process P
IMP
AthAt5g36880
GO:0006085 acetyl-CoA biosynthetic process P
IDA
SceS000000050
S000004143
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000050
GO:0008152 metabolic process P
ISS
AthAt5g36880
At5g23050
At1g55320
GO:0008610 lipid biosynthetic process P
IMP
HsaACSS2
GO:0009850 auxin metabolic process P
IMP
AthAt1g55320
GO:0016573 histone acetylation P
IGI
SceS000000050
IMP
SceS000004143
GO:0019654 acetate fermentation P
IMP
SceS000000050
GO:0019915 lipid storage P
IMP
CelWBGene00007969
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004143

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56037

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ACSS1 GI:28416953
Pan troglodytes (Ptr) ACSS1 GI:114681327
Canis familiaris (Cfa) ACSS1 GI:73989844
Mus musculus (Mmu) Acss1
(MGI:1915988)		 GI:18034773 Q3TZ45
Rattus norvegicus (Rno) Acss1 GI:109468951
Gallus gallus (Gga) ACSS1 GI:118087758
Saccharomyces cerevisiae (Sce) ACS1
(S000000050)		 GI:6319264 Q01574
Kluyveromyces lactis (Kla) ACS1_KLULA GI:50302423
Eremothecium gossypii (Ego) AGOS_ADR408W GI:45188280


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1915988
SceS000000050
ISO
MmuMGI:1915988
GO:0005759 mitochondrial matrix C
EXP
HsaACSS1
IDA
HsaACSS1
MmuMGI:1915988
GO:0005829 cytosol C
IDA
SceS000000050
GO:0003987 acetate-CoA ligase activity F
EXP
HsaACSS1
IDA
HsaACSS1
MmuMGI:1915988
SceS000000050
ISO
MmuMGI:1915988
GO:0005515 protein binding F
IPI
HsaACSS1
GO:0006085 acetyl-CoA biosynthetic process P
IDA
HsaACSS1
MmuMGI:1915988
SceS000000050
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000050
GO:0016573 histone acetylation P
IGI
SceS000000050
GO:0019413 acetate biosynthetic process P
ISO
MmuMGI:1915988
GO:0019542 propionate biosynthetic process P
ISO
MmuMGI:1915988
GO:0019654 acetate fermentation P
IMP
SceS000000050

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_150

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2014 ENSANGP00000011498
Anopheles gambiae (Aga) aga13826 ENSANGP00000014620
Ashbya gossypii (Ago) ago2148 ADR408W
Ashbya gossypii (Ago) ago4164 AGL148C
Arabidopsis thaliana (Ath) ath25436 At5g36880.1
Caenorhabditis elegans (Cel) cel3554 C36A4.9a
(CE03076;
WBGene00007969)
Caenorhabditis elegans (Cel) cel3555 C36A4.9b
(CE37209)
Candida glabrata (Cgl) cgl323 CAGL0B02717g
Candida glabrata (Cgl) cgl4106 CAGL0L00649g
Cryptococcus neoformans (Cne) cne2476 181.m08517
Dictyostelium discoideum (Ddi) ddi12792 DDB0231684
Debaryomyces hansenii (Dha) dha2917 DEHA0D13860g
Debaryomyces hansenii (Dha) dha3524 DEHA0E06446g
Drosophila melanogaster (Dme) dme10549 CG9390-PA
(FBgn0012034)
Danio rerio (Dre) dre7761 ENSDARP00000017303
Danio rerio (Dre) dre7766 ENSDARP00000017565
Danio rerio (Dre) dre7763 ENSDARP00000041948
Danio rerio (Dre) dre7770 ENSDARP00000042305
Danio rerio (Dre) dre7767 ENSDARP00000043144
Danio rerio (Dre) dre7762 ENSDARP00000044327
(zgc:113194)		 Q5BLJ0
Danio rerio (Dre) dre7765 ENSDARP00000045284
Danio rerio (Dre) dre7764 ENSDARP00000046653
Danio rerio (Dre) dre7769 ENSDARP00000047529
Danio rerio (Dre) dre7768 ENSDARP00000049724
Escherichia coli (Eco) eco3914 16131895
Encephalitozoon cuniculi (Ecu) ecu1130 19173568
Takifugu rubripes (Fru) fru24429 SINFRUP00000149956
Takifugu rubripes (Fru) fru32906 SINFRUP00000154103
Takifugu rubripes (Fru) fru24040 SINFRUP00000158168
Takifugu rubripes (Fru) fru8249 SINFRUP00000163774
Takifugu rubripes (Fru) fru8248 SINFRUP00000163778
Takifugu rubripes (Fru) fru32902 SINFRUP00000166788
Takifugu rubripes (Fru) fru32909 SINFRUP00000167221
Takifugu rubripes (Fru) fru24042 SINFRUP00000170729
Takifugu rubripes (Fru) fru32903 SINFRUP00000173368
Takifugu rubripes (Fru) fru32905 SINFRUP00000173507
Takifugu rubripes (Fru) fru32908 SINFRUP00000173931
Takifugu rubripes (Fru) fru32904 SINFRUP00000174377
Takifugu rubripes (Fru) fru32907 SINFRUP00000174832
Takifugu rubripes (Fru) fru24041 SINFRUP00000175577
Gallus gallus (Gga) gga11786 ENSGALP00000005305
Gallus gallus (Gga) gga11788 ENSGALP00000005306
Gallus gallus (Gga) gga11787 ENSGALP00000005307
Gallus gallus (Gga) gga11785 ENSGALP00000005308
(ACSS2)
Gallus gallus (Gga) gga6908 ENSGALP00000014052
(ACSS1)
Gallus gallus (Gga) gga6906 ENSGALP00000014053
Gallus gallus (Gga) gga19531 ENSGALP00000016602
Gallus gallus (Gga) gga19532 ENSGALP00000016603
Gallus gallus (Gga) gga19533 ENSGALP00000016604
(LOC423347)
Homo sapiens (Hsa) hsa20087 ENSP00000253382
(ACSS2)		 Q5QPH3
Homo sapiens (Hsa) hsa19951 ENSP00000316924
(ACSS1)		 Q9NUB1-1
Homo sapiens (Hsa) hsa20084 ENSP00000337190
(ACSS2)		 Q4G0E8
Homo sapiens (Hsa) hsa20085 ENSP00000350076
Homo sapiens (Hsa) hsa20086 ENSP00000353804
(ACSS2)		 Q9NR19
Kluyveromyces lactis (Kla) kla143 KLLA0A03333g
Kluyveromyces lactis (Kla) kla2826 KLLA0D17336g
Mus musculus (Mmu) mmu15709 ENSMUSP00000028944
(MGI:1915988)		 Q99NB1
Mus musculus (Mmu) mmu15838 ENSMUSP00000029135
(MGI:1890410)		 Q8BK97
Mus musculus (Mmu) mmu15839 ENSMUSP00000068776
(MGI:1890410)		 A2AQN5
Neurospora crassa (Ncr) ncr6650 NCU06836.2
Oryza sativa (Osa) osa25378 3844.m00174
Oryza sativa (Osa) osa25547 3849.m00143
Plasmodium falciparum (Pfa) pfa3164 PFF1350c
Rattus norvegicus (Rno) rno19946 ENSRNOP00000009627
(RGD:1306246)
Rattus norvegicus (Rno) rno20087 ENSRNOP00000025612
(RGD:1305489)
Rattus norvegicus (Rno) rno20086 ENSRNOP00000046978
Saccharomyces cerevisiae (Sce) sce63 YAL054C
(S000000050)
Saccharomyces cerevisiae (Sce) sce4237 YLR153C
(S000004143)
Schizosaccharomyces pombe (Spo) spo3732 SPCC191.02c P78773
Yarrowia lipolytica (Yli) yli5593 YALI0F05962g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004143
SpoSPCC191.02c
GO:0005730 nucleolus C
IDA
SceS000004143
GO:0005737 cytoplasm C
IDA
MmuMGI:1890410
ISO
MmuMGI:1890410
NAS
DmeFBgn0012034
GO:0005739 mitochondrion C
IDA
MmuMGI:1915988
SceS000000050
ISO
MmuMGI:1915988
ISS
SpoSPCC191.02c
GO:0005759 mitochondrial matrix C
IDA
MmuMGI:1915988
GO:0005829 cytosol C
IDA
AthAt5g36880
SceS000000050
S000004143
SpoSPCC191.02c
ISS
SpoSPCC191.02c
GO:0009507 chloroplast C
IDA
AthAt5g36880
GO:0009570 chloroplast stroma C
IDA
AthAt5g36880
GO:0003987 acetate-CoA ligase activity F
IDA
MmuMGI:1915988
MGI:1890410
SceS000000050
S000004143
IMP
AthAt5g36880
ISO
MmuMGI:1915988
MGI:1890410
ISS
DmeFBgn0012034
PfaPFF1350c
SpoSPCC191.02c
NAS
DmeFBgn0012034
GO:0016208 AMP binding F
ISS
SpoSPCC191.02c
GO:0001302 replicative cell aging P
IMP
SceS000004143
GO:0006066 alcohol metabolic process P
RCA
SceS000004143
GO:0006083 acetate metabolic process P
IMP
AthAt5g36880
GO:0006084 acetyl-CoA metabolic process P
ISS
SpoSPCC191.02c
GO:0006085 acetyl-CoA biosynthetic process P
IDA
MmuMGI:1915988
MGI:1890410
SceS000000050
S000004143
GO:0006091 generation of precursor metabolites and
energy		 P
ISS
PfaPFF1350c
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000050
GO:0008152 metabolic process P
ISS
AthAt5g36880
NAS
DmeFBgn0012034
GO:0016573 histone acetylation P
IGI
SceS000000050
IMP
SceS000004143
GO:0019413 acetate biosynthetic process P
ISO
MmuMGI:1915988
MGI:1890410
GO:0019542 propionate biosynthetic process P
ISO
MmuMGI:1915988
MGI:1890410
GO:0019654 acetate fermentation P
IMP
SceS000000050
ISS
SpoSPCC191.02c
GO:0019915 lipid storage P
IMP
CelWBGene00007969
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004143

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC191.02c
(P78773)		 YAL054C
(S000000050)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC191.02c
GO:0005739 mitochondrion C
IDA
SceS000000050
ISS
SpoSPCC191.02c
GO:0005829 cytosol C
IDA
SceS000000050
SpoSPCC191.02c
ISS
SpoSPCC191.02c
GO:0003987 acetate-CoA ligase activity F
IDA
SceS000000050
ISS
SpoSPCC191.02c
GO:0016208 AMP binding F
ISS
SpoSPCC191.02c
GO:0006084 acetyl-CoA metabolic process P
ISS
SpoSPCC191.02c
GO:0006085 acetyl-CoA biosynthetic process P
IDA
SceS000000050
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000050
GO:0016573 histone acetylation P
IGI
SceS000000050
GO:0019654 acetate fermentation P
IMP
SceS000000050
ISS
SpoSPCC191.02c

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s.khadayate@ucl.ac.uk