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Search term: YAL056W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GPB2
SGD link S000000052
Alternative ID YAL056W
Description Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p
Synonyms YAL056W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40380

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) GPB2
(S000000052)
GI:41629666
Saccharomyces cerevisiae (Sce) GPB1
(S000005898)
GI:6324947
Kluyveromyces lactis (Kla) KLLA0F00374g GI:50310153
Eremothecium gossypii (Ego) AGOS_ADR414C GI:45188286


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000052
S000005898
GO:0005739 mitochondrion C
IDA
SceS000000052
GO:0005886 plasma membrane C
IDA
SceS000000052
IGI
SceS000005898
GO:0004862 cAMP-dependent protein kinase inhibitor
activity
F
IGI
SceS000000052
S000005898
IPI
SceS000000052
GO:0004871 signal transducer activity F
IPI
SceS000000052
S000005898
GO:0032794 GTPase activating protein binding F
IPI
SceS000000052
S000005898
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000000052
S000005898
IMP
SceS000005898
S000000052
GO:0007124 pseudohyphal growth P
IGI
SceS000005898
S000000052
IMP
SceS000005898
S000000052
GO:0007165 signal transduction P
IPI
SceS000005898
S000000052
GO:0009743 response to carbohydrate stimulus P
RCA
SceS000005898
GO:0010255 glucose mediated signaling pathway P
IGI
SceS000005898
S000000052
IMP
SceS000000052
S000005898
GO:0030437 ascospore formation P
IMP
SceS000000052
GO:0042326 negative regulation of phosphorylation P
IGI
SceS000005898
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000005898
IMP
SceS000005898
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000000052
GO:0046580 negative regulation of Ras protein signal
transduction
P
IGI
SceS000000052
S000005898

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_17664

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2154 ADR414C
Candida glabrata (Cgl) cgl3308 CAGL0J07282g
Candida glabrata (Cgl) cgl4105 CAGL0L00627g
Debaryomyces hansenii (Dha) dha6562 DEHA0G19261g
Kluyveromyces lactis (Kla) kla4095 KLLA0F00374g
Saccharomyces cerevisiae (Sce) sce66 YAL056W
(S000000052)
Saccharomyces cerevisiae (Sce) sce6126 YOR371C
(S000005898)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000052
S000005898
GO:0005739 mitochondrion C
IDA
SceS000000052
GO:0005886 plasma membrane C
IDA
SceS000000052
IGI
SceS000005898
GO:0004862 cAMP-dependent protein kinase inhibitor
activity
F
IGI
SceS000000052
S000005898
IPI
SceS000000052
GO:0004871 signal transducer activity F
IPI
SceS000000052
S000005898
GO:0032794 GTPase activating protein binding F
IPI
SceS000000052
S000005898
GO:0001403 invasive growth in response to glucose
limitation
P
IGI
SceS000000052
S000005898
IMP
SceS000005898
S000000052
GO:0007124 pseudohyphal growth P
IGI
SceS000005898
S000000052
IMP
SceS000005898
S000000052
GO:0007165 signal transduction P
IPI
SceS000005898
S000000052
GO:0009743 response to carbohydrate stimulus P
RCA
SceS000005898
GO:0010255 glucose mediated signaling pathway P
IGI
SceS000005898
S000000052
IMP
SceS000000052
S000005898
GO:0030437 ascospore formation P
IMP
SceS000000052
GO:0042326 negative regulation of phosphorylation P
IGI
SceS000005898
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000005898
IMP
SceS000005898
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000000052
GO:0046580 negative regulation of Ras protein signal
transduction
P
IGI
SceS000000052
S000005898

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GO info in one table:

s.khadayate@ucl.ac.uk