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Search term: YBR060C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ORC2
SGD link S000000264
Alternative ID YBR060C
Description Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p
Synonyms YBR060C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2928 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Origin recognition complex, subunit 2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g37560 GI:15224316
Caenorhabditis elegans (Cel) CE11492
(WBGene00003882)
GI:17534571 Q21037
Drosophila melanogaster (Dme) 7299828 GI:13124798
Homo sapiens (Hsa) Hs5453830
(ORC2L)
GI:5453830 Q13416
Saccharomyces cerevisiae (Sce) YBR060c
(S000000264)
GI:6319534 P32833
Schizosaccharomyces pombe (Spo) SPBC685.09 GI:19112935 Q09142
Encephalitozoon cuniculi (Ecu) ECU10g1130 GI:19074722 Q8SR28


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
CelWBGene00003882
GO:0000808 origin recognition complex C
IDA
HsaORC2L
ISS
AthAt2g37560
GO:0005654 nucleoplasm C
EXP
HsaORC2L
GO:0005656 pre-replicative complex C
IC
SpoSPBC685.09
IDA
SceS000000264
GO:0005664 nuclear origin of replication recognition
complex
C
IDA
SceS000000264
SpoSPBC685.09
IMP
SceS000000264
GO:0005816 spindle pole body C
IDA
SpoSPBC685.09
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC685.09
IDA
SceS000000264
GO:0032153 cell division site C
IDA
SpoSPBC685.09
GO:0043596 nuclear replication fork C
IC
SpoSPBC685.09
GO:0003682 chromatin binding F
IDA
SceS000000264
GO:0003688 DNA replication origin binding F
IDA
SceS000000264
SpoSPBC685.09
ISS
AthAt2g37560
GO:0005515 protein binding F
IPI
AthAt2g37560
HsaORC2L
GO:0000003 reproduction P
IMP
CelWBGene00003882
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
TAS
HsaORC2L
GO:0006260 DNA replication P
EXP
HsaORC2L
ISS
AthAt2g37560
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000264
GO:0006270 DNA-dependent DNA replication initiation P
IC
SpoSPBC685.09
IGI
SceS000000264
IMP
SceS000000264
TAS
HsaORC2L
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000264
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003882
GO:0010171 body morphogenesis P
IMP
CelWBGene00003882
GO:0016458 gene silencing P
RCA
SceS000000264
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IDA
SceS000000264
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003882
GO:0040011 locomotion P
IMP
CelWBGene00003882
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00003882
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00003882
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00003882
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003882
GO:0051568 histone H3-K4 methylation P
IMP
SceS000000264

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117730

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ORC2
(S000000264)
GI:6319534 P32833
Kluyveromyces lactis (Kla) KLLA0F18590g GI:50311769
Eremothecium gossypii (Ego) AGOS_AGR028C GI:45201123


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005656 pre-replicative complex C
IDA
SceS000000264
GO:0005664 nuclear origin of replication recognition
complex
C
IDA
SceS000000264
IMP
SceS000000264
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000000264
GO:0003682 chromatin binding F
IDA
SceS000000264
GO:0003688 DNA replication origin binding F
IDA
SceS000000264
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000264
GO:0006270 DNA-dependent DNA replication initiation P
IGI
SceS000000264
IMP
SceS000000264
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000264
GO:0016458 gene silencing P
RCA
SceS000000264
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IDA
SceS000000264
GO:0051568 histone H3-K4 methylation P
IMP
SceS000000264

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2692

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga15092 ENSANGP00000007433
Ashbya gossypii (Ago) ago4338 AGR028C
Arabidopsis thaliana (Ath) ath10843 At2g37560.1
Arabidopsis thaliana (Ath) ath10844 At2g37560.2
Caenorhabditis elegans (Cel) cel11091 F59E10.1
(CE11492;
WBGene00003882)
Candida glabrata (Cgl) cgl2509 CAGL0H10230g
Cryptococcus neoformans (Cne) cne3539 176.m02270
Dictyostelium discoideum (Ddi) ddi11563 DDB0231726
Debaryomyces hansenii (Dha) dha4705 DEHA0F07238g
Drosophila melanogaster (Dme) dme12510 CG3041-PA
(FBgn0015270)
Takifugu rubripes (Fru) fru8744 SINFRUP00000137842
Gallus gallus (Gga) gga21334 ENSGALP00000013386
(ORC2L)
Q5ZJL2
Homo sapiens (Hsa) hsa19082 ENSP00000234296
(ORC2L)
Q13416
Kluyveromyces lactis (Kla) kla4913 KLLA0F18590g
Mus musculus (Mmu) mmu381 ENSMUSP00000027198
(MGI:1328306)
Q60862
Neurospora crassa (Ncr) ncr1329 NCU01370.2
Oryza sativa (Osa) osa75457 7232.m00151
Plasmodium falciparum (Pfa) pfa2249 MAL7P1.21
Rattus norvegicus (Rno) rno30081 ENSRNOP00000016845
(RGD:1311844)
Rattus norvegicus (Rno) rno30080 ENSRNOP00000042867
(RGD:1311844)
Q75PQ8
Saccharomyces cerevisiae (Sce) sce315 YBR060C
(S000000264)
Schizosaccharomyces pombe (Spo) spo1052 SPBC685.09 Q09142
Yarrowia lipolytica (Yli) yli3641 YALI0D22330g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
CelWBGene00003882
GO:0000785 chromatin C
IDA
MmuMGI:1328306
GO:0000792 heterochromatin C
IDA
MmuMGI:1328306
GO:0000808 origin recognition complex C
ISS
AthAt2g37560
GO:0000939 inner kinetochore of condensed
chromosome
C
IDA
MmuMGI:1328306
GO:0005656 pre-replicative complex C
IC
SpoSPBC685.09
IDA
SceS000000264
GO:0005664 nuclear origin of replication recognition
complex
C
IDA
DmeFBgn0015270
MmuMGI:1328306
SceS000000264
SpoSPBC685.09
IMP
SceS000000264
ISS
DmeFBgn0015270
PfaMAL7P1.21
NAS
DmeFBgn0015270
GO:0005816 spindle pole body C
IDA
SpoSPBC685.09
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC685.09
IDA
SceS000000264
GO:0032153 cell division site C
IDA
SpoSPBC685.09
GO:0043596 nuclear replication fork C
IC
SpoSPBC685.09
GO:0003677 DNA binding F
NAS
DmeFBgn0015270
GO:0003682 chromatin binding F
IDA
SceS000000264
GO:0003688 DNA replication origin binding F
IDA
MmuMGI:1328306
SceS000000264
SpoSPBC685.09
ISS
AthAt2g37560
PfaMAL7P1.21
GO:0005515 protein binding F
IPI
AthAt2g37560
GO:0000003 reproduction P
IMP
CelWBGene00003882
GO:0006260 DNA replication P
IMP
DmeFBgn0015270
ISS
AthAt2g37560
DmeFBgn0015270
TAS
DmeFBgn0015270
GO:0006261 DNA-dependent DNA replication P
ISS
DmeFBgn0015270
NAS
DmeFBgn0015270
GO:0006267 pre-replicative complex assembly P
IDA
SceS000000264
GO:0006270 DNA-dependent DNA replication initiation P
IC
SpoSPBC685.09
IDA
DmeFBgn0015270
IGI
SceS000000264
IMP
SceS000000264
ISS
PfaMAL7P1.21
GO:0006342 chromatin silencing P
NAS
DmeFBgn0015270
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000264
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0015270
GO:0007076 mitotic chromosome condensation P
IMP
DmeFBgn0015270
GO:0007307 eggshell chorion gene amplification P
IMP
DmeFBgn0015270
TAS
DmeFBgn0015270
GO:0008283 cell proliferation P
IMP
DmeFBgn0015270
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00003882
GO:0010171 body morphogenesis P
IMP
CelWBGene00003882
GO:0016458 gene silencing P
RCA
SceS000000264
GO:0030261 chromosome condensation P
IMP
DmeFBgn0015270
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IDA
SceS000000264
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003882
GO:0040011 locomotion P
IMP
CelWBGene00003882
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00003882
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00003882
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00003882
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00003882
GO:0051568 histone H3-K4 methylation P
IMP
SceS000000264

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC685.09
(Q09142)
YBR060C
(S000000264)