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Search term: YBL019W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name APN2
SGD link S000000115
Alternative ID YBL019W
Description Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII
Synonyms YBL019W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1294 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Apurinic/apyrimidinic endonuclease and related enzymes

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g41460 GI:15227354
Arabidopsis thaliana (Ath) At3g48420_2 GI:7487536
Arabidopsis thaliana (Ath) At3g60950_2 GI:15232998
Arabidopsis thaliana (Ath) At3g61030_2 GI:18411789
Arabidopsis thaliana (Ath) At4g36050 GI:15234289
Caenorhabditis elegans (Cel) CE16306
(WBGene00001372)		 GI:17506501
Drosophila melanogaster (Dme) 7295875_2
(FBgn0004584)		 GI:17136678 B7YZZ9
Homo sapiens (Hsa) Hs18375501 GI:18375501 P27695
Homo sapiens (Hsa) Hs18375507
(APEX2)		 GI:18375507 Q9UBZ4
Saccharomyces cerevisiae (Sce) YBL019w
(S000000115)		 GI:6319452 P38207
Schizosaccharomyces pombe (Spo) SPBC3D6.10 GI:19112314 P87175
Encephalitozoon cuniculi (Ecu) ECU06g1360 GI:19074386 Q8SRN6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g61030
At4g36050
GO:0005634 nucleus C
IC
SceS000000115
IDA
SpoSPBC3D6.10
NAS
DmeFBgn0004584
GO:0005886 plasma membrane C
IDA
AthAt3g60950
GO:0009507 chloroplast C
IDA
AthAt3g48420
GO:0009570 chloroplast stroma C
IDA
AthAt3g48420
GO:0009941 chloroplast envelope C
IDA
AthAt3g48420
GO:0042644 chloroplast nucleoid C
IDA
AthAt2g41460
GO:0003674 molecular_function F
ND
AthAt3g61030
At3g60950
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
AthAt2g41460
CelWBGene00001372
DmeFBgn0004584
SceS000000115
ISS
DmeFBgn0004584
GO:0004528 phosphodiesterase I activity F
ISS
SpoSPBC3D6.10
GO:0008081 phosphoric diester hydrolase activity F
IDA
CelWBGene00001372
SceS000000115
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000000115
IMP
SpoSPBC3D6.10
NAS
DmeFBgn0004584
GO:0008408 3'-5' exonuclease activity F
IDA
DmeFBgn0004584
GO:0016787 hydrolase activity F
ISS
AthAt3g48420
GO:0002119 nematode larval development P
IMP
CelWBGene00001372
GO:0006281 DNA repair P
IMP
CelWBGene00001372
ISS
DmeFBgn0004584
GO:0006284 base-excision repair P
IC
SpoSPBC3D6.10
IDA
CelWBGene00001372
IGI
SceS000000115
IMP
CelWBGene00001372
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0004584
GO:0008150 biological_process P
ND
AthAt3g61030
At3g60950
GO:0009790 embryo development P
IMP
CelWBGene00001372
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001372
GO:0034614 cellular response to reactive oxygen
species		 P
IMP
SpoSPBC3D6.10
GO:0040007 growth P
IMP
CelWBGene00001372
GO:0045941 positive regulation of transcription P
TAS
AthAt2g41460

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5344

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) APEX2 GI:18375507 Q9UBZ4
Canis familiaris (Cfa) APEX2 GI:74007458
Mus musculus (Mmu) Apex2
(MGI:1924872)		 GI:21541818 Q68G58
Rattus norvegicus (Rno) Apex2 GI:109499818
Schizosaccharomyces pombe (Spo) apn2
(SPBC3D6.10)		 GI:19112314 P87175
Saccharomyces cerevisiae (Sce) APN2
(S000000115)		 GI:6319452 P38207
Kluyveromyces lactis (Kla) KLLA0E10461g GI:50308837
Eremothecium gossypii (Ego) AGOS_AFR016W GI:45198534
Magnaporthe grisea (Mgr) MGG_02980 GI:39971027
Neurospora crassa (Ncr) NCU01961.1 GI:32417346
Arabidopsis thaliana (Ath) AT4G36050 GI:79610414
Oryza sativa (Osa) Os09g0536000 GI:115480379


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g36050
GO:0005634 nucleus C
IC
SceS000000115
IDA
MmuMGI:1924872
SpoSPBC3D6.10
GO:0005739 mitochondrion C
IDA
MmuMGI:1924872
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1924872
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000000115
GO:0004528 phosphodiesterase I activity F
ISS
SpoSPBC3D6.10
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000000115
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000000115
IMP
SpoSPBC3D6.10
GO:0006284 base-excision repair P
IC
SpoSPBC3D6.10
IGI
SceS000000115
GO:0034614 cellular response to reactive oxygen
species		 P
IMP
SpoSPBC3D6.10

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3206

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3208 AFR016W
Arabidopsis thaliana (Ath) ath21772 At4g36050.1
Arabidopsis thaliana (Ath) ath21773 At4g36050.2
Candida glabrata (Cgl) cgl3178 CAGL0J04356g
Cryptococcus neoformans (Cne) cne342 162.m02940
Debaryomyces hansenii (Dha) dha6257 DEHA0G12507g
Danio rerio (Dre) dre31755 ENSDARP00000021896
(zgc:55889)		 Q803D4
Encephalitozoon cuniculi (Ecu) ecu1613 19074386
Takifugu rubripes (Fru) fru15474 SINFRUP00000131313
Takifugu rubripes (Fru) fru15473 SINFRUP00000168690
Homo sapiens (Hsa) hsa32869 ENSP00000306132
Kluyveromyces lactis (Kla) kla3422 KLLA0E10461g
Mus musculus (Mmu) mmu29709 ENSMUSP00000026303
(MGI:1924872)		 A2AFM3
Neurospora crassa (Ncr) ncr1906 NCU01961.2
Oryza sativa (Osa) osa48330 5664.m00141
Oryza sativa (Osa) osa60398 6568.m00161
Plasmodium falciparum (Pfa) pfa1736 PF14_0285
Rattus norvegicus (Rno) rno31161 ENSRNOP00000000179
(RGD:1565983)
Rattus norvegicus (Rno) rno10481 ENSRNOP00000037807
(GI:289662)
Rattus norvegicus (Rno) rno31160 ENSRNOP00000039326
Rattus norvegicus (Rno) rno31162 ENSRNOP00000047607
Saccharomyces cerevisiae (Sce) sce144 YBL019W
(S000000115)
Schizosaccharomyces pombe (Spo) spo391 SPBC3D6.10 P87175
Yarrowia lipolytica (Yli) yli2018 YALI0C07436g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g36050
PfaPF14_0285
GO:0005634 nucleus C
IC
SceS000000115
IDA
MmuMGI:1924872
SpoSPBC3D6.10
GO:0005739 mitochondrion C
IDA
MmuMGI:1924872
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1924872
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000000115
GO:0004528 phosphodiesterase I activity F
ISS
SpoSPBC3D6.10
GO:0004536 deoxyribonuclease activity F
ISS
PfaPF14_0285
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000000115
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000000115
IMP
SpoSPBC3D6.10
GO:0006284 base-excision repair P
IC
SpoSPBC3D6.10
IGI
SceS000000115
GO:0034614 cellular response to reactive oxygen
species		 P
IMP
SpoSPBC3D6.10

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3D6.10
(P87175)		 YBL019W
(S000000115)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000115
IDA
SpoSPBC3D6.10
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000000115
GO:0004528 phosphodiesterase I activity F
ISS
SpoSPBC3D6.10
GO:0008081 phosphoric diester hydrolase activity F
IDA
SceS000000115
GO:0008311 double-stranded DNA specific 3'-5'
exodeoxyribonuclease activity		 F
IDA
SceS000000115
IMP
SpoSPBC3D6.10
GO:0006284 base-excision repair P
IC
SpoSPBC3D6.10
IGI
SceS000000115
GO:0034614 cellular response to reactive oxygen
species		 P
IMP
SpoSPBC3D6.10

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GO info in one table:

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