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Search term: YAR015W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ADE1
SGD link S000000070
Alternative ID YAR015W
Description N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine
Synonyms YAR015W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2835 ACDHYP-

KOGs classification KOGs description
METABOLISM Phosphoribosylamidoimidazole-succinocarboxamide synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g05140 GI:15224475
Arabidopsis thaliana (Ath) At2g37690 GI:15224343
Arabidopsis thaliana (Ath) At3g21110 GI:15232462
Caenorhabditis elegans (Cel) CE03863
(WBGene00015116)		 GI:17531275 Q10457
Drosophila melanogaster (Dme) 7297955 GI:7297955 Q9VK80
Homo sapiens (Hsa) Hs17467936 GI:17467936
Homo sapiens (Hsa) Hs18565977_1 GI:18565977
Homo sapiens (Hsa) Hs22047775_1 GI:22047775
Homo sapiens (Hsa) Hs5453539 GI:5453539 P22234
Saccharomyces cerevisiae (Sce) YAR015w
(S000000070)		 GI:6319326
Saccharomyces cerevisiae (Sce) YOR128c
(S000005654)		 GI:6324702 P21264
Schizosaccharomyces pombe (Spo) SPBC409.10 GI:19112252 Q9UUB4
Schizosaccharomyces pombe (Spo) SPCC1322.13 GI:19075641 P15567


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000070
SpoSPBC409.10
ISS
SpoSPBC409.10
GO:0005737 cytoplasm C
IDA
SceS000005654
S000000070
ISS
SpoSPBC409.10
SPCC1322.13
GO:0005829 cytosol C
IDA
SpoSPBC409.10
SPCC1322.13
GO:0009320 phosphoribosylaminoimidazole carboxylase
complex		 C
ISS
AthAt2g05140
GO:0009507 chloroplast C
IDA
AthAt3g21110
At2g37690
GO:0004638 phosphoribosylaminoimidazole carboxylase
activity		 F
IMP
SceS000005654
ISS
AthAt2g37690
At2g05140
TAS
SpoSPCC1322.13
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide
synthase activity		 F
IDA
SceS000000070
IGI
AthAt3g21110
IMP
SceS000000070
ISS
AthAt3g21110
SpoSPBC409.10
GO:0002119 nematode larval development P
IMP
CelWBGene00015116
GO:0006144 purine base metabolic process P
IMP
SceS000005654
ISS
SpoSPCC1322.13
TAS
SceS000005654
GO:0006164 purine nucleotide biosynthetic
process		 P
IDA
SceS000000070
IGI
AthAt3g21110
IMP
SceS000000070
ISS
AthAt3g21110
TAS
SceS000005654
GO:0006189 'de novo' IMP biosynthetic process P
IDA
SceS000000070
IMP
SceS000000070
ISS
AthAt2g05140
At2g37690
SpoSPBC409.10
SPCC1322.13
TAS
SceS000005654
GO:0009555 pollen development P
IMP
AthAt2g37690
GO:0009733 response to auxin stimulus P
IDA
AthAt3g21110
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000070
GO:0040007 growth P
IMP
CelWBGene00015116
GO:0046084 adenine biosynthetic process P
IMP
SpoSPBC409.10

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38333

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) ade7
(SPBC409.10)		 GI:19112252 Q9UUB4
Saccharomyces cerevisiae (Sce) ADE1
(S000000070)		 GI:6319326
Kluyveromyces lactis (Kla) KLLA0C04235g GI:50304861
Eremothecium gossypii (Ego) AGOS_AER221W GI:45190824
Magnaporthe grisea (Mgr) MGG_12537 GI:145609750
Neurospora crassa (Ncr) NCU03166.1 GI:32420317
Arabidopsis thaliana (Ath) PUR7 GI:79313319
Oryza sativa (Osa) Os09g0467100 GI:115479657


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000070
SpoSPBC409.10
ISS
SpoSPBC409.10
GO:0005737 cytoplasm C
IDA
SceS000000070
ISS
SpoSPBC409.10
GO:0005829 cytosol C
IDA
SpoSPBC409.10
GO:0009507 chloroplast C
IDA
AthPUR7
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide
synthase activity		 F
IDA
SceS000000070
IGI
AthPUR7
IMP
SceS000000070
ISS
AthPUR7
SpoSPBC409.10
GO:0006164 purine nucleotide biosynthetic
process		 P
IDA
SceS000000070
IGI
AthPUR7
IMP
SceS000000070
ISS
AthPUR7
GO:0006189 'de novo' IMP biosynthetic process P
IDA
SceS000000070
IMP
SceS000000070
ISS
SpoSPBC409.10
GO:0009733 response to auxin stimulus P
IDA
AthPUR7
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000070
GO:0046084 adenine biosynthetic process P
IMP
SpoSPBC409.10

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5606

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2723 AER221W
Arabidopsis thaliana (Ath) ath14406 At3g21110.1
Candida glabrata (Cgl) cgl2713 CAGL0I04444g
Debaryomyces hansenii (Dha) dha1384 DEHA0B16049g
Kluyveromyces lactis (Kla) kla1385 KLLA0C04235g
Neurospora crassa (Ncr) ncr3068 NCU03166.2
Oryza sativa (Osa) osa50559 5915.m00186
Saccharomyces cerevisiae (Sce) sce93 YAR015W
(S000000070)
Schizosaccharomyces pombe (Spo) spo2934 SPBC409.10 Q9UUB4
Yarrowia lipolytica (Yli) yli5237 YALI0E33033g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000070
SpoSPBC409.10
ISS
SpoSPBC409.10
GO:0005737 cytoplasm C
IDA
SceS000000070
ISS
SpoSPBC409.10
GO:0005829 cytosol C
IDA
SpoSPBC409.10
GO:0009507 chloroplast C
IDA
AthAt3g21110
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide
synthase activity		 F
IDA
SceS000000070
IGI
AthAt3g21110
IMP
SceS000000070
ISS
AthAt3g21110
SpoSPBC409.10
GO:0006164 purine nucleotide biosynthetic
process		 P
IDA
SceS000000070
IGI
AthAt3g21110
IMP
SceS000000070
ISS
AthAt3g21110
GO:0006189 'de novo' IMP biosynthetic process P
IDA
SceS000000070
IMP
SceS000000070
ISS
SpoSPBC409.10
GO:0009733 response to auxin stimulus P
IDA
AthAt3g21110
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000070
GO:0046084 adenine biosynthetic process P
IMP
SpoSPBC409.10

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC409.10
(Q9UUB4)		 YAR015W
(S000000070)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000070
SpoSPBC409.10
ISS
SpoSPBC409.10
GO:0005737 cytoplasm C
IDA
SceS000000070
ISS
SpoSPBC409.10
GO:0005829 cytosol C
IDA
SpoSPBC409.10
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide
synthase activity		 F
IDA
SceS000000070
IMP
SceS000000070
ISS
SpoSPBC409.10
GO:0006164 purine nucleotide biosynthetic
process		 P
IDA
SceS000000070
IMP
SceS000000070
GO:0006189 'de novo' IMP biosynthetic process P
IDA
SceS000000070
IMP
SceS000000070
ISS
SpoSPBC409.10
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000070
GO:0046084 adenine biosynthetic process P
IMP
SpoSPBC409.10

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s.khadayate@ucl.ac.uk