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Search term: YBR195C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSI1
SGD link S000000399
Alternative ID YBR195C
Description Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46
Synonyms YBR195C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0264 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g16780 GI:15227294
Arabidopsis thaliana (Ath) At2g19520 GI:16323103
Arabidopsis thaliana (Ath) At4g29730 GI:15233674
Arabidopsis thaliana (Ath) At4g35050 GI:15236251
Arabidopsis thaliana (Ath) At5g58230 GI:15237140
Caenorhabditis elegans (Cel) CE11860
(WBGene00004312)		 GI:17508661 P90917
Caenorhabditis elegans (Cel) CE16234
(WBGene00003036)		 GI:17508127 P90916
Drosophila melanogaster (Dme) 7299974
(FBgn0015610)		 GI:17933648
Homo sapiens (Hsa) Hs13631383 GI:13631383
Homo sapiens (Hsa) Hs14249586 GI:14249586
Homo sapiens (Hsa) Hs17463450 GI:17463450
Homo sapiens (Hsa) Hs20533300 GI:20533300
Homo sapiens (Hsa) Hs20551282 GI:20551282
Homo sapiens (Hsa) Hs22048320 GI:22048320
Homo sapiens (Hsa) Hs4506439
(RBBP7)		 GI:4506439 Q16576
Homo sapiens (Hsa) Hs5032027
(RBBP4)		 GI:5032027 Q09028
Saccharomyces cerevisiae (Sce) YBR195c
(S000000399)		 GI:6319672 P13712
Saccharomyces cerevisiae (Sce) YEL056w
(S000000782)		 GI:6320779 P39984
Schizosaccharomyces pombe (Spo) SPAC25H1.06 GI:19114722 Q9Y825
Schizosaccharomyces pombe (Spo) SPAC29A4.18 GI:19115776 O14021
Schizosaccharomyces pombe (Spo) SPCC1672.10 GI:19075381 O94244
Encephalitozoon cuniculi (Ecu) ECU07g0750 GI:19074497 Q8SRK1
Arabidopsis thaliana (Ath) At2g16780 GI:15227294
Arabidopsis thaliana (Ath) At2g19520 GI:16323103
Arabidopsis thaliana (Ath) At4g29730 GI:15233674
Arabidopsis thaliana (Ath) At4g35050 GI:15236251
Arabidopsis thaliana (Ath) At5g58230 GI:15237140
Caenorhabditis elegans (Cel) CE11860
(WBGene00004312)		 GI:17508661 P90917
Caenorhabditis elegans (Cel) CE16234
(WBGene00003036)		 GI:17508127 P90916
Drosophila melanogaster (Dme) 7299974
(FBgn0015610)		 GI:17933648
Homo sapiens (Hsa) Hs13631383 GI:13631383
Homo sapiens (Hsa) Hs14249586 GI:14249586
Homo sapiens (Hsa) Hs17463450 GI:17463450
Homo sapiens (Hsa) Hs20533300 GI:20533300
Homo sapiens (Hsa) Hs20551282 GI:20551282
Homo sapiens (Hsa) Hs22048320 GI:22048320
Homo sapiens (Hsa) Hs4506439
(RBBP7)		 GI:4506439 Q16576
Homo sapiens (Hsa) Hs5032027
(RBBP4)		 GI:5032027 Q09028
Saccharomyces cerevisiae (Sce) YBR195c
(S000000399)		 GI:6319672 P13712
Saccharomyces cerevisiae (Sce) YEL056w
(S000000782)		 GI:6320779 P39984
Schizosaccharomyces pombe (Spo) SPAC25H1.06 GI:19114722 Q9Y825
Schizosaccharomyces pombe (Spo) SPAC29A4.18 GI:19115776 O14021
Schizosaccharomyces pombe (Spo) SPCC1672.10 GI:19075381 O94244
Encephalitozoon cuniculi (Ecu) ECU07g0750 GI:19074497 Q8SRK1
Arabidopsis thaliana (Ath) At2g16780 GI:15227294
Arabidopsis thaliana (Ath) At2g19520 GI:16323103
Arabidopsis thaliana (Ath) At4g29730 GI:15233674
Arabidopsis thaliana (Ath) At4g35050 GI:15236251
Arabidopsis thaliana (Ath) At5g58230 GI:15237140
Caenorhabditis elegans (Cel) CE11860
(WBGene00004312)		 GI:17508661 P90917
Caenorhabditis elegans (Cel) CE16234
(WBGene00003036)		 GI:17508127 P90916
Drosophila melanogaster (Dme) 7299974
(FBgn0015610)		 GI:17933648
Homo sapiens (Hsa) Hs13631383 GI:13631383
Homo sapiens (Hsa) Hs14249586 GI:14249586
Homo sapiens (Hsa) Hs17463450 GI:17463450
Homo sapiens (Hsa) Hs20533300 GI:20533300
Homo sapiens (Hsa) Hs20551282 GI:20551282
Homo sapiens (Hsa) Hs22048320 GI:22048320
Homo sapiens (Hsa) Hs4506439
(RBBP7)		 GI:4506439 Q16576
Homo sapiens (Hsa) Hs5032027
(RBBP4)		 GI:5032027 Q09028
Saccharomyces cerevisiae (Sce) YBR195c
(S000000399)		 GI:6319672 P13712
Saccharomyces cerevisiae (Sce) YEL056w
(S000000782)		 GI:6320779 P39984
Schizosaccharomyces pombe (Spo) SPAC25H1.06 GI:19114722 Q9Y825
Schizosaccharomyces pombe (Spo) SPAC29A4.18 GI:19115776 O14021
Schizosaccharomyces pombe (Spo) SPCC1672.10 GI:19075381 O94244
Encephalitozoon cuniculi (Ecu) ECU07g0750 GI:19074497 Q8SRK1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000123 histone acetyltransferase complex C
IDA
SceS000000782
IPI
SceS000000782
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SpoSPCC1672.10
GO:0000790 nuclear chromatin C
IC
SpoSPAC25H1.06
IDA
SpoSPCC1672.10
NAS
SpoSPAC25H1.06
GO:0005634 nucleus C
IDA
AthAt2g19520
CelWBGene00003036
DmeFBgn0015610
HsaRBBP4
SceS000000782
SpoSPAC25H1.06
SPAC29A4.18
SPCC1672.10
NAS
DmeFBgn0015610
TAS
AthAt5g58230
GO:0005667 transcription factor complex C
IPI
DmeFBgn0015610
GO:0005677 chromatin silencing complex C
IMP
SceS000000399
GO:0005678 chromatin assembly complex C
NAS
DmeFBgn0015610
GO:0005700 polytene chromosome C
IDA
DmeFBgn0015610
GO:0005730 nucleolus C
IDA
AthAt2g19520
GO:0005737 cytoplasm C
IDA
AthAt2g19520
SceS000000782
SpoSPAC25H1.06
GO:0005829 cytosol C
IDA
SpoSPAC25H1.06
SPAC29A4.18
SPCC1672.10
GO:0009507 chloroplast C
IDA
AthAt5g58230
GO:0016580 Sin3 complex C
NAS
HsaRBBP4
GO:0016581 NuRD complex C
IDA
HsaRBBP7
RBBP4
NAS
HsaRBBP4
GO:0016585 chromatin remodeling complex C
IPI
AthAt5g58230
NAS
DmeFBgn0015610
GO:0016589 NURF complex C
IPI
DmeFBgn0015610
NAS
DmeFBgn0015610
TAS
DmeFBgn0015610
GO:0031511 Mis6-Sim4 complex C
TAS
SpoSPCC1672.10
GO:0031523 Myb complex C
IDA
DmeFBgn0015610
GO:0032221 Rpd3S complex C
IDA
SpoSPAC29A4.18
GO:0033186 CAF-1 complex C
IDA
SceS000000399
SpoSPAC25H1.06
GO:0033698 Rpd3L complex C
IDA
SpoSPAC29A4.18
GO:0035098 ESC/E(Z) complex C
IDA
DmeFBgn0015610
HsaRBBP4
RBBP7
GO:0043596 nuclear replication fork C
IDA
SpoSPAC25H1.06
GO:0070210 Rpd3L-Expanded complex C
IDA
SpoSPAC29A4.18
GO:0080008 CUL4 RING ubiquitin ligase complex C
IPI
AthAt4g35050
ISS
AthAt2g19520
At4g29730
At5g58230
At2g16780
GO:0003674 molecular_function F
ND
AthAt4g29730
At2g16780
SpoSPAC25H1.06
GO:0003682 chromatin binding F
NAS
DmeFBgn0015610
GO:0004402 histone acetyltransferase activity F
IDA
SceS000000782
IMP
SceS000000782
IPI
SceS000000782
GO:0005515 protein binding F
IPI
AthAt4g35050
At5g58230
CelWBGene00004312
WBGene00003036
HsaRBBP4
RBBP7
SpoSPAC29A4.18
SPCC1672.10
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaRBBP4
GO:0030528 transcription regulator activity F
IMP
SceS000000399
GO:0035035 histone acetyltransferase binding F
IPI
DmeFBgn0015610
ISS
DmeFBgn0015610
GO:0042054 histone methyltransferase activity F
IDA
DmeFBgn0015610
GO:0042393 histone binding F
IDA
SceS000000782
NAS
DmeFBgn0015610
HsaRBBP4
TAS
DmeFBgn0015610
GO:0042826 histone deacetylase binding F
IPI
DmeFBgn0015610
HsaRBBP4
ISS
DmeFBgn0015610
GO:0046872 metal ion binding F
IDA
AthAt2g19520
GO:0046974 histone methyltransferase activity (H3-K9
specific)		 F
IC
DmeFBgn0015610
GO:0046976 histone methyltransferase activity (H3-K27
specific)		 F
IC
DmeFBgn0015610
GO:0000003 reproduction P
IMP
CelWBGene00004312
WBGene00003036
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPAC29A4.18
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IMP
DmeFBgn0015610
GO:0000910 cytokinesis P
IMP
DmeFBgn0015610
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00004312
GO:0001708 cell fate specification P
IMP
CelWBGene00004312
WBGene00003036
GO:0002119 nematode larval development P
IMP
CelWBGene00003036
GO:0006281 DNA repair P
IMP
SceS000000399
TAS
DmeFBgn0015610
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000000782
GO:0006334 nucleosome assembly P
IDA
DmeFBgn0015610
NAS
DmeFBgn0015610
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IC
SpoSPAC25H1.06
IMP
SceS000000399
NAS
DmeFBgn0015610
GO:0006338 chromatin remodeling P
IC
SpoSPAC29A4.18
IDA
HsaRBBP4
GO:0006342 chromatin silencing P
IMP
SceS000000399
IPI
DmeFBgn0015610
ISS
SpoSPAC29A4.18
GO:0006348 chromatin silencing at telomere P
IGI
SceS000000782
GO:0006349 regulation of gene expression by genetic
imprinting		 P
IPI
AthAt5g58230
GO:0006350 transcription P
IDA
DmeFBgn0015610
GO:0007059 chromosome segregation P
IMP
SpoSPCC1672.10
GO:0007265 Ras protein signal transduction P
TAS
SceS000000399
GO:0007275 multicellular organismal development P
IMP
AthAt5g58230
TAS
HsaRBBP7
GO:0007307 eggshell chorion gene amplification P
IC
DmeFBgn0015610
GO:0007346 regulation of mitotic cell cycle P
IMP
DmeFBgn0015610
GO:0007369 gastrulation P
IMP
CelWBGene00004312
GO:0007517 muscle organ development P
IMP
DmeFBgn0015610
GO:0008150 biological_process P
ND
AthAt4g29730
At2g16780
At4g35050
GO:0008283 cell proliferation P
IMP
AthAt5g58230
TAS
HsaRBBP7
GO:0008285 negative regulation of cell proliferation P
TAS
HsaRBBP4
GO:0009555 pollen development P
IGI
AthAt5g58230
IMP
AthAt5g58230
GO:0009790 embryo development P
IMP
CelWBGene00004312
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004312
WBGene00003036
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g58230
GO:0009826 unidimensional cell growth P
IMP
AthAt2g19520
GO:0009908 flower development P
IMP
AthAt2g19520
GO:0009909 regulation of flower development P
IMP
AthAt5g58230
GO:0009965 leaf morphogenesis P
IMP
AthAt2g19520
GO:0010026 trichome differentiation P
IMP
AthAt5g58230
GO:0010090 trichome morphogenesis P
IMP
AthAt2g19520
GO:0010214 seed coat development P
IMP
AthAt5g58230
GO:0016246 RNA interference P
IMP
CelWBGene00004312
GO:0016568 chromatin modification P
IMP
AthAt5g58230
GO:0016571 histone methylation P
IDA
DmeFBgn0015610
GO:0016573 histone acetylation P
IDA
DmeFBgn0015610
SceS000000782
IMP
SceS000000782
ISS
DmeFBgn0015610
GO:0016575 histone deacetylation P
IMP
SpoSPAC29A4.18
SPCC1672.10
GO:0016584 nucleosome positioning P
IDA
DmeFBgn0015610
GO:0030261 chromosome condensation P
IMP
SpoSPAC29A4.18
GO:0030308 negative regulation of cell growth P
IDA
HsaRBBP7
GO:0031055 chromatin remodeling at centromere P
IMP
SpoSPCC1672.10
GO:0031066 regulation of histone deacetylation at
centromere		 P
IMP
SpoSPCC1672.10
GO:0031507 heterochromatin formation P
IMP
AthAt5g58230
GO:0034080 CenH3-containing nucleosome assembly at
centromere		 P
TAS
SpoSPCC1672.10
GO:0034613 cellular protein localization P
IGI
SpoSPCC1672.10
GO:0035067 negative regulation of histone
acetylation		 P
IMP
SpoSPAC25H1.06
GO:0040011 locomotion P
IMP
CelWBGene00004312
GO:0040027 negative regulation of vulval development P
IMP
CelWBGene00003036
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004312
WBGene00003036
GO:0042766 nucleosome mobilization P
IDA
DmeFBgn0015610
GO:0045138 tail tip morphogenesis P
IMP
CelWBGene00004312
WBGene00003036
GO:0045787 positive regulation of cell cycle P
IGI
AthAt5g58230
GO:0048316 seed development P
IMP
AthAt5g58230
GO:0048366 leaf development P
IMP
AthAt5g58230
GO:0048557 embryonic digestive tract morphogenesis P
IGI
CelWBGene00003036
GO:0048666 neuron development P
IMP
DmeFBgn0015610
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0015610
GO:0051382 kinetochore assembly P
TAS
SpoSPCC1672.10
GO:0051574 positive regulation of histone H3-K9
methylation		 P
IMP
SpoSPAC25H1.06
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPCC1672.10
GO:0070370 cellular heat acclimation P
IDA
HsaRBBP7
GO:0070829 heterochromatin maintenance P
IMP
SpoSPAC25H1.06
GO:0090053 positive regulation of chromatin silencing at
centromere		 P
IMP
SpoSPAC25H1.06
GO:0090055 positive regulation of chromatin silencing at
silent mating-type cassette		 P
IMP
SpoSPAC25H1.06

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56057

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MSI1
(S000000399)		 GI:6319672 P13712
Kluyveromyces lactis (Kla) KLLA0E23617g GI:50310001
Eremothecium gossypii (Ego) AGOS_AEL250C GI:45190357


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005677 chromatin silencing complex C
IMP
SceS000000399
GO:0033186 CAF-1 complex C
IDA
SceS000000399
GO:0030528 transcription regulator activity F
IMP
SceS000000399
GO:0006281 DNA repair P
IMP
SceS000000399
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IMP
SceS000000399
GO:0006342 chromatin silencing P
IMP
SceS000000399
GO:0007265 Ras protein signal transduction P
TAS
SceS000000399

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20754

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2256 AEL250C
Candida glabrata (Cgl) cgl4886 CAGL0M05291g
Debaryomyces hansenii (Dha) dha4773 DEHA0F08811g
Kluyveromyces lactis (Kla) kla4013 KLLA0E23617g
Saccharomyces cerevisiae (Sce) sce464 YBR195C
(S000000399)
Yarrowia lipolytica (Yli) yli1305 YALI0B13750g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005677 chromatin silencing complex C
IMP
SceS000000399
GO:0033186 CAF-1 complex C
IDA
SceS000000399
GO:0030528 transcription regulator activity F
IMP
SceS000000399
GO:0006281 DNA repair P
IMP
SceS000000399
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IMP
SceS000000399
GO:0006342 chromatin silencing P
IMP
SceS000000399
GO:0007265 Ras protein signal transduction P
TAS
SceS000000399

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC25H1.06
(Q9Y825)		 YBR195C
(S000000399)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC25H1.06
NAS
SpoSPAC25H1.06
GO:0005634 nucleus C
IDA
SpoSPAC25H1.06
GO:0005677 chromatin silencing complex C
IMP
SceS000000399
GO:0005737 cytoplasm C
IDA
SpoSPAC25H1.06
GO:0005829 cytosol C
IDA
SpoSPAC25H1.06
GO:0033186 CAF-1 complex C
IDA
SceS000000399
SpoSPAC25H1.06
GO:0043596 nuclear replication fork C
IDA
SpoSPAC25H1.06
GO:0003674 molecular_function F
ND
SpoSPAC25H1.06
GO:0030528 transcription regulator activity F
IMP
SceS000000399
GO:0006281 DNA repair P
IMP
SceS000000399
GO:0006335 DNA replication-dependent nucleosome
assembly		 P
IC
SpoSPAC25H1.06
IMP
SceS000000399
GO:0006342 chromatin silencing P
IMP
SceS000000399
GO:0007265 Ras protein signal transduction P
TAS
SceS000000399
GO:0035067 negative regulation of histone
acetylation		 P
IMP
SpoSPAC25H1.06
GO:0051574 positive regulation of histone H3-K9
methylation		 P
IMP
SpoSPAC25H1.06
GO:0070829 heterochromatin maintenance P
IMP
SpoSPAC25H1.06
GO:0090053 positive regulation of chromatin silencing at
centromere		 P
IMP
SpoSPAC25H1.06
GO:0090055 positive regulation of chromatin silencing at
silent mating-type cassette		 P
IMP
SpoSPAC25H1.06

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Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

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