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Search term: YBR290W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BSD2
SGD link S000000494
Alternative ID YBR290W
Description Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification
Synonyms YBR290W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4812 --DHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Golgi-associated protein/Nedd4 WW domain-binding protein

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7293957 GI:7293957
Homo sapiens (Hsa) Hs13386480
(NDFIP1)		 GI:13386480 Q9BT67
Homo sapiens (Hsa) Hs14754744 GI:14754744
Saccharomyces cerevisiae (Sce) YBR290w
(S000000494)		 GI:6319767 P38356
Schizosaccharomyces pombe (Spo) SPAC328.07c GI:19115121 Q9P3T9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000000494
GO:0005783 endoplasmic reticulum C
IDA
SceS000000494
ISS
SpoSPAC328.07c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC328.07c
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaNDFIP1
GO:0003674 molecular_function F
ND
SpoSPAC328.07c
GO:0004871 signal transducer activity F
IMP
HsaNDFIP1
GO:0005515 protein binding F
IDA
SceS000000494
IPI
HsaNDFIP1
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000000494
GO:0006623 protein targeting to vacuole P
IMP
SceS000000494
ISS
SpoSPAC328.07c
GO:0006875 cellular metal ion homeostasis P
IC
SpoSPAC328.07c
GO:0006879 cellular iron ion homeostasis P
IMP
HsaNDFIP1
GO:0010629 negative regulation of gene expression P
IMP
HsaNDFIP1
GO:0010959 regulation of metal ion transport P
ISS
SpoSPAC328.07c
GO:0030001 metal ion transport P
IMP
SceS000000494
GO:0031398 positive regulation of protein
ubiquitination		 P
IMP
HsaNDFIP1
GO:0032410 negative regulation of transporter
activity		 P
IMP
HsaNDFIP1
GO:0033554 cellular response to stress P
IEP
SpoSPAC328.07c
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB
cascade		 P
IMP
HsaNDFIP1
GO:0051224 negative regulation of protein
transport		 P
IMP
HsaNDFIP1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104070

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) BSD2
(S000000494)		 GI:6319767 P38356
Kluyveromyces lactis (Kla) KLLA0E18832g GI:50309573
Eremothecium gossypii (Ego) AGOS_AGL063C GI:45201033


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000000494
GO:0005783 endoplasmic reticulum C
IDA
SceS000000494
GO:0005515 protein binding F
IDA
SceS000000494
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000000494
GO:0006623 protein targeting to vacuole P
IMP
SceS000000494
GO:0030001 metal ion transport P
IMP
SceS000000494

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13169

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4248 AGL063C
Candida glabrata (Cgl) cgl4165 CAGL0L02101g
Cryptococcus neoformans (Cne) cne1611 164.m02136
Debaryomyces hansenii (Dha) dha4933 DEHA0F12408g
Kluyveromyces lactis (Kla) kla3797 KLLA0E18832g
Neurospora crassa (Ncr) ncr4929 NCU05077.2
Saccharomyces cerevisiae (Sce) sce567 YBR290W
(S000000494)
Schizosaccharomyces pombe (Spo) spo2596 SPAC328.07c Q9P3T9
Yarrowia lipolytica (Yli) yli6442 YALI0F26301g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000000494
GO:0005783 endoplasmic reticulum C
IDA
SceS000000494
ISS
SpoSPAC328.07c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC328.07c
GO:0003674 molecular_function F
ND
SpoSPAC328.07c
GO:0005515 protein binding F
IDA
SceS000000494
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000000494
GO:0006623 protein targeting to vacuole P
IMP
SceS000000494
ISS
SpoSPAC328.07c
GO:0006875 cellular metal ion homeostasis P
IC
SpoSPAC328.07c
GO:0010959 regulation of metal ion transport P
ISS
SpoSPAC328.07c
GO:0030001 metal ion transport P
IMP
SceS000000494
GO:0033554 cellular response to stress P
IEP
SpoSPAC328.07c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC328.07c
(Q9P3T9)		 YBR290W
(S000000494)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000000494
GO:0005783 endoplasmic reticulum C
IDA
SceS000000494
ISS
SpoSPAC328.07c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC328.07c
GO:0003674 molecular_function F
ND
SpoSPAC328.07c
GO:0005515 protein binding F
IDA
SceS000000494
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000000494
GO:0006623 protein targeting to vacuole P
IMP
SceS000000494
ISS
SpoSPAC328.07c
GO:0006875 cellular metal ion homeostasis P
IC
SpoSPAC328.07c
GO:0010959 regulation of metal ion transport P
ISS
SpoSPAC328.07c
GO:0030001 metal ion transport P
IMP
SceS000000494
GO:0033554 cellular response to stress P
IEP
SpoSPAC328.07c

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