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Search term: YBL088C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TEL1
SGD link S000000184
Alternative ID YBL088C
Description Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene
Synonyms YBL088C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0892 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Protein kinase ATM/Tel1, involved in telomere length regulation and DNA repair

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g48190 GI:15228357
Caenorhabditis elegans (Cel) CE22176 GI:17510105
Drosophila melanogaster (Dme) 7299977 GI:7299977
Homo sapiens (Hsa) Hs20336199 GI:20336199 Q13315
Homo sapiens (Hsa) Hs20336201 GI:20336201
Homo sapiens (Hsa) Hs20336203 GI:20336203
Saccharomyces cerevisiae (Sce) YBL088c
(S000000184)		 GI:6319383 P38110
Schizosaccharomyces pombe (Spo) SPCC23B6.03c GI:19075626 O74630
Arabidopsis thaliana (Ath) At3g48190 GI:15228357
Caenorhabditis elegans (Cel) CE22176 GI:17510105
Drosophila melanogaster (Dme) 7299977 GI:7299977
Homo sapiens (Hsa) Hs20336199 GI:20336199 Q13315
Homo sapiens (Hsa) Hs20336201 GI:20336201
Homo sapiens (Hsa) Hs20336203 GI:20336203
Saccharomyces cerevisiae (Sce) YBL088c
(S000000184)		 GI:6319383 P38110
Schizosaccharomyces pombe (Spo) SPCC23B6.03c GI:19075626 O74630


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000184
GO:0005739 mitochondrion C
IDA
SceS000000184
GO:0005829 cytosol C
IDA
SpoSPCC23B6.03c
GO:0009507 chloroplast C
IDA
AthAt3g48190
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
TAS
AthAt3g48190
GO:0004672 protein kinase activity F
IDA
SceS000000184
TAS
SpoSPCC23B6.03c
GO:0005515 protein binding F
IPI
SpoSPCC23B6.03c
GO:0042162 telomeric DNA binding F
IDA
SceS000000184
GO:0000077 DNA damage checkpoint P
NAS
SpoSPCC23B6.03c
GO:0000723 telomere maintenance P
IMP
SceS000000184
SpoSPCC23B6.03c
GO:0006281 DNA repair P
IMP
AthAt3g48190
GO:0006302 double-strand break repair P
IGI
SceS000000184
IMP
SceS000000184
GO:0006974 response to DNA damage stimulus P
IMP
SceS000000184
GO:0006975 DNA damage induced protein phosphorylation P
IMP
SceS000000184
GO:0007126 meiosis P
IMP
AthAt3g48190
GO:0010212 response to ionizing radiation P
IMP
AthAt3g48190
GO:0010332 response to gamma radiation P
IMP
AthAt3g48190
GO:0016310 phosphorylation P
IMP
SceS000000184
GO:0016572 histone phosphorylation P
IGI
SceS000000184
SpoSPCC23B6.03c
IMP
SceS000000184
GO:0032204 regulation of telomere maintenance P
IGI
AthAt3g48190
GO:0032504 multicellular organism reproduction P
IGI
AthAt3g48190
GO:0033044 regulation of chromosome organization P
IGI
AthAt3g48190
GO:0043247 telomere maintenance in response to DNA
damage		 P
TAS
AthAt3g48190
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000184

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38348

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) TEL1
(S000000184)		 GI:6319383 P38110
Kluyveromyces lactis (Kla) KLLA0E06963g GI:50308521
Eremothecium gossypii (Ego) AGOS_AGL287W GI:45200810


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000184
GO:0005739 mitochondrion C
IDA
SceS000000184
GO:0004672 protein kinase activity F
IDA
SceS000000184
GO:0042162 telomeric DNA binding F
IDA
SceS000000184
GO:0000723 telomere maintenance P
IMP
SceS000000184
GO:0006302 double-strand break repair P
IGI
SceS000000184
IMP
SceS000000184
GO:0006974 response to DNA damage stimulus P
IMP
SceS000000184
GO:0006975 DNA damage induced protein phosphorylation P
IMP
SceS000000184
GO:0016310 phosphorylation P
IMP
SceS000000184
GO:0016572 histone phosphorylation P
IGI
SceS000000184
IMP
SceS000000184
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000184

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3841

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11825 ENSANGP00000025430
Ashbya gossypii (Ago) ago4025 AGL287W
Arabidopsis thaliana (Ath) ath16120 At3g48190.1
Caenorhabditis elegans (Cel) cel19274 Y48G1BL.2
(CE30018;
WBGene00000227)
Candida glabrata (Cgl) cgl2262 CAGL0H04609g
Cryptococcus neoformans (Cne) cne1404 180.m00352
Debaryomyces hansenii (Dha) dha1672 DEHA0C05456g
Drosophila melanogaster (Dme) dme12697 CG6535-PA
(FBgn0045035)
Danio rerio (Dre) dre6808 ENSDARP00000015167
(atm)		 Q59IS5
Takifugu rubripes (Fru) fru17062 SINFRUP00000141376
Gallus gallus (Gga) gga3223 ENSGALP00000027660
(ATM)
Homo sapiens (Hsa) hsa6509 ENSP00000278616
(ATM)		 Q13315-1
Kluyveromyces lactis (Kla) kla3262 KLLA0E06963g
Mus musculus (Mmu) mmu27635 ENSMUSP00000045039
(MGI:107202)		 Q62388
Neurospora crassa (Ncr) ncr262 NCU00274.2
Oryza sativa (Osa) osa19374 3358.m00190
Oryza sativa (Osa) osa38343 5057.m00182
Rattus norvegicus (Rno) rno28608 ENSRNOP00000045529
(RGD:1593265)
Saccharomyces cerevisiae (Sce) sce220 YBL088C
(S000000184)
Schizosaccharomyces pombe (Spo) spo4496 SPCC23B6.03c O74630
Yarrowia lipolytica (Yli) yli2864 YALI0D03888g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
CelWBGene00000227
GO:0005634 nucleus C
IC
SceS000000184
ISO
MmuMGI:107202
TAS
MmuMGI:107202
GO:0005654 nucleoplasm C
EXP
MmuMGI:107202
GO:0005737 cytoplasm C
ISO
MmuMGI:107202
GO:0005739 mitochondrion C
IDA
SceS000000184
GO:0005819 spindle C
IDA
MmuMGI:107202
GO:0005829 cytosol C
IDA
SpoSPCC23B6.03c
GO:0009507 chloroplast C
IDA
AthAt3g48190
GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase
activity		 F
TAS
AthAt3g48190
GO:0004672 protein kinase activity F
IDA
MmuMGI:107202
SceS000000184
ISS
DmeFBgn0045035
NAS
DmeFBgn0045035
TAS
MmuMGI:107202
SpoSPCC23B6.03c
GO:0004674 protein serine/threonine kinase
activity		 F
ISO
MmuMGI:107202
GO:0005515 protein binding F
IPI
MmuMGI:107202
SpoSPCC23B6.03c
GO:0016301 kinase activity F
EXP
MmuMGI:107202
GO:0035174 histone serine kinase activity F
ISO
MmuMGI:107202
GO:0042162 telomeric DNA binding F
IDA
SceS000000184
GO:0000075 cell cycle checkpoint P
ISS
DmeFBgn0045035
GO:0000077 DNA damage checkpoint P
IMP
MmuMGI:107202
NAS
SpoSPCC23B6.03c
GO:0000723 telomere maintenance P
IMP
DmeFBgn0045035
SceS000000184
SpoSPCC23B6.03c
GO:0001666 response to hypoxia P
ISO
MmuMGI:107202
GO:0001756 somitogenesis P
IGI
MmuMGI:107202
GO:0002331 pre-B cell allelic exclusion P
IMP
MmuMGI:107202
GO:0006281 DNA repair P
IDA
MmuMGI:107202
IMP
AthAt3g48190
MmuMGI:107202
GO:0006302 double-strand break repair P
IGI
SceS000000184
IMP
SceS000000184
GO:0006348 chromatin silencing at telomere P
IMP
DmeFBgn0045035
GO:0006468 protein amino acid phosphorylation P
IDA
MmuMGI:107202
GO:0006974 response to DNA damage stimulus P
IMP
SceS000000184
ISO
MmuMGI:107202
TAS
MmuMGI:107202
GO:0006975 DNA damage induced protein phosphorylation P
IMP
SceS000000184
GO:0007093 mitotic cell cycle checkpoint P
IGI
DmeFBgn0045035
GO:0007126 meiosis P
IMP
AthAt3g48190
GO:0007292 female gamete generation P
IMP
MmuMGI:107202
GO:0007420 brain development P
IGI
MmuMGI:107202
GO:0007507 heart development P
IGI
MmuMGI:107202
GO:0008630 DNA damage response, signal transduction resulting
in induction of apoptosis		 P
IGI
MmuMGI:107202
IMP
MmuMGI:107202
GO:0010212 response to ionizing radiation P
IGI
MmuMGI:107202
IMP
AthAt3g48190
GO:0010332 response to gamma radiation P
IMP
AthAt3g48190
GO:0016233 telomere capping P
IMP
DmeFBgn0045035
GO:0016310 phosphorylation P
EXP
MmuMGI:107202
IMP
SceS000000184
NAS
DmeFBgn0045035
TAS
MmuMGI:107202
GO:0016572 histone phosphorylation P
IGI
SceS000000184
SpoSPCC23B6.03c
IMP
SceS000000184
ISO
MmuMGI:107202
GO:0031572 G2/M transition DNA damage checkpoint P
IMP
DmeFBgn0045035
GO:0032204 regulation of telomere maintenance P
IGI
AthAt3g48190
GO:0032504 multicellular organism reproduction P
IGI
AthAt3g48190
GO:0033044 regulation of chromosome organization P
IGI
AthAt3g48190
GO:0042159 lipoprotein catabolic process P
IGI
MmuMGI:107202
GO:0043066 negative regulation of apoptosis P
IMP
MmuMGI:107202
GO:0043247 telomere maintenance in response to DNA
damage		 P
TAS
AthAt3g48190
GO:0043525 positive regulation of neuron apoptosis P
IGI
MmuMGI:107202
GO:0045494 photoreceptor cell maintenance P
IMP
DmeFBgn0045035
GO:0046777 protein amino acid autophosphorylation P
ISO
MmuMGI:107202
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000184
GO:0051276 chromosome organization P
IMP
DmeFBgn0045035
GO:0051402 neuron apoptosis P
IGI
MmuMGI:107202
GO:0051726 regulation of cell cycle P
ISO
MmuMGI:107202

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC23B6.03c
(O74630)		 YBL088C
(S000000184)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000184
GO:0005739 mitochondrion C
IDA
SceS000000184
GO:0005829 cytosol C
IDA
SpoSPCC23B6.03c
GO:0004672 protein kinase activity F
IDA
SceS000000184
TAS
SpoSPCC23B6.03c
GO:0005515 protein binding F
IPI
SpoSPCC23B6.03c
GO:0042162 telomeric DNA binding F
IDA
SceS000000184
GO:0000077 DNA damage checkpoint P
NAS
SpoSPCC23B6.03c
GO:0000723 telomere maintenance P
IMP
SceS000000184
SpoSPCC23B6.03c
GO:0006302 double-strand break repair P
IGI
SceS000000184
IMP
SceS000000184
GO:0006974 response to DNA damage stimulus P
IMP
SceS000000184
GO:0006975 DNA damage induced protein phosphorylation P
IMP
SceS000000184
GO:0016310 phosphorylation P
IMP
SceS000000184
GO:0016572 histone phosphorylation P
IGI
SceS000000184
SpoSPCC23B6.03c
IMP
SceS000000184
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000000184

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Search for gene by ID or name:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk