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Search term: YBR088C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name POL30
SGD link S000000292
Alternative ID YBR088C
Description Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
Synonyms YBR088C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1636 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA polymerase delta processivity factor (proliferating cell nuclear antigen)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g07370 GI:15222379
Arabidopsis thaliana (Ath) At2g29570 GI:15227564
Caenorhabditis elegans (Cel) CE14512 GI:17541702
Drosophila melanogaster (Dme) 7298618 GI:7298618
Drosophila melanogaster (Dme) 7302405
(FBgn0005655)
GI:17136790
Homo sapiens (Hsa) Hs4505641
(PCNA)
GI:4505641 P12004
Saccharomyces cerevisiae (Sce) YBR088c
(S000000292)
GI:6319564 P15873
Schizosaccharomyces pombe (Spo) SPBC16D10.09 GI:19113296 Q03392
Encephalitozoon cuniculi (Ecu) ECU05g1030 GI:19173643 Q8SRV9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SpoSPBC16D10.09
IDA
AthAt1g07370
HsaPCNA
SceS000000292
SpoSPBC16D10.09
ISS
AthAt2g29570
At1g07370
GO:0005654 nucleoplasm C
EXP
HsaPCNA
GO:0005657 replication fork C
TAS
SceS000000292
GO:0005663 DNA replication factor C complex C
TAS
HsaPCNA
GO:0005730 nucleolus C
IDA
AthAt1g07370
GO:0005737 cytoplasm C
IDA
AthAt1g07370
GO:0005829 cytosol C
IDA
SpoSPBC16D10.09
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0005655
GO:0043596 nuclear replication fork C
IC
SpoSPBC16D10.09
IDA
HsaPCNA
GO:0043626 PCNA complex C
IMP
SpoSPBC16D10.09
ISS
DmeFBgn0005655
NAS
DmeFBgn0005655
TAS
SceS000000292
GO:0070557 PCNA-p21 complex C
IDA
HsaPCNA
GO:0000701 purine-specific mismatch base pair DNA
N-glycosylase activity
F
IDA
HsaPCNA
GO:0003677 DNA binding F
ISS
AthAt1g07370
At2g29570
GO:0005515 protein binding F
IPI
AthAt1g07370
HsaPCNA
SpoSPBC16D10.09
GO:0030337 DNA polymerase processivity factor
activity
F
IDA
SceS000000292
ISS
AthAt2g29570
At1g07370
SpoSPBC16D10.09
GO:0032139 dinucleotide insertion or deletion
binding
F
IDA
HsaPCNA
GO:0032405 MutLalpha complex binding F
IDA
HsaPCNA
GO:0000710 meiotic mismatch repair P
IGI
SceS000000292
IMP
SceS000000292
GO:0006260 DNA replication P
IMP
DmeFBgn0005655
NAS
HsaPCNA
RCA
SceS000000292
TAS
DmeFBgn0005655
GO:0006261 DNA-dependent DNA replication P
TAS
DmeFBgn0005655
GO:0006271 DNA strand elongation involved in DNA
replication
P
IC
SpoSPBC16D10.09
GO:0006272 leading strand elongation P
IDA
SceS000000292
NAS
DmeFBgn0005655
GO:0006273 lagging strand elongation P
IDA
SceS000000292
IPI
SceS000000292
GO:0006275 regulation of DNA replication P
ISS
AthAt2g29570
At1g07370
GO:0006281 DNA repair P
NAS
HsaPCNA
RCA
SceS000000292
GO:0006284 base-excision repair P
TAS
SceS000000292
GO:0006289 nucleotide-excision repair P
IMP
SceS000000292
TAS
DmeFBgn0005655
GO:0006297 nucleotide-excision repair, DNA gap
filling
P
EXP
HsaPCNA
GO:0006298 mismatch repair P
IDA
HsaPCNA
IMP
SceS000000292
IPI
SceS000000292
TAS
DmeFBgn0005655
GO:0006301 postreplication repair P
IGI
SpoSPBC16D10.09
IMP
SceS000000292
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000292
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000292
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0005655
GO:0007064 mitotic sister chromatid cohesion P
IGI
SceS000000292
IPI
SceS000000292
GO:0007307 eggshell chorion gene amplification P
TAS
DmeFBgn0005655
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC16D10.09
GO:0008283 cell proliferation P
TAS
HsaPCNA
GO:0010212 response to ionizing radiation P
IMP
SpoSPBC16D10.09
GO:0019730 antimicrobial humoral response P
IMP
DmeFBgn0005655
GO:0019985 translesion synthesis P
IDA
HsaPCNA
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IMP
SceS000000292
GO:0034644 cellular response to UV P
IMP
SpoSPBC16D10.09
GO:0042276 error-prone translesion synthesis P
IDA
AthAt2g29570
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaPCNA
GO:0051726 regulation of cell cycle P
ISS
AthAt1g07370

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1945

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PCNA GI:4505641 P12004
Pan troglodytes (Ptr) PCNA GI:114680824
Canis familiaris (Cfa) PCNA GI:73991708
Mus musculus (Mmu) Pcna
(MGI:97503)
GI:7242171 P17918
Rattus norvegicus (Rno) Pcna
(RGD:3269)
GI:11693142 44474
Gallus gallus (Gga) PCNA GI:45383776
Drosophila melanogaster (Dme) mus209
(FBgn0005655)
GI:17136790
Anopheles gambiae (Aga) AgaP_AGAP010220 GI:58392487
Schizosaccharomyces pombe (Spo) pcn GI:19113296
Saccharomyces cerevisiae (Sce) POL30
(S000000292)
GI:6319564 P15873
Kluyveromyces lactis (Kla) KLLA0B12078g GI:50304235
Eremothecium gossypii (Ego) AGOS_ADL309W GI:45187564
Magnaporthe grisea (Mgr) MGG_00518 GI:145611276
Neurospora crassa (Ncr) NCU09239.1 GI:32422375
Arabidopsis thaliana (Ath) PCNA2 GI:15227564
Arabidopsis thaliana (Ath) PCNA1 GI:15222379
Oryza sativa (Osa) Os02g0805200 GI:115449323
Plasmodium falciparum (Pfa) PF13_0328 GI:124513948


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000307 cyclin-dependent protein kinase holoenzyme
complex
C
IPI
MmuMGI:97503
GO:0005634 nucleus C
IDA
AthPCNA1
HsaPCNA
MmuMGI:97503
SceS000000292
ISO
MmuMGI:97503
ISS
AthPCNA2
PCNA1
MmuMGI:97503
GO:0005652 nuclear lamina C
IDA
MmuMGI:97503
GO:0005654 nucleoplasm C
EXP
HsaPCNA
GO:0005657 replication fork C
IDA
MmuMGI:97503
TAS
SceS000000292
GO:0005663 DNA replication factor C complex C
TAS
HsaPCNA
GO:0005730 nucleolus C
IDA
AthPCNA1
GO:0005737 cytoplasm C
IDA
AthPCNA1
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0005655
GO:0043596 nuclear replication fork C
IDA
HsaPCNA
GO:0043626 PCNA complex C
ISS
DmeFBgn0005655
NAS
DmeFBgn0005655
TAS
SceS000000292
GO:0070557 PCNA-p21 complex C
IDA
HsaPCNA
GO:0000701 purine-specific mismatch base pair DNA
N-glycosylase activity
F
IDA
HsaPCNA
GO:0003677 DNA binding F
ISS
AthPCNA1
PCNA2
GO:0005515 protein binding F
IPI
AthPCNA1
HsaPCNA
MmuMGI:97503
GO:0030337 DNA polymerase processivity factor
activity
F
IDA
SceS000000292
ISS
AthPCNA2
PCNA1
GO:0032139 dinucleotide insertion or deletion
binding
F
IDA
HsaPCNA
GO:0032405 MutLalpha complex binding F
IDA
HsaPCNA
GO:0000710 meiotic mismatch repair P
IGI
SceS000000292
IMP
SceS000000292
GO:0006260 DNA replication P
IMP
DmeFBgn0005655
NAS
HsaPCNA
RCA
SceS000000292
TAS
DmeFBgn0005655
GO:0006261 DNA-dependent DNA replication P
TAS
DmeFBgn0005655
GO:0006272 leading strand elongation P
IDA
SceS000000292
NAS
DmeFBgn0005655
GO:0006273 lagging strand elongation P
IDA
SceS000000292
IPI
SceS000000292
GO:0006275 regulation of DNA replication P
ISS
AthPCNA2
PCNA1
GO:0006281 DNA repair P
NAS
HsaPCNA
RCA
SceS000000292
GO:0006284 base-excision repair P
TAS
SceS000000292
GO:0006287 base-excision repair, gap-filling P
IDA
MmuMGI:97503
GO:0006289 nucleotide-excision repair P
IMP
SceS000000292
TAS
DmeFBgn0005655
GO:0006297 nucleotide-excision repair, DNA gap
filling
P
EXP
HsaPCNA
GO:0006298 mismatch repair P
IDA
HsaPCNA
IMP
SceS000000292
IPI
SceS000000292
TAS
DmeFBgn0005655
GO:0006301 postreplication repair P
IMP
SceS000000292
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000292
GO:0006886 intracellular protein transport P
IMP
MmuMGI:97503
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000292
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0005655
GO:0007064 mitotic sister chromatid cohesion P
IGI
SceS000000292
IPI
SceS000000292
GO:0007307 eggshell chorion gene amplification P
TAS
DmeFBgn0005655
GO:0008283 cell proliferation P
TAS
HsaPCNA
GO:0019730 antimicrobial humoral response P
IMP
DmeFBgn0005655
GO:0019985 translesion synthesis P
IDA
HsaPCNA
GO:0030466 chromatin silencing at silent mating-type
cassette
P
IMP
SceS000000292
GO:0033993 response to lipid P
ISO
MmuMGI:97503
GO:0042276 error-prone translesion synthesis P
IDA
AthPCNA2
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaPCNA
GO:0051726 regulation of cell cycle P
ISS
AthPCNA1

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