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Search term: YBR228W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SLX1
SGD link S000000432
Alternative ID YBR228W
Description Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
Synonyms YBR228W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3005 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED GIY-YIG type nuclease

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g30350 GI:15227738
Arabidopsis thaliana (Ath) At5g43210 GI:15239808
Caenorhabditis elegans (Cel) CE11216
(WBGene00018909)		 GI:17507665 P91351
Drosophila melanogaster (Dme) 7296834 GI:7296834
Homo sapiens (Hsa) Hs13129004
(GIYD2)		 GI:13129004 Q9H5H2
Saccharomyces cerevisiae (Sce) YBR228w
(S000000432)		 GI:6319705 P38324
Schizosaccharomyces pombe (Spo) SPAP27G11.15 GI:19114332 Q9P7M3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
ISS
AthAt2g30350
At5g43210
GO:0005634 nucleus C
IC
SceS000000432
GO:0030874 nucleolar chromatin C
IDA
SpoSPAP27G11.15
GO:0033557 Slx1-Slx4 complex C
IDA
SpoSPAP27G11.15
IPI
SceS000000432
GO:0004518 nuclease activity F
ISS
AthAt5g43210
At2g30350
GO:0005515 protein binding F
IPI
SpoSPAP27G11.15
GO:0016894 endonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
3'-phosphomonoesters		 F
IDA
SpoSPAP27G11.15
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000000432
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPAP27G11.15
GO:0002119 nematode larval development P
IMP
CelWBGene00018909
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000000432
GO:0006281 DNA repair P
ISS
AthAt5g43210
At2g30350
GO:0006974 response to DNA damage stimulus P
IGI
SceS000000432
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00018909
GO:0031297 replication fork processing P
NAS
SpoSPAP27G11.15
GO:0034065 replication fork processing at rDNA
locus		 P
TAS
SpoSPAP27G11.15
GO:0040007 growth P
IMP
CelWBGene00018909
GO:0043007 maintenance of rDNA P
IMP
SpoSPAP27G11.15
GO:0045458 recombination within rDNA repeats P
IDA
SpoSPAP27G11.15

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104069

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SLX1
(S000000432)		 GI:6319705 P38324
Kluyveromyces lactis (Kla) KLLA0F09713g GI:50310997
Eremothecium gossypii (Ego) AGOS_AAR172W GI:45184997
Magnaporthe grisea (Mgr) MGG_04879 GI:145602474
Neurospora crassa (Ncr) NCU01236.1 GI:32412498


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000432
GO:0033557 Slx1-Slx4 complex C
IPI
SceS000000432
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000000432
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000000432
GO:0006974 response to DNA damage stimulus P
IGI
SceS000000432

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2268

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4406 ENSANGP00000021811
Anopheles gambiae (Aga) aga4405 ENSANGP00000026512
Ashbya gossypii (Ago) ago360 AAR172W
Arabidopsis thaliana (Ath) ath10013 At2g30350.1
Arabidopsis thaliana (Ath) ath10014 At2g30350.2
Caenorhabditis elegans (Cel) cel10496 F56A3.2
(CE11216;
WBGene00018909)
Candida glabrata (Cgl) cgl3820 CAGL0K06941g
Cryptococcus neoformans (Cne) cne2573 181.m08764
Debaryomyces hansenii (Dha) dha1038 DEHA0B08041g
Drosophila melanogaster (Dme) dme10901 CG18271-PA
(FBgn0037263)
Danio rerio (Dre) dre13190 ENSDARP00000008426
Takifugu rubripes (Fru) fru17863 SINFRUP00000140913
Homo sapiens (Hsa) hsa11990 ENSP00000251303
(GIYD1)		 Q9BQ83-1
Homo sapiens (Hsa) hsa11941 ENSP00000328940
(GIYD1)		 Q9BQ83-1
Homo sapiens (Hsa) hsa11942 ENSP00000335205
Homo sapiens (Hsa) hsa11992 ENSP00000347739
(SULT1A3)		 B5MDJ5
Kluyveromyces lactis (Kla) kla4521 KLLA0F09713g
Mus musculus (Mmu) mmu25092 ENSMUSP00000032950
Mus musculus (Mmu) mmu25091 ENSMUSP00000058070
Neurospora crassa (Ncr) ncr1199 NCU01236.2
Oryza sativa (Osa) osa3241 2011.m00149
Oryza sativa (Osa) osa3745 2061.m00216
Oryza sativa (Osa) osa53447 6131.m00148
Oryza sativa (Osa) osa68434 7018.m00144
Rattus norvegicus (Rno) rno2986 ENSRNOP00000026231
(RGD:1311568)		 Q5PQP5
Rattus norvegicus (Rno) rno2987 ENSRNOP00000051190
Saccharomyces cerevisiae (Sce) sce502 YBR228W
(S000000432)
Schizosaccharomyces pombe (Spo) spo1293 SPAP27G11.15 Q9P7M3
Yarrowia lipolytica (Yli) yli6233 YALI0F21131g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
ISS
AthAt2g30350
GO:0005634 nucleus C
IC
SceS000000432
GO:0030874 nucleolar chromatin C
IDA
SpoSPAP27G11.15
GO:0033557 Slx1-Slx4 complex C
IDA
SpoSPAP27G11.15
IPI
SceS000000432
GO:0004518 nuclease activity F
ISS
AthAt2g30350
GO:0005515 protein binding F
IPI
SpoSPAP27G11.15
GO:0016894 endonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
3'-phosphomonoesters		 F
IDA
SpoSPAP27G11.15
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000000432
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPAP27G11.15
GO:0002119 nematode larval development P
IMP
CelWBGene00018909
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000000432
GO:0006281 DNA repair P
ISS
AthAt2g30350
GO:0006974 response to DNA damage stimulus P
IGI
SceS000000432
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00018909
GO:0031297 replication fork processing P
NAS
SpoSPAP27G11.15
GO:0034065 replication fork processing at rDNA
locus		 P
TAS
SpoSPAP27G11.15
GO:0040007 growth P
IMP
CelWBGene00018909
GO:0043007 maintenance of rDNA P
IMP
SpoSPAP27G11.15
GO:0045458 recombination within rDNA repeats P
IDA
SpoSPAP27G11.15

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAP27G11.15
(Q9P7M3)		 YBR228W
(S000000432)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000000432
GO:0030874 nucleolar chromatin C
IDA
SpoSPAP27G11.15
GO:0033557 Slx1-Slx4 complex C
IDA
SpoSPAP27G11.15
IPI
SceS000000432
GO:0005515 protein binding F
IPI
SpoSPAP27G11.15
GO:0016894 endonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
3'-phosphomonoesters		 F
IDA
SpoSPAP27G11.15
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000000432
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPAP27G11.15
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000000432
GO:0006974 response to DNA damage stimulus P
IGI
SceS000000432
GO:0031297 replication fork processing P
NAS
SpoSPAP27G11.15
GO:0034065 replication fork processing at rDNA
locus		 P
TAS
SpoSPAP27G11.15
GO:0043007 maintenance of rDNA P
IMP
SpoSPAP27G11.15
GO:0045458 recombination within rDNA repeats P
IDA
SpoSPAP27G11.15

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GO info in one table:

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