YOGY Home YOGY Help

Search term: YBR103W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SIF2
SGD link S000000307
Alternative ID YBR103W
Description WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
Synonyms YBR103W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0273 A-DHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Beta-transducin family (WD-40 repeat) protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g67320 GI:15240710
Drosophila melanogaster (Dme) 7296209
(FBgn0023444)		 GI:17137500
Homo sapiens (Hsa) Hs5032159 GI:5032159 O60907
Homo sapiens (Hsa) Hs15150805
(TBL1Y)		 GI:15150805 Q9BQ87
Homo sapiens (Hsa) Hs19913371
(TBL1XR1)		 GI:19913371 Q9BZK7
Saccharomyces cerevisiae (Sce) YBR103w
(S000000307)		 GI:6319579 P38262
Schizosaccharomyces pombe (Spo) SPCC1235.09 GI:19075235 O74845
Encephalitozoon cuniculi (Ecu) ECU01g0980 GI:19075109
Arabidopsis thaliana (Ath) At5g67320 GI:15240710
Drosophila melanogaster (Dme) 7296209
(FBgn0023444)		 GI:17137500
Homo sapiens (Hsa) Hs5032159 GI:5032159 O60907
Homo sapiens (Hsa) Hs15150805
(TBL1Y)		 GI:15150805 Q9BQ87
Homo sapiens (Hsa) Hs19913371
(TBL1XR1)		 GI:19913371 Q9BZK7
Saccharomyces cerevisiae (Sce) YBR103w
(S000000307)		 GI:6319579 P38262
Schizosaccharomyces pombe (Spo) SPCC1235.09 GI:19075235 O74845
Encephalitozoon cuniculi (Ecu) ECU01g0980 GI:19075109
Arabidopsis thaliana (Ath) At5g67320 GI:15240710
Drosophila melanogaster (Dme) 7296209
(FBgn0023444)		 GI:17137500
Homo sapiens (Hsa) Hs5032159 GI:5032159 O60907
Homo sapiens (Hsa) Hs15150805
(TBL1Y)		 GI:15150805 Q9BQ87
Homo sapiens (Hsa) Hs19913371
(TBL1XR1)		 GI:19913371 Q9BZK7
Saccharomyces cerevisiae (Sce) YBR103w
(S000000307)		 GI:6319579 P38262
Schizosaccharomyces pombe (Spo) SPCC1235.09 GI:19075235 O74845
Encephalitozoon cuniculi (Ecu) ECU01g0980 GI:19075109


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000118 histone deacetylase complex C
IDA
HsaTBL1XR1
GO:0005634 nucleus C
IDA
AthAt5g67320
DmeFBgn0023444
HsaTBL1XR1
SceS000000307
SpoSPCC1235.09
GO:0005829 cytosol C
IDA
SpoSPCC1235.09
GO:0005834 heterotrimeric G-protein complex C
ISS
AthAt5g67320
GO:0005876 spindle microtubule C
IDA
HsaTBL1XR1
GO:0017053 transcriptional repressor complex C
IDA
HsaTBL1XR1
GO:0034967 Set3 complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0070210 Rpd3L-Expanded complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g67320
GO:0003674 molecular_function F
ND
SceS000000307
SpoSPCC1235.09
GO:0003714 transcription corepressor activity F
IDA
HsaTBL1XR1
IGI
HsaTBL1XR1
GO:0005515 protein binding F
IPI
DmeFBgn0023444
HsaTBL1XR1
GO:0005525 GTP binding F
ISS
DmeFBgn0023444
GO:0008013 beta-catenin binding F
IPI
HsaTBL1XR1
GO:0010843 promoter binding F
IDA
HsaTBL1XR1
ISS
HsaTBL1XR1
GO:0016563 transcription activator activity F
IDA
HsaTBL1XR1
GO:0042393 histone binding F
IDA
HsaTBL1XR1
GO:0047485 protein N-terminus binding F
IPI
HsaTBL1XR1
GO:0006338 chromatin remodeling P
IC
SpoSPCC1235.09
GO:0006342 chromatin silencing P
ISS
SpoSPCC1235.09
GO:0007173 epidermal growth factor receptor signaling
pathway		 P
TAS
DmeFBgn0023444
GO:0007219 Notch signaling pathway P
TAS
DmeFBgn0023444
GO:0009409 response to cold P
IMP
AthAt5g67320
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter		 P
IDA
HsaTBL1XR1
ISS
SpoSPCC1235.09
GO:0016575 histone deacetylation P
IDA
SceS000000307
IMP
AthAt5g67320
ISS
SpoSPCC1235.09
GO:0030162 regulation of proteolysis P
TAS
DmeFBgn0023444
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000307
GO:0031939 negative regulation of chromatin silencing at
telomere		 P
IMP
SceS000000307
IPI
SceS000000307
GO:0032874 positive regulation of stress-activated MAPK
cascade		 P
IMP
SceS000000307
GO:0042058 regulation of epidermal growth factor receptor
signaling pathway		 P
IMP
DmeFBgn0023444
GO:0042676 compound eye cone cell fate commitment P
TAS
DmeFBgn0023444
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
ISS
HsaTBL1XR1
GO:0045449 regulation of transcription P
IMP
SceS000000307
GO:0045835 negative regulation of meiosis P
IPI
SceS000000307
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IDA
HsaTBL1XR1
GO:0051726 regulation of cell cycle P
IMP
DmeFBgn0023444
GO:0060070 canonical Wnt receptor signaling
pathway		 P
IMP
HsaTBL1XR1

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101554

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SIF2
(S000000307)		 GI:6319579 P38262
Kluyveromyces lactis (Kla) KLLA0E11297g GI:50308909
Eremothecium gossypii (Ego) AGOS_ADL322C GI:45187551


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000307
GO:0034967 Set3 complex C
IDA
SceS000000307
GO:0070210 Rpd3L-Expanded complex C
IDA
SceS000000307
GO:0003674 molecular_function F
ND
SceS000000307
GO:0016575 histone deacetylation P
IDA
SceS000000307
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000307
GO:0031939 negative regulation of chromatin silencing at
telomere		 P
IMP
SceS000000307
IPI
SceS000000307
GO:0032874 positive regulation of stress-activated MAPK
cascade		 P
IMP
SceS000000307
GO:0045449 regulation of transcription P
IMP
SceS000000307
GO:0045835 negative regulation of meiosis P
IPI
SceS000000307

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2491

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9645 ENSANGP00000022244
Ashbya gossypii (Ago) ago1419 ADL322C
Arabidopsis thaliana (Ath) ath28916 At5g67320.1
Candida glabrata (Cgl) cgl4042 CAGL0K12188g
Cryptococcus neoformans (Cne) cne458 163.m06380
Dictyostelium discoideum (Ddi) ddi4985 DDB0206475
Debaryomyces hansenii (Dha) dha5138 DEHA0F16874g
Drosophila melanogaster (Dme) dme92 CG4063-PA
(FBgn0023444)
Danio rerio (Dre) dre25129 ENSDARP00000023370
Danio rerio (Dre) dre20232 ENSDARP00000033337
Danio rerio (Dre) dre2406 ENSDARP00000035988
Takifugu rubripes (Fru) fru16094 SINFRUP00000141879
Takifugu rubripes (Fru) fru29966 SINFRUP00000144793
Takifugu rubripes (Fru) fru4533 SINFRUP00000164449
Gallus gallus (Gga) gga26405 ENSGALP00000021770
(TBL1X)
Gallus gallus (Gga) gga26830 ENSGALP00000022412
(RCJMB04_8j10)		 Q5ZKZ7
Homo sapiens (Hsa) hsa32421 ENSP00000217964
(TBL1X)		 O60907-1
Homo sapiens (Hsa) hsa23482 ENSP00000263964
(TBL1XR1)		 C9IYU9
Homo sapiens (Hsa) hsa23481 ENSP00000348034
Kluyveromyces lactis (Kla) kla3459 KLLA0E11297g
Mus musculus (Mmu) mmu29211 ENSMUSP00000026275
Mus musculus (Mmu) mmu16419 ENSMUSP00000067277
(MGI:2441730)		 Q8BHJ5
Neurospora crassa (Ncr) ncr6652 NCU06838.2
Oryza sativa (Osa) osa68109 6901.m00147
Rattus norvegicus (Rno) rno31422 ENSRNOP00000004901
(RGD:1563868)		 B2RZA6
Rattus norvegicus (Rno) rno15848 ENSRNOP00000015573
(RGD:1560053)
Saccharomyces cerevisiae (Sce) sce362 YBR103W
(S000000307)
Schizosaccharomyces pombe (Spo) spo817 SPCC1235.09 O74845
Yarrowia lipolytica (Yli) yli5811 YALI0F11165g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
MmuMGI:2441730
IDA
AthAt5g67320
DmeFBgn0023444
SceS000000307
SpoSPCC1235.09
GO:0005829 cytosol C
IDA
SpoSPCC1235.09
GO:0005834 heterotrimeric G-protein complex C
ISS
AthAt5g67320
GO:0034967 Set3 complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0070210 Rpd3L-Expanded complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt5g67320
GO:0003674 molecular_function F
ND
SceS000000307
SpoSPCC1235.09
GO:0003677 DNA binding F
IDA
MmuMGI:2441730
GO:0003714 transcription corepressor activity F
IMP
MmuMGI:2441730
GO:0005515 protein binding F
IPI
DmeFBgn0023444
MmuMGI:2441730
GO:0005525 GTP binding F
ISS
DmeFBgn0023444
GO:0010843 promoter binding F
IDA
MmuMGI:2441730
GO:0006338 chromatin remodeling P
IC
SpoSPCC1235.09
GO:0006342 chromatin silencing P
ISS
SpoSPCC1235.09
GO:0007173 epidermal growth factor receptor signaling
pathway		 P
TAS
DmeFBgn0023444
GO:0007219 Notch signaling pathway P
TAS
DmeFBgn0023444
GO:0009409 response to cold P
IMP
AthAt5g67320
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter		 P
ISS
SpoSPCC1235.09
GO:0016575 histone deacetylation P
IDA
SceS000000307
IMP
AthAt5g67320
ISS
SpoSPCC1235.09
GO:0030162 regulation of proteolysis P
TAS
DmeFBgn0023444
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000307
GO:0031939 negative regulation of chromatin silencing at
telomere		 P
IMP
SceS000000307
IPI
SceS000000307
GO:0032874 positive regulation of stress-activated MAPK
cascade		 P
IMP
SceS000000307
GO:0042058 regulation of epidermal growth factor receptor
signaling pathway		 P
IMP
DmeFBgn0023444
GO:0042676 compound eye cone cell fate commitment P
TAS
DmeFBgn0023444
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IMP
MmuMGI:2441730
GO:0045449 regulation of transcription P
IMP
SceS000000307
GO:0045835 negative regulation of meiosis P
IPI
SceS000000307
GO:0045892 negative regulation of transcription,
DNA-dependent		 P
IMP
MmuMGI:2441730
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
MmuMGI:2441730
GO:0051726 regulation of cell cycle P
IMP
DmeFBgn0023444

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1235.09
(O74845)		 YBR103W
(S000000307)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000307
SpoSPCC1235.09
GO:0005829 cytosol C
IDA
SpoSPCC1235.09
GO:0034967 Set3 complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0070210 Rpd3L-Expanded complex C
IDA
SceS000000307
SpoSPCC1235.09
GO:0003674 molecular_function F
ND
SceS000000307
SpoSPCC1235.09
GO:0006338 chromatin remodeling P
IC
SpoSPCC1235.09
GO:0006342 chromatin silencing P
ISS
SpoSPCC1235.09
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter		 P
ISS
SpoSPCC1235.09
GO:0016575 histone deacetylation P
IDA
SceS000000307
ISS
SpoSPCC1235.09
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000000307
GO:0031939 negative regulation of chromatin silencing at
telomere		 P
IMP
SceS000000307
IPI
SceS000000307
GO:0032874 positive regulation of stress-activated MAPK
cascade		 P
IMP
SceS000000307
GO:0045449 regulation of transcription P
IMP
SceS000000307
GO:0045835 negative regulation of meiosis P
IPI
SceS000000307

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk