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Search term: YBR252W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DUT1
SGD link S000000456
Alternative ID YBR252W
Description dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability
Synonyms YBR252W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3370 ACDHYPE

KOGs classification KOGs description
METABOLISM dUTPase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g46940 GI:15232681
Caenorhabditis elegans (Cel) CE18855
(WBGene00010609)		 GI:17508109
Drosophila melanogaster (Dme) 7297803
(FBgn0013349)		 GI:19921126 Q9V3I1
Homo sapiens (Hsa) Hs17438047 GI:17438047
Homo sapiens (Hsa) Hs20469453 GI:20469453
Homo sapiens (Hsa) Hs4503423 GI:4503423 Q96Q81
Homo sapiens (Hsa) Hs7662538 GI:7662538
Saccharomyces cerevisiae (Sce) YBR252w
(S000000456)		 GI:6319729 P33317
Schizosaccharomyces pombe (Spo) SPAC644.05c GI:19114785 Q9P6Q5
Encephalitozoon cuniculi (Ecu) ECU05g0280 GI:19173565 Q8SS02
Encephalitozoon cuniculi (Ecu) ECU06g0430 GI:19074293 Q8SRS0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g46940
GO:0005634 nucleus C
IDA
SceS000000456
SpoSPAC644.05c
ISS
SpoSPAC644.05c
GO:0005737 cytoplasm C
IDA
SceS000000456
ISS
SpoSPAC644.05c
GO:0005829 cytosol C
IDA
SpoSPAC644.05c
GO:0004170 dUTP diphosphatase activity F
IMP
SceS000000456
ISS
AthAt3g46940
SpoSPAC644.05c
GO:0000003 reproduction P
IMP
CelWBGene00010609
GO:0000910 cytokinesis P
IMP
CelWBGene00010609
GO:0006281 DNA repair P
IMP
AthAt3g46940
GO:0009213 pyrimidine deoxyribonucleoside triphosphate
catabolic process		 P
IMP
SceS000000456
ISS
SpoSPAC644.05c
GO:0009394 2'-deoxyribonucleotide metabolic
process		 P
ISS
AthAt3g46940
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010609
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000456
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000456
GO:0051301 cell division P
IMP
CelWBGene00010609

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31475

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DUT GI:70906441
Pan troglodytes (Ptr) DUT GI:114656884
Canis familiaris (Cfa) DUT GI:74000610
Mus musculus (Mmu) Dut
(MGI:1346051)		 GI:21281687 Q8VCG1
Gallus gallus (Gga) DUT GI:118095767
Drosophila melanogaster (Dme) dUTPase
(FBgn0013349)		 GI:19921126 Q9V3I1
Anopheles gambiae (Aga) AgaP_AGAP010159 GI:119114540
Caenorhabditis elegans (Cel) dut-1
(CE18855;
WBGene00010609)		 GI:71988561
Schizosaccharomyces pombe (Spo) SPAC644.05c GI:19114785 Q9P6Q5
Saccharomyces cerevisiae (Sce) DUT1
(S000000456)		 GI:6319729 P33317
Kluyveromyces lactis (Kla) KLLA0D15697g GI:50307545
Eremothecium gossypii (Ego) AGOS_AGR249C GI:45201345
Magnaporthe grisea (Mgr) MGG_00516 GI:145611280
Arabidopsis thaliana (Ath) AT3G46940 GI:15232681
Oryza sativa (Osa) Os03g0669100 GI:115454523


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g46940
GO:0005634 nucleus C
IDA
SceS000000456
SpoSPAC644.05c
ISS
SpoSPAC644.05c
GO:0005737 cytoplasm C
IDA
SceS000000456
ISS
SpoSPAC644.05c
GO:0005739 mitochondrion C
IDA
MmuMGI:1346051
GO:0005829 cytosol C
IDA
SpoSPAC644.05c
GO:0004170 dUTP diphosphatase activity F
IMP
SceS000000456
ISS
AthAt3g46940
SpoSPAC644.05c
GO:0005515 protein binding F
IPI
HsaDUT
GO:0000003 reproduction P
IMP
CelWBGene00010609
GO:0000910 cytokinesis P
IMP
CelWBGene00010609
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
TAS
HsaDUT
GO:0006260 DNA replication P
TAS
HsaDUT
GO:0006281 DNA repair P
IMP
AthAt3g46940
GO:0009213 pyrimidine deoxyribonucleoside triphosphate
catabolic process		 P
IMP
SceS000000456
ISS
SpoSPAC644.05c
GO:0009394 2'-deoxyribonucleotide metabolic
process		 P
ISS
AthAt3g46940
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010609
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000456
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000456
GO:0051301 cell division P
IMP
CelWBGene00010609

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_867

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14315 ENSANGP00000001952
Anopheles gambiae (Aga) aga12454 ENSANGP00000012604
Ashbya gossypii (Ago) ago4560 AGR249C
Arabidopsis thaliana (Ath) ath15975 At3g46940.1
Caenorhabditis elegans (Cel) cel12062 K07A1.2
(CE18855;
WBGene00010609)
Candida glabrata (Cgl) cgl4492 CAGL0L09581g
Cryptococcus neoformans (Cne) cne1739 164.m02111
Dictyostelium discoideum (Ddi) ddi13469 DDB0230111
Debaryomyces hansenii (Dha) dha3033 DEHA0D16357g
Drosophila melanogaster (Dme) dme1952 CG4584-PA
(FBgn0013349)
Drosophila melanogaster (Dme) dme1951 CG4584-PB
(FBgn0013349)
Danio rerio (Dre) dre27468 ENSDARP00000020086
Escherichia coli (Eco) eco3520 16131511
Encephalitozoon cuniculi (Ecu) ecu1520 19074293
Takifugu rubripes (Fru) fru7813 SINFRUP00000133083
Gallus gallus (Gga) gga3911 ENSGALP00000007930
(DUT)		 Q5ZKJ3
Homo sapiens (Hsa) hsa10621 ENSP00000249783
(DUT)		 P33316-1
Kluyveromyces lactis (Kla) kla2751 KLLA0D15697g
Mus musculus (Mmu) mmu15408 ENSMUSP00000057854
(MGI:1346051)		 Q9CQ43
Mus musculus (Mmu) mmu15407 ENSMUSP00000080767
(MGI:1346051)		 Q8VCG1
Neurospora crassa (Ncr) ncr10420 NCU10893.2
Oryza sativa (Osa) osa63469 6737.m00164
Oryza sativa (Osa) osa63512 6737.m00189
Plasmodium falciparum (Pfa) pfa733 PF11_0282
Rattus norvegicus (Rno) rno19616 ENSRNOP00000009549
(RGD:620849)		 P70583
Rattus norvegicus (Rno) rno466 ENSRNOP00000023387
Saccharomyces cerevisiae (Sce) sce528 YBR252W
(S000000456)
Schizosaccharomyces pombe (Spo) spo1540 SPAC644.05c Q9P6Q5
Yarrowia lipolytica (Yli) yli6159 YALI0F19448g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g46940
PfaPF11_0282
GO:0005634 nucleus C
IDA
SceS000000456
SpoSPAC644.05c
ISS
SpoSPAC644.05c
GO:0005737 cytoplasm C
IDA
SceS000000456
ISS
SpoSPAC644.05c
GO:0005739 mitochondrion C
IDA
MmuMGI:1346051
GO:0005829 cytosol C
IDA
SpoSPAC644.05c
GO:0004170 dUTP diphosphatase activity F
IMP
SceS000000456
ISS
AthAt3g46940
PfaPF11_0282
SpoSPAC644.05c
GO:0000003 reproduction P
IMP
CelWBGene00010609
GO:0000910 cytokinesis P
IMP
CelWBGene00010609
GO:0006260 DNA replication P
ISS
PfaPF11_0282
GO:0006281 DNA repair P
IMP
AthAt3g46940
GO:0006399 tRNA metabolic process P
ISS
PfaPF11_0282
GO:0009213 pyrimidine deoxyribonucleoside triphosphate
catabolic process		 P
IMP
SceS000000456
ISS
SpoSPAC644.05c
GO:0009394 2'-deoxyribonucleotide metabolic
process		 P
ISS
AthAt3g46940
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010609
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000456
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000456
GO:0051301 cell division P
IMP
CelWBGene00010609

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC644.05c
(Q9P6Q5)		 YBR252W
(S000000456)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000456
SpoSPAC644.05c
ISS
SpoSPAC644.05c
GO:0005737 cytoplasm C
IDA
SceS000000456
ISS
SpoSPAC644.05c
GO:0005829 cytosol C
IDA
SpoSPAC644.05c
GO:0004170 dUTP diphosphatase activity F
IMP
SceS000000456
ISS
SpoSPAC644.05c
GO:0009213 pyrimidine deoxyribonucleoside triphosphate
catabolic process		 P
IMP
SceS000000456
ISS
SpoSPAC644.05c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000456
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000000456

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GO info in one table:

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