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Search term: YBR254C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TRS20
SGD link S000000458
Alternative ID YBR254C
Description One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder
Synonyms YBR254C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3487 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING TRAPP 20 K subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g80500 GI:15220150
Caenorhabditis elegans (Cel) CE14652
(WBGene00021046)		 GI:17570257 O02173
Drosophila melanogaster (Dme) 7294178 GI:7294178
Homo sapiens (Hsa) Hs7657548 GI:7657548 O14582
Homo sapiens (Hsa) Hs17433405 GI:17433405
Saccharomyces cerevisiae (Sce) YBR254c
(S000000458)		 GI:6319731 P38334
Schizosaccharomyces pombe (Spo) SPBC11G11.04 GI:19112514 Q9USZ5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC11G11.04
GO:0005801 cis-Golgi network C
IC
SpoSPBC11G11.04
GO:0005829 cytosol C
IDA
SpoSPBC11G11.04
GO:0030008 TRAPP complex C
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0003674 molecular_function F
ND
AthAt1g80500
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0006886 intracellular protein transport P
IC
SpoSPBC11G11.04
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000000458
ISS
SpoSPBC11G11.04
GO:0032313 regulation of Rab GTPase activity P
IC
SpoSPBC11G11.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5436

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TRAPPC2 GI:58533179
Pan troglodytes (Ptr) TRAPPC2 GI:114687808
Canis familiaris (Cfa) TRAPPC2 GI:57111631
Mus musculus (Mmu) Trappc2
(MGI:1913476)		 GI:13384832 Q5J9A9
Rattus norvegicus (Rno) Trappc2 GI:68163405
Gallus gallus (Gga) TRAPPC2 GI:57525493
Drosophila melanogaster (Dme) CG5161
(FBgn0036573)		 GI:24665053
Anopheles gambiae (Aga) AgaP_AGAP002528 GI:118782646
Caenorhabditis elegans (Cel) sedl-1
(CE14652;
WBGene00021046)		 GI:17570257 O02173
Schizosaccharomyces pombe (Spo) trs20
(SPBC11G11.04)		 GI:19112514 Q9USZ5
Saccharomyces cerevisiae (Sce) TRS20
(S000000458)		 GI:6319731 P38334
Kluyveromyces lactis (Kla) KLLA0D15763g GI:50307551
Eremothecium gossypii (Ego) AGOS_AGR246W GI:45201342
Magnaporthe grisea (Mgr) MGG_06294 GI:39976783
Arabidopsis thaliana (Ath) AT1G80500 GI:145337812
Oryza sativa (Osa) Os02g0613600 GI:115447281
Plasmodium falciparum (Pfa) PF13_0174 GI:124513396


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC11G11.04
GO:0005801 cis-Golgi network C
IC
SpoSPBC11G11.04
GO:0005829 cytosol C
IDA
SpoSPBC11G11.04
GO:0030008 TRAPP complex C
IDA
MmuMGI:1913476
SceS000000458
ISS
SpoSPBC11G11.04
GO:0003674 molecular_function F
ND
AthAt1g80500
GO:0005515 protein binding F
IPI
HsaTRAPPC2
MmuMGI:1913476
GO:0008134 transcription factor binding F
IPI
HsaTRAPPC2
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0001501 skeletal system development P
TAS
HsaTRAPPC2
GO:0006355 regulation of transcription, DNA-dependent P
IDA
HsaTRAPPC2
GO:0006886 intracellular protein transport P
IC
SpoSPBC11G11.04
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000000458
ISS
SpoSPBC11G11.04
NAS
HsaTRAPPC2
GO:0008150 biological_process P
ND
MmuMGI:1913476
GO:0032313 regulation of Rab GTPase activity P
IC
SpoSPBC11G11.04
GO:0033227 dsRNA transport P
IMP
DmeFBgn0036573

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2390

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4728 ENSANGP00000022082
Ashbya gossypii (Ago) ago4557 AGR246W
Arabidopsis thaliana (Ath) ath7437 At1g80500.1
Caenorhabditis elegans (Cel) cel17091 W05H7.3
(CE14652;
WBGene00021046)
Candida glabrata (Cgl) cgl887 CAGL0D05346g
Cryptococcus neoformans (Cne) cne4087 185.m02759
Dictyostelium discoideum (Ddi) ddi4774 DDB0205013
Debaryomyces hansenii (Dha) dha3023 DEHA0D16148g
Drosophila melanogaster (Dme) dme9731 CG5161-PA
(FBgn0036573)
Takifugu rubripes (Fru) fru6420 SINFRUP00000134936
Gallus gallus (Gga) gga2429 ENSGALP00000026710
(TRAPPC2)		 Q5ZKP4
Homo sapiens (Hsa) hsa17230 ENSP00000310153
Homo sapiens (Hsa) hsa32457 ENSP00000350472
Homo sapiens (Hsa) hsa32455 ENSP00000350966
(TRAPPC2)		 O14582-1
Homo sapiens (Hsa) hsa32456 ENSP00000352708
(TRAPPC2)		 O14582-1
Kluyveromyces lactis (Kla) kla2754 KLLA0D15763g
Mus musculus (Mmu) mmu3607 ENSMUSP00000007921
(MGI:1913300)		 Q8R3W2
Oryza sativa (Osa) osa38668 4900.m00123
Oryza sativa (Osa) osa81971 8174.m00112
Oryza sativa (Osa) osa85704 8336.m00148
Plasmodium falciparum (Pfa) pfa4361 PF13_0174
Rattus norvegicus (Rno) rno4938 ENSRNOP00000006006
Saccharomyces cerevisiae (Sce) sce530 YBR254C
(S000000458)
Schizosaccharomyces pombe (Spo) spo1099 SPBC11G11.04 Q9USZ5
Yarrowia lipolytica (Yli) yli4004 YALI0E03520g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1913300
GO:0005634 nucleus C
IDA
SpoSPBC11G11.04
GO:0005801 cis-Golgi network C
IC
SpoSPBC11G11.04
GO:0005829 cytosol C
IDA
SpoSPBC11G11.04
GO:0030008 TRAPP complex C
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0003674 molecular_function F
ND
AthAt1g80500
MmuMGI:1913300
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0006886 intracellular protein transport P
IC
SpoSPBC11G11.04
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000000458
ISS
SpoSPBC11G11.04
GO:0008150 biological_process P
ND
MmuMGI:1913300
GO:0032313 regulation of Rab GTPase activity P
IC
SpoSPBC11G11.04
GO:0033227 dsRNA transport P
IMP
DmeFBgn0036573

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC11G11.04
(Q9USZ5)		 YBR254C
(S000000458)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC11G11.04
GO:0005801 cis-Golgi network C
IC
SpoSPBC11G11.04
GO:0005829 cytosol C
IDA
SpoSPBC11G11.04
GO:0030008 TRAPP complex C
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IDA
SceS000000458
ISS
SpoSPBC11G11.04
GO:0006886 intracellular protein transport P
IC
SpoSPBC11G11.04
GO:0006888 ER to Golgi vesicle-mediated transport P
IMP
SceS000000458
ISS
SpoSPBC11G11.04
GO:0032313 regulation of Rab GTPase activity P
IC
SpoSPBC11G11.04

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s.khadayate@ucl.ac.uk