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Search term: YAL062W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GDH3
SGD link S000000058
Alternative ID YAL062W
Description NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
Synonyms YAL062W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2250 ACDHYP-

KOGs classification KOGs description
METABOLISM Glutamate/leucine/phenylalanine/valine dehydrogenases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g51720 GI:15218022
Arabidopsis thaliana (Ath) At3g03910 GI:15228667
Arabidopsis thaliana (Ath) At5g07440 GI:15240793
Arabidopsis thaliana (Ath) At5g18170 GI:15238762
Caenorhabditis elegans (Cel) CE06652
(WBGene00014095)		 GI:17544676 Q23621
Drosophila melanogaster (Dme) 7300986 GI:7300986
Drosophila melanogaster (Dme) 7301074 GI:7301074
Homo sapiens (Hsa) Hs4885281
(GLUD1)		 GI:4885281 P00367
Homo sapiens (Hsa) Hs18588772 GI:18588772
Homo sapiens (Hsa) Hs6912392 GI:6912392
Saccharomyces cerevisiae (Sce) YAL062w
(S000000058)		 GI:6319256 P39708
Saccharomyces cerevisiae (Sce) YDL215c
(S000002374)		 GI:6319986 P33327
Saccharomyces cerevisiae (Sce) YOR375c
(S000005902)		 GI:6324951 P07262
Schizosaccharomyces pombe (Spo) SPCC132.04c GI:19075649 Q9USN5
Schizosaccharomyces pombe (Spo) SPCC622.12c GI:19075684 P78804


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g51720
GO:0005625 soluble fraction C
IDA
SceS000005902
S000000058
GO:0005634 nucleus C
IDA
SceS000005902
S000000058
ISS
SpoSPCC622.12c
GO:0005737 cytoplasm C
IDA
HsaGLUD1
SceS000005902
ISS
SpoSPCC622.12c
GO:0005739 mitochondrion C
IDA
AthAt5g18170
At3g03910
At5g07440
HsaGLUD1
SceS000002374
S000000058
ISS
SpoSPCC622.12c
GO:0005829 cytosol C
IDA
SpoSPCC132.04c
SPCC622.12c
GO:0005886 plasma membrane C
IDA
AthAt5g07440
GO:0004352 glutamate dehydrogenase activity F
IDA
AthAt5g07440
HsaGLUD1
IMP
SceS000002374
ISS
SceS000002374
SpoSPCC132.04c
GO:0004353 glutamate dehydrogenase [NAD(P)+]
activity		 F
IDA
AthAt5g07440
At5g18170
HsaGLUD1
IMP
AthAt5g18170
GO:0004354 glutamate dehydrogenase (NADP+)
activity		 F
IDA
SceS000005902
S000000058
IMP
SceS000000058
S000005902
ISS
SceS000000058
SpoSPCC622.12c
GO:0005507 copper ion binding F
IDA
AthAt5g07440
At5g18170
GO:0005515 protein binding F
IPI
HsaGLUD1
GO:0005524 ATP binding F
IDA
AthAt5g07440
At5g18170
GO:0005525 GTP binding F
IDA
HsaGLUD1
GO:0008270 zinc ion binding F
IDA
AthAt5g18170
At5g07440
GO:0016491 oxidoreductase activity F
ISS
AthAt1g51720
At5g18170
At3g03910
At5g07440
GO:0042802 identical protein binding F
TAS
HsaGLUD1
GO:0043531 ADP binding F
IDA
HsaGLUD1
GO:0050897 cobalt ion binding F
IDA
AthAt5g18170
At5g07440
GO:0070403 NAD binding F
IDA
HsaGLUD1
GO:0070728 leucine binding F
IDA
HsaGLUD1
GO:0000003 reproduction P
IMP
CelWBGene00014095
GO:0006536 glutamate metabolic process P
ISS
SpoSPCC132.04c
GO:0006537 glutamate biosynthetic process P
IDA
HsaGLUD1
IGI
SceS000005902
S000000058
IMP
SceS000000058
ISS
SpoSPCC622.12c
GO:0006538 glutamate catabolic process P
IDA
HsaGLUD1
GO:0006807 nitrogen compound metabolic process P
IMP
AthAt5g18170
SceS000002374
GO:0009646 response to absence of light P
IEP
AthAt5g18170
GO:0009651 response to salt stress P
IEP
AthAt5g07440
At5g18170
GO:0019459 glutamate deamidation P
IDA
HsaGLUD1
GO:0019676 ammonia assimilation cycle P
IEP
SceS000005902
S000000058
ISS
SpoSPCC622.12c
GO:0032024 positive regulation of insulin
secretion		 P
IMP
HsaGLUD1
GO:0040007 growth P
IMP
CelWBGene00014095
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00014095
GO:0046686 response to cadmium ion P
IEP
AthAt5g07440
At5g18170
GO:0051171 regulation of nitrogen compound metabolic
process		 P
IEP
AthAt3g03910

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56339

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPCC622.12c GI:19075684 P78804
Saccharomyces cerevisiae (Sce) GDH1
(S000005902)		 GI:6324951 P07262
Saccharomyces cerevisiae (Sce) GDH3
(S000000058)		 GI:6319256 P39708
Magnaporthe grisea (Mgr) MGG_08074 GI:145612065
Neurospora crassa (Ncr) NCU01195.1 GI:32412416
Arabidopsis thaliana (Ath) AT1G51720 GI:30695050
Oryza sativa (Osa) Os01g0558200 GI:115437596
Plasmodium falciparum (Pfa) PF14_0286 GI:124808990
Plasmodium falciparum (Pfa) PF14_0164 GI:124808527


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g51720
PfaPF14_0164
GO:0005625 soluble fraction C
IDA
SceS000005902
S000000058
GO:0005634 nucleus C
IDA
SceS000005902
S000000058
ISS
SpoSPCC622.12c
GO:0005737 cytoplasm C
IDA
SceS000005902
ISS
SpoSPCC622.12c
GO:0005739 mitochondrion C
IDA
SceS000000058
ISS
SpoSPCC622.12c
GO:0005829 cytosol C
IDA
SpoSPCC622.12c
GO:0020011 apicoplast C
ISS
PfaPF14_0286
GO:0004354 glutamate dehydrogenase (NADP+)
activity		 F
IDA
PfaPF14_0164
SceS000005902
S000000058
IMP
SceS000000058
S000005902
ISS
PfaPF14_0286
SceS000000058
SpoSPCC622.12c
GO:0016491 oxidoreductase activity F
ISS
AthAt1g51720
GO:0006536 glutamate metabolic process P
ISS
PfaPF14_0164
GO:0006537 glutamate biosynthetic process P
IGI
SceS000005902
S000000058
IMP
SceS000000058
ISS
SpoSPCC622.12c
GO:0019676 ammonia assimilation cycle P
IEP
SceS000005902
S000000058
ISS
SpoSPCC622.12c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_370

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6905 ENSANGP00000013061
Anopheles gambiae (Aga) aga7185 ENSANGP00000021599
Anopheles gambiae (Aga) aga6908 ENSANGP00000023689
Anopheles gambiae (Aga) aga6907 ENSANGP00000025315
Anopheles gambiae (Aga) aga6906 ENSANGP00000025473
Arabidopsis thaliana (Ath) ath4446 At1g51720.1
Arabidopsis thaliana (Ath) ath12423 At3g03910.1
Arabidopsis thaliana (Ath) ath22956 At5g07440.1
Arabidopsis thaliana (Ath) ath24061 At5g18170.1
Caenorhabditis elegans (Cel) cel22260 ZK829.4
(CE06652;
WBGene00014095)
Candida glabrata (Cgl) cgl666 CAGL0D00176g
Cryptococcus neoformans (Cne) cne5241 179.m00088
Dictyostelium discoideum (Ddi) ddi13222 DDB0231438
Debaryomyces hansenii (Dha) dha2248 DEHA0C18480g
Drosophila melanogaster (Dme) dme14000 CG4434-PA
(FBgn0039071)
Drosophila melanogaster (Dme) dme14101 CG5320-PA
(FBgn0001098)
Drosophila melanogaster (Dme) dme14103 CG5320-PB
(FBgn0001098)
Drosophila melanogaster (Dme) dme14100 CG5320-PF
(FBgn0001098)
Danio rerio (Dre) dre29046 ENSDARP00000008646
(glud1a)		 Q6NZ29
Danio rerio (Dre) dre3635 ENSDARP00000017123
(glud1b)		 Q6P3L9
Escherichia coli (Eco) eco1717 16129715
Takifugu rubripes (Fru) fru21704 SINFRUP00000143914
Takifugu rubripes (Fru) fru24024 SINFRUP00000158102
Gallus gallus (Gga) gga20144 ENSGALP00000003139
(GLUD1)		 P00368
Homo sapiens (Hsa) hsa4238 ENSP00000277865
(GLUD1)		 P00367
Homo sapiens (Hsa) hsa33334 ENSP00000327589
(GLUD2)		 P49448
Kluyveromyces lactis (Kla) kla4105 KLLA0F00594g
Mus musculus (Mmu) mmu7942 ENSMUSP00000022322
(MGI:95753)		 P26443
Neurospora crassa (Ncr) ncr1158 NCU01195.2
Oryza sativa (Osa) osa13125 2860.m00163
Oryza sativa (Osa) osa36506 4935.m00161
Oryza sativa (Osa) osa39254 4987.m00168
Oryza sativa (Osa) osa62421 6675.m00208
Oryza sativa (Osa) osa62473 6675.m00252
Oryza sativa (Osa) osa62477 6675.m00255
Oryza sativa (Osa) osa80989 8208.m00133
Plasmodium falciparum (Pfa) pfa1527 PF14_0164
Plasmodium falciparum (Pfa) pfa1737 PF14_0286
Rattus norvegicus (Rno) rno12078 ENSRNOP00000013789
(RGD:2708)		 P10860
Saccharomyces cerevisiae (Sce) sce72 YAL062W
(S000000058)
Saccharomyces cerevisiae (Sce) sce6130 YOR375C
(S000005902)
Schizosaccharomyces pombe (Spo) spo3410 SPCC622.12c P78804
Yarrowia lipolytica (Yli) yli6091 YALI0F17820g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g51720
PfaPF14_0164
GO:0005625 soluble fraction C
IDA
SceS000005902
S000000058
GO:0005634 nucleus C
IDA
SceS000005902
S000000058
ISS
SpoSPCC622.12c
GO:0005737 cytoplasm C
IDA
SceS000005902
ISS
SpoSPCC622.12c
GO:0005739 mitochondrion C
IDA
AthAt5g18170
At3g03910
At5g07440
DmeFBgn0001098
MmuMGI:95753
SceS000000058
ISO
MmuMGI:95753
ISS
SpoSPCC622.12c
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:95753
GO:0005759 mitochondrial matrix C
IDA
DmeFBgn0001098
ISS
DmeFBgn0001098
FBgn0039071
GO:0005829 cytosol C
IDA
SpoSPCC622.12c
GO:0005886 plasma membrane C
IDA
AthAt5g07440
GO:0020011 apicoplast C
ISS
PfaPF14_0286
GO:0004352 glutamate dehydrogenase activity F
IDA
AthAt5g07440
DmeFBgn0001098
ISO
MmuMGI:95753
GO:0004353 glutamate dehydrogenase [NAD(P)+]
activity		 F
IDA
AthAt5g07440
At5g18170
DmeFBgn0001098
MmuMGI:95753
IMP
AthAt5g18170
ISS
DmeFBgn0001098
FBgn0039071
GO:0004354 glutamate dehydrogenase (NADP+)
activity		 F
IDA
PfaPF14_0164
SceS000005902
S000000058
IMP
SceS000000058
S000005902
ISS
PfaPF14_0286
SceS000000058
SpoSPCC622.12c
GO:0005507 copper ion binding F
IDA
AthAt5g07440
At5g18170
GO:0005515 protein binding F
IPI
MmuMGI:95753
GO:0005524 ATP binding F
IDA
AthAt5g07440
At5g18170
GO:0008270 zinc ion binding F
IDA
AthAt5g18170
At5g07440
GO:0016491 oxidoreductase activity F
ISS
AthAt1g51720
At5g18170
At3g03910
At5g07440
GO:0019899 enzyme binding F
ISO
MmuMGI:95753
GO:0042802 identical protein binding F
IDA
DmeFBgn0001098
GO:0050897 cobalt ion binding F
IDA
AthAt5g18170
At5g07440
GO:0000003 reproduction P
IMP
CelWBGene00014095
GO:0006116 NADH oxidation P
IDA
DmeFBgn0001098
GO:0006536 glutamate metabolic process P
IDA
DmeFBgn0001098
ISS
PfaPF14_0164
GO:0006537 glutamate biosynthetic process P
IGI
SceS000005902
S000000058
IMP
SceS000000058
ISS
SpoSPCC622.12c
GO:0006807 nitrogen compound metabolic process P
IMP
AthAt5g18170
GO:0008152 metabolic process P
IDA
MmuMGI:95753
GO:0009060 aerobic respiration P
IDA
DmeFBgn0001098
GO:0009646 response to absence of light P
IEP
AthAt5g18170
GO:0009651 response to salt stress P
IEP
AthAt5g07440
At5g18170
GO:0019551 glutamate catabolic process to
2-oxoglutarate		 P
ISS
DmeFBgn0001098
FBgn0039071
GO:0019676 ammonia assimilation cycle P
IEP
SceS000005902
S000000058
ISS
SpoSPCC622.12c
GO:0032024 positive regulation of insulin
secretion		 P
IGI
MmuMGI:95753
GO:0040007 growth P
IMP
CelWBGene00014095
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00014095
GO:0046686 response to cadmium ion P
IEP
AthAt5g07440
At5g18170
GO:0051171 regulation of nitrogen compound metabolic
process		 P
IEP
AthAt3g03910

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC622.12c
(P78804)		 YAL062W
(S000000058)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
IDA
SceS000000058
GO:0005634 nucleus C
IDA
SceS000000058
ISS
SpoSPCC622.12c
GO:0005737 cytoplasm C
ISS
SpoSPCC622.12c
GO:0005739 mitochondrion C
IDA
SceS000000058
ISS
SpoSPCC622.12c
GO:0005829 cytosol C
IDA
SpoSPCC622.12c
GO:0004354 glutamate dehydrogenase (NADP+)
activity		 F
IDA
SceS000000058
IMP
SceS000000058
ISS
SceS000000058
SpoSPCC622.12c
GO:0006537 glutamate biosynthetic process P
IGI
SceS000000058
IMP
SceS000000058
ISS
SpoSPCC622.12c
GO:0019676 ammonia assimilation cycle P
IEP
SceS000000058
ISS
SpoSPCC622.12c

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