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Search term: YCL064C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CHA1
SGD link S000000569
Alternative ID YCL064C
Description Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
Synonyms YCL064C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1250 ACDHYP-

KOGs classification KOGs description
METABOLISM Threonine/serine dehydratases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g10050 GI:15232827
Caenorhabditis elegans (Cel) CE02261 GI:17534813
Caenorhabditis elegans (Cel) CE26153
(WBGene00021787)		 GI:17537387 Q95XY8
Drosophila melanogaster (Dme) 7299166 GI:7299166 Q7KST5
Homo sapiens (Hsa) Hs5803161 GI:5803161
Homo sapiens (Hsa) Hs19923959
(SDSL)		 GI:19923959 Q96GA7
Saccharomyces cerevisiae (Sce) YCL064c
(S000000569)		 GI:10383753
Saccharomyces cerevisiae (Sce) YER086w
(S000000888)		 GI:6320930 P00927
Schizosaccharomyces pombe (Spo) SPBC1677.03c GI:19113433 O94634
Arabidopsis thaliana (Ath) At3g10050 GI:15232827
Caenorhabditis elegans (Cel) CE02261 GI:17534813
Caenorhabditis elegans (Cel) CE26153
(WBGene00021787)		 GI:17537387 Q95XY8
Drosophila melanogaster (Dme) 7299166 GI:7299166 Q7KST5
Homo sapiens (Hsa) Hs5803161 GI:5803161
Homo sapiens (Hsa) Hs19923959
(SDSL)		 GI:19923959 Q96GA7
Saccharomyces cerevisiae (Sce) YCL064c
(S000000569)		 GI:10383753
Saccharomyces cerevisiae (Sce) YER086w
(S000000888)		 GI:6320930 P00927
Schizosaccharomyces pombe (Spo) SPBC1677.03c GI:19113433 O94634


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaSDSL
GO:0005737 cytoplasm C
IDA
SpoSPBC1677.03c
GO:0005739 mitochondrion C
IDA
SceS000000888
S000000569
ISS
SpoSPBC1677.03c
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000569
GO:0003674 molecular_function F
ND
HsaSDSL
GO:0003941 L-serine ammonia-lyase activity F
IDA
SceS000000569
GO:0004794 L-threonine ammonia-lyase activity F
IDA
SceS000000569
IMP
AthAt3g10050
SceS000000888
ISS
AthAt3g10050
SpoSPBC1677.03c
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00021787
GO:0006082 organic acid metabolic process P
RCA
SceS000000888
GO:0006414 translational elongation P
RCA
SceS000000569
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000000888
GO:0006565 L-serine catabolic process P
IGI
SceS000000569
GO:0006566 threonine metabolic process P
ISS
AthAt3g10050
GO:0006567 threonine catabolic process P
IGI
SceS000000888
S000000569
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000000888
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000000888
GO:0009097 isoleucine biosynthetic process P
IMP
SceS000000888
ISS
SpoSPBC1677.03c
TAS
AthAt3g10050
GO:0022610 biological adhesion P
ND
HsaSDSL
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021787
GO:0040011 locomotion P
IMP
CelWBGene00021787
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00021787

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
44224

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SDSL GI:19923959 Q96GA7
Pan troglodytes (Ptr) SDSL GI:114647126
Canis familiaris (Cfa) SDSL GI:73995256
Mus musculus (Mmu) Sdsl
(MGI:2182607)		 GI:20589949 Q8R238
Rattus norvegicus (Rno) Sdsl GI:109496023
Gallus gallus (Gga) SDSL GI:118098895
Saccharomyces cerevisiae (Sce) CHA1
(S000000569)		 GI:63535562
Kluyveromyces lactis (Kla) KLLA0C00440g GI:50304517
Magnaporthe grisea (Mgr) MGG_14171 GI:145602791


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaSDSL
MmuMGI:2182607
GO:0005739 mitochondrion C
IDA
MmuMGI:2182607
SceS000000569
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000569
GO:0003674 molecular_function F
ND
HsaSDSL
MmuMGI:2182607
GO:0003941 L-serine ammonia-lyase activity F
IDA
SceS000000569
GO:0004794 L-threonine ammonia-lyase activity F
IDA
SceS000000569
GO:0006414 translational elongation P
RCA
SceS000000569
GO:0006565 L-serine catabolic process P
IGI
SceS000000569
GO:0006567 threonine catabolic process P
IGI
SceS000000569
GO:0008150 biological_process P
ND
MmuMGI:2182607
GO:0022610 biological adhesion P
ND
HsaSDSL

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2737

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3941 AFR747W
Candida glabrata (Cgl) cgl216 CAGL0B00286g
Cryptococcus neoformans (Cne) cne3388 167.m05918
Cryptococcus neoformans (Cne) cne3443 176.m02473
Dictyostelium discoideum (Ddi) ddi11798 DDB0230212
Debaryomyces hansenii (Dha) dha110 DEHA0A02497g
Debaryomyces hansenii (Dha) dha2405 DEHA0D02431g
Danio rerio (Dre) dre959 ENSDARP00000024133
Takifugu rubripes (Fru) fru22575 SINFRUP00000144526
Takifugu rubripes (Fru) fru22576 SINFRUP00000144528
Takifugu rubripes (Fru) fru29598 SINFRUP00000160178
Gallus gallus (Gga) gga7663 ENSGALP00000013521
Gallus gallus (Gga) gga7661 ENSGALP00000013522
(SDSL)
Gallus gallus (Gga) gga7662 ENSGALP00000013523
Homo sapiens (Hsa) hsa8239 ENSP00000257549
(SDS)		 P20132
Homo sapiens (Hsa) hsa8240 ENSP00000341117
(SDSL)		 Q96GA7
Kluyveromyces lactis (Kla) kla1212 KLLA0C00440g
Kluyveromyces lactis (Kla) kla3028 KLLA0E01804g
Mus musculus (Mmu) mmu20814 ENSMUSP00000031594
(MGI:2182607)		 Q8R238
Mus musculus (Mmu) mmu20813 ENSMUSP00000058198
(MGI:2182607)		 Q8R238
Mus musculus (Mmu) mmu20815 ENSMUSP00000064849
(MGI:98270)		 Q8VBT2
Neurospora crassa (Ncr) ncr3651 NCU03761.2
Rattus norvegicus (Rno) rno8665 ENSRNOP00000001875
(RGD:67376)		 P09367-2
Rattus norvegicus (Rno) rno8664 ENSRNOP00000001876
(RGD:67376)		 P09367-1
Rattus norvegicus (Rno) rno8666 ENSRNOP00000001882
(RGD:1309192)
Saccharomyces cerevisiae (Sce) sce644 YCL064C
(S000000569)
Yarrowia lipolytica (Yli) yli1419 YALI0B16214g
Yarrowia lipolytica (Yli) yli4288 YALI0E10307g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2182607
MGI:98270
GO:0005739 mitochondrion C
IDA
MmuMGI:2182607
SceS000000569
GO:0042645 mitochondrial nucleoid C
IDA
SceS000000569
GO:0003674 molecular_function F
ND
MmuMGI:2182607
GO:0003941 L-serine ammonia-lyase activity F
IDA
SceS000000569
GO:0004794 L-threonine ammonia-lyase activity F
IDA
SceS000000569
GO:0046983 protein dimerization activity F
ISO
MmuMGI:98270
GO:0006414 translational elongation P
RCA
SceS000000569
GO:0006565 L-serine catabolic process P
IGI
SceS000000569
GO:0006567 threonine catabolic process P
IGI
SceS000000569
GO:0008150 biological_process P
ND
MmuMGI:2182607
MGI:98270

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