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Search term: YBR179C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FZO1
SGD link S000000383
Alternative ID YBR179C
Description Mitofusin, mitochondrial integral membrane protein involved in mitochondrial fusion and mitochondrial genome maintenance; contains N-terminal GTPase domain; targeted for destruction by cytosolic components of the ubiquitin-proteasome system
Synonyms YBR179C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0448 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Mitofusin 1 GTPase, involved in mitochondrila biogenesis

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03160 GI:15218732
Caenorhabditis elegans (Cel) CE02898
(WBGene00001509)		 GI:17538097 Q23424
Drosophila melanogaster (Dme) 7290714
(FBgn0029870)		 GI:20128953
Homo sapiens (Hsa) Hs16117785 GI:16117785
Homo sapiens (Hsa) Hs17486325 GI:17486325
Homo sapiens (Hsa) Hs7662004 GI:7662004 O95140
Homo sapiens (Hsa) Hs8923621 GI:8923621
Saccharomyces cerevisiae (Sce) YBR179c
(S000000383)		 GI:6319656 P38297
Schizosaccharomyces pombe (Spo) SPBC1706.03 GI:19112033 Q9USY7
Arabidopsis thaliana (Ath) At1g03160 GI:15218732
Caenorhabditis elegans (Cel) CE02898
(WBGene00001509)		 GI:17538097 Q23424
Drosophila melanogaster (Dme) 7290714
(FBgn0029870)		 GI:20128953
Homo sapiens (Hsa) Hs16117785 GI:16117785
Homo sapiens (Hsa) Hs17486325 GI:17486325
Homo sapiens (Hsa) Hs7662004 GI:7662004 O95140
Homo sapiens (Hsa) Hs8923621 GI:8923621
Saccharomyces cerevisiae (Sce) YBR179c
(S000000383)		 GI:6319656 P38297
Schizosaccharomyces pombe (Spo) SPBC1706.03 GI:19112033 Q9USY7
Arabidopsis thaliana (Ath) At1g03160 GI:15218732
Caenorhabditis elegans (Cel) CE02898
(WBGene00001509)		 GI:17538097 Q23424
Drosophila melanogaster (Dme) 7290714
(FBgn0029870)		 GI:20128953
Homo sapiens (Hsa) Hs16117785 GI:16117785
Homo sapiens (Hsa) Hs17486325 GI:17486325
Homo sapiens (Hsa) Hs7662004 GI:7662004 O95140
Homo sapiens (Hsa) Hs8923621 GI:8923621
Saccharomyces cerevisiae (Sce) YBR179c
(S000000383)		 GI:6319656 P38297
Schizosaccharomyces pombe (Spo) SPBC1706.03 GI:19112033 Q9USY7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000383
GO:0005740 mitochondrial envelope C
ISS
DmeFBgn0029870
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000383
S000000383
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000383
GO:0005886 plasma membrane C
NAS
DmeFBgn0029870
GO:0009507 chloroplast C
IDA
AthAt1g03160
GO:0031969 chloroplast membrane C
IDA
AthAt1g03160
GO:0003924 GTPase activity F
ISS
DmeFBgn0029870
SpoSPBC1706.03
TAS
SceS000000383
GO:0005525 GTP binding F
NAS
DmeFBgn0029870
GO:0006184 GTP catabolic process P
ISS
SpoSPBC1706.03
GO:0007005 mitochondrion organization P
ISS
SpoSPBC1706.03
NAS
DmeFBgn0029870
TAS
SceS000000383
GO:0008053 mitochondrial fusion P
IMP
CelWBGene00001509
SceS000000383
IPI
SceS000000383
ISS
DmeFBgn0029870
SpoSPBC1706.03
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001509
GO:0010027 thylakoid membrane organization P
IMP
AthAt1g03160
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IMP
AthAt1g03160
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001509
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001509

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31469

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) fzo1
(SPBC1706.03)		 GI:19112033 Q9USY7
Saccharomyces cerevisiae (Sce) FZO1
(S000000383)		 GI:6319656 P38297
Kluyveromyces lactis (Kla) KLLA0E24222g GI:50310055
Eremothecium gossypii (Ego) AGOS_ABR195C GI:45185427
Magnaporthe grisea (Mgr) MGG_05209 GI:39940062
Neurospora crassa (Ncr) NCU00436.1 GI:32403818


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000383
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000383
S000000383
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000383
GO:0003924 GTPase activity F
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0006184 GTP catabolic process P
ISS
SpoSPBC1706.03
GO:0007005 mitochondrion organization P
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0008053 mitochondrial fusion P
IMP
SceS000000383
IPI
SceS000000383
ISS
SpoSPBC1706.03

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11568

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago789 ABR195C
Candida glabrata (Cgl) cgl4929 CAGL0M06259g
Cryptococcus neoformans (Cne) cne1458 180.m00412
Debaryomyces hansenii (Dha) dha6498 DEHA0G17820g
Debaryomyces hansenii (Dha) dha6499 DEHA0G17831g
Kluyveromyces lactis (Kla) kla4040 KLLA0E24222g
Neurospora crassa (Ncr) ncr422 NCU00436.2
Saccharomyces cerevisiae (Sce) sce446 YBR179C
(S000000383)
Schizosaccharomyces pombe (Spo) spo1311 SPBC1706.03 Q9USY7
Yarrowia lipolytica (Yli) yli5718 YALI0F08899g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000383
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000383
S000000383
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000383
GO:0003924 GTPase activity F
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0006184 GTP catabolic process P
ISS
SpoSPBC1706.03
GO:0007005 mitochondrion organization P
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0008053 mitochondrial fusion P
IMP
SceS000000383
IPI
SceS000000383
ISS
SpoSPBC1706.03

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1706.03
(Q9USY7)		 YBR179C
(S000000383)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000383
GO:0005741 mitochondrial outer membrane C
IDA
SceS000000383
S000000383
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000383
GO:0003924 GTPase activity F
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0006184 GTP catabolic process P
ISS
SpoSPBC1706.03
GO:0007005 mitochondrion organization P
ISS
SpoSPBC1706.03
TAS
SceS000000383
GO:0008053 mitochondrial fusion P
IMP
SceS000000383
IPI
SceS000000383
ISS
SpoSPBC1706.03

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