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Search term: YBL057C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PTH2
SGD link S000000153
Alternative ID YBL057C
Description One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth
Synonyms YBL057C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3282 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g03010 GI:15228442
Arabidopsis thaliana (Ath) At4g32900 GI:7486213
Arabidopsis thaliana (Ath) At5g16870 GI:11357729
Caenorhabditis elegans (Cel) CE17464
(WBGene00016062)
GI:17558188 O76387
Drosophila melanogaster (Dme) 7298895 GI:7298895
Homo sapiens (Hsa) Hs7706351
(PTRH2)
GI:7706351 Q9Y3E5
Saccharomyces cerevisiae (Sce) YBL057c
(S000000153)
GI:6319414 P34222
Schizosaccharomyces pombe (Spo) SPAC19A8.14 GI:19114690 O13830
Encephalitozoon cuniculi (Ecu) ECU04g0720 GI:19074149 Q8SVU8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g03010
GO:0005737 cytoplasm C
IC
SceS000000153
ISS
SpoSPAC19A8.14
GO:0005739 mitochondrion C
IDA
HsaPTRH2
SceS000000153
SpoSPAC19A8.14
ISS
SpoSPAC19A8.14
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000153
GO:0004045 aminoacyl-tRNA hydrolase activity F
IDA
SceS000000153
IGI
SceS000000153
ISS
SpoSPAC19A8.14
GO:0006412 translation P
ISS
SpoSPAC19A8.14
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000000153
IMP
SceS000000153
GO:0032543 mitochondrial translation P
NAS
SpoSPAC19A8.14
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016062

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5330

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PTRH2 GI:7706351 Q9Y3E5
Mus musculus (Mmu) Ptrh2
(MGI:2444848)
GI:33239415 Q8R2Y8
Rattus norvegicus (Rno) Ptrh2 GI:62078455
Gallus gallus (Gga) PTRH2 GI:94536825
Drosophila melanogaster (Dme) CG1307
(FBgn0026566)
GI:24644665
Anopheles gambiae (Aga) AgaP_AGAP003883 GI:158285075
Schizosaccharomyces pombe (Spo) SPAC19A8.14 GI:19114690 O13830
Saccharomyces cerevisiae (Sce) PTH2
(S000000153)
GI:6319414 P34222
Kluyveromyces lactis (Kla) KLLA0E20119g GI:50309691
Eremothecium gossypii (Ego) AGOS_ABR210W GI:45185442
Arabidopsis thaliana (Ath) AT5G16870 GI:18418110
Arabidopsis thaliana (Ath) AT3G03010 GI:79312699
Oryza sativa (Osa) Os04g0652900 GI:115461004


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g03010
GO:0005737 cytoplasm C
IC
SceS000000153
ISS
SpoSPAC19A8.14
GO:0005739 mitochondrion C
IDA
HsaPTRH2
MmuMGI:2444848
SceS000000153
SpoSPAC19A8.14
ISS
DmeFBgn0026566
SpoSPAC19A8.14
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000153
GO:0004045 aminoacyl-tRNA hydrolase activity F
IDA
SceS000000153
IGI
SceS000000153
ISS
DmeFBgn0026566
SpoSPAC19A8.14
GO:0006399 tRNA metabolic process P
ISS
DmeFBgn0026566
GO:0006412 translation P
ISS
SpoSPAC19A8.14
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000000153
IMP
SceS000000153
GO:0032543 mitochondrial translation P
NAS
SpoSPAC19A8.14

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1092

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6387 ENSANGP00000017193
Anopheles gambiae (Aga) aga7877 ENSANGP00000027700
Ashbya gossypii (Ago) ago804 ABR210W
Arabidopsis thaliana (Ath) ath12323 At3g03010.1
Arabidopsis thaliana (Ath) ath21398 At4g32900.1
Arabidopsis thaliana (Ath) ath21399 At4g32900.2
Arabidopsis thaliana (Ath) ath23919 At5g16870.1
Caenorhabditis elegans (Cel) cel2586 C24G6.8
(CE17464;
WBGene00016062)
Candida glabrata (Cgl) cgl182 CAGL0A04323g
Cryptococcus neoformans (Cne) cne248 162.m02725
Dictyostelium discoideum (Ddi) ddi6276 DDB0203421
Debaryomyces hansenii (Dha) dha339 DEHA0A07656g
Drosophila melanogaster (Dme) dme11255 CG1307-PB
(FBgn0026566)
Drosophila melanogaster (Dme) dme12345 CG17327-PA
(FBgn0038107)
Danio rerio (Dre) dre26196 ENSDARP00000003595
Encephalitozoon cuniculi (Ecu) ecu787 19074149
Takifugu rubripes (Fru) fru26287 SINFRUP00000157833
Gallus gallus (Gga) gga9016 ENSGALP00000008254
(PTRH2)
Homo sapiens (Hsa) hsa14085 ENSP00000337494
Kluyveromyces lactis (Kla) kla3856 KLLA0E20119g
Mus musculus (Mmu) mmu4491 ENSMUSP00000058098
Neurospora crassa (Ncr) ncr1456 NCU01501.2
Oryza sativa (Osa) osa49358 5840.m00141
Oryza sativa (Osa) osa63822 6631.m00169
Oryza sativa (Osa) osa80808 8204.m00146
Plasmodium falciparum (Pfa) pfa3439 PFD0355c
Rattus norvegicus (Rno) rno5805 ENSRNOP00000005661
(RGD:1306819)
Q5XI86
Saccharomyces cerevisiae (Sce) sce185 YBL057C
(S000000153)
Schizosaccharomyces pombe (Spo) spo897 SPAC19A8.14 O13830
Yarrowia lipolytica (Yli) yli4990 YALI0E27412g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g03010
GO:0005737 cytoplasm C
IC
SceS000000153
ISS
SpoSPAC19A8.14
GO:0005739 mitochondrion C
IDA
SceS000000153
SpoSPAC19A8.14
ISS
DmeFBgn0026566
SpoSPAC19A8.14
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000153
GO:0004045 aminoacyl-tRNA hydrolase activity F
IDA
SceS000000153
IGI
SceS000000153
ISS
DmeFBgn0026566
SpoSPAC19A8.14
GO:0006399 tRNA metabolic process P
ISS
DmeFBgn0026566
GO:0006412 translation P
ISS
SpoSPAC19A8.14
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000000153
IMP
SceS000000153
GO:0032543 mitochondrial translation P
NAS
SpoSPAC19A8.14
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016062

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC19A8.14
(O13830)
YBL057C
(S000000153)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IC
SceS000000153
ISS
SpoSPAC19A8.14
GO:0005739 mitochondrion C
IDA
SceS000000153
SpoSPAC19A8.14
ISS
SpoSPAC19A8.14
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000153
GO:0004045 aminoacyl-tRNA hydrolase activity F
IDA
SceS000000153
IGI
SceS000000153
ISS
SpoSPAC19A8.14
GO:0006412 translation P
ISS
SpoSPAC19A8.14
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process
P
IDA
SceS000000153
IMP
SceS000000153
GO:0032543 mitochondrial translation P
NAS
SpoSPAC19A8.14

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GO info in one table:

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