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Search term: YBR221C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDB1
SGD link S000000425
Alternative ID YBR221C
Description E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria
Synonyms YBR221C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0524 ACDHYPE

KOGs classification KOGs description
METABOLISM Pyruvate dehydrogenase E1, beta subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g30120 GI:15220670
Arabidopsis thaliana (Ath) At2g34590 GI:15226781
Arabidopsis thaliana (Ath) At5g50850 GI:15241286
Caenorhabditis elegans (Cel) CE27647
(WBGene00015413)		 GI:17538422 O44451
Drosophila melanogaster (Dme) 7301743 GI:7301743
Homo sapiens (Hsa) Hs20469608 GI:20469608
Homo sapiens (Hsa) Hs4505687 GI:4505687
Saccharomyces cerevisiae (Sce) YBR221c
(S000000425)		 GI:6319698 P32473
Schizosaccharomyces pombe (Spo) SPBC30D10.13c GI:19113064 Q09171
Encephalitozoon cuniculi (Ecu) ECU04g1160 GI:19074194 Q8SS26
Arabidopsis thaliana (Ath) At1g30120 GI:15220670
Arabidopsis thaliana (Ath) At2g34590 GI:15226781
Arabidopsis thaliana (Ath) At5g50850 GI:15241286
Caenorhabditis elegans (Cel) CE27647
(WBGene00015413)		 GI:17538422 O44451
Drosophila melanogaster (Dme) 7301743 GI:7301743
Homo sapiens (Hsa) Hs20469608 GI:20469608
Homo sapiens (Hsa) Hs4505687 GI:4505687
Saccharomyces cerevisiae (Sce) YBR221c
(S000000425)		 GI:6319698 P32473
Schizosaccharomyces pombe (Spo) SPBC30D10.13c GI:19113064 Q09171
Encephalitozoon cuniculi (Ecu) ECU04g1160 GI:19074194 Q8SS26
Arabidopsis thaliana (Ath) At1g30120 GI:15220670
Arabidopsis thaliana (Ath) At2g34590 GI:15226781
Arabidopsis thaliana (Ath) At5g50850 GI:15241286
Caenorhabditis elegans (Cel) CE27647
(WBGene00015413)		 GI:17538422 O44451
Drosophila melanogaster (Dme) 7301743 GI:7301743
Homo sapiens (Hsa) Hs20469608 GI:20469608
Homo sapiens (Hsa) Hs4505687 GI:4505687
Saccharomyces cerevisiae (Sce) YBR221c
(S000000425)		 GI:6319698 P32473
Schizosaccharomyces pombe (Spo) SPBC30D10.13c GI:19113064 Q09171
Encephalitozoon cuniculi (Ecu) ECU04g1160 GI:19074194 Q8SS26


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
AthAt5g50850
GO:0005739 mitochondrion C
IDA
AthAt5g50850
SceS000000425
SpoSPBC30D10.13c
IMP
SceS000000425
GO:0005886 plasma membrane C
IDA
AthAt5g50850
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0009507 chloroplast C
IDA
AthAt2g34590
At1g30120
TAS
AthAt1g30120
GO:0009941 chloroplast envelope C
IDA
AthAt2g34590
At1g30120
GO:0010240 plastid pyruvate dehydrogenase
complex		 C
TAS
AthAt1g30120
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000425
GO:0004739 pyruvate dehydrogenase (acetyl-transferring)
activity		 F
IMP
SceS000000425
ISS
AthAt1g30120
At5g50850
SpoSPBC30D10.13c
NAS
AthAt2g34590
TAS
AthAt1g30120
GO:0004802 transketolase activity F
ISS
AthAt2g34590
GO:0008270 zinc ion binding F
IDA
AthAt2g34590
GO:0006082 organic acid metabolic process P
RCA
SceS000000425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0006633 fatty acid biosynthetic process P
TAS
AthAt1g30120
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015413
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00015413
GO:0042742 defense response to bacterium P
IEP
AthAt5g50850
GO:0048868 pollen tube development P
IMP
AthAt2g34590
GO:0055114 oxidation reduction P
RCA
SceS000000425

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
712

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PDHB GI:156564403
Pan troglodytes (Ptr) PDHB GI:114587603
Canis familiaris (Cfa) PDHB GI:73985153
Mus musculus (Mmu) Pdhb
(MGI:1915513)		 GI:18152793 Q9D051
Rattus norvegicus (Rno) Pdhb
(RGD:1359146)		 GI:56090293
Gallus gallus (Gga) PDHB GI:50754481
Drosophila melanogaster (Dme) CG11876
(FBgn0039635)		 GI:21358145
Anopheles gambiae (Aga) AgaP_AGAP010421 GI:58381888
Caenorhabditis elegans (Cel) C04C3.3
(CE27647;
WBGene00015413)		 GI:17538422 O44451
Schizosaccharomyces pombe (Spo) pdb1
(SPBC30D10.13c)		 GI:19113064 Q09171
Saccharomyces cerevisiae (Sce) PDB1
(S000000425)		 GI:6319698 P32473
Kluyveromyces lactis (Kla) KLLA0F09603g GI:50310987
Eremothecium gossypii (Ego) AGOS_AAR167C GI:45184992
Magnaporthe grisea (Mgr) MGG_10569 GI:39969921
Neurospora crassa (Ncr) NCU03004.1 GI:32419495
Arabidopsis thaliana (Ath) MAB1 GI:15241286
Oryza sativa (Osa) Os08g0536000 GI:115477529
Oryza sativa (Osa) Os09g0509200 GI:115480067


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthMAB1
GO:0005730 nucleolus C
IDA
AthMAB1
GO:0005739 mitochondrion C
IDA
AthMAB1
MmuMGI:1915513
SceS000000425
SpoSPBC30D10.13c
IMP
SceS000000425
ISO
MmuMGI:1915513
GO:0005811 lipid particle C
IDA
DmeFBgn0039635
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0039635
GO:0005886 plasma membrane C
IDA
AthMAB1
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000425
GO:0045254 pyruvate dehydrogenase complex C
ISO
MmuMGI:1915513
ISS
DmeFBgn0039635
GO:0003674 molecular_function F
ND
AthMAB1
GO:0004739 pyruvate dehydrogenase (acetyl-transferring)
activity		 F
IMP
SceS000000425
ISO
MmuMGI:1915513
ISS
AthMAB1
DmeFBgn0039635
SpoSPBC30D10.13c
GO:0019825 oxygen binding F
ISS
AthMAB1
GO:0006082 organic acid metabolic process P
RCA
SceS000000425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000000425
ISO
MmuMGI:1915513
ISS
SpoSPBC30D10.13c
GO:0006090 pyruvate metabolic process P
ISS
DmeFBgn0039635
GO:0006099 tricarboxylic acid cycle P
TAS
HsaPDHB
GO:0008150 biological_process P
ND
AthMAB1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015413
GO:0010510 regulation of acetyl-CoA biosynthetic process from
pyruvate		 P
EXP
HsaPDHB
GO:0031122 cytoplasmic microtubule organization P
IMP
DmeFBgn0039635
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00015413
GO:0042742 defense response to bacterium P
IEP
AthMAB1
GO:0055114 oxidation reduction P
RCA
SceS000000425

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1272

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7337 ENSANGP00000010075
Ashbya gossypii (Ago) ago355 AAR167C
Arabidopsis thaliana (Ath) ath3146 At1g30120.1
Arabidopsis thaliana (Ath) ath10509 At2g34590.1
Arabidopsis thaliana (Ath) ath27019 At5g50850.1
Caenorhabditis elegans (Cel) cel992 C04C3.3
(CE27647;
WBGene00015413)
Candida glabrata (Cgl) cgl3815 CAGL0K06831g
Dictyostelium discoideum (Ddi) ddi12117 DDB0229442
Debaryomyces hansenii (Dha) dha1875 DEHA0C10065g
Drosophila melanogaster (Dme) dme14950 CG11876-PA
(FBgn0039635)
Drosophila melanogaster (Dme) dme14952 CG11876-PD
(FBgn0039635)
Danio rerio (Dre) dre14143 ENSDARP00000002122
(pdhb)		 Q7T368
Encephalitozoon cuniculi (Ecu) ecu832 19074194
Takifugu rubripes (Fru) fru6840 SINFRUP00000157804
Gallus gallus (Gga) gga5369 ENSGALP00000011491
(PDHB)
Homo sapiens (Hsa) hsa22694 ENSP00000307241
(PDHB)		 P11177-1
Kluyveromyces lactis (Kla) kla4516 KLLA0F09603g
Mus musculus (Mmu) mmu7641 ENSMUSP00000022268
(MGI:1915513)		 Q9D051
Neurospora crassa (Ncr) ncr2909 NCU03004.2
Oryza sativa (Osa) osa52856 5945.m00159
Oryza sativa (Osa) osa52880 5945.m00198
Oryza sativa (Osa) osa59584 6525.m00290
Oryza sativa (Osa) osa61644 6596.m00290
Oryza sativa (Osa) osa73858 7130.m00207
Oryza sativa (Osa) osa75520 7234.m00136
Oryza sativa (Osa) osa76124 7253.m00133
Plasmodium falciparum (Pfa) pfa1121 PF14_0441
Rattus norvegicus (Rno) rno11094 ENSRNOP00000010545
(RGD:1359146)		 P49432
Saccharomyces cerevisiae (Sce) sce493 YBR221C
(S000000425)
Schizosaccharomyces pombe (Spo) spo3606 SPBC30D10.13c Q09171
Yarrowia lipolytica (Yli) yli4972 YALI0E27005g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
AthAt5g50850
GO:0005739 mitochondrion C
IDA
AthAt5g50850
MmuMGI:1915513
SceS000000425
SpoSPBC30D10.13c
IMP
SceS000000425
ISO
MmuMGI:1915513
GO:0005811 lipid particle C
IDA
DmeFBgn0039635
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0039635
GO:0005886 plasma membrane C
IDA
AthAt5g50850
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0009507 chloroplast C
IDA
AthAt2g34590
At1g30120
TAS
AthAt1g30120
GO:0009941 chloroplast envelope C
IDA
AthAt2g34590
At1g30120
GO:0010240 plastid pyruvate dehydrogenase
complex		 C
TAS
AthAt1g30120
GO:0020011 apicoplast C
IDA
PfaPF14_0441
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000425
GO:0045254 pyruvate dehydrogenase complex C
ISO
MmuMGI:1915513
ISS
DmeFBgn0039635
GO:0003674 molecular_function F
ND
PfaPF14_0441
GO:0004739 pyruvate dehydrogenase (acetyl-transferring)
activity		 F
IMP
SceS000000425
ISO
MmuMGI:1915513
ISS
AthAt1g30120
At5g50850
DmeFBgn0039635
SpoSPBC30D10.13c
NAS
AthAt2g34590
TAS
AthAt1g30120
GO:0004802 transketolase activity F
ISS
AthAt2g34590
GO:0008270 zinc ion binding F
IDA
AthAt2g34590
GO:0006082 organic acid metabolic process P
RCA
SceS000000425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000000425
ISO
MmuMGI:1915513
ISS
SpoSPBC30D10.13c
GO:0006090 pyruvate metabolic process P
ISS
DmeFBgn0039635
GO:0006633 fatty acid biosynthetic process P
TAS
AthAt1g30120
GO:0008150 biological_process P
ND
PfaPF14_0441
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00015413
GO:0031122 cytoplasmic microtubule organization P
IMP
DmeFBgn0039635
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00015413
GO:0042742 defense response to bacterium P
IEP
AthAt5g50850
GO:0048868 pollen tube development P
IMP
AthAt2g34590
GO:0055114 oxidation reduction P
RCA
SceS000000425

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30D10.13c
(Q09171)		 YBR221C
(S000000425)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000000425
SpoSPBC30D10.13c
IMP
SceS000000425
GO:0005967 mitochondrial pyruvate dehydrogenase
complex		 C
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000425
GO:0004739 pyruvate dehydrogenase (acetyl-transferring)
activity		 F
IMP
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0006082 organic acid metabolic process P
RCA
SceS000000425
GO:0006086 acetyl-CoA biosynthetic process from
pyruvate		 P
IDA
SceS000000425
ISS
SpoSPBC30D10.13c
GO:0055114 oxidation reduction P
RCA
SceS000000425

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GO info in one table:

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