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Search term: YBL091C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MAP2
SGD link S000000187
Alternative ID YBL091C
Description Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p
Synonyms YBL091C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2775 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Metallopeptidase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g44180 GI:7435570
Arabidopsis thaliana (Ath) At3g59990 GI:11264654
Caenorhabditis elegans (Cel) CE03743
(WBGene00012075)
GI:17570097 P50581
Caenorhabditis elegans (Cel) CE10898 GI:17507525
Caenorhabditis elegans (Cel) CE24146
(WBGene00003130)
GI:17544396 Q9U2V9
Drosophila melanogaster (Dme) 7297553
(FBgn0025117)
GI:17137568
Homo sapiens (Hsa) Hs5803092
(METAP2)
GI:5803092 P50579
Homo sapiens (Hsa) Hs17441560 GI:17441560
Saccharomyces cerevisiae (Sce) YBL091c
(S000000187)
GI:6319380 P38174
Schizosaccharomyces pombe (Spo) SPBC14C8.03 GI:19112698 O60085
Encephalitozoon cuniculi (Ecu) ECU10g0750 GI:19074684


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
AthAt3g59990
At2g44180
HsaMETAP2
ISS
SpoSPBC14C8.03
TAS
SceS000000187
GO:0005829 cytosol C
IDA
SpoSPBC14C8.03
GO:0004177 aminopeptidase activity F
IDA
HsaMETAP2
ISS
DmeFBgn0025117
SpoSPBC14C8.03
NAS
DmeFBgn0025117
GO:0008235 metalloexopeptidase activity F
IDA
HsaMETAP2
GO:0070006 metalloaminopeptidase activity F
IGI
SceS000000187
ISA
SceS000000187
GO:0000003 reproduction P
IMP
CelWBGene00003130
GO:0006508 proteolysis P
IDA
SceS000000187
ISS
SpoSPBC14C8.03
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00003130
GO:0007276 gamete generation P
IMP
CelWBGene00003130
GO:0008406 gonad development P
IMP
CelWBGene00003130
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003130
GO:0016485 protein processing P
IDA
HsaMETAP2
TAS
AthAt3g59990
GO:0018206 peptidyl-methionine modification P
IDA
HsaMETAP2
GO:0031365 N-terminal protein amino acid modification P
IDA
HsaMETAP2
TAS
AthAt2g44180
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003130
GO:0070084 protein initiator methionine removal P
ISS
SpoSPBC14C8.03

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4981

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) METAP2 GI:5803092 P50579
Pan troglodytes (Ptr) METAP2 GI:114646288
Canis familiaris (Cfa) METAP2 GI:73977621
Mus musculus (Mmu) Metap2
(MGI:1929701)
GI:9789873 O08663
Rattus norvegicus (Rno) Metap2
(RGD:70995)
GI:11993954
Gallus gallus (Gga) METAP2 GI:57525368
Drosophila melanogaster (Dme) und
(FBgn0025117)
GI:17137568
Anopheles gambiae (Aga) AgaP_AGAP008345 GI:158296764
Schizosaccharomyces pombe (Spo) fma2
(SPBC14C8.03)
GI:19112698 O60085
Saccharomyces cerevisiae (Sce) MAP2
(S000000187)
GI:6319380 P38174
Kluyveromyces lactis (Kla) KLLA0E06875g GI:50308513
Eremothecium gossypii (Ego) AGOS_AGL283W GI:54299398
Magnaporthe grisea (Mgr) MGG_00966 GI:145610691
Neurospora crassa (Ncr) NCU04306.1 GI:32406066
Arabidopsis thaliana (Ath) MAP2A GI:18406472
Arabidopsis thaliana (Ath) MAP2B GI:79315754
Oryza sativa (Osa) Os12g0628500 GI:115489686
Oryza sativa (Osa) Os08g0542000 GI:115477587
Plasmodium falciparum (Pfa) PF14_0327 GI:124809144


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0327
GO:0005737 cytoplasm C
IDA
AthMAP2A
MAP2B
HsaMETAP2
ISS
SpoSPBC14C8.03
TAS
SceS000000187
GO:0005829 cytosol C
IDA
SpoSPBC14C8.03
GO:0004177 aminopeptidase activity F
IDA
HsaMETAP2
ISS
DmeFBgn0025117
SpoSPBC14C8.03
NAS
DmeFBgn0025117
GO:0005515 protein binding F
IPI
MmuMGI:1929701
GO:0008235 metalloexopeptidase activity F
IDA
HsaMETAP2
GO:0070006 metalloaminopeptidase activity F
IGI
SceS000000187
ISA
SceS000000187
GO:0006412 translation P
ISS
PfaPF14_0327
GO:0006417 regulation of translation P
ISS
PfaPF14_0327
GO:0006464 protein modification process P
ISS
PfaPF14_0327
GO:0006508 proteolysis P
IDA
SceS000000187
ISS
SpoSPBC14C8.03
GO:0016485 protein processing P
IDA
HsaMETAP2
TAS
AthMAP2B
GO:0018206 peptidyl-methionine modification P
IDA
HsaMETAP2
GO:0031365 N-terminal protein amino acid modification P
IDA
HsaMETAP2
TAS
AthMAP2A
GO:0070084 protein initiator methionine removal P
ISS
SpoSPBC14C8.03

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_966

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga10337 ENSANGP00000019665
Ashbya gossypii (Ago) ago4029 AGL283W
Arabidopsis thaliana (Ath) ath11628 At2g44180.1
Arabidopsis thaliana (Ath) ath17424 At3g59990.1
Arabidopsis thaliana (Ath) ath17425 At3g59990.2
Caenorhabditis elegans (Cel) cel17709 Y116A8A.9
(CE24146;
WBGene00003130)
Candida glabrata (Cgl) cgl1783 CAGL0G03641g
Cryptococcus neoformans (Cne) cne4374 177.m03126
Dictyostelium discoideum (Ddi) ddi3394 DDB0190923
Debaryomyces hansenii (Dha) dha1625 DEHA0C04444g
Drosophila melanogaster (Dme) dme1643 CG4008-PA
(FBgn0025117)
Danio rerio (Dre) dre10976 ENSDARP00000029383
Encephalitozoon cuniculi (Ecu) ecu600 19074684
Takifugu rubripes (Fru) fru5624 SINFRUP00000129935
Takifugu rubripes (Fru) fru23294 SINFRUP00000148667
Takifugu rubripes (Fru) fru23296 SINFRUP00000167892
Takifugu rubripes (Fru) fru5625 SINFRUP00000170146
Takifugu rubripes (Fru) fru23295 SINFRUP00000175225
Gallus gallus (Gga) gga628 ENSGALP00000018536
Gallus gallus (Gga) gga626 ENSGALP00000018537
(METAP2)
Q5ZIL5
Gallus gallus (Gga) gga627 ENSGALP00000018538
Homo sapiens (Hsa) hsa8006 ENSP00000261220
(METAP2)
B4DUX5
Homo sapiens (Hsa) hsa8005 ENSP00000325312
(METAP2)
P50579
Kluyveromyces lactis (Kla) kla3258 KLLA0E06875g
Mus musculus (Mmu) mmu2749 ENSMUSP00000048285
(MGI:1929701)
Q3UI33
Neurospora crassa (Ncr) ncr4182 NCU04306.2
Oryza sativa (Osa) osa65880 6881.m00188
Oryza sativa (Osa) osa65898 6881.m00236
Oryza sativa (Osa) osa77880 7330.m00102
Plasmodium falciparum (Pfa) pfa1778 PF14_0327
Rattus norvegicus (Rno) rno14187 ENSRNOP00000021149
Rattus norvegicus (Rno) rno26652 ENSRNOP00000030415
(RGD:70995)
Q6IRK1
Saccharomyces cerevisiae (Sce) sce223 YBL091C
(S000000187)
Schizosaccharomyces pombe (Spo) spo747 SPBC14C8.03 O60085
Yarrowia lipolytica (Yli) yli2917 YALI0D05159g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0327
GO:0005737 cytoplasm C
IDA
AthAt3g59990
At2g44180
ISS
SpoSPBC14C8.03
TAS
SceS000000187
GO:0005829 cytosol C
IDA
SpoSPBC14C8.03
GO:0004177 aminopeptidase activity F
ISS
DmeFBgn0025117
SpoSPBC14C8.03
NAS
DmeFBgn0025117
GO:0005515 protein binding F
IPI
MmuMGI:1929701
GO:0070006 metalloaminopeptidase activity F
IGI
SceS000000187
ISA
SceS000000187
GO:0000003 reproduction P
IMP
CelWBGene00003130
GO:0006412 translation P
ISS
PfaPF14_0327
GO:0006417 regulation of translation P
ISS
PfaPF14_0327
GO:0006464 protein modification process P
ISS
PfaPF14_0327
GO:0006508 proteolysis P
IDA
SceS000000187
ISS
SpoSPBC14C8.03
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00003130
GO:0007276 gamete generation P
IMP
CelWBGene00003130
GO:0008406 gonad development P
IMP
CelWBGene00003130
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003130
GO:0016485 protein processing P
TAS
AthAt3g59990
GO:0031365 N-terminal protein amino acid modification P
TAS
AthAt2g44180
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003130
GO:0070084 protein initiator methionine removal P
ISS
SpoSPBC14C8.03

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC14C8.03
(O60085)
YBL091C
(S000000187)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
ISS
SpoSPBC14C8.03
TAS
SceS000000187
GO:0005829 cytosol C
IDA
SpoSPBC14C8.03
GO:0004177 aminopeptidase activity F
ISS
SpoSPBC14C8.03
GO:0070006 metalloaminopeptidase activity F
IGI
SceS000000187
ISA
SceS000000187
GO:0006508 proteolysis P
IDA
SceS000000187
ISS
SpoSPBC14C8.03
GO:0070084 protein initiator methionine removal P
ISS
SpoSPBC14C8.03

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Search for gene by ID or name:

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk