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Search term: YCL061C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MRC1
SGD link S000000566
Alternative ID YCL061C
Description S-phase checkpoint protein required for DNA replication; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; protects uncapped telomeres
Synonyms YCL061C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38493

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MRC1
(S000000566)		 GI:10383754
Kluyveromyces lactis (Kla) KLLA0C00484g GI:50304521
Eremothecium gossypii (Ego) AGOS_AFR745W GI:45199265


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000000566
GO:0005634 nucleus C
IDA
SceS000000566
GO:0031298 replication fork protection complex C
IDA
SceS000000566
GO:0043596 nuclear replication fork C
IDA
SceS000000566
GO:0003674 molecular_function F
ND
SceS000000566
GO:0000076 DNA replication checkpoint P
IGI
SceS000000566
IMP
SceS000000566
IPI
SceS000000566
GO:0000723 telomere maintenance P
IMP
SceS000000566
GO:0006260 DNA replication P
IMP
SceS000000566
RCA
SceS000000566
GO:0006281 DNA repair P
IGI
SceS000000566
IMP
SceS000000566
RCA
SceS000000566
GO:0006348 chromatin silencing at telomere P
IGI
SceS000000566
IMP
SceS000000566
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000566
GO:0007064 mitotic sister chromatid cohesion P
IGI
SceS000000566
IMP
SceS000000566
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000000566
GO:0016458 gene silencing P
RCA
SceS000000566
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000000566
IMP
SceS000000566
GO:0031573 intra-S DNA damage checkpoint P
IMP
SceS000000566
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000000566
GO:0043570 maintenance of DNA repeat elements P
IMP
SceS000000566
GO:0048478 replication fork protection P
IGI
SceS000000566
IMP
SceS000000566
IPI
SceS000000566
GO:0051276 chromosome organization P
RCA
SceS000000566

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13181

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3939 AFR745W
Candida glabrata (Cgl) cgl218 CAGL0B00330g
Cryptococcus neoformans (Cne) cne5212 179.m00058
Debaryomyces hansenii (Dha) dha3893 DEHA0E14729g
Kluyveromyces lactis (Kla) kla1214 KLLA0C00484g
Neurospora crassa (Ncr) ncr4197 NCU04321.2
Saccharomyces cerevisiae (Sce) sce642 YCL061C
(S000000566)
Schizosaccharomyces pombe (Spo) spo6 SPAC694.06c Q9P7T4
Yarrowia lipolytica (Yli) yli4919 YALI0E25762g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000000566
GO:0000790 nuclear chromatin C
IDA
SpoSPAC694.06c
GO:0005634 nucleus C
IDA
SceS000000566
SpoSPAC694.06c
TAS
SpoSPAC694.06c
GO:0031298 replication fork protection complex C
IDA
SceS000000566
GO:0043234 protein complex C
NAS
SpoSPAC694.06c
GO:0043596 nuclear replication fork C
IDA
SceS000000566
TAS
SpoSPAC694.06c
GO:0000403 Y-form DNA binding F
IDA
SpoSPAC694.06c
GO:0003674 molecular_function F
ND
SceS000000566
GO:0003677 DNA binding F
IDA
SpoSPAC694.06c
GO:0005515 protein binding F
IPI
SpoSPAC694.06c
GO:0043539 protein serine/threonine kinase activator
activity		 F
TAS
SpoSPAC694.06c
GO:0000076 DNA replication checkpoint P
IGI
SceS000000566
IMP
SceS000000566
SpoSPAC694.06c
IPI
SceS000000566
GO:0000723 telomere maintenance P
IMP
SceS000000566
GO:0006260 DNA replication P
IMP
SceS000000566
RCA
SceS000000566
GO:0006281 DNA repair P
IGI
SceS000000566
IMP
SceS000000566
RCA
SceS000000566
GO:0006348 chromatin silencing at telomere P
IGI
SceS000000566
IMP
SceS000000566
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000566
GO:0007064 mitotic sister chromatid cohesion P
IGI
SceS000000566
IMP
SceS000000566
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC694.06c
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000000566
GO:0016458 gene silencing P
RCA
SceS000000566
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000000566
IMP
SceS000000566
GO:0031573 intra-S DNA damage checkpoint P
IDA
SpoSPAC694.06c
IMP
SceS000000566
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000000566
GO:0042327 positive regulation of phosphorylation P
TAS
SpoSPAC694.06c
GO:0043570 maintenance of DNA repeat elements P
IMP
SceS000000566
GO:0048478 replication fork protection P
IGI
SceS000000566
IMP
SceS000000566
IPI
SceS000000566
GO:0051276 chromosome organization P
RCA
SceS000000566

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC694.06c
(Q9P7T4)		 YCL061C
(S000000566)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IPI
SceS000000566
GO:0000790 nuclear chromatin C
IDA
SpoSPAC694.06c
GO:0005634 nucleus C
IDA
SceS000000566
SpoSPAC694.06c
TAS
SpoSPAC694.06c
GO:0031298 replication fork protection complex C
IDA
SceS000000566
GO:0043234 protein complex C
NAS
SpoSPAC694.06c
GO:0043596 nuclear replication fork C
IDA
SceS000000566
TAS
SpoSPAC694.06c
GO:0000403 Y-form DNA binding F
IDA
SpoSPAC694.06c
GO:0003674 molecular_function F
ND
SceS000000566
GO:0003677 DNA binding F
IDA
SpoSPAC694.06c
GO:0005515 protein binding F
IPI
SpoSPAC694.06c
GO:0043539 protein serine/threonine kinase activator
activity		 F
TAS
SpoSPAC694.06c
GO:0000076 DNA replication checkpoint P
IGI
SceS000000566
IMP
SceS000000566
SpoSPAC694.06c
IPI
SceS000000566
GO:0000723 telomere maintenance P
IMP
SceS000000566
GO:0006260 DNA replication P
IMP
SceS000000566
RCA
SceS000000566
GO:0006281 DNA repair P
IGI
SceS000000566
IMP
SceS000000566
RCA
SceS000000566
GO:0006348 chromatin silencing at telomere P
IGI
SceS000000566
IMP
SceS000000566
GO:0006974 response to DNA damage stimulus P
RCA
SceS000000566
GO:0007064 mitotic sister chromatid cohesion P
IGI
SceS000000566
IMP
SceS000000566
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC694.06c
GO:0009890 negative regulation of biosynthetic
process		 P
RCA
SceS000000566
GO:0016458 gene silencing P
RCA
SceS000000566
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000000566
IMP
SceS000000566
GO:0031573 intra-S DNA damage checkpoint P
IDA
SpoSPAC694.06c
IMP
SceS000000566
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000000566
GO:0042327 positive regulation of phosphorylation P
TAS
SpoSPAC694.06c
GO:0043570 maintenance of DNA repeat elements P
IMP
SceS000000566
GO:0048478 replication fork protection P
IGI
SceS000000566
IMP
SceS000000566
IPI
SceS000000566
GO:0051276 chromosome organization P
RCA
SceS000000566

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

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