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Search term: YBR175W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SWD3
SGD link S000000379
Alternative ID YBR175W
Description Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5
Synonyms YBR175W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0266 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED WD40 repeat-containing protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g04140 GI:15219663
Arabidopsis thaliana (Ath) At1g15750 GI:18394279
Arabidopsis thaliana (Ath) At1g80490 GI:15220148
Arabidopsis thaliana (Ath) At2g25420 GI:15224724
Arabidopsis thaliana (Ath) At2g32700 GI:18403052
Arabidopsis thaliana (Ath) At3g15880 GI:15233223
Arabidopsis thaliana (Ath) At3g16830 GI:15228877
Arabidopsis thaliana (Ath) At3g49660 GI:15229187
Arabidopsis thaliana (Ath) At4g02730 GI:15235470
Arabidopsis thaliana (Ath) At4g03020 GI:15236235
Arabidopsis thaliana (Ath) At4g32551 GI:7486768
Arabidopsis thaliana (Ath) At5g27030 GI:15240430
Arabidopsis thaliana (Ath) At5g43930 GI:15240053
Caenorhabditis elegans (Cel) CE00901
(WBGene00006474)
GI:17552164 Q17963
Caenorhabditis elegans (Cel) CE06574
(WBGene00013862)
GI:17566626
Caenorhabditis elegans (Cel) CE09086
(WBGene00008419)
GI:17506395 P90794
Caenorhabditis elegans (Cel) CE11748
(WBGene00010572)
GI:17568701 Q93847
Caenorhabditis elegans (Cel) CE23620 GI:17506397 P90794
Caenorhabditis elegans (Cel) CE28982
(WBGene00021467)
GI:17509921 Q95XR3
Drosophila melanogaster (Dme) 7290331
(FBgn0040066)
GI:17864654
Drosophila melanogaster (Dme) 7295309 GI:7295309 Q9VS00
Drosophila melanogaster (Dme) 7301300 GI:7301300
Drosophila melanogaster (Dme) 7302357 GI:7302357
Drosophila melanogaster (Dme) 7302720 GI:7302720
Homo sapiens (Hsa) Hs13129028 GI:13129028
Homo sapiens (Hsa) Hs13376751
(PAAF1)
GI:13376751 Q9BRP4
Homo sapiens (Hsa) Hs16445426
(WDR13)
GI:16445426 Q14827
Homo sapiens (Hsa) Hs16554627 GI:16554627 Q9H7J6
Homo sapiens (Hsa) Hs18565451 GI:18565451
Homo sapiens (Hsa) Hs18599360 GI:18599360
Homo sapiens (Hsa) Hs18677720
(WSB1)
GI:18677720 Q9Y656
Homo sapiens (Hsa) Hs20127645 GI:20127645
Homo sapiens (Hsa) Hs20143910 GI:20143910
Homo sapiens (Hsa) Hs20143912 GI:20143912 Q9Y656
Homo sapiens (Hsa) Hs21361641 GI:12053107 Q9NXT1
Homo sapiens (Hsa) Hs21450820 GI:19263503 Q8N1V2
Homo sapiens (Hsa) Hs21686975 GI:15278250
Homo sapiens (Hsa) Hs22046076 GI:22046076
Homo sapiens (Hsa) Hs22048015 GI:18676859 Q9H5C9
Homo sapiens (Hsa) Hs22052079 GI:22052079
Homo sapiens (Hsa) Hs8923273_1 GI:8923273
Homo sapiens (Hsa) Hs8923881
(WSB2)
GI:8923881 Q9NYS7
Homo sapiens (Hsa) Hs9506645 GI:9506645
Homo sapiens (Hsa) HsM8923075 GI:8923075
Saccharomyces cerevisiae (Sce) YBR175w
(S000000379)
GI:6319651 P38123
Saccharomyces cerevisiae (Sce) YCR084c
(S000000680)
GI:6319926 P16649
Saccharomyces cerevisiae (Sce) YGL004c
(S000002972)
GI:6321434 P53196
Schizosaccharomyces pombe (Spo) SPAC18B11.10 GI:19113785 Q09715
Schizosaccharomyces pombe (Spo) SPAC630.14c GI:19113822 Q9UUG8
Schizosaccharomyces pombe (Spo) SPBC354.03 GI:19112019 O43017
Arabidopsis thaliana (Ath) At1g04140 GI:15219663
Arabidopsis thaliana (Ath) At1g15750 GI:18394279
Arabidopsis thaliana (Ath) At1g80490 GI:15220148
Arabidopsis thaliana (Ath) At2g25420 GI:15224724
Arabidopsis thaliana (Ath) At2g32700 GI:18403052
Arabidopsis thaliana (Ath) At3g15880 GI:15233223
Arabidopsis thaliana (Ath) At3g16830 GI:15228877
Arabidopsis thaliana (Ath) At3g49660 GI:15229187
Arabidopsis thaliana (Ath) At4g02730 GI:15235470
Arabidopsis thaliana (Ath) At4g03020 GI:15236235
Arabidopsis thaliana (Ath) At4g32551 GI:7486768
Arabidopsis thaliana (Ath) At5g27030 GI:15240430
Arabidopsis thaliana (Ath) At5g43930 GI:15240053
Caenorhabditis elegans (Cel) CE00901
(WBGene00006474)
GI:17552164 Q17963
Caenorhabditis elegans (Cel) CE06574
(WBGene00013862)
GI:17566626
Caenorhabditis elegans (Cel) CE09086
(WBGene00008419)
GI:17506395 P90794
Caenorhabditis elegans (Cel) CE11748
(WBGene00010572)
GI:17568701 Q93847
Caenorhabditis elegans (Cel) CE23620 GI:17506397 P90794
Caenorhabditis elegans (Cel) CE28982
(WBGene00021467)
GI:17509921 Q95XR3
Drosophila melanogaster (Dme) 7290331
(FBgn0040066)
GI:17864654
Drosophila melanogaster (Dme) 7295309 GI:7295309 Q9VS00
Drosophila melanogaster (Dme) 7301300 GI:7301300
Drosophila melanogaster (Dme) 7302357 GI:7302357
Drosophila melanogaster (Dme) 7302720 GI:7302720
Homo sapiens (Hsa) Hs13129028 GI:13129028
Homo sapiens (Hsa) Hs13376751
(PAAF1)
GI:13376751 Q9BRP4
Homo sapiens (Hsa) Hs16445426
(WDR13)
GI:16445426 Q14827
Homo sapiens (Hsa) Hs16554627 GI:16554627 Q9H7J6
Homo sapiens (Hsa) Hs18565451 GI:18565451
Homo sapiens (Hsa) Hs18599360 GI:18599360
Homo sapiens (Hsa) Hs18677720
(WSB1)
GI:18677720 Q9Y656
Homo sapiens (Hsa) Hs20127645 GI:20127645
Homo sapiens (Hsa) Hs20143910 GI:20143910
Homo sapiens (Hsa) Hs20143912 GI:20143912 Q9Y656
Homo sapiens (Hsa) Hs21361641 GI:12053107 Q9NXT1
Homo sapiens (Hsa) Hs21450820 GI:19263503 Q8N1V2
Homo sapiens (Hsa) Hs21686975 GI:15278250
Homo sapiens (Hsa) Hs22046076 GI:22046076
Homo sapiens (Hsa) Hs22048015 GI:18676859 Q9H5C9
Homo sapiens (Hsa) Hs22052079 GI:22052079
Homo sapiens (Hsa) Hs8923273_1 GI:8923273
Homo sapiens (Hsa) Hs8923881
(WSB2)
GI:8923881 Q9NYS7
Homo sapiens (Hsa) Hs9506645 GI:9506645
Homo sapiens (Hsa) HsM8923075 GI:8923075
Saccharomyces cerevisiae (Sce) YBR175w
(S000000379)
GI:6319651 P38123
Saccharomyces cerevisiae (Sce) YCR084c
(S000000680)
GI:6319926 P16649
Saccharomyces cerevisiae (Sce) YGL004c
(S000002972)
GI:6321434 P53196
Schizosaccharomyces pombe (Spo) SPAC18B11.10 GI:19113785 Q09715
Schizosaccharomyces pombe (Spo) SPAC630.14c GI:19113822 Q9UUG8
Schizosaccharomyces pombe (Spo) SPBC354.03 GI:19112019 O43017
Arabidopsis thaliana (Ath) At1g04140 GI:15219663
Arabidopsis thaliana (Ath) At1g15750 GI:18394279
Arabidopsis thaliana (Ath) At1g80490 GI:15220148
Arabidopsis thaliana (Ath) At2g25420 GI:15224724
Arabidopsis thaliana (Ath) At2g32700 GI:18403052
Arabidopsis thaliana (Ath) At3g15880 GI:15233223
Arabidopsis thaliana (Ath) At3g16830 GI:15228877
Arabidopsis thaliana (Ath) At3g49660 GI:15229187
Arabidopsis thaliana (Ath) At4g02730 GI:15235470
Arabidopsis thaliana (Ath) At4g03020 GI:15236235
Arabidopsis thaliana (Ath) At4g32551 GI:7486768
Arabidopsis thaliana (Ath) At5g27030 GI:15240430
Arabidopsis thaliana (Ath) At5g43930 GI:15240053
Caenorhabditis elegans (Cel) CE00901
(WBGene00006474)
GI:17552164 Q17963
Caenorhabditis elegans (Cel) CE06574
(WBGene00013862)
GI:17566626
Caenorhabditis elegans (Cel) CE09086
(WBGene00008419)
GI:17506395 P90794
Caenorhabditis elegans (Cel) CE11748
(WBGene00010572)
GI:17568701 Q93847
Caenorhabditis elegans (Cel) CE23620 GI:17506397 P90794
Caenorhabditis elegans (Cel) CE28982
(WBGene00021467)
GI:17509921 Q95XR3
Drosophila melanogaster (Dme) 7290331
(FBgn0040066)
GI:17864654
Drosophila melanogaster (Dme) 7295309 GI:7295309 Q9VS00
Drosophila melanogaster (Dme) 7301300 GI:7301300
Drosophila melanogaster (Dme) 7302357 GI:7302357
Drosophila melanogaster (Dme) 7302720 GI:7302720
Homo sapiens (Hsa) Hs13129028 GI:13129028
Homo sapiens (Hsa) Hs13376751
(PAAF1)
GI:13376751 Q9BRP4
Homo sapiens (Hsa) Hs16445426
(WDR13)
GI:16445426 Q14827
Homo sapiens (Hsa) Hs16554627 GI:16554627 Q9H7J6
Homo sapiens (Hsa) Hs18565451 GI:18565451
Homo sapiens (Hsa) Hs18599360 GI:18599360
Homo sapiens (Hsa) Hs18677720
(WSB1)
GI:18677720 Q9Y656
Homo sapiens (Hsa) Hs20127645 GI:20127645
Homo sapiens (Hsa) Hs20143910 GI:20143910
Homo sapiens (Hsa) Hs20143912 GI:20143912 Q9Y656
Homo sapiens (Hsa) Hs21361641 GI:12053107 Q9NXT1
Homo sapiens (Hsa) Hs21450820 GI:19263503 Q8N1V2
Homo sapiens (Hsa) Hs21686975 GI:15278250
Homo sapiens (Hsa) Hs22046076 GI:22046076
Homo sapiens (Hsa) Hs22048015 GI:18676859 Q9H5C9
Homo sapiens (Hsa) Hs22052079 GI:22052079
Homo sapiens (Hsa) Hs8923273_1 GI:8923273
Homo sapiens (Hsa) Hs8923881
(WSB2)
GI:8923881 Q9NYS7
Homo sapiens (Hsa) Hs9506645 GI:9506645
Homo sapiens (Hsa) HsM8923075 GI:8923075
Saccharomyces cerevisiae (Sce) YBR175w
(S000000379)
GI:6319651 P38123
Saccharomyces cerevisiae (Sce) YCR084c
(S000000680)
GI:6319926 P16649
Saccharomyces cerevisiae (Sce) YGL004c
(S000002972)
GI:6321434 P53196
Schizosaccharomyces pombe (Spo) SPAC18B11.10 GI:19113785 Q09715
Schizosaccharomyces pombe (Spo) SPAC630.14c GI:19113822 Q9UUG8
Schizosaccharomyces pombe (Spo) SPBC354.03 GI:19112019 O43017


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000000680
GO:0000790 nuclear chromatin C
IC
SpoSPAC18B11.10
SPAC630.14c
SPBC354.03
GO:0005575 cellular_component C
ND
AthAt2g32700
GO:0005622 intracellular C
IDA
HsaWSB1
GO:0005634 nucleus C
IDA
AthAt4g32551
At1g15750
CelWBGene00008419
HsaWDR13
SceS000000680
S000002972
SpoSPAC18B11.10
SPAC630.14c
SPBC354.03
IPI
SceS000000680
GO:0005737 cytoplasm C
IDA
HsaWDR13
SceS000002972
SpoSPAC630.14c
GO:0005829 cytosol C
IDA
AthAt1g80490
At1g15750
SceS000002972
SpoSPAC18B11.10
SPAC630.14c
SPBC354.03
GO:0005834 heterotrimeric G-protein complex C
ISS
AthAt3g49660
At4g02730
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0040066
GO:0017053 transcriptional repressor complex C
IDA
SceS000000680
GO:0043234 protein complex C
NAS
SpoSPAC18B11.10
SPAC630.14c
GO:0044454 nuclear chromosome part C
RCA
SceS000000680
GO:0048188 Set1C/COMPASS complex C
IDA
SpoSPBC354.03
IPI
SceS000000379
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt4g03020
At2g25420
At4g02730
GO:0000166 nucleotide binding F
ISS
AthAt3g49660
At4g02730
At1g04140
At4g03020
At5g43930
GO:0003674 molecular_function F
ND
AthAt2g25420
At2g32700
SceS000002972
SpoSPBC354.03
GO:0003714 transcription corepressor activity F
IDA
SpoSPAC630.14c
IGI
SpoSPAC18B11.10
SPAC630.14c
TAS
SpoSPAC18B11.10
GO:0005515 protein binding F
IPI
AthAt3g16830
At3g15880
At5g27030
At1g15750
CelWBGene00008419
HsaPAAF1
WSB1
SpoSPAC18B11.10
SPAC630.14c
GO:0008134 transcription factor binding F
IPI
CelWBGene00008419
GO:0016564 transcription repressor activity F
IDA
AthAt1g15750
ISS
AthAt4g32551
GO:0016565 general transcriptional repressor
activity
F
IDA
SceS000000680
IMP
SceS000000680
IPI
SceS000000680
GO:0030234 enzyme regulator activity F
RCA
SceS000000680
GO:0042393 histone binding F
IDA
SpoSPAC630.14c
SPAC18B11.10
GO:0042800 histone methyltransferase activity (H3-K4
specific)
F
IDA
SceS000000379
IMP
SceS000000379
GO:0042803 protein homodimerization activity F
IPI
AthAt1g15750
GO:0046982 protein heterodimerization activity F
IPI
AthAt4g32551
GO:0060589 nucleoside-triphosphatase regulator
activity
F
RCA
SceS000000680
GO:0000003 reproduction P
IMP
CelWBGene00006474
WBGene00013862
GO:0000723 telomere maintenance P
IMP
SceS000000379
GO:0006338 chromatin remodeling P
IC
SpoSPBC354.03
GO:0006342 chromatin silencing P
IMP
SpoSPAC630.14c
TAS
SpoSPAC18B11.10
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000379
GO:0006479 protein amino acid methylation P
IMP
CelWBGene00006474
GO:0006508 proteolysis P
RCA
SceS000002972
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IMP
SceS000002972
GO:0006730 one-carbon metabolic process P
RCA
SceS000000379
GO:0007186 G-protein coupled receptor protein signaling
pathway
P
ISS
AthAt3g49660
GO:0008150 biological_process P
ND
AthAt4g02730
At1g04140
At4g03020
At2g25420
At5g43930
HsaWSB1
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00008419
GO:0009733 response to auxin stimulus P
IPI
AthAt1g15750
GO:0009790 embryo development P
IGI
AthAt2g32700
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00008419
GO:0009867 jasmonic acid mediated signaling
pathway
P
IMP
AthAt1g15750
GO:0009908 flower development P
IGI
AthAt2g32700
IMP
AthAt4g32551
GO:0010051 xylem and phloem pattern formation P
IGI
AthAt1g15750
GO:0010072 primary shoot apical meristem specification P
IGI
AthAt3g16830
At1g80490
At1g15750
At5g27030
At3g15880
IMP
AthAt1g15750
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter
P
IEP
SpoSPAC18B11.10
IMP
CelWBGene00008419
GO:0016246 RNA interference P
IMP
CelWBGene00006474
GO:0016481 negative regulation of transcription P
IDA
SceS000000680
IGI
AthAt4g32551
IMP
SceS000000680
IPI
AthAt2g32700
SceS000000680
RCA
SceS000000680
GO:0016584 nucleosome positioning P
IDA
SceS000000680
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000379
GO:0018991 oviposition P
IMP
CelWBGene00008419
GO:0033554 cellular response to stress P
IEP
SpoSPAC18B11.10
GO:0040007 growth