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Search term: YBR037C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SCO1
SGD link S000000241
Alternative ID YBR037C
Description Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins
Synonyms YBR037C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2792 ACDHYP-

KOGs classification KOGs description
METABOLISM Putative cytochrome C oxidase assembly protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g08950 GI:6403490
Arabidopsis thaliana (Ath) At4g39740 GI:7487210
Caenorhabditis elegans (Cel) CE06743
(WBGene00015297)		 GI:17531419 Q17557
Drosophila melanogaster (Dme) 7296911
(FBgn0031656)		 GI:19920710
Homo sapiens (Hsa) Hs4759068
(SCO1)		 GI:4759068 O75880
Homo sapiens (Hsa) Hs4826992 GI:4826992
Saccharomyces cerevisiae (Sce) YBR024w
(S000000228)		 GI:6319498 P38072
Saccharomyces cerevisiae (Sce) YBR037c
(S000000241)		 GI:6319511 P23833
Schizosaccharomyces pombe (Spo) SPBC119.06 GI:19112079 O42899


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000241
S000000228
ISS
DmeFBgn0031656
GO:0005740 mitochondrial envelope C
IDA
SceS000000228
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000241
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0003674 molecular_function F
ND
AthAt4g39740
GO:0005507 copper ion binding F
IDA
SceS000000241
ISS
SpoSPBC119.06
GO:0008379 thioredoxin peroxidase activity F
ISS
SceS000000241
S000000228
GO:0016531 copper chaperone activity F
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0043167 ion binding F
RCA
SceS000000228
GO:0043169 cation binding F
RCA
SceS000000228
GO:0046872 metal ion binding F
RCA
SceS000000228
GO:0046914 transition metal ion binding F
RCA
SceS000000228
GO:0000003 reproduction P
IMP
CelWBGene00015297
GO:0002119 nematode larval development P
IMP
CelWBGene00015297
GO:0006091 generation of precursor metabolites and
energy		 P
TAS
HsaSCO1
GO:0006461 protein complex assembly P
IMP
SceS000000241
GO:0006825 copper ion transport P
IGI
SceS000000241
ISS
SceS000000228
S000000241
SpoSPBC119.06
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00015297
GO:0008535 respiratory chain complex IV assembly P
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015297
GO:0040007 growth P
IMP
CelWBGene00015297
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00015297
GO:0051775 response to redox state P
ISS
SceS000000241

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3374

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SCO1 GI:4759068 O75880
Pan troglodytes (Ptr) SCO1 GI:114669051
Canis familiaris (Cfa) SCO1 GI:73955918
Mus musculus (Mmu) Sco1
(MGI:106362)		 GI:90991710 Q3TJT6
Rattus norvegicus (Rno) Sco1 GI:109488326
Gallus gallus (Gga) SCO1 GI:50795003
Drosophila melanogaster (Dme) CG8885
(FBgn0031656)		 GI:19920710
Anopheles gambiae (Aga) AgaP_AGAP008774 GI:118785805
Caenorhabditis elegans (Cel) C01F1.2
(CE06743;
WBGene00015297)		 GI:17531419 Q17557
Schizosaccharomyces pombe (Spo) sco1
(SPBC119.06)		 GI:19112079 O42899
Saccharomyces cerevisiae (Sce) SCO1
(S000000241)		 GI:6319511 P23833
Kluyveromyces lactis (Kla) KLLA0D03630g GI:50306505
Eremothecium gossypii (Ego) AGOS_AEL191C GI:45190416
Magnaporthe grisea (Mgr) MGG_03006 GI:39971079
Neurospora crassa (Ncr) NCU03177.1 GI:32420339
Arabidopsis thaliana (Ath) AT3G08950 GI:18398306
Oryza sativa (Osa) Os02g0159700 GI:115444369
Plasmodium falciparum (Pfa) PF07_0034 GI:124511740


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:106362
SceS000000241
ISS
DmeFBgn0031656
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000241
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0003674 molecular_function F
ND
MmuMGI:106362
GO:0005507 copper ion binding F
IDA
SceS000000241
ISS
SpoSPBC119.06
GO:0008379 thioredoxin peroxidase activity F
ISS
SceS000000241
GO:0016531 copper chaperone activity F
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0000003 reproduction P
IMP
CelWBGene00015297
GO:0002119 nematode larval development P
IMP
CelWBGene00015297
GO:0006091 generation of precursor metabolites and
energy		 P
TAS
HsaSCO1
GO:0006461 protein complex assembly P
IMP
SceS000000241
GO:0006825 copper ion transport P
IGI
SceS000000241
ISS
SceS000000241
SpoSPBC119.06
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00015297
GO:0008150 biological_process P
ND
MmuMGI:106362
GO:0008535 respiratory chain complex IV assembly P
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015297
GO:0040007 growth P
IMP
CelWBGene00015297
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00015297
GO:0051775 response to redox state P
ISS
SceS000000241

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1572

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10824 ENSANGP00000012964
Ashbya gossypii (Ago) ago2315 AEL191C
Arabidopsis thaliana (Ath) ath12966 At3g08950.1
Caenorhabditis elegans (Cel) cel703 C01F1.2
(CE06743;
WBGene00015297)
Candida glabrata (Cgl) cgl394 CAGL0B04367g
Candida glabrata (Cgl) cgl2729 CAGL0I04796g
Dictyostelium discoideum (Ddi) ddi4807 DDB0205634
Debaryomyces hansenii (Dha) dha126 DEHA0A02849g
Drosophila melanogaster (Dme) dme794 CG8885-PA
(FBgn0031656)
Danio rerio (Dre) dre6359 ENSDARP00000040469
Danio rerio (Dre) dre6360 ENSDARP00000044604
Takifugu rubripes (Fru) fru21692 SINFRUP00000151240
Gallus gallus (Gga) gga26437 ENSGALP00000021792
(SCO1)
Homo sapiens (Hsa) hsa21937 ENSP00000252785
(SCO2)		 O43819
Homo sapiens (Hsa) hsa13079 ENSP00000255390
(SCO1)		 O75880
Kluyveromyces lactis (Kla) kla2225 KLLA0D03630g
Neurospora crassa (Ncr) ncr3079 NCU03177.2
Oryza sativa (Osa) osa28247 4241.m00232
Plasmodium falciparum (Pfa) pfa2364 PF07_0034
Rattus norvegicus (Rno) rno27597 ENSRNOP00000013325
Rattus norvegicus (Rno) rno5267 ENSRNOP00000031081
(RGD:1559538)
Rattus norvegicus (Rno) rno5268 ENSRNOP00000039202
(RGD:1559538)		 B0BNM7
Saccharomyces cerevisiae (Sce) sce277 YBR024W
(S000000228)
Saccharomyces cerevisiae (Sce) sce290 YBR037C
(S000000241)
Schizosaccharomyces pombe (Spo) spo2623 SPBC119.06 O42899
Yarrowia lipolytica (Yli) yli4813 YALI0E23045g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000241
S000000228
ISS
DmeFBgn0031656
GO:0005740 mitochondrial envelope C
IDA
SceS000000228
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000241
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0005507 copper ion binding F
IDA
SceS000000241
ISS
SpoSPBC119.06
GO:0008379 thioredoxin peroxidase activity F
ISS
SceS000000241
S000000228
GO:0016531 copper chaperone activity F
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0043167 ion binding F
RCA
SceS000000228
GO:0043169 cation binding F
RCA
SceS000000228
GO:0046872 metal ion binding F
RCA
SceS000000228
GO:0046914 transition metal ion binding F
RCA
SceS000000228
GO:0000003 reproduction P
IMP
CelWBGene00015297
GO:0002119 nematode larval development P
IMP
CelWBGene00015297
GO:0006461 protein complex assembly P
IMP
SceS000000241
GO:0006825 copper ion transport P
IGI
SceS000000241
ISS
SceS000000228
S000000241
SpoSPBC119.06
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00015297
GO:0008535 respiratory chain complex IV assembly P
ISS
DmeFBgn0031656
SpoSPBC119.06
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015297
GO:0040007 growth P
IMP
CelWBGene00015297
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00015297
GO:0051775 response to redox state P
ISS
SceS000000241

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC119.06
(O42899)		 YBR037C
(S000000241)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000241
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000241
ISS
SpoSPBC119.06
GO:0005507 copper ion binding F
IDA
SceS000000241
ISS
SpoSPBC119.06
GO:0008379 thioredoxin peroxidase activity F
ISS
SceS000000241
GO:0016531 copper chaperone activity F
ISS
SpoSPBC119.06
GO:0006461 protein complex assembly P
IMP
SceS000000241
GO:0006825 copper ion transport P
IGI
SceS000000241
ISS
SceS000000241
SpoSPBC119.06
GO:0008535 respiratory chain complex IV assembly P
ISS
SpoSPBC119.06
GO:0051775 response to redox state P
ISS
SceS000000241

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk