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Search term: YBR091C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIM12
SGD link S000000295
Alternative ID YBR091C
Description Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
Synonyms YBR091C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3480 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Mitochondrial import inner membrane translocase, subunits TIM10/TIM12

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g29530 GI:18402072
Caenorhabditis elegans (Cel) CE28800
(WBGene00006573)		 GI:17556370 Q9Y0V6
Drosophila melanogaster (Dme) 7291327
(FBgn0027360)		 GI:19922708
Homo sapiens (Hsa) Hs6912708
(TIMM10)		 GI:6912708 P62072
Saccharomyces cerevisiae (Sce) YBR091c
(S000000295)		 GI:6319567 P32830
Saccharomyces cerevisiae (Sce) YHR005c-a
(S000003530)		 GI:6321793 P87108
Schizosaccharomyces pombe (Spo) SPAC222.03c GI:19114054 Q9UTE9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.03c
GO:0005739 mitochondrion C
IDA
AthAt2g29530
SceS000000295
S000003530
GO:0005743 mitochondrial inner membrane C
ISS
AthAt2g29530
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
ISS
DmeFBgn0027360
NAS
DmeFBgn0027360
TAS
HsaTIMM10
GO:0005758 mitochondrial intermembrane space C
IDA
AthAt2g29530
ISS
SpoSPAC222.03c
GO:0005829 cytosol C
IDA
SpoSPAC222.03c
GO:0042719 mitochondrial intermembrane space protein
transporter complex		 C
IDA
SceS000003530
ISS
SpoSPAC222.03c
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
IDA
SceS000003530
S000000295
GO:0005543 phospholipid binding F
IDA
SceS000000295
IMP
SceS000000295
GO:0008270 zinc ion binding F
TAS
HsaTIMM10
GO:0008565 protein transporter activity F
IDA
SceS000003530
IMP
SceS000003530
ISS
SpoSPAC222.03c
GO:0015266 protein channel activity F
IDA
SceS000000295
IMP
SceS000000295
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISS
AthAt2g29530
DmeFBgn0027360
NAS
DmeFBgn0027360
GO:0051082 unfolded protein binding F
IDA
SceS000003530
GO:0006626 protein targeting to mitochondrion P
ISS
AthAt2g29530
DmeFBgn0027360
TAS
HsaTIMM10
GO:0006839 mitochondrial transport P
RCA
SceS000003530
S000000295
GO:0007605 sensory perception of sound P
TAS
HsaTIMM10
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006573
GO:0015031 protein transport P
NAS
DmeFBgn0027360
GO:0040007 growth P
IMP
CelWBGene00006573
GO:0040011 locomotion P
IMP
CelWBGene00006573
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00006573
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00006573
GO:0045039 protein import into mitochondrial inner
membrane		 P
IDA
SceS000000295
S000003530
IMP
SceS000003530
S000000295
ISS
SpoSPAC222.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38409

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MRS5 GI:6319567 P32830
Kluyveromyces lactis (Kla) KLLA0B12034g GI:50304231
Eremothecium gossypii (Ego) AGOS_ADL311W GI:45187562


GO terms for Homologene results:

None found.

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2011

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7637 ENSANGP00000016855
Ashbya gossypii (Ago) ago1430 ADL311W
Ashbya gossypii (Ago) ago1897 ADR155C
Arabidopsis thaliana (Ath) ath9922 At2g29530.1
Caenorhabditis elegans (Cel) cel20321 Y66D12A.22
(CE28800;
WBGene00006573)
Candida glabrata (Cgl) cgl2437 CAGL0H08525g
Cryptococcus neoformans (Cne) cne557 163.m06439
Dictyostelium discoideum (Ddi) ddi7698 DDB0186253
Debaryomyces hansenii (Dha) dha3162 DEHA0D19305g
Debaryomyces hansenii (Dha) dha6563 DEHA0G19283g
Drosophila melanogaster (Dme) dme6405 CG9878-PA
(FBgn0027360)
Drosophila melanogaster (Dme) dme6406 CG9878-PB
(FBgn0027360)
Danio rerio (Dre) dre30213 ENSDARP00000038710
(zgc:86900)		 Q6DI06
Takifugu rubripes (Fru) fru3549 SINFRUP00000138789
Gallus gallus (Gga) gga25230 ENSGALP00000007724
(TIMM10)
Homo sapiens (Hsa) hsa5625 ENSP00000257245
(TIMM10)		 P62072
Kluyveromyces lactis (Kla) kla1063 KLLA0B12034g
Kluyveromyces lactis (Kla) kla5232 KLLA0F25872g
Mus musculus (Mmu) mmu14902 ENSMUSP00000028470
(MGI:1353429)		 P62073
Neurospora crassa (Ncr) ncr904 NCU00930.2
Oryza sativa (Osa) osa1516 1588.m00148
Oryza sativa (Osa) osa43972 5316.m00171
Plasmodium falciparum (Pfa) pfa4872 PFL0430w
Rattus norvegicus (Rno) rno18913 ENSRNOP00000010619
(RGD:621741)		 P62074
Saccharomyces cerevisiae (Sce) sce350 YBR091C
(S000000295)
Saccharomyces cerevisiae (Sce) sce2750 YHR005C-A
(S000003530)
Schizosaccharomyces pombe (Spo) spo3740 SPAC222.03c Q9UTE9
Yarrowia lipolytica (Yli) yli2586 YALI0C21780g
Yarrowia lipolytica (Yli) yli4125 YALI0E06237g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.03c
GO:0005739 mitochondrion C
IDA
AthAt2g29530
MmuMGI:1353429
SceS000000295
S000003530
GO:0005743 mitochondrial inner membrane C
ISS
AthAt2g29530
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
ISS
DmeFBgn0027360
PfaPFL0430w
NAS
DmeFBgn0027360
GO:0005758 mitochondrial intermembrane space C
IDA
AthAt2g29530
ISS
SpoSPAC222.03c
GO:0005829 cytosol C
IDA
SpoSPAC222.03c
GO:0042719 mitochondrial intermembrane space protein
transporter complex		 C
IDA
SceS000003530
ISS
SpoSPAC222.03c
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
IDA
SceS000003530
S000000295
GO:0005543 phospholipid binding F
IDA
SceS000000295
IMP
SceS000000295
GO:0008565 protein transporter activity F
IDA
SceS000003530
IMP
SceS000003530
ISS
SpoSPAC222.03c
GO:0015266 protein channel activity F
IDA
SceS000000295
IMP
SceS000000295
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISS
AthAt2g29530
DmeFBgn0027360
PfaPFL0430w
NAS
DmeFBgn0027360
GO:0051082 unfolded protein binding F
IDA
SceS000003530
GO:0006626 protein targeting to mitochondrion P
ISS
AthAt2g29530
DmeFBgn0027360
PfaPFL0430w
GO:0006839 mitochondrial transport P
RCA
SceS000003530
S000000295
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006573
GO:0015031 protein transport P
ISS
PfaPFL0430w
NAS
DmeFBgn0027360
GO:0040007 growth P
IMP
CelWBGene00006573
GO:0040011 locomotion P
IMP
CelWBGene00006573
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00006573
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00006573
GO:0045039 protein import into mitochondrial inner
membrane		 P
IDA
SceS000000295
S000003530
IMP
SceS000003530
S000000295
ISS
SpoSPAC222.03c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC222.03c
(Q9UTE9)		 YBR091C
(S000000295)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.03c
GO:0005739 mitochondrion C
IDA
SceS000000295
GO:0005758 mitochondrial intermembrane space C
ISS
SpoSPAC222.03c
GO:0005829 cytosol C
IDA
SpoSPAC222.03c
GO:0042719 mitochondrial intermembrane space protein
transporter complex		 C
ISS
SpoSPAC222.03c
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
IDA
SceS000000295
GO:0005543 phospholipid binding F
IDA
SceS000000295
IMP
SceS000000295
GO:0008565 protein transporter activity F
ISS
SpoSPAC222.03c
GO:0015266 protein channel activity F
IDA
SceS000000295
IMP
SceS000000295
GO:0006839 mitochondrial transport P
RCA
SceS000000295
GO:0045039 protein import into mitochondrial inner
membrane		 P
IDA
SceS000000295
IMP
SceS000000295
ISS
SpoSPAC222.03c

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GO info in one table:

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