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Search term: YBR233W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PBP2
SGD link S000000437
Alternative ID YBR233W
Description RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length
Synonyms YBR233W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2190 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGPOORLY CHARACTERIZED PolyC-binding proteins alphaCP-1 and related KH domain proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g14170 GI:15223102
Arabidopsis thaliana (Ath) At1g51580 GI:15217969
Arabidopsis thaliana (Ath) At2g03110 GI:15227534
Arabidopsis thaliana (Ath) At2g22600 GI:15227251
Arabidopsis thaliana (Ath) At3g04610 GI:15229321
Arabidopsis thaliana (Ath) At4g18375 GI:15236863
Arabidopsis thaliana (Ath) At4g26000 GI:15236094
Arabidopsis thaliana (Ath) At5g09560 GI:15242441
Arabidopsis thaliana (Ath) At5g15270 GI:15242257
Arabidopsis thaliana (Ath) At5g46190 GI:15237393
Arabidopsis thaliana (Ath) At5g53060 GI:15237340
Arabidopsis thaliana (Ath) At5g64390 GI:15237687
Caenorhabditis elegans (Cel) CE27461 GI:17556751
Drosophila melanogaster (Dme) 7296507 GI:17737727 Q95SZ9
Homo sapiens (Hsa) Hs10092617 GI:10092617
Homo sapiens (Hsa) Hs14141166 GI:14141166 Q15366
Homo sapiens (Hsa) Hs14141168 GI:14141168 Q15366
Homo sapiens (Hsa) Hs14670369 GI:14670369 P57723
Homo sapiens (Hsa) Hs14670371 GI:14670371 P57723
Homo sapiens (Hsa) Hs22048229 GI:22048229
Homo sapiens (Hsa) Hs5453854 GI:5453854
Homo sapiens (Hsa) Hs9966803 GI:9966803 P57723
Saccharomyces cerevisiae (Sce) YBL032w
(S000000128)
GI:6319439 P38199
Saccharomyces cerevisiae (Sce) YBR233w
(S000000437)
GI:6319709 P38151
Schizosaccharomyces pombe (Spo) SPAC23D3.08 GI:19115457 Q09848
Schizosaccharomyces pombe (Spo) SPCC757.09c GI:19075184 O74919


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000784 nuclear chromosome, telomeric region C
IDA
SceS000000128
GO:0005575 cellular_component C
ND
AthAt5g53060
At1g14170
At4g26000
At4g18375
At2g03110
At5g15270
At5g09560
GO:0005634 nucleus C
IDA
AthAt3g04610
At5g64390
GO:0005685 U1 snRNP C
IDA
SpoSPAC23D3.08
GO:0005737 cytoplasm C
IDA
SceS000000437
S000000128
GO:0005829 cytosol C
IDA
SpoSPCC757.09c
GO:0003674 molecular_function F
ND
SceS000000437
GO:0003676 nucleic acid binding F
ISS
AthAt5g64390
At4g18375
At5g53060
At2g03110
At1g51580
At1g14170
At3g04610
At5g15270
At2g22600
At5g46190
At4g26000
At5g09560
GO:0003723 RNA binding F
ISS
AthAt5g64390
SpoSPAC23D3.08
RCA
SceS000000437
GO:0003729 mRNA binding F
IDA
SceS000000128
IPI
SpoSPCC757.09c
GO:0005515 protein binding F
IPI
SpoSPCC757.09c
GO:0000395 nuclear mRNA 5'-splice site recognition P
IC
SpoSPAC23D3.08
GO:0000398 nuclear mRNA splicing, via spliceosome P
IC
SpoSPAC23D3.08
GO:0006397 mRNA processing P
TAS
AthAt5g64390
GO:0006469 negative regulation of protein kinase
activity
P
IGI
SpoSPCC757.09c
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000000128
IPI
SceS000000128
GO:0008150 biological_process P
ND
AthAt4g18375
At1g14170
At2g03110
At2g22600
At5g46190
At5g53060
At5g09560
At5g15270
SceS000000437
GO:0008298 intracellular mRNA localization P
IMP
SceS000000128
IPI
SceS000000128
GO:0009911 positive regulation of flower development P
IMP
AthAt3g04610
GO:0010093 specification of floral organ identity P
IMP
AthAt5g64390
GO:0043409 negative regulation of MAPKKK cascade P
IGI
SpoSPCC757.09c
GO:0048255 mRNA stabilization P
IMP
SpoSPCC757.09c
GO:0048367 shoot development P
IMP
AthAt4g26000
GO:0048467 gynoecium development P
IMP
AthAt4g26000

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74536

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PCBP2 GI:193083108
Canis familiaris (Cfa) PCBP2 GI:73996213
Mus musculus (Mmu) Pcbp2
(MGI:108202)
GI:6997239 B2M1R7
Rattus norvegicus (Rno) Pcbp2
(RGD:1309626)
GI:61557337
Saccharomyces cerevisiae (Sce) PBP2
(S000000437)
GI:6319709 P38151
Kluyveromyces lactis (Kla) KLLA0F10703g GI:50311087
Eremothecium gossypii (Ego) AGOS_AFL018C GI:45198501
Magnaporthe grisea (Mgr) MGG_00514 GI:145611282
Neurospora crassa (Ncr) NCU09237.1 GI:32422371


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
NAS
HsaPCBP2
GO:0005737 cytoplasm C
IDA
HsaPCBP2
SceS000000437
NAS
HsaPCBP2
GO:0003674 molecular_function F
ND
SceS000000437
GO:0003723 RNA binding F
IDA
HsaPCBP2
RCA
SceS000000437
GO:0005515 protein binding F
IPI
HsaPCBP2
MmuMGI:108202
GO:0019899 enzyme binding F
IPI
HsaPCBP2
GO:0031625 ubiquitin protein ligase binding F
IPI
HsaPCBP2
GO:0008150 biological_process P
ND
SceS000000437
GO:0008380 RNA splicing P
EXP
HsaPCBP2
GO:0016071 mRNA metabolic process P
NAS
HsaPCBP2
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
IMP
HsaPCBP2
GO:0050687 negative regulation of defense response to
virus
P
IMP
HsaPCBP2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_548

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga300 ENSANGP00000002408
Anopheles gambiae (Aga) aga299 ENSANGP00000025834
Ashbya gossypii (Ago) ago2688 AER186C
Ashbya gossypii (Ago) ago3175 AFL018C
Arabidopsis thaliana (Ath) ath1489 At1g14170.1
Caenorhabditis elegans (Cel) cel17794 Y119D3B.17
(CE32746;
WBGene00003978)
Candida glabrata (Cgl) cgl1414 CAGL0F04257g
Candida glabrata (Cgl) cgl3828 CAGL0K07117g
Cryptococcus neoformans (Cne) cne585 163.m06249
Cryptococcus neoformans (Cne) cne3794 185.m02370
Debaryomyces hansenii (Dha) dha1003 DEHA0B07271g
Debaryomyces hansenii (Dha) dha4155 DEHA0E20603g
Drosophila melanogaster (Dme) dme10678 CG7437-PA
(FBgn0014362)
Drosophila melanogaster (Dme) dme10679 CG7437-PB
(FBgn0014362)
Drosophila melanogaster (Dme) dme10680 CG7437-PC
(FBgn0014362)
Danio rerio (Dre) dre17809 ENSDARP00000003163
(pcbp2)
Q7ZVK5
Danio rerio (Dre) dre23986 ENSDARP00000016097
(zgc:109966)
Q504B8
Danio rerio (Dre) dre23984 ENSDARP00000044385
(LOC562426)
Takifugu rubripes (Fru) fru29542 SINFRUP00000135170
Takifugu rubripes (Fru) fru29540 SINFRUP00000135175
Takifugu rubripes (Fru) fru29541 SINFRUP00000135179
Takifugu rubripes (Fru) fru31227 SINFRUP00000139720
Takifugu rubripes (Fru) fru31225 SINFRUP00000139722
Takifugu rubripes (Fru) fru9282 SINFRUP00000143932
Takifugu rubripes (Fru) fru21971 SINFRUP00000148719
Takifugu rubripes (Fru) fru21972 SINFRUP00000148721
Takifugu rubripes (Fru) fru9280 SINFRUP00000149540
Takifugu rubripes (Fru) fru31224 SINFRUP00000171255
Takifugu rubripes (Fru) fru31226 SINFRUP00000171668
Takifugu rubripes (Fru) fru31223 SINFRUP00000172835
Takifugu rubripes (Fru) fru9281 SINFRUP00000174355
Takifugu rubripes (Fru) fru31221 SINFRUP00000176509
Takifugu rubripes (Fru) fru31222 SINFRUP00000177203
Gallus gallus (Gga) gga10738 ENSGALP00000021449
Gallus gallus (Gga) gga10734 ENSGALP00000021450
(PCBP3)
Gallus gallus (Gga) gga10735 ENSGALP00000021451
(PCBP3)
Gallus gallus (Gga) gga10737 ENSGALP00000021453
(PCBP3)
Homo sapiens (Hsa) hsa17942 ENSP00000305556
(PCBP1)
Q15365
Homo sapiens (Hsa) hsa21077 ENSP00000329822
(PCBP3)
P57721-3
Homo sapiens (Hsa) hsa21075 ENSP00000330225
(PCBP3)
P57721-5
Homo sapiens (Hsa) hsa7578 ENSP00000352438
(PCBP2)
Q59HD4
Kluyveromyces lactis (Kla) kla3502 KLLA0E12309g
Kluyveromyces lactis (Kla) kla4567 KLLA0F10703g
Mus musculus (Mmu) mmu2371 ENSMUSP00000001148
(MGI:1890470)
P57722-1
Mus musculus (Mmu) mmu9757 ENSMUSP00000023811
Mus musculus (Mmu) mmu22258 ENSMUSP00000054863
(MGI:1345635)
P60335
Mus musculus (Mmu) mmu9755 ENSMUSP00000077509
(MGI:108202)
Q61990-3
Neurospora crassa (Ncr) ncr6076 NCU06251.2
Neurospora crassa (Ncr) ncr9003 NCU09237.2
Oryza sativa (Osa) osa9956 2741.m00156
Rattus norvegicus (Rno) rno17737 ENSRNOP00000001675
(RGD:1307430)
Q6AY48
Rattus norvegicus (Rno) rno21770 ENSRNOP00000023806
(RGD:1561319)
Rattus norvegicus (Rno) rno17736 ENSRNOP00000040960
(RGD:1307430)
Saccharomyces cerevisiae (Sce) sce158 YBL032W
(S000000128)
Saccharomyces cerevisiae (Sce) sce508 YBR233W
(S000000437)
Schizosaccharomyces pombe (Spo) spo3683 SPCC757.09c O74919
Yarrowia lipolytica (Yli) yli600 YALI0A18161g
Yarrowia lipolytica (Yli) yli2495 YALI0C19558g
Yarrowia lipolytica (Yli) yli3895 YALI0E00924g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000784 nuclear chromosome, telomeric region C
IDA
SceS000000128
GO:0005575 cellular_component C
ND
AthAt1g14170
GO:0005634 nucleus C
IC
DmeFBgn0014362
GO:0005737 cytoplasm C
IDA
SceS000000437
S000000128
GO:0005829 cytosol C
IDA
SpoSPCC757.09c
GO:0003674 molecular_function F
ND
SceS000000437
GO:0003676 nucleic acid binding F
ISS
AthAt1g14170
GO:0003723 RNA binding F
RCA
SceS000000437
TAS
MmuMGI:1345635
GO:0003729 mRNA binding F
IDA
SceS000000128
IPI
SpoSPCC757.09c
GO:0005515 protein binding F
IPI
MmuMGI:108202
MGI:1345635
SpoSPCC757.09c
GO:0008494 translation activator activity F
TAS
MmuMGI:1345635
GO:0017130 poly(C) RNA binding F
ISS
DmeFBgn0014362
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome
P
IMP
DmeFBgn0014362
GO:0006397 mRNA processing P
TAS
MmuMGI:1345635
GO:0006469 negative regulation of protein kinase
activity
P
IGI
SpoSPCC757.09c
GO:0007004 telomere maintenance via telomerase P
IMP
SceS000000128
IPI
SceS000000128
GO:0008150 biological_process P
ND
AthAt1g14170
SceS000000437
GO:0008298 intracellular mRNA localization P
IMP
SceS000000128
IPI
SceS000000128
GO:0043409 negative regulation of MAPKKK cascade P
IGI
SpoSPCC757.09c
GO:0045727 positive regulation of translation P
TAS
MmuMGI:1345635
GO:0048255 mRNA stabilization P
IMP
SpoSPCC757.09c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC757.09c
(O74919)
YBR233W
(S000000437)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000437
GO:0005829 cytosol C
IDA
SpoSPCC757.09c
GO:0003674 molecular_function F
ND
SceS000000437
GO:0003723 RNA binding F
RCA
SceS000000437
GO:0003729 mRNA binding F
IPI
SpoSPCC757.09c
GO:0005515 protein binding F
IPI
SpoSPCC757.09c
GO:0006469 negative regulation of protein kinase
activity
P
IGI
SpoSPCC757.09c
GO:0008150 biological_process P
ND
SceS000000437
GO:0043409 negative regulation of MAPKKK cascade P
IGI
SpoSPCC757.09c
GO:0048255 mRNA stabilization P
IMP
SpoSPCC757.09c

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s.khadayate@ucl.ac.uk