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Search term: YCL057W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRD1
SGD link S000000562
Alternative ID YCL057W
Description Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins
Synonyms YCL057W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2089 ACDHY--

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Metalloendopeptidase family - saccharolysin & thimet oligopeptidase

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs14149738
(NLN)
GI:14149738 Q9BQD0
Homo sapiens (Hsa) Hs4507491
(THOP1)
GI:4507491 P52888
Arabidopsis thaliana (Ath) At1g67700 GI:11072026
Saccharomyces cerevisiae (Sce) YCL057w
(S000000562)
GI:6319793 P25375
Arabidopsis thaliana (Ath) At5g65620 GI:8978290
Arabidopsis thaliana (Ath) At5g10540 GI:11279605
Drosophila melanogaster (Dme) 7301239 GI:7301239
Caenorhabditis elegans (Cel) CE16734 GI:17544576


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000000562
TAS
SceS000000562
GO:0005739 mitochondrion C
IDA
SceS000000562
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000000562
GO:0005829 cytosol C
IDA
AthAt5g10540
At5g65620
GO:0009507 chloroplast C
IDA
AthAt5g65620
At5g10540
At1g67700
GO:0009570 chloroplast stroma C
IDA
AthAt5g65620
GO:0009941 chloroplast envelope C
IDA
AthAt1g67700
GO:0048046 apoplast C
IDA
AthAt5g10540
GO:0003674 molecular_function F
ND
AthAt1g67700
GO:0004222 metalloendopeptidase activity F
IDA
SceS000000562
IMP
SceS000000562
ISS
AthAt5g65620
At5g10540
SceS000000562
GO:0005515 protein binding F
IPI
HsaTHOP1
GO:0006508 proteolysis P
IDA
SceS000000562
IMP
SceS000000562
ISS
AthAt5g10540
At5g65620
GO:0008150 biological_process P
ND
AthAt1g67700
GO:0046686 response to cadmium ion P
IEP
AthAt5g10540

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
69315

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NLN GI:14149738 Q9BQD0
Pan troglodytes (Ptr) NLN GI:114600002
Canis familiaris (Cfa) NLN GI:73949993
Mus musculus (Mmu) Nln
(MGI:1923055)
GI:28077051 Q3TB65
Rattus norvegicus (Rno) Nln
(RGD:621518)
GI:50054266
Gallus gallus (Gga) NLN GI:118103869
Saccharomyces cerevisiae (Sce) PRD1
(S000000562)
GI:6319793 P25375
Kluyveromyces lactis (Kla) KLLA0C00572g GI:50304529
Magnaporthe grisea (Mgr) MGG_04858 GI:145602498
Neurospora crassa (Ncr) NCU06618.1 GI:32411985
Arabidopsis thaliana (Ath) AT1G67690 GI:18408838
Oryza sativa (Osa) Os01g0902200 GI:115441673


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAT1G67690
GO:0005737 cytoplasm C
IDA
SceS000000562
TAS
SceS000000562
GO:0005739 mitochondrion C
IDA
MmuMGI:1923055
SceS000000562
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000000562
GO:0003674 molecular_function F
ND
MmuMGI:1923055
GO:0004222 metalloendopeptidase activity F
IDA
SceS000000562
IMP
SceS000000562
ISS
AthAT1G67690
SceS000000562
GO:0006508 proteolysis P
IDA
SceS000000562
IMP
SceS000000562
ISS
AthAT1G67690
GO:0008150 biological_process P
ND
MmuMGI:1923055

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1376

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga14848 ENSANGP00000012412
Ashbya gossypii (Ago) ago4716 AGR405C
Ashbya gossypii (Ago) ago4717 AGR406C
Arabidopsis thaliana (Ath) ath6004 At1g67690.1
Arabidopsis thaliana (Ath) ath23256 At5g10540.1
Arabidopsis thaliana (Ath) ath28717 At5g65620.1
Caenorhabditis elegans (Cel) cel22000 ZK550.3
(CE37464;
WBGene00013997)
Candida glabrata (Cgl) cgl222 CAGL0B00418g
Dictyostelium discoideum (Ddi) ddi10112 DDB0219735
Drosophila melanogaster (Dme) dme14330 CG11771-PA
(FBgn0039252)
Danio rerio (Dre) dre1385 ENSDARP00000015197
(thop1)
Q5XIZ1
Escherichia coli (Eco) eco1498 16129497
Escherichia coli (Eco) eco3377 16131370
Takifugu rubripes (Fru) fru5918 SINFRUP00000139045
Takifugu rubripes (Fru) fru3360 SINFRUP00000165285
Gallus gallus (Gga) gga27568 ENSGALP00000023775
Gallus gallus (Gga) gga27569 ENSGALP00000023776
(NLN)
Homo sapiens (Hsa) hsa15284 ENSP00000304467
(THOP1)
P52888
Homo sapiens (Hsa) hsa25305 ENSP00000339283
(NLN)
Q96K48
Kluyveromyces lactis (Kla) kla1218 KLLA0C00572g
Mus musculus (Mmu) mmu2557 ENSMUSP00000005057
(MGI:1354165)
Q8C1A5
Mus musculus (Mmu) mmu7492 ENSMUSP00000022223
(MGI:1923055)
Neurospora crassa (Ncr) ncr6436 NCU06618.2
Oryza sativa (Osa) osa6639 2458.m00109
Oryza sativa (Osa) osa32189 4401.m00151
Rattus norvegicus (Rno) rno15456 ENSRNOP00000015853
(RGD:621518)
Rattus norvegicus (Rno) rno26210 ENSRNOP00000027045
(RGD:68330)
P24155
Saccharomyces cerevisiae (Sce) sce638 YCL057W
(S000000562)
Yarrowia lipolytica (Yli) yli5665 YALI0F07667g
Yarrowia lipolytica (Yli) yli6226 YALI0F20988g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAT1G67690
GO:0005625 soluble fraction C
ISO
MmuMGI:1354165
GO:0005737 cytoplasm C
IDA
SceS000000562
TAS
SceS000000562
GO:0005739 mitochondrion C
IDA
MmuMGI:1923055
SceS000000562
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000000562
GO:0005829 cytosol C
IDA
AthAt5g10540
At5g65620
GO:0009507 chloroplast C
IDA
AthAt5g65620
At5g10540
GO:0009570 chloroplast stroma C
IDA
AthAt5g65620
GO:0048046 apoplast C
IDA
AthAt5g10540
GO:0003674 molecular_function F
ND
MmuMGI:1923055
GO:0004222 metalloendopeptidase activity F
IDA
MmuMGI:1354165
SceS000000562
IMP
SceS000000562
ISS
AthAt5g65620
At5g10540
AT1G67690
DmeFBgn0039252
SceS000000562
GO:0008233 peptidase activity F
ISO
MmuMGI:1354165
GO:0042277 peptide binding F
ISO
MmuMGI:1354165
GO:0000003 reproduction P
IMP
CelWBGene00013997
GO:0006508 proteolysis P
IDA
SceS000000562
IMP
SceS000000562
ISS
AthAt5g10540
AT1G67690
At5g65620
GO:0006518 peptide metabolic process P
IDA
MmuMGI:1354165
GO:0007243 intracellular protein kinase cascade P
IDA
MmuMGI:1354165
GO:0008150 biological_process P
ND
MmuMGI:1923055
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00013997
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00013997
GO:0046686 response to cadmium ion P
IEP
AthAt5g10540

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s.khadayate@ucl.ac.uk