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Search term: YBR193C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MED8
SGD link S000000397
Alternative ID YBR193C
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
Synonyms YBR193C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38446

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MED8
(S000000397)		 GI:6319670
Kluyveromyces lactis (Kla) KLLA0E23683g GI:50310007
Eremothecium gossypii (Ego) AGOS_AEL252C GI:45190355


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016592 mediator complex C
IDA
SceS000000397
GO:0016455 RNA polymerase II transcription mediator
activity		 F
IDA
SceS000000397
GO:0006366 transcription from RNA polymerase II
promoter		 P
IDA
SceS000000397
RCA
SceS000000397

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15252

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2254 AEL252C
Candida glabrata (Cgl) cgl4884 CAGL0M05247g
Debaryomyces hansenii (Dha) dha4795 DEHA0F09295g
Kluyveromyces lactis (Kla) kla4016 KLLA0E23683g
Neurospora crassa (Ncr) ncr8152 NCU08365.2
Saccharomyces cerevisiae (Sce) sce462 YBR193C
(S000000397)
Schizosaccharomyces pombe (Spo) spo4516 SPBC21.04 O94646
Yarrowia lipolytica (Yli) yli830 YALI0B02068g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC21.04
GO:0005829 cytosol C
IDA
SpoSPBC21.04
GO:0016592 mediator complex C
IDA
SceS000000397
SpoSPBC21.04
NAS
SpoSPBC21.04
GO:0005515 protein binding F
IPI
SpoSPBC21.04
GO:0016455 RNA polymerase II transcription mediator
activity		 F
IDA
SceS000000397
GO:0000920 cytokinetic cell separation P
IMP
SpoSPBC21.04
GO:0006366 transcription from RNA polymerase II
promoter		 P
IC
SpoSPBC21.04
IDA
SceS000000397
RCA
SceS000000397
GO:0034613 cellular protein localization P
IGI
SpoSPBC21.04

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC21.04
(O94646)		 YBR193C
(S000000397)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC21.04
GO:0005829 cytosol C
IDA
SpoSPBC21.04
GO:0016592 mediator complex C
IDA
SceS000000397
SpoSPBC21.04
NAS
SpoSPBC21.04
GO:0005515 protein binding F
IPI
SpoSPBC21.04
GO:0016455 RNA polymerase II transcription mediator
activity		 F
IDA
SceS000000397
GO:0000920 cytokinetic cell separation P
IMP
SpoSPBC21.04
GO:0006366 transcription from RNA polymerase II
promoter		 P
IC
SpoSPBC21.04
IDA
SceS000000397
RCA
SceS000000397
GO:0034613 cellular protein localization P
IGI
SpoSPBC21.04

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