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Search term: YBL064C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRX1
SGD link S000000160
Alternative ID YBL064C
Description Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated
Synonyms YBL064C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0854 ACDHY--

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs4758638
(PRDX6)		 GI:4758638 P30041
Homo sapiens (Hsa) Hs20470293 GI:20470293
Drosophila melanogaster (Dme) 7295884 GI:7295884 Q9VQI7
Saccharomyces cerevisiae (Sce) YBL064c
(S000000160)		 GI:6319407 P34227
Arabidopsis thaliana (Ath) At1g48130 GI:15221082
Drosophila melanogaster (Dme) 7303748 GI:7303748 A1Z892
Drosophila melanogaster (Dme) 7303747 GI:7303747
Caenorhabditis elegans (Cel) CE27607_2 GI:17543126
Homo sapiens (Hsa) Hs4758638
(PRDX6)		 GI:4758638 P30041
Homo sapiens (Hsa) Hs20470293 GI:20470293
Drosophila melanogaster (Dme) 7295884 GI:7295884 Q9VQI7
Saccharomyces cerevisiae (Sce) YBL064c
(S000000160)		 GI:6319407 P34227
Arabidopsis thaliana (Ath) At1g48130 GI:15221082
Drosophila melanogaster (Dme) 7303748 GI:7303748 A1Z892
Drosophila melanogaster (Dme) 7303747 GI:7303747
Caenorhabditis elegans (Cel) CE27607_2 GI:17543126


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g48130
GO:0005634 nucleus C
IDA
HsaPRDX6
GO:0005737 cytoplasm C
IDA
HsaPRDX6
GO:0005739 mitochondrion C
IDA
SceS000000160
ISS
SceS000000160
GO:0005829 cytosol C
NAS
HsaPRDX6
GO:0004623 phospholipase A2 activity F
IDA
HsaPRDX6
GO:0008379 thioredoxin peroxidase activity F
IDA
SceS000000160
IMP
SceS000000160
ISS
AthAt1g48130
SceS000000160
GO:0016209 antioxidant activity F
ISS
AthAt1g48130
NAS
HsaPRDX6
GO:0006979 response to oxidative stress P
IDA
HsaPRDX6
GO:0009269 response to desiccation P
TAS
AthAt1g48130
GO:0009395 phospholipid catabolic process P
IDA
HsaPRDX6
GO:0009636 response to toxin P
RCA
SceS000000160
GO:0010231 maintenance of seed dormancy P
TAS
AthAt1g48130
GO:0034599 cellular response to oxidative
stress		 P
IGI
SceS000000160
GO:0045454 cell redox homeostasis P
IDA
SceS000000160
IMP
SceS000000160
GO:0046686 response to cadmium ion P
IMP
SceS000000160
GO:0055114 oxidation reduction P
RCA
SceS000000160

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3606

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PRDX6 GI:4758638 P30041
Pan troglodytes (Ptr) PRDX6 GI:114565483
Pan troglodytes (Ptr) PRDX6 GI:114621471
Canis familiaris (Cfa) PRDX6 GI:73961355
Mus musculus (Mmu) Prdx6
(MGI:894320)		 GI:6671549 O08709
Rattus norvegicus (Rno) Prdx6
(RGD:71005)		 GI:16758348
Gallus gallus (Gga) PRDX6 GI:86129578
Drosophila melanogaster (Dme) Prx6005
(FBgn0031479)		 GI:24581278
Anopheles gambiae (Aga) TPX5 GI:58376628
Caenorhabditis elegans (Cel) prdx-6
(CE31640;
WBGene00021401)		 GI:25153706
Saccharomyces cerevisiae (Sce) PRX1
(S000000160)		 GI:6319407 P34227
Kluyveromyces lactis (Kla) KLLA0E20383g GI:50309715
Eremothecium gossypii (Ego) AGOS_AGR368W GI:45201464
Magnaporthe grisea (Mgr) MGG_08256 GI:145613040
Neurospora crassa (Ncr) NCU06031.1 GI:32410811
Arabidopsis thaliana (Ath) ATPER1 GI:15221082
Oryza sativa (Osa) Os07g0638300 GI:115473617
Oryza sativa (Osa) Os07g0638400 GI:115473619
Plasmodium falciparum (Pfa) PF1cyspxn GI:124512718


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthATPER1
GO:0005634 nucleus C
IDA
HsaPRDX6
GO:0005737 cytoplasm C
IDA
HsaPRDX6
GO:0005739 mitochondrion C
IDA
MmuMGI:894320
SceS000000160
ISS
SceS000000160
GO:0005829 cytosol C
IDA
DmeFBgn0031479
MmuMGI:894320
NAS
HsaPRDX6
GO:0004601 peroxidase activity F
IMP
MmuMGI:894320
NAS
DmeFBgn0031479
GO:0004602 glutathione peroxidase activity F
ISO
MmuMGI:894320
ISS
DmeFBgn0031479
GO:0004623 phospholipase A2 activity F
IDA
HsaPRDX6
GO:0008379 thioredoxin peroxidase activity F
IDA
DmeFBgn0031479
SceS000000160
IMP
SceS000000160
ISS
AthATPER1
SceS000000160
GO:0016209 antioxidant activity F
ISS
AthATPER1
DmeFBgn0031479
NAS
DmeFBgn0031479
HsaPRDX6
GO:0000302 response to reactive oxygen species P
IMP
MmuMGI:894320
GO:0006979 response to oxidative stress P
IDA
HsaPRDX6
GO:0008152 metabolic process P
IMP
MmuMGI:894320
GO:0009269 response to desiccation P
TAS
AthATPER1
GO:0009395 phospholipid catabolic process P
IDA
HsaPRDX6
GO:0009636 response to toxin P
RCA
SceS000000160
GO:0010231 maintenance of seed dormancy P
TAS
AthATPER1
GO:0032060 bleb assembly P
IMP
MmuMGI:894320
GO:0034599 cellular response to oxidative
stress		 P
IGI
SceS000000160
GO:0042744 hydrogen peroxide catabolic process P
IDA
DmeFBgn0031479
ISO
MmuMGI:894320
GO:0045454 cell redox homeostasis P
IDA
SceS000000160
IMP
SceS000000160
ISS
DmeFBgn0031479
GO:0046686 response to cadmium ion P
IMP
SceS000000160
GO:0055114 oxidation reduction P
RCA
SceS000000160

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_472

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2470 ENSANGP00000015116
Anopheles gambiae (Aga) aga3526 ENSANGP00000015752
Anopheles gambiae (Aga) aga8979 ENSANGP00000020201
Ashbya gossypii (Ago) ago852 ACL197W
Ashbya gossypii (Ago) ago4679 AGR368W
Arabidopsis thaliana (Ath) ath4074 At1g48130.1
Caenorhabditis elegans (Cel) cel18304 Y38C1AA.11
(CE31640;
WBGene00021401)
Caenorhabditis elegans (Cel) cel18306 Y38C1AA.1a
(CE31641;
WBGene00021394)
Caenorhabditis elegans (Cel) cel18308 Y38C1AA.1c
(CE33860)
Candida glabrata (Cgl) cgl187 CAGL0A04433g
Cryptococcus neoformans (Cne) cne3439 176.m02498
Dictyostelium discoideum (Ddi) ddi5428 DDB0204808
Debaryomyces hansenii (Dha) dha2223 DEHA0C17908g
Debaryomyces hansenii (Dha) dha4852 DEHA0F10593g
Drosophila melanogaster (Dme) dme17396 CG11757-PA
(FBgn0030288)
Drosophila melanogaster (Dme) dme4300 CG11765-PA
(FBgn0033518)
Drosophila melanogaster (Dme) dme4303 CG12405-PA
(FBgn0033520)
Drosophila melanogaster (Dme) dme4304 CG12896-PA
(FBgn0033521)
Drosophila melanogaster (Dme) dme487 CG3083-PA
(FBgn0031479)
Danio rerio (Dre) dre12109 ENSDARP00000016325
Danio rerio (Dre) dre5370 ENSDARP00000039690
Takifugu rubripes (Fru) fru1568 SINFRUP00000129081
Takifugu rubripes (Fru) fru25832 SINFRUP00000129407
Takifugu rubripes (Fru) fru8013 SINFRUP00000147118
Takifugu rubripes (Fru) fru25831 SINFRUP00000176062
Gallus gallus (Gga) gga22208 ENSGALP00000004816
(PRDX6)
Gallus gallus (Gga) gga22209 ENSGALP00000004817
(PRDX6)		 Q5ZJF4
Gallus gallus (Gga) gga11135 ENSGALP00000024689
(RCJMB04_19b17)		 Q5ZJD8
Gallus gallus (Gga) gga11136 ENSGALP00000024690
Gallus gallus (Gga) gga11137 ENSGALP00000024697
(LOC421125)
Homo sapiens (Hsa) hsa2624 ENSP00000236251
Homo sapiens (Hsa) hsa30314 ENSP00000335416
(TMEM68)		 Q96MH6-2
Kluyveromyces lactis (Kla) kla114 KLLA0A02651g
Kluyveromyces lactis (Kla) kla3868 KLLA0E20383g
Mus musculus (Mmu) mmu1334 ENSMUSP00000028025
(MGI:894320)		 Q8BPD3
Mus musculus (Mmu) mmu17769 ENSMUSP00000029891
(MGI:1919348)		 Q9D850-1
Mus musculus (Mmu) mmu14855 ENSMUSP00000054562
(MGI:1336888)		 Q8BG37
Mus musculus (Mmu) mmu1333 ENSMUSP00000071636
(MGI:894320)		 Q6A0D0
Neurospora crassa (Ncr) ncr5861 NCU06031.2
Oryza sativa (Osa) osa71076 6994.m00186
Oryza sativa (Osa) osa71077 6994.m00187
Plasmodium falciparum (Pfa) pfa1905 PF08_0131
Rattus norvegicus (Rno) rno9365 ENSRNOP00000003961
(RGD:71005)
Rattus norvegicus (Rno) rno22710 ENSRNOP00000012215
(RGD:1309006)
Rattus norvegicus (Rno) rno9364 ENSRNOP00000030323
(RGD:71005)		 O35244
Saccharomyces cerevisiae (Sce) sce193 YBL064C
(S000000160)
Yarrowia lipolytica (Yli) yli657 YALI0A19426g
Yarrowia lipolytica (Yli) yli5688 YALI0F08195g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g48130
MmuMGI:1919348
GO:0005739 mitochondrion C
IDA
MmuMGI:894320
SceS000000160
ISS
SceS000000160
GO:0005829 cytosol C
IDA
DmeFBgn0033520
FBgn0033518
FBgn0031479
MmuMGI:894320
GO:0003674 molecular_function F
ND
MmuMGI:1919348
GO:0004601 peroxidase activity F
IMP
MmuMGI:894320
ISS
DmeFBgn0033518
PfaPF08_0131
NAS
DmeFBgn0033520
FBgn0033518
FBgn0031479
GO:0004602 glutathione peroxidase activity F
ISO
MmuMGI:894320
ISS
DmeFBgn0031479
FBgn0033520
FBgn0033518
GO:0008379 thioredoxin peroxidase activity F
IDA
DmeFBgn0033520
FBgn0033518
FBgn0031479
SceS000000160
IMP
SceS000000160
ISS
AthAt1g48130
SceS000000160
GO:0016209 antioxidant activity F
ISS
AthAt1g48130
DmeFBgn0033520
FBgn0033518
FBgn0031479
NAS
DmeFBgn0033518
FBgn0031479
FBgn0033520
GO:0000302 response to reactive oxygen species P
IMP
MmuMGI:894320
GO:0006979 response to oxidative stress P
ISS
PfaPF08_0131
GO:0007498 mesoderm development P
IEP
DmeFBgn0033521
GO:0008150 biological_process P
ND
MmuMGI:1919348
GO:0008152 metabolic process P
IMP
MmuMGI:894320
GO:0009269 response to desiccation P
TAS
AthAt1g48130
GO:0009636 response to toxin P
RCA
SceS000000160
GO:0010231 maintenance of seed dormancy P
TAS
AthAt1g48130
GO:0032060 bleb assembly P
IMP
MmuMGI:894320
GO:0034599 cellular response to oxidative
stress		 P
IGI
SceS000000160
GO:0042744 hydrogen peroxide catabolic process P
IDA
DmeFBgn0033518
FBgn0031479
FBgn0033520
ISO
MmuMGI:894320
GO:0045454 cell redox homeostasis P
IDA
SceS000000160
IMP
SceS000000160
ISS
DmeFBgn0031479
GO:0046686 response to cadmium ion P
IMP
SceS000000160
GO:0055114 oxidation reduction P
RCA
SceS000000160

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Search for gene by ID or name:

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GO info in one table:

s.khadayate@ucl.ac.uk