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Search term: YBL050W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC17
SGD link S000000146
Alternative ID YBL050W
Description Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP
Synonyms YBL050W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1586 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Protein required for fusion of vesicles in vesicular transport, alpha-SNAP

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g56190 GI:15228848
Arabidopsis thaliana (Ath) At3g56450 GI:15228924
Caenorhabditis elegans (Cel) CE27369_2 GI:17559082
Drosophila melanogaster (Dme) 7293665
(FBgn0011712)		 GI:17737681
Homo sapiens (Hsa) Hs4505329 GI:4505329
Homo sapiens (Hsa) Hs17484764 GI:17484764
Saccharomyces cerevisiae (Sce) YBL050w
(S000000146)		 GI:6319421 P32602
Schizosaccharomyces pombe (Spo) SPAC959.02 GI:19115081 Q9P4X4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000000146
GO:0005773 vacuole C
IDA
AthAt3g56190
GO:0005829 cytosol C
IDA
SceS000000146
GO:0005886 plasma membrane C
IDA
AthAt3g56450
At3g56190
GO:0016020 membrane C
IDA
AthAt3g56190
GO:0031201 SNARE complex C
IC
SpoSPAC959.02
IPI
SceS000000146
GO:0001671 ATPase activator activity F
IDA
SceS000000146
GO:0005483 soluble NSF attachment protein
activity		 F
IDA
SceS000000146
IPI
SceS000000146
ISS
AthAt3g56450
At3g56190
SpoSPAC959.02
GO:0006886 intracellular protein transport P
IC
SpoSPAC959.02
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPAC959.02
GO:0006914 autophagy P
IMP
SceS000000146
GO:0006944 cellular membrane fusion P
RCA
SceS000000146
GO:0016050 vesicle organization P
RCA
SceS000000146
GO:0035494 SNARE complex disassembly P
IDA
SceS000000146
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000146
ISS
SpoSPAC959.02
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000146
GO:0048284 organelle fusion P
RCA
SceS000000146
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC959.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2839

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NAPA GI:47933379
Pan troglodytes (Ptr) NAPA GI:114678093
Canis familiaris (Cfa) NAPA GI:73947208
Mus musculus (Mmu) Napa
(MGI:104563)		 GI:13385392 Q9CXX1
Rattus norvegicus (Rno) Napa
(RGD:620855)		 GI:18034791
Drosophila melanogaster (Dme) Snap
(FBgn0011712)		 GI:17737681
Anopheles gambiae (Aga) AgaP_AGAP003192 GI:58383926
Caenorhabditis elegans (Cel) snap-1
(CE38494;
WBGene00017016)		 GI:71987886
Schizosaccharomyces pombe (Spo) sec17
(SPAC959.02)		 GI:19115081 Q9P4X4
Saccharomyces cerevisiae (Sce) SEC17
(S000000146)		 GI:6319421 P32602
Kluyveromyces lactis (Kla) KLLA0E05874g GI:50308423
Eremothecium gossypii (Ego) AGOS_ABR155C GI:45185386
Magnaporthe grisea (Mgr) MGG_01121 GI:39973465
Neurospora crassa (Ncr) NCU01674.1 GI:32415267
Plasmodium falciparum (Pfa) PFE0445c GI:124506101


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000000146
GO:0005829 cytosol C
IDA
SceS000000146
GO:0031201 SNARE complex C
IC
SpoSPAC959.02
IPI
SceS000000146
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a
complex		 C
ISO
MmuMGI:104563
GO:0000149 SNARE binding F
ISO
MmuMGI:104563
GO:0001671 ATPase activator activity F
IDA
SceS000000146
GO:0005215 transporter activity F
ISS
PfaPFE0445c
GO:0005483 soluble NSF attachment protein
activity		 F
IDA
SceS000000146
IPI
SceS000000146
ISS
PfaPFE0445c
SpoSPAC959.02
GO:0005515 protein binding F
IPI
HsaNAPA
GO:0019905 syntaxin binding F
IDA
MmuMGI:104563
GO:0000003 reproduction P
IMP
CelWBGene00017016
GO:0002119 nematode larval development P
IMP
CelWBGene00017016
GO:0006886 intracellular protein transport P
IC
SpoSPAC959.02
IMP
MmuMGI:104563
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPAC959.02
GO:0006891 intra-Golgi vesicle-mediated transport P
TAS
HsaNAPA
GO:0006892 post-Golgi vesicle-mediated transport P
EXP
HsaNAPA
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00017016
GO:0006914 autophagy P
IMP
SceS000000146
GO:0006944 cellular membrane fusion P
RCA
SceS000000146
TAS
HsaNAPA
GO:0007420 brain development P
IMP
MmuMGI:104563
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017016
GO:0016044 cellular membrane organization P
EXP
HsaNAPA
GO:0016050 vesicle organization P
RCA
SceS000000146
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00017016
GO:0030182 neuron differentiation P
IMP
MmuMGI:104563
GO:0032940 secretion by cell P
IMP
CelWBGene00017016
GO:0035494 SNARE complex disassembly P
IDA
SceS000000146
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017016
GO:0040011 locomotion P
IMP
CelWBGene00017016
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000146
ISS
SpoSPAC959.02
GO:0045176 apical protein localization P
IMP
MmuMGI:104563
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000146
GO:0048284 organelle fusion P
RCA
SceS000000146
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC959.02

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_446

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5366 ENSANGP00000003165
Anopheles gambiae (Aga) aga5485 ENSANGP00000014748
Ashbya gossypii (Ago) ago748 ABR155C
Arabidopsis thaliana (Ath) ath17009 At3g56190.1
Caenorhabditis elegans (Cel) cel4945 D1014.3
(CE38494;
WBGene00017016)
Caenorhabditis elegans (Cel) cel20663 Y71H2B.5
(CE42487;
WBGene00022195)
Candida glabrata (Cgl) cgl1432 CAGL0F04653g
Cryptococcus neoformans (Cne) cne235 162.m02707
Dictyostelium discoideum (Ddi) ddi8231 DDB0188699
Dictyostelium discoideum (Ddi) ddi13210 DDB0231538
Debaryomyces hansenii (Dha) dha1701 DEHA0C06061g
Drosophila melanogaster (Dme) dme10377 CG6625-PA
(FBgn0011712)
Danio rerio (Dre) dre9570 ENSDARP00000009285
(napa)		 Q7T2F5
Danio rerio (Dre) dre18031 ENSDARP00000024741
Escherichia coli (Eco) eco1307 16129305
Takifugu rubripes (Fru) fru30354 SINFRUP00000150397
Takifugu rubripes (Fru) fru30353 SINFRUP00000150398
Takifugu rubripes (Fru) fru28894 SINFRUP00000151995
Takifugu rubripes (Fru) fru28895 SINFRUP00000170773
Takifugu rubripes (Fru) fru8039 SINFRUP00000175199
Gallus gallus (Gga) gga14336 ENSGALP00000013516
(NAPB)
Homo sapiens (Hsa) hsa19928 ENSP00000246011
Homo sapiens (Hsa) hsa16713 ENSP00000263354
(NAPA)		 P54920
Kluyveromyces lactis (Kla) kla3212 KLLA0E05874g
Mus musculus (Mmu) mmu23184 ENSMUSP00000006181
(MGI:104563)		 Q9DB05
Mus musculus (Mmu) mmu15664 ENSMUSP00000028926
(MGI:104562)		 P28663
Neurospora crassa (Ncr) ncr1628 NCU01674.2
Oryza sativa (Osa) osa8739 2683.m00158
Oryza sativa (Osa) osa12416 2824.m00168
Oryza sativa (Osa) osa36114 4924.m00103
Oryza sativa (Osa) osa36168 4925.m00048
Oryza sativa (Osa) osa67027 6943.m00081
Oryza sativa (Osa) osa68784 7027.m00139
Oryza sativa (Osa) osa78591 7383.m00120
Oryza sativa (Osa) osa78844 7503.m00154
Plasmodium falciparum (Pfa) pfa3540 PFE0445c
Rattus norvegicus (Rno) rno1103 ENSRNOP00000002044
(RGD:620855)		 P54921
Rattus norvegicus (Rno) rno19890 ENSRNOP00000006329
(RGD:1589649)		 P85969
Saccharomyces cerevisiae (Sce) sce178 YBL050W
(S000000146)
Schizosaccharomyces pombe (Spo) spo3796 SPAC959.02 Q9P4X4
Yarrowia lipolytica (Yli) yli2685 YALI0C23947g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000000146
GO:0005575 cellular_component C
ND
MmuMGI:104562
GO:0005773 vacuole C
IDA
AthAt3g56190
GO:0005829 cytosol C
IDA
SceS000000146
GO:0005886 plasma membrane C
IDA
AthAt3g56190
GO:0016020 membrane C
IDA
AthAt3g56190
GO:0031201 SNARE complex C
IC
SpoSPAC959.02
IPI
SceS000000146
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a
complex		 C
ISO
MmuMGI:104563
GO:0000149 SNARE binding F
ISO
MmuMGI:104563
GO:0001671 ATPase activator activity F
IDA
SceS000000146
GO:0005215 transporter activity F
ISS
PfaPFE0445c
GO:0005483 soluble NSF attachment protein
activity		 F
IDA
SceS000000146
IPI
SceS000000146
ISS
AthAt3g56190
PfaPFE0445c
SpoSPAC959.02
GO:0019905 syntaxin binding F
IDA
MmuMGI:104563
MGI:104562
GO:0000003 reproduction P
IMP
CelWBGene00017016
GO:0002119 nematode larval development P
IMP
CelWBGene00017016
GO:0006886 intracellular protein transport P
IC
SpoSPAC959.02
IMP
MmuMGI:104563
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPAC959.02
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00017016
GO:0006914 autophagy P
IMP
SceS000000146
GO:0006944 cellular membrane fusion P
RCA
SceS000000146
GO:0007420 brain development P
IMP
MmuMGI:104563
GO:0008150 biological_process P
ND
MmuMGI:104562
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017016
GO:0016050 vesicle organization P
RCA
SceS000000146
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00017016
GO:0030182 neuron differentiation P
IMP
MmuMGI:104563
GO:0032940 secretion by cell P
IMP
CelWBGene00017016
GO:0035494 SNARE complex disassembly P
IDA
SceS000000146
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017016
GO:0040011 locomotion P
IMP
CelWBGene00017016
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000146
ISS
SpoSPAC959.02
GO:0045176 apical protein localization P
IMP
MmuMGI:104563
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000146
GO:0048284 organelle fusion P
RCA
SceS000000146
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC959.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC959.02
(Q9P4X4)		 YBL050W
(S000000146)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000000146
GO:0005829 cytosol C
IDA
SceS000000146
GO:0031201 SNARE complex C
IC
SpoSPAC959.02
IPI
SceS000000146
GO:0001671 ATPase activator activity F
IDA
SceS000000146
GO:0005483 soluble NSF attachment protein
activity		 F
IDA
SceS000000146
IPI
SceS000000146
ISS
SpoSPAC959.02
GO:0006886 intracellular protein transport P
IC
SpoSPAC959.02
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPAC959.02
GO:0006914 autophagy P
IMP
SceS000000146
GO:0006944 cellular membrane fusion P
RCA
SceS000000146
GO:0016050 vesicle organization P
RCA
SceS000000146
GO:0035494 SNARE complex disassembly P
IDA
SceS000000146
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000146
ISS
SpoSPAC959.02
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000146
GO:0048284 organelle fusion P
RCA
SceS000000146
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC959.02

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GO info in one table:

s.khadayate@ucl.ac.uk