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Search term: YBR080C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC18
SGD link S000000284
Alternative ID YBR080C
Description ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF
Synonyms YBR080C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0741 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING AAA+-type ATPase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g04910 GI:15234505
Caenorhabditis elegans (Cel) CE19925
(WBGene00003818)		 GI:17507923
Drosophila melanogaster (Dme) 7292852 GI:7292852
Drosophila melanogaster (Dme) 7299817 GI:7299817
Homo sapiens (Hsa) Hs11079228 GI:11079228
Homo sapiens (Hsa) Hs20559510 GI:20559510
Saccharomyces cerevisiae (Sce) YBR080c
(S000000284)		 GI:6319554 P18759
Schizosaccharomyces pombe (Spo) SPAC1834.11c GI:19115602 Q9P7Q4
Encephalitozoon cuniculi (Ecu) ECU03g1410 GI:19173098 Q8SS79
Arabidopsis thaliana (Ath) At4g04910 GI:15234505
Caenorhabditis elegans (Cel) CE19925
(WBGene00003818)		 GI:17507923
Drosophila melanogaster (Dme) 7292852 GI:7292852
Drosophila melanogaster (Dme) 7299817 GI:7299817
Homo sapiens (Hsa) Hs11079228 GI:11079228
Homo sapiens (Hsa) Hs20559510 GI:20559510
Saccharomyces cerevisiae (Sce) YBR080c
(S000000284)		 GI:6319554 P18759
Schizosaccharomyces pombe (Spo) SPAC1834.11c GI:19115602 Q9P7Q4
Encephalitozoon cuniculi (Ecu) ECU03g1410 GI:19173098 Q8SS79


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000284
SpoSPAC1834.11c
GO:0005773 vacuole C
IDA
AthAt4g04910
GO:0005794 Golgi apparatus C
RCA
SceS000000284
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000000284
GO:0031410 cytoplasmic vesicle C
RCA
SceS000000284
GO:0031982 vesicle C
RCA
SceS000000284
GO:0031988 membrane-bounded vesicle C
RCA
SceS000000284
GO:0043332 mating projection tip C
IDA
SceS000000284
GO:0044431 Golgi apparatus part C
RCA
SceS000000284
GO:0005515 protein binding F
IPI
AthAt4g04910
SpoSPAC1834.11c
GO:0005524 ATP binding F
ISS
SpoSPAC1834.11c
GO:0016887 ATPase activity F
IDA
SceS000000284
ISS
SpoSPAC1834.11c
GO:0000003 reproduction P
IMP
CelWBGene00003818
GO:0000045 autophagic vacuole assembly P
IMP
SceS000000284
GO:0002119 nematode larval development P
IMP
CelWBGene00003818
GO:0006200 ATP catabolic process P
ISS
SpoSPAC1834.11c
GO:0006886 intracellular protein transport P
IC
SpoSPAC1834.11c
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPAC1834.11c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00003818
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003818
GO:0016192 vesicle-mediated transport P
RCA
SceS000000284
GO:0032940 secretion by cell P
IMP
CelWBGene00003818
GO:0035494 SNARE complex disassembly P
IDA
SceS000000284
GO:0040007 growth P
IMP
CelWBGene00003818
GO:0040011 locomotion P
IMP
CelWBGene00003818
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000284
ISS
SpoSPAC1834.11c
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000000284
GO:0045184 establishment of protein localization P
RCA
SceS000000284
GO:0048211 Golgi vesicle docking P
IDA
SceS000000284
GO:0048219 inter-Golgi cisterna vesicle-mediated
transport		 P
IMP
SceS000000284
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000284

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4502

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NSF GI:156564401
Pan troglodytes (Ptr) NSF GI:114666582
Canis familiaris (Cfa) NSF GI:73965153
Mus musculus (Mmu) Nsf
(MGI:104560)		 GI:31543349 P46460
Rattus norvegicus (Rno) Nsf
(RGD:621594)		 GI:13489067
Gallus gallus (Gga) NSF GI:118102799
Drosophila melanogaster (Dme) Nsf2
(FBgn0013998)		 GI:28573010
Drosophila melanogaster (Dme) comt
(FBgn0000346)		 GI:17864540
Anopheles gambiae (Aga) AgaP_AGAP012684 GI:158284475
Caenorhabditis elegans (Cel) nsf-1
(CE19925;
WBGene00003818)		 GI:133901658
Schizosaccharomyces pombe (Spo) sec18
(SPAC1834.11c)		 GI:19115602 Q9P7Q4
Saccharomyces cerevisiae (Sce) SEC18
(S000000284)		 GI:6319554 P18759
Kluyveromyces lactis (Kla) KLLA0C14520g GI:50305779
Eremothecium gossypii (Ego) AGOS_AER169C GI:45190773
Magnaporthe grisea (Mgr) MGG_02418 GI:39968651
Neurospora crassa (Ncr) NCU03387.1 GI:32404064


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000284
SpoSPAC1834.11c
ISS
DmeFBgn0000346
FBgn0013998
NAS
DmeFBgn0013998
FBgn0000346
GO:0005794 Golgi apparatus C
RCA
SceS000000284
GO:0005829 cytosol C
EXP
HsaNSF
GO:0016023 cytoplasmic membrane-bounded vesicle C
RCA
SceS000000284
GO:0031410 cytoplasmic vesicle C
RCA
SceS000000284
GO:0031982 vesicle C
RCA
SceS000000284
GO:0031988 membrane-bounded vesicle C
RCA
SceS000000284
GO:0043198 dendritic shaft C
ISO
MmuMGI:104560
GO:0043332 mating projection tip C
IDA
SceS000000284
GO:0044431 Golgi apparatus part C
RCA
SceS000000284
GO:0005515 protein binding F
IPI
HsaNSF
MmuMGI:104560
SpoSPAC1834.11c
GO:0005524 ATP binding F
ISS
SpoSPAC1834.11c
GO:0008022 protein C-terminus binding F
ISO
MmuMGI:104560
GO:0016887 ATPase activity F
EXP
HsaNSF
IDA
SceS000000284
ISS
SpoSPAC1834.11c
TAS
DmeFBgn0000346
GO:0019905 syntaxin binding F
IDA
MmuMGI:104560
GO:0042623 ATPase activity, coupled F
IMP
MmuMGI:104560
GO:0000003 reproduction P
IMP
CelWBGene00003818
GO:0000045 autophagic vacuole assembly P
IMP
SceS000000284
GO:0002119 nematode larval development P
IMP
CelWBGene00003818
GO:0006200 ATP catabolic process P
IMP
MmuMGI:104560
ISS
SpoSPAC1834.11c
GO:0006813 potassium ion transport P
IDA
MmuMGI:104560
GO:0006886 intracellular protein transport P
IC
SpoSPAC1834.11c
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
DmeFBgn0013998
SpoSPAC1834.11c
NAS
DmeFBgn0000346
FBgn0013998
GO:0006891 intra-Golgi vesicle-mediated transport P
NAS
DmeFBgn0013998
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00003818
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0000346
GO:0007030 Golgi organization P
IMP
DmeFBgn0000346
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0013998
FBgn0000346
GO:0007274 neuromuscular synaptic transmission P
IMP
DmeFBgn0013998
GO:0008582 regulation of synaptic growth at neuromuscular
junction		 P
IMP
DmeFBgn0013998
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003818
GO:0015031 protein transport P
ISO
MmuMGI:104560
GO:0016082 synaptic vesicle priming P
NAS
DmeFBgn0000346
FBgn0013998
GO:0016192 vesicle-mediated transport P
ISO
MmuMGI:104560
NAS
DmeFBgn0013998
RCA
SceS000000284
GO:0017157 regulation of exocytosis P
ISO
MmuMGI:104560
GO:0032940 secretion by cell P
IMP
CelWBGene00003818
GO:0035494 SNARE complex disassembly P
IDA
SceS000000284
GO:0040007 growth P
IMP
CelWBGene00003818
GO:0040011 locomotion P
IMP
CelWBGene00003818
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000000284
ISS
SpoSPAC1834.11c
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000000284
GO:0045184 establishment of protein localization P
RCA
SceS000000284
GO:0048172 regulation of short-term neuronal synaptic
plasticity		 P
IDA
DmeFBgn0000346
GO:0048211 Golgi vesicle docking P
IDA
SceS000000284
GO:0048219 inter-Golgi cisterna vesicle-mediated
transport		 P
IMP
SceS000000284
GO:0048280 vesicle fusion with Golgi apparatus P
IDA
SceS000000284

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1844

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14159 ENSANGP00000012741
Ashbya gossypii (Ago) ago2672 AER169C
Arabidopsis thaliana (Ath) ath18374 At4g04910.1
Caenorhabditis elegans (Cel) cel11339 H15N14.2
Candida glabrata (Cgl) cgl1143 CAGL0E04642g
Candida glabrata (Cgl) cgl4732 CAGL0M01782g
Cryptococcus neoformans (Cne) cne1259 180.m00198
Dictyostelium discoideum (Ddi) ddi11851 DDB0185052
Debaryomyces hansenii (Dha) dha6194 DEHA0G11132g
Drosophila melanogaster (Dme) dme17668 CG1618-PA
(FBgn0000346)
Drosophila melanogaster (Dme) dme12499 CG33101-PA
(FBgn0013998)
Danio rerio (Dre) dre29134 ENSDARP00000000690
(si:bz18k17.1)
Encephalitozoon cuniculi (Ecu) ecu505 19173098
Takifugu rubripes (Fru) fru3586 SINFRUP00000139587
Takifugu rubripes (Fru) fru14984 SINFRUP00000147803
Takifugu rubripes (Fru) fru14983 SINFRUP00000171565
Gallus gallus (Gga) gga13770 ENSGALP00000001579
(NSF)
Homo sapiens (Hsa) hsa13889 ENSP00000225282
(NSF)		 B7Z5J7
Kluyveromyces lactis (Kla) kla1849 KLLA0C14520g
Mus musculus (Mmu) mmu4963 ENSMUSP00000048947
(MGI:104560)
Neurospora crassa (Ncr) ncr3284 NCU03387.2
Oryza sativa (Osa) osa63797 6631.m00161
Plasmodium falciparum (Pfa) pfa2683 PFC0140c
Rattus norvegicus (Rno) rno6263 ENSRNOP00000006361
(RGD:621594)		 Q9QUL6
Saccharomyces cerevisiae (Sce) sce336 YBR080C
(S000000284)
Schizosaccharomyces pombe (Spo) spo2683 SPAC1834.11c Q9P7Q4
Yarrowia lipolytica (Yli) yli5069 YALI0E29249g