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Search term: YBR278W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DPB3
SGD link S000000482
Alternative ID YBR278W
Description Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle
Synonyms YBR278W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1658 -CDHY--

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA polymerase epsilon, subunit C

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs9845281 GI:9845281
Caenorhabditis elegans (Cel) CE22389
(WBGene00013150)		 GI:17537433 Q9NAC5
Drosophila melanogaster (Dme) 7291416 GI:7291416
Saccharomyces cerevisiae (Sce) YBR278w
(S000000482)		 GI:6319754 P27344
Saccharomyces cerevisiae (Sce) YJL065c
(S000003601)		 GI:6322397 P40366


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003601
GO:0005657 replication fork C
TAS
SceS000000482
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000000482
GO:0008623 chromatin accessibility complex C
IPI
SceS000003601
GO:0003674 molecular_function F
ND
SceS000003601
GO:0003690 double-stranded DNA binding F
IDA
SceS000000482
GO:0003887 DNA-directed DNA polymerase activity F
TAS
SceS000000482
GO:0006272 leading strand elongation P
TAS
SceS000000482
GO:0006273 lagging strand elongation P
TAS
SceS000000482
GO:0006289 nucleotide-excision repair P
TAS
SceS000000482
GO:0006298 mismatch repair P
TAS
SceS000000482
GO:0006348 chromatin silencing at telomere P
IMP
SceS000003601
S000000482

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2947

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga326 ENSANGP00000011425
Anopheles gambiae (Aga) aga2876 ENSANGP00000019118
Anopheles gambiae (Aga) aga325 ENSANGP00000022465
Ashbya gossypii (Ago) ago2347 AEL159W
Arabidopsis thaliana (Ath) ath795 At1g07980.1
Caenorhabditis elegans (Cel) cel19632 Y53F4B.3
(CE22389;
WBGene00013150)
Candida glabrata (Cgl) cgl351 CAGL0B03355g
Cryptococcus neoformans (Cne) cne4453 177.m03206
Dictyostelium discoideum (Ddi) ddi11626 DDB0216394
Debaryomyces hansenii (Dha) dha982 DEHA0B06820g
Drosophila melanogaster (Dme) dme6535 CG11301-PA
(FBgn0034726)
Drosophila melanogaster (Dme) dme17541 CG15736-PA
(FBgn0043001)
Danio rerio (Dre) dre2314 ENSDARP00000016362
(zgc:110337)		 Q503Q5
Takifugu rubripes (Fru) fru2249 SINFRUP00000129705
Takifugu rubripes (Fru) fru25067 SINFRUP00000164550
Homo sapiens (Hsa) hsa30769 ENSP00000220913
(CHRAC1)		 Q9NRG0
Homo sapiens (Hsa) hsa18062 ENSP00000233699
Mus musculus (Mmu) mmu22159 ENSMUSP00000032121
Mus musculus (Mmu) mmu31430 ENSMUSP00000077299
Mus musculus (Mmu) mmu9083 ENSMUSP00000078055
Oryza sativa (Osa) osa54085 6301.m00198
Rattus norvegicus (Rno) rno21677 ENSRNOP00000008005
(RGD:1307793)		 B2RYN4
Rattus norvegicus (Rno) rno27185 ENSRNOP00000012121
(RGD:1309321)
Saccharomyces cerevisiae (Sce) sce555 YBR278W
(S000000482)
Yarrowia lipolytica (Yli) yli111 YALI0A02937g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005657 replication fork C
TAS
SceS000000482
GO:0008622 epsilon DNA polymerase complex C
IC
DmeFBgn0034726
IDA
SceS000000482
GO:0008623 chromatin accessibility complex C
IDA
DmeFBgn0043001
NAS
DmeFBgn0043001
GO:0003690 double-stranded DNA binding F
IDA
SceS000000482
GO:0003700 transcription factor activity F
ISS
AthAt1g07980
GO:0003887 DNA-directed DNA polymerase activity F
ISS
DmeFBgn0034726
TAS
SceS000000482
GO:0046982 protein heterodimerization activity F
IPI
DmeFBgn0043001
GO:0006260 DNA replication P
IC
DmeFBgn0034726
GO:0006272 leading strand elongation P
TAS
SceS000000482
GO:0006273 lagging strand elongation P
TAS
SceS000000482
GO:0006289 nucleotide-excision repair P
TAS
SceS000000482
GO:0006298 mismatch repair P
TAS
SceS000000482
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000482
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0034726
FBgn0043001
GO:0045449 regulation of transcription P
TAS
AthAt1g07980

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC17G8.03c
(Q10315)		 YBR278W
(S000000482)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
NAS
SpoSPAC17G8.03c
GO:0005634 nucleus C
IDA
SpoSPAC17G8.03c
GO:0005657 replication fork C
TAS
SceS000000482
GO:0005829 cytosol C
IDA
SpoSPAC17G8.03c
GO:0008622 epsilon DNA polymerase complex C
IDA
SceS000000482
IPI
SpoSPAC17G8.03c
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPAC17G8.03c
GO:0043596 nuclear replication fork C
IC
SpoSPAC17G8.03c
GO:0003690 double-stranded DNA binding F
IDA
SceS000000482
GO:0003887 DNA-directed DNA polymerase activity F
TAS
SceS000000482
SpoSPAC17G8.03c
GO:0005515 protein binding F
IPI
SpoSPAC17G8.03c
GO:0006261 DNA-dependent DNA replication P
IMP
SpoSPAC17G8.03c
GO:0006272 leading strand elongation P
TAS
SceS000000482
GO:0006273 lagging strand elongation P
TAS
SceS000000482
GO:0006289 nucleotide-excision repair P
TAS
SceS000000482
GO:0006298 mismatch repair P
TAS
SceS000000482
GO:0006348 chromatin silencing at telomere P
IMP
SceS000000482
GO:0034613 cellular protein localization P
IGI
SpoSPAC17G8.03c

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