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Search term: YBR281C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DUG2
SGD link S000000485
Alternative ID YBR281C
Description Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)
Synonyms YBR281C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56064

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) DUG2
(S000000485)
GI:6319758 P38149
Kluyveromyces lactis (Kla) KLLA0F01991g GI:50310301
Eremothecium gossypii (Ego) AGOS_AEL154C GI:45190453
Magnaporthe grisea (Mgr) MGG_04227 GI:145607415
Neurospora crassa (Ncr) NCU05622.1 GI:32409993


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000485
GO:0005737 cytoplasm C
IDA
SceS000000485
GO:0008233 peptidase activity F
IGI
SceS000000485
GO:0008242 omega peptidase activity F
IGI
SceS000000485
GO:0006751 glutathione catabolic process P
IMP
SceS000000485

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11646

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2352 AEL154C
Candida glabrata (Cgl) cgl348 CAGL0B03289g
Cryptococcus neoformans (Cne) cne1495 180.m00451
Debaryomyces hansenii (Dha) dha3566 DEHA0E07337g
Kluyveromyces lactis (Kla) kla4169 KLLA0F01991g
Neurospora crassa (Ncr) ncr5463 NCU05622.2
Saccharomyces cerevisiae (Sce) sce558 YBR281C
(S000000485)
Yarrowia lipolytica (Yli) yli5610 YALI0F06336g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000000485
GO:0005737 cytoplasm C
IDA
SceS000000485
GO:0008233 peptidase activity F
IGI
SceS000000485
GO:0008242 omega peptidase activity F
IGI
SceS000000485
GO:0006751 glutathione catabolic process P
IMP
SceS000000485

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s.khadayate@ucl.ac.uk