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Search term: YBR248C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HIS7
SGD link S000000452
Alternative ID YBR248C
Description Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor
Synonyms YBR248C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0623 A---YP-

KOGs classification KOGs description
METABOLISM Glutamine amidotransferase/cyclase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g26900 GI:15236905
Saccharomyces cerevisiae (Sce) YBR248c
(S000000452)		 GI:6319725 P33734
Schizosaccharomyces pombe (Spo) SPBC887.20c GI:19113286
Arabidopsis thaliana (Ath) At4g26900 GI:15236905
Saccharomyces cerevisiae (Sce) YBR248c
(S000000452)		 GI:6319725 P33734
Schizosaccharomyces pombe (Spo) SPBC887.20c GI:19113286


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000000452
GO:0009507 chloroplast C
IDA
AthAt4g26900
ISS
AthAt4g26900
GO:0000107 imidazoleglycerol-phosphate synthase
activity		 F
IDA
SceS000000452
IGI
AthAt4g26900
GO:0000105 histidine biosynthetic process P
IGI
AthAt4g26900
IMP
AthAt4g26900
SceS000000452
GO:0006082 organic acid metabolic process P
RCA
SceS000000452
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000000452
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000000452
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000452
GO:0009127 purine nucleoside monophosphate biosynthetic
process		 P
TAS
SceS000000452
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000452

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5433

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) his4
(SPBC418.01c)		 GI:63054793 O94303
Saccharomyces cerevisiae (Sce) HIS7
(S000000452)		 GI:6319725 P33734
Kluyveromyces lactis (Kla) KLLA0F06578g GI:50310713
Eremothecium gossypii (Ego) AGOS_AFL046W GI:45198473
Magnaporthe grisea (Mgr) MGG_00253 GI:39975201
Neurospora crassa (Ncr) NCU07156.1 GI:32413925
Arabidopsis thaliana (Ath) AT-HF GI:15236905
Oryza sativa (Osa) Os03g0256400 GI:115451995


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000000452
GO:0005634 nucleus C
IDA
SpoSPBC418.01c
GO:0005829 cytosol C
IDA
SpoSPBC418.01c
GO:0009507 chloroplast C
IDA
AthAT-HF
ISS
AthAT-HF
GO:0000107 imidazoleglycerol-phosphate synthase
activity		 F
IDA
SceS000000452
IGI
AthAT-HF
ISS
SpoSPBC418.01c
GO:0000105 histidine biosynthetic process P
IGI
AthAT-HF
IMP
AthAT-HF
SceS000000452
ISS
SpoSPBC418.01c
GO:0006082 organic acid metabolic process P
RCA
SceS000000452
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000000452
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000000452
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000452
GO:0009127 purine nucleoside monophosphate biosynthetic
process		 P
TAS
SceS000000452
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000452

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1134

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14081 ENSANGP00000001432
Ashbya gossypii (Ago) ago3147 AFL046W
Arabidopsis thaliana (Ath) ath20691 At4g26900.1
Candida glabrata (Cgl) cgl484 CAGL0C01595g
Cryptococcus neoformans (Cne) cne2429 181.m08464
Debaryomyces hansenii (Dha) dha201 DEHA0A04532g
Escherichia coli (Eco) eco1962 16129964
Escherichia coli (Eco) eco1964 16129966
Kluyveromyces lactis (Kla) kla4378 KLLA0F06578g
Neurospora crassa (Ncr) ncr6964 NCU07156.2
Oryza sativa (Osa) osa75436 7231.m00200
Saccharomyces cerevisiae (Sce) sce524 YBR248C
(S000000452)
Schizosaccharomyces pombe (Spo) spo1147 SPBC418.01c O94303
Yarrowia lipolytica (Yli) yli2007 YALI0C07128g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000000452
GO:0005634 nucleus C
IDA
SpoSPBC418.01c
GO:0005829 cytosol C
IDA
SpoSPBC418.01c
GO:0009507 chloroplast C
IDA
AthAt4g26900
ISS
AthAt4g26900
GO:0000107 imidazoleglycerol-phosphate synthase
activity		 F
IDA
SceS000000452
IGI
AthAt4g26900
ISS
SpoSPBC418.01c
GO:0000105 histidine biosynthetic process P
IGI
AthAt4g26900
IMP
AthAt4g26900
SceS000000452
ISS
SpoSPBC418.01c
GO:0006082 organic acid metabolic process P
RCA
SceS000000452
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000000452
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000000452
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000452
GO:0009127 purine nucleoside monophosphate biosynthetic
process		 P
TAS
SceS000000452
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000452

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC418.01c
(O94303)		 YBR248C
(S000000452)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
SceS000000452
GO:0005634 nucleus C
IDA
SpoSPBC418.01c
GO:0005829 cytosol C
IDA
SpoSPBC418.01c
GO:0000107 imidazoleglycerol-phosphate synthase
activity		 F
IDA
SceS000000452
ISS
SpoSPBC418.01c
GO:0000105 histidine biosynthetic process P
IMP
SceS000000452
ISS
SpoSPBC418.01c
GO:0006082 organic acid metabolic process P
RCA
SceS000000452
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000000452
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000000452
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000452
GO:0009127 purine nucleoside monophosphate biosynthetic
process		 P
TAS
SceS000000452
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000452

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