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Search term: YBL024W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NCL1
SGD link S000000120
Alternative ID YBL024W
Description S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120
Synonyms YBL024W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2198 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING tRNA cytosine-5-methylases and related enzymes of the NOL1/NOP2/sun superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g22400 GI:15227198
Arabidopsis thaliana (Ath) At4g40000 GI:15236100
Arabidopsis thaliana (Ath) At5g66180 GI:15239280
Caenorhabditis elegans (Cel) CE22185 GI:17510159
Caenorhabditis elegans (Cel) CE27273 GI:17510161
Caenorhabditis elegans (Cel) CE28981
(WBGene00021476)		 GI:17509941 Q95XR2
Drosophila melanogaster (Dme) 7290467 GI:7290467
Drosophila melanogaster (Dme) 7296118
(FBgn0031308)		 GI:19920494
Homo sapiens (Hsa) Hs8923285 GI:8923285
Homo sapiens (Hsa) Hs22044418 GI:22044418
Homo sapiens (Hsa) Hs11545785
(NSUN3)		 GI:11545785 Q9H649
Saccharomyces cerevisiae (Sce) YBL024w
(S000000120)		 GI:6319447 P38205
Schizosaccharomyces pombe (Spo) SPAC17D4.04 GI:19115607 Q9HGQ2
Schizosaccharomyces pombe (Spo) SPAC23C4.17 GI:19114101 O13935
Encephalitozoon cuniculi (Ecu) ECU08g0400 GI:19173366 Q8SRE3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g66180
At4g40000
At2g22400
GO:0005634 nucleus C
IDA
SceS000000120
SpoSPAC23C4.17
SPAC17D4.04
ISS
SpoSPAC17D4.04
SPAC23C4.17
GO:0005829 cytosol C
IDA
SpoSPAC17D4.04
GO:0003674 molecular_function F
ND
AthAt4g40000
GO:0016428 tRNA (cytosine-5-)-methyltransferase
activity		 F
IDA
SceS000000120
ISS
SpoSPAC23C4.17
SPAC17D4.04
GO:0008150 biological_process P
ND
AthAt4g40000
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000120
GO:0030488 tRNA methylation P
IDA
SceS000000120
ISS
SpoSPAC17D4.04
SPAC23C4.17

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
9817

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NSUN2 GI:39995082
Pan troglodytes (Ptr) NSUN2 GI:114598922
Canis familiaris (Cfa) NSUN2 GI:74003041
Mus musculus (Mmu) Nsun2
(MGI:107252)		 GI:31542461 Q1HFZ0
Rattus norvegicus (Rno) Nsun2 GI:109504531
Gallus gallus (Gga) NSUN2 GI:71896598
Drosophila melanogaster (Dme) CG6133
(FBgn0026079)		 GI:21355201
Anopheles gambiae (Aga) AgaP_AGAP002504 GI:118782687
Caenorhabditis elegans (Cel) Y48G8AL.5
(CE30462;
WBGene00021686)		 GI:25143471
Schizosaccharomyces pombe (Spo) SPAC23C4.17 GI:19114101 O13935
Schizosaccharomyces pombe (Spo) SPAC17D4.04 GI:63054645 Q9HGQ2
Saccharomyces cerevisiae (Sce) NCL1
(S000000120)		 GI:6319447 P38205
Kluyveromyces lactis (Kla) KLLA0F12562g GI:50311247
Eremothecium gossypii (Ego) AGOS_AFR179C GI:45198697
Magnaporthe grisea (Mgr) MGG_13217 GI:145603390
Neurospora crassa (Ncr) NCU05301.1 GI:32408353
Arabidopsis thaliana (Ath) AT2G22400 GI:30681697
Arabidopsis thaliana (Ath) AT4G40000 GI:42567548
Oryza sativa (Osa) Os09g0471900 GI:115479703
Oryza sativa (Osa) Os08g0484400 GI:115476970


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g40000
At2g22400
MmuMGI:107252
GO:0005634 nucleus C
IDA
SceS000000120
SpoSPAC23C4.17
SPAC17D4.04
ISS
SpoSPAC17D4.04
SPAC23C4.17
GO:0005730 nucleolus C
IDA
HsaNSUN2
GO:0005737 cytoplasm C
IDA
HsaNSUN2
GO:0005829 cytosol C
IDA
SpoSPAC17D4.04
GO:0003674 molecular_function F
ND
AthAt4g40000
MmuMGI:107252
GO:0003886 DNA (cytosine-5-)-methyltransferase
activity		 F
ISS
DmeFBgn0026079
GO:0016428 tRNA (cytosine-5-)-methyltransferase
activity		 F
IDA
HsaNSUN2
SceS000000120
ISS
SpoSPAC23C4.17
SPAC17D4.04
GO:0000003 reproduction P
IMP
CelWBGene00021686
GO:0008150 biological_process P
ND
AthAt4g40000
MmuMGI:107252
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000120
GO:0030488 tRNA methylation P
IDA
HsaNSUN2
SceS000000120
ISS
SpoSPAC17D4.04
SPAC23C4.17

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1432

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4700 ENSANGP00000022091
Ashbya gossypii (Ago) ago3371 AFR179C
Arabidopsis thaliana (Ath) ath9133 At2g22400.1
Arabidopsis thaliana (Ath) ath22219 At4g40000.1
Caenorhabditis elegans (Cel) cel19306 Y48G8AL.5
(CE30462;
WBGene00021686)
Candida glabrata (Cgl) cgl3607 CAGL0K01991g
Cryptococcus neoformans (Cne) cne735 163.m03775
Debaryomyces hansenii (Dha) dha5400 DEHA0F22748g
Drosophila melanogaster (Dme) dme16443 CG6133-PA
(FBgn0026079)
Danio rerio (Dre) dre10088 ENSDARP00000016300
Encephalitozoon cuniculi (Ecu) ecu197 19173366
Takifugu rubripes (Fru) fru37 SINFRUP00000149651
Gallus gallus (Gga) gga10669 ENSGALP00000021294
(NSUN2)		 Q5ZLV4
Gallus gallus (Gga) gga10670 ENSGALP00000021295
Homo sapiens (Hsa) hsa25019 ENSP00000264670
(NSUN2)		 Q08J23
Homo sapiens (Hsa) hsa25018 ENSP00000349180
Kluyveromyces lactis (Kla) kla4648 KLLA0F12562g
Mus musculus (Mmu) mmu7220 ENSMUSP00000022087
(MGI:107252)		 Q1HFZ0-2
Neurospora crassa (Ncr) ncr5146 NCU05301.2
Oryza sativa (Osa) osa45415 5680.m00132
Plasmodium falciparum (Pfa) pfa2345 PF07_0015
Rattus norvegicus (Rno) rno12832 ENSRNOP00000023641
(RGD:1311954)
Saccharomyces cerevisiae (Sce) sce149 YBL024W
(S000000120)
Schizosaccharomyces pombe (Spo) spo2468 SPAC17D4.04 Q9HGQ2
Schizosaccharomyces pombe (Spo) spo733 SPAC23C4.17 O13935
Yarrowia lipolytica (Yli) yli4146 YALI0E06765g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g40000
At2g22400
MmuMGI:107252
GO:0005634 nucleus C
IDA
SceS000000120
SpoSPAC23C4.17
SPAC17D4.04
ISS
SpoSPAC17D4.04
SPAC23C4.17
GO:0005829 cytosol C
IDA
SpoSPAC17D4.04
GO:0003674 molecular_function F
ND
AthAt4g40000
MmuMGI:107252
GO:0003886 DNA (cytosine-5-)-methyltransferase
activity		 F
ISS
DmeFBgn0026079
GO:0016428 tRNA (cytosine-5-)-methyltransferase
activity		 F
IDA
SceS000000120
ISS
SpoSPAC23C4.17
SPAC17D4.04
GO:0000003 reproduction P
IMP
CelWBGene00021686
GO:0008150 biological_process P
ND
AthAt4g40000
MmuMGI:107252
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000120
GO:0030488 tRNA methylation P
IDA
SceS000000120
ISS
SpoSPAC17D4.04
SPAC23C4.17

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C4.17
(O13935)		 YBL024W
(S000000120)
SPAC17D4.04
(Q9HGQ2)		 YBL024W
(S000000120)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000120
SpoSPAC23C4.17
SPAC17D4.04
ISS
SpoSPAC17D4.04
SPAC23C4.17
GO:0005829 cytosol C
IDA
SpoSPAC17D4.04
GO:0016428 tRNA (cytosine-5-)-methyltransferase
activity		 F
IDA
SceS000000120
ISS
SpoSPAC23C4.17
SPAC17D4.04
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000120
GO:0030488 tRNA methylation P
IDA
SceS000000120
ISS
SpoSPAC17D4.04
SPAC23C4.17

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