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Search term: YBL017C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PEP1
SGD link S000000113
Alternative ID YBL017C
Description Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments
Synonyms YBL017C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3511 A--HYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Sortilin and related receptors

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g23120 GI:15237225
Homo sapiens (Hsa) Hs4507157_1
(SORL1)
GI:4507157 Q92673
Homo sapiens (Hsa) Hs17149834
(SORT1)
GI:17149834 Q99523
Homo sapiens (Hsa) Hs18379342 GI:18379342
Homo sapiens (Hsa) Hs18379344 GI:18379344
Homo sapiens (Hsa) Hs18379346
(SORCS3)
GI:18379346 Q9UPU3
Saccharomyces cerevisiae (Sce) YBL017c
(S000000113)
GI:6319454 P32319
Saccharomyces cerevisiae (Sce) YCR099c GI:6319942 P25657
Saccharomyces cerevisiae (Sce) YCR100c GI:6319943 P25606
Saccharomyces cerevisiae (Sce) YCR101c GI:6319944 P25607
Saccharomyces cerevisiae (Sce) YIL173w
(S000001435)
GI:6322020 P40438
Saccharomyces cerevisiae (Sce) YJL222w
(S000003758)
GI:6322239 P40890
Saccharomyces cerevisiae (Sce) YNR065c GI:6324393 P53751
Saccharomyces cerevisiae (Sce) YNR066c GI:6324394 P53752
Schizosaccharomyces pombe (Spo) SPBC16C6.06 GI:19113596 O42930


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003758
YCR099c
YNR065c
YCR100c
GO:0005624 membrane fraction C
IDA
SceYNR066c
YCR101c
GO:0005768 endosome C
IDA
SceS000001435
NAS
HsaSORT1
RCA
SceS000000113
GO:0005769 early endosome C
IDA
HsaSORT1
GO:0005792 microsome C
IDA
HsaSORT1
GO:0005794 Golgi apparatus C
IDA
HsaSORT1
SpoSPBC16C6.06
TAS
SceS000000113
GO:0005886 plasma membrane C
IDA
HsaSORT1
NAS
HsaSORT1
GO:0005887 integral to plasma membrane C
TAS
HsaSORL1
GO:0005905 coated pit C
IDA
HsaSORT1
GO:0009507 chloroplast C
IDA
AthAt5g23120
GO:0009533 chloroplast stromal thylakoid C
IDA
AthAt5g23120
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g23120
GO:0009543 chloroplast thylakoid lumen C
IDA
AthAt5g23120
ISS
AthAt5g23120
GO:0009570 chloroplast stroma C
IDA
AthAt5g23120
GO:0009579 thylakoid C
IDA
AthAt5g23120
GO:0009986 cell surface C
IDA
HsaSORT1
GO:0016020 membrane C
NAS
HsaSORCS3
GO:0016021 integral to membrane C
IDA
HsaSORT1
GO:0016023 cytoplasmic membrane-bounded vesicle C
IDA
HsaSORT1
GO:0030095 chloroplast photosystem II C
ISS
AthAt5g23120
GO:0030136 clathrin-coated vesicle C
IDA
HsaSORT1
GO:0031977 thylakoid lumen C
IDA
AthAt5g23120
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaSORT1
GO:0003674 molecular_function F
ND
SceYCR101c
YCR099c
YCR100c
YNR065c
YNR066c
GO:0004888 transmembrane receptor activity F
TAS
HsaSORL1
GO:0005048 signal sequence binding F
IGI
SceS000001435
S000003758
IMP
SceS000000113
IPI
SceS000000113
ISS
SceS000001435
S000003758
SpoSPBC16C6.06
GO:0005515 protein binding F
IPI
HsaSORT1
GO:0008188 neuropeptide receptor activity F
NAS
HsaSORCS3
GO:0010465 nerve growth factor receptor activity F
IDA
HsaSORT1
GO:0019899 enzyme binding F
IPI
HsaSORT1
GO:0030169 low-density lipoprotein binding F
IPI
HsaSORL1
GO:0030379 neurotensin receptor activity, non-G-protein
coupled
F
IDA
HsaSORT1
GO:0048406 nerve growth factor binding F
IPI
HsaSORT1
GO:0006461 protein complex assembly P
IMP
AthAt5g23120
GO:0006623 protein targeting to vacuole P
IMP
SceS000000113
SpoSPBC16C6.06
IPI
SceS000000113
GO:0006895 Golgi to endosome transport P
IDA
HsaSORT1
GO:0006896 Golgi to vacuole transport P
IGI
SceS000001435
S000003758
RCA
SceS000000113
GO:0006897 endocytosis P
IDA
HsaSORT1
GO:0006898 receptor-mediated endocytosis P
TAS
HsaSORL1
GO:0007034 vacuolar transport P
IMP
SceS000000113
SpoSPBC16C6.06
IPI
SceS000000113
GO:0007186 G-protein coupled receptor protein signaling
pathway
P
IMP
HsaSORT1
GO:0007218 neuropeptide signaling pathway P
IDA
HsaSORT1
NAS
HsaSORCS3
GO:0008150 biological_process P
ND
SceYCR101c
YNR066c
YCR099c
YCR100c
YNR065c
GO:0008333 endosome to lysosome transport P
IDA
HsaSORT1
GO:0008624 induction of apoptosis by extracellular
signals
P
IMP
HsaSORT1
GO:0009657 plastid organization P
IMP
AthAt5g23120
GO:0010468 regulation of gene expression P
IMP
HsaSORT1
GO:0014902 myotube differentiation P
IMP
HsaSORT1
GO:0016050 vesicle organization P
IDA
HsaSORT1
GO:0016192 vesicle-mediated transport P
RCA
SceS000000113
GO:0030433 ER-associated protein catabolic
process
P
IMP
SceS000000113
GO:0032509 endosome transport via multivesicular body sorting
pathway
P
IDA
HsaSORT1
GO:0032868 response to insulin stimulus P
IMP
HsaSORT1
GO:0043066 negative regulation of apoptosis P
IDA
HsaSORT1
GO:0045184 establishment of protein localization P
RCA
SceS000000113
GO:0046323 glucose import P
IMP
HsaSORT1
GO:0046686 response to cadmium ion P
IEP
AthAt5g23120
GO:0048011 nerve growth factor receptor signaling
pathway
P
IMP
HsaSORT1
GO:0048227 plasma membrane to endosome transport P
IDA
HsaSORT1
GO:0051005 negative regulation of lipoprotein lipase
activity
P
IDA
HsaSORT1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117723

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SORT1 GI:17149834 Q99523
Pan troglodytes (Ptr) SORT1 GI:114558219
Canis familiaris (Cfa) SORT1 GI:73959939
Mus musculus (Mmu) Sort1
(MGI:1338015)
GI:34610211 Q6PHU5
Rattus norvegicus (Rno) Sort1
(RGD:619999)
GI:109465377
Schizosaccharomyces pombe (Spo) pep1 GI:19113596
Saccharomyces cerevisiae (Sce) PEP1
(S000000113)
GI:6319454 P32319
Saccharomyces cerevisiae (Sce) VTH1
(S000001435)
GI:6322020 P40438
Saccharomyces cerevisiae (Sce) VTH2
(S000003758)
GI:6322239 P40890
Saccharomyces cerevisiae (Sce) YNR065C GI:6324393 P53751
Kluyveromyces lactis (Kla) KLLA0E10505g GI:50308841
Magnaporthe grisea (Mgr) MGG_00506 GI:145611298
Neurospora crassa (Ncr) NCU02669.1 GI:32422849