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Search term: YBL023C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MCM2
SGD link S000000119
Alternative ID YBL023C
Description Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
Synonyms YBL023C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0477 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA replication licensing factor, MCM2 component

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g44900 GI:15219474
Arabidopsis thaliana (Ath) At2g14050 GI:15225568
Caenorhabditis elegans (Cel) CE19038
(WBGene00003154)		 GI:17535265
Drosophila melanogaster (Dme) 7299005
(FBgn0014861)		 GI:17137132
Homo sapiens (Hsa) Hs20535929 GI:20535929
Homo sapiens (Hsa) Hs22056246 GI:22056246
Homo sapiens (Hsa) Hs4758706 GI:4758706
Saccharomyces cerevisiae (Sce) YBL023c
(S000000119)		 GI:6319448 P29469
Schizosaccharomyces pombe (Spo) SPBC4.04c GI:19112269 P40377
Encephalitozoon cuniculi (Ecu) ECU04g0850 GI:19074162 Q8SS42
Arabidopsis thaliana (Ath) At1g44900 GI:15219474
Arabidopsis thaliana (Ath) At2g14050 GI:15225568
Caenorhabditis elegans (Cel) CE19038
(WBGene00003154)		 GI:17535265
Drosophila melanogaster (Dme) 7299005
(FBgn0014861)		 GI:17137132
Homo sapiens (Hsa) Hs20535929 GI:20535929
Homo sapiens (Hsa) Hs22056246 GI:22056246
Homo sapiens (Hsa) Hs4758706 GI:4758706
Saccharomyces cerevisiae (Sce) YBL023c
(S000000119)		 GI:6319448 P29469
Schizosaccharomyces pombe (Spo) SPBC4.04c GI:19112269 P40377
Encephalitozoon cuniculi (Ecu) ECU04g0850 GI:19074162 Q8SS42
Arabidopsis thaliana (Ath) At1g44900 GI:15219474
Arabidopsis thaliana (Ath) At2g14050 GI:15225568
Caenorhabditis elegans (Cel) CE19038
(WBGene00003154)		 GI:17535265
Drosophila melanogaster (Dme) 7299005
(FBgn0014861)		 GI:17137132
Homo sapiens (Hsa) Hs20535929 GI:20535929
Homo sapiens (Hsa) Hs22056246 GI:22056246
Homo sapiens (Hsa) Hs4758706 GI:4758706
Saccharomyces cerevisiae (Sce) YBL023c
(S000000119)		 GI:6319448 P29469
Schizosaccharomyces pombe (Spo) SPBC4.04c GI:19112269 P40377
Encephalitozoon cuniculi (Ecu) ECU04g0850 GI:19074162 Q8SS42


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g14050
GO:0005634 nucleus C
IDA
SceS000000119
SpoSPBC4.04c
NAS
DmeFBgn0014861
GO:0005656 pre-replicative complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0005657 replication fork C
NAS
SpoSPBC4.04c
GO:0005737 cytoplasm C
IDA
SceS000000119
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
GO:0031298 replication fork protection complex C
IDA
SceS000000119
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPBC4.04c
GO:0042555 MCM complex C
IDA
SceS000000119
SpoSPBC4.04c
GO:0003677 DNA binding F
ISS
AthAt1g44900
At2g14050
NAS
DmeFBgn0014861
GO:0003678 DNA helicase activity F
RCA
SceS000000119
GO:0003682 chromatin binding F
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0003688 DNA replication origin binding F
IDA
SceS000000119
GO:0003697 single-stranded DNA binding F
IMP
SceS000000119
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000119
TAS
SpoSPBC4.04c
GO:0004386 helicase activity F
RCA
SceS000000119
GO:0005524 ATP binding F
ISS
AthAt1g44900
At2g14050
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000119
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt2g14050
At1g44900
RCA
SceS000000119
GO:0016887 ATPase activity F
RCA
SceS000000119
GO:0042623 ATPase activity, coupled F
RCA
SceS000000119
GO:0043138 3'-5' DNA helicase activity F
IDA
DmeFBgn0014861
RCA
SceS000000119
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000119
GO:0000003 reproduction P
IMP
CelWBGene00003154
GO:0000084 S phase of mitotic cell cycle P
IMP
SceS000000119
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000119
GO:0002119 nematode larval development P
IMP
CelWBGene00003154
GO:0006260 DNA replication P
NAS
DmeFBgn0014861
TAS
DmeFBgn0014861
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000119
IPI
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0006268 DNA unwinding involved in replication P
TAS
AthAt1g44900
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPBC4.04c
ISS
AthAt2g14050
At1g44900
RCA
SceS000000119
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000119
TAS
SpoSPBC4.04c
GO:0006461 protein complex assembly P
RCA
SceS000000119
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPBC4.04c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC4.04c
GO:0008283 cell proliferation P
NAS
DmeFBgn0014861
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003154
GO:0009790 embryo development P
IMP
AthAt1g44900
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003154
GO:0010082 regulation of root meristem growth P
IMP
AthAt1g44900
GO:0030261 chromosome condensation P
IMP
DmeFBgn0014861
GO:0040007 growth P
IMP
CelWBGene00003154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003154
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003154
GO:0042127 regulation of cell proliferation P
IMP
AthAt1g44900
GO:0048364 root development P
IMP
AthAt1g44900

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3325

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MCM2 GI:33356547
Pan troglodytes (Ptr) MCM2 GI:114589012
Canis familiaris (Cfa) MCM2 GI:73984933
Mus musculus (Mmu) Mcm2
(MGI:105380)		 GI:6678826 P97310
Rattus norvegicus (Rno) Mcm2 GI:62647780
Gallus gallus (Gga) MCM2 GI:57524951
Drosophila melanogaster (Dme) Mcm2
(FBgn0014861)		 GI:17137132
Anopheles gambiae (Aga) AgaP_AGAP004275 GI:158291683
Caenorhabditis elegans (Cel) mcm-2
(CE19038;
WBGene00003154)		 GI:71997752
Schizosaccharomyces pombe (Spo) cdc19 GI:19112269
Saccharomyces cerevisiae (Sce) MCM2
(S000000119)		 GI:6319448 P29469
Kluyveromyces lactis (Kla) KLLA0F12584g GI:50311249
Eremothecium gossypii (Ego) AGOS_AFR178W GI:45198696
Magnaporthe grisea (Mgr) MGG_08122 GI:39946004
Neurospora crassa (Ncr) NCU04327.1 GI:32406108
Arabidopsis thaliana (Ath) AT1G44900 GI:145336465
Oryza sativa (Osa) Os11g0484300 GI:115485533
Plasmodium falciparum (Pfa) PF14_0177 GI:124808572


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
TAS
HsaMCM2
GO:0005634 nucleus C
IDA
MmuMGI:105380
SceS000000119
NAS
DmeFBgn0014861
GO:0005654 nucleoplasm C
EXP
HsaMCM2
GO:0005656 pre-replicative complex C
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0005664 nuclear origin of replication recognition
complex		 C
IDA
MmuMGI:105380
GO:0005737 cytoplasm C
IDA
SceS000000119
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000000119
GO:0031298 replication fork protection complex C
IDA
SceS000000119
GO:0042555 MCM complex C
IDA
SceS000000119
GO:0003677 DNA binding F
ISS
AthAt1g44900
NAS
DmeFBgn0014861
GO:0003678 DNA helicase activity F
RCA
SceS000000119
GO:0003682 chromatin binding F
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0003688 DNA replication origin binding F
IDA
MmuMGI:105380
SceS000000119
GO:0003697 single-stranded DNA binding F
IMP
SceS000000119
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000119
GO:0004386 helicase activity F
RCA
SceS000000119
GO:0005515 protein binding F
IPI
HsaMCM2
MmuMGI:105380
GO:0005524 ATP binding F
ISS
AthAt1g44900
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000119
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt1g44900
RCA
SceS000000119
GO:0016887 ATPase activity F
RCA
SceS000000119
GO:0042623 ATPase activity, coupled F
RCA
SceS000000119
GO:0043138 3'-5' DNA helicase activity F
IDA
DmeFBgn0014861
RCA
SceS000000119
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000119
GO:0000003 reproduction P
IMP
CelWBGene00003154
GO:0000084 S phase of mitotic cell cycle P
IMP
SceS000000119
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000119
GO:0002119 nematode larval development P
IMP
CelWBGene00003154
GO:0006260 DNA replication P
EXP
HsaMCM2
NAS
DmeFBgn0014861
TAS
DmeFBgn0014861
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000119
IPI
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0006268 DNA unwinding involved in replication P
IDA
MmuMGI:105380
TAS
AthAt1g44900
GO:0006270 DNA-dependent DNA replication initiation P
ISS
AthAt1g44900
RCA
SceS000000119
TAS
MmuMGI:105380
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000119
GO:0006334 nucleosome assembly P
IDA
MmuMGI:105380
GO:0006461 protein complex assembly P
RCA
SceS000000119
GO:0008283 cell proliferation P
NAS
DmeFBgn0014861
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003154
GO:0009790 embryo development P
IMP
AthAt1g44900
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003154
GO:0010082 regulation of root meristem growth P
IMP
AthAt1g44900
GO:0030261 chromosome condensation P
IMP
DmeFBgn0014861
GO:0040007 growth P
IMP
CelWBGene00003154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003154
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003154
GO:0042127 regulation of cell proliferation P
IMP
AthAt1g44900
GO:0048364 root development P
IMP
AthAt1g44900
GO:0051726 regulation of cell cycle P
ISS
PfaPF14_0177

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1910

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6809 ENSANGP00000013357
Ashbya gossypii (Ago) ago3370 AFR178W
Arabidopsis thaliana (Ath) ath3922 At1g44900.1
Caenorhabditis elegans (Cel) cel17875 Y17G7B.5a
(CE19038;
WBGene00003154)
Candida glabrata (Cgl) cgl3182 CAGL0J04444g
Cryptococcus neoformans (Cne) cne4324 177.m03079
Dictyostelium discoideum (Ddi) ddi7153 DDB0187054
Debaryomyces hansenii (Dha) dha5406 DEHA0F22861
Drosophila melanogaster (Dme) dme11482 CG7538-PA
(FBgn0014861)
Danio rerio (Dre) dre27461 ENSDARP00000011796
(mcm2)		 Q8JGR5
Danio rerio (Dre) dre27460 ENSDARP00000049625
(mcm2)		 Q7ZUR0
Encephalitozoon cuniculi (Ecu) ecu800 19074162
Takifugu rubripes (Fru) fru5009 SINFRUP00000163970
Takifugu rubripes (Fru) fru5010 SINFRUP00000163974
Gallus gallus (Gga) gga5261 ENSGALP00000009709
(MCM2)		 Q5ZLZ1
Homo sapiens (Hsa) hsa23083 ENSP00000265056
(MCM2)		 P49736
Kluyveromyces lactis (Kla) kla4649 KLLA0F12584g
Mus musculus (Mmu) mmu22314 ENSMUSP00000061923
(MGI:105380)		 Q3UJN1
Neurospora crassa (Ncr) ncr4203 NCU04327.2
Oryza sativa (Osa) osa74168 7168.m00148
Plasmodium falciparum (Pfa) pfa1540 PF14_0177
Rattus norvegicus (Rno) rno21824 ENSRNOP00000022231
(RGD:1305577)
Saccharomyces cerevisiae (Sce) sce148 YBL023C
(S000000119)
Schizosaccharomyces pombe (Spo) spo458 SPBC4.04c P40377
Yarrowia lipolytica (Yli) yli5537 YALI0F04664g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
MmuMGI:105380
SceS000000119
SpoSPBC4.04c
NAS
DmeFBgn0014861
GO:0005656 pre-replicative complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0005657 replication fork C
NAS
SpoSPBC4.04c
GO:0005664 nuclear origin of replication recognition
complex		 C
IDA
MmuMGI:105380
GO:0005737 cytoplasm C
IDA
SceS000000119
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
GO:0031298 replication fork protection complex C
IDA
SceS000000119
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPBC4.04c
GO:0042555 MCM complex C
IDA
SceS000000119
SpoSPBC4.04c
GO:0003677 DNA binding F
ISS
AthAt1g44900
NAS
DmeFBgn0014861
GO:0003678 DNA helicase activity F
RCA
SceS000000119
GO:0003682 chromatin binding F
IDA
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0003688 DNA replication origin binding F
IDA
MmuMGI:105380
SceS000000119
GO:0003697 single-stranded DNA binding F
IMP
SceS000000119
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000119
TAS
SpoSPBC4.04c
GO:0004386 helicase activity F
RCA
SceS000000119
GO:0005515 protein binding F
IPI
MmuMGI:105380
GO:0005524 ATP binding F
ISS
AthAt1g44900
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000119
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt1g44900
RCA
SceS000000119
GO:0016887 ATPase activity F
RCA
SceS000000119
GO:0042623 ATPase activity, coupled F
RCA
SceS000000119
GO:0043138 3'-5' DNA helicase activity F
IDA
DmeFBgn0014861
RCA
SceS000000119
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000119
GO:0000003 reproduction P
IMP
CelWBGene00003154
GO:0000084 S phase of mitotic cell cycle P
IMP
SceS000000119
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000119
GO:0002119 nematode larval development P
IMP
CelWBGene00003154
GO:0006260 DNA replication P
NAS
DmeFBgn0014861
TAS
DmeFBgn0014861
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000119
IPI
SceS000000119
ISS
DmeFBgn0014861
NAS
DmeFBgn0014861
GO:0006268 DNA unwinding involved in replication P
IDA
MmuMGI:105380
TAS
AthAt1g44900
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPBC4.04c
ISS
AthAt1g44900
RCA
SceS000000119
TAS
MmuMGI:105380
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000119
TAS
SpoSPBC4.04c
GO:0006334 nucleosome assembly P
IDA
MmuMGI:105380
GO:0006461 protein complex assembly P
RCA
SceS000000119
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPBC4.04c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC4.04c
GO:0008283 cell proliferation P
NAS
DmeFBgn0014861
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00003154
GO:0009790 embryo development P
IMP
AthAt1g44900
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003154
GO:0010082 regulation of root meristem growth P
IMP
AthAt1g44900
GO:0030261 chromosome condensation P
IMP
DmeFBgn0014861
GO:0040007 growth P
IMP
CelWBGene00003154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003154
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003154
GO:0042127 regulation of cell proliferation P
IMP
AthAt1g44900
GO:0048364 root development P
IMP
AthAt1g44900
GO:0051726 regulation of cell cycle P
ISS
PfaPF14_0177

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC4.04c
(P40377)		 YBL023C
(S000000119)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000119
SpoSPBC4.04c
GO:0005656 pre-replicative complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
GO:0005657 replication fork C
NAS
SpoSPBC4.04c
GO:0005737 cytoplasm C
IDA
SceS000000119
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC4.04c
IDA
SceS000000119
GO:0031298 replication fork protection complex C
IDA
SceS000000119
GO:0031390 Ctf18 RFC-like complex C
IC
SpoSPBC4.04c
GO:0042555 MCM complex C
IDA
SceS000000119
SpoSPBC4.04c
GO:0003678 DNA helicase activity F
RCA
SceS000000119
GO:0003682 chromatin binding F
IDA
SceS000000119
GO:0003688 DNA replication origin binding F
IDA
SceS000000119
GO:0003697 single-stranded DNA binding F
IMP
SceS000000119
GO:0004003 ATP-dependent DNA helicase activity F
RCA
SceS000000119
TAS
SpoSPBC4.04c
GO:0004386 helicase activity F
RCA
SceS000000119
GO:0008026 ATP-dependent helicase activity F
RCA
SceS000000119
GO:0008094 DNA-dependent ATPase activity F
RCA
SceS000000119
GO:0016887 ATPase activity F
RCA
SceS000000119
GO:0042623 ATPase activity, coupled F
RCA
SceS000000119
GO:0043138 3'-5' DNA helicase activity F
RCA
SceS000000119
GO:0070035 purine NTP-dependent helicase activity F
RCA
SceS000000119
GO:0000084 S phase of mitotic cell cycle P
IMP
SceS000000119
GO:0000727 double-strand break repair via break-induced
replication		 P
IMP
SceS000000119
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000119
IPI
SceS000000119
GO:0006270 DNA-dependent DNA replication initiation P
IDA
SpoSPBC4.04c
RCA
SceS000000119
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000000119
TAS
SpoSPBC4.04c
GO:0006461 protein complex assembly P
RCA
SceS000000119
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPBC4.04c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC4.04c

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GO info in one table:

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