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Search term: YCR067C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SED4
SGD link S000000663
Alternative ID YCR067C
Description Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p
Synonyms YCR067C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40162

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SED4
(S000000663)		 GI:6319912 P25365
Kluyveromyces lactis (Kla) KLLA0C08723g GI:50305259
Eremothecium gossypii (Ego) AGOS_AAR048W GI:45184871


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IDA
SceS000000663
GO:0003674 molecular_function F
ND
SceS000000663
GO:0034260 negative regulation of GTPase activity P
IDA
SceS000000663
GO:0090114 COPII-coated vesicle budding P
IGI
SceS000000663

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_10410

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago234 AAR048W
Candida glabrata (Cgl) cgl3142 CAGL0J03564g
Candida glabrata (Cgl) cgl5124 CAGL0M10703g
Cryptococcus neoformans (Cne) cne3615 176.m02349
Debaryomyces hansenii (Dha) dha4978 DEHA0F13409g
Kluyveromyces lactis (Kla) kla1588 KLLA0C08723g
Neurospora crassa (Ncr) ncr365 NCU00379.2
Saccharomyces cerevisiae (Sce) sce724 YCR067C
(S000000663)
Saccharomyces cerevisiae (Sce) sce5493 YNR026C
(S000005309)
Schizosaccharomyces pombe (Spo) spo1843 SPBC3H7.01 Q10659
Yarrowia lipolytica (Yli) yli287 YALI0A08646g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000299 integral to membrane of membrane
fraction		 C
IDA
SceS000005309
GO:0005737 cytoplasm C
IDA
SpoSPBC3H7.01
GO:0005783 endoplasmic reticulum C
IDA
SceS000005309
SpoSPBC3H7.01
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPBC3H7.01
GO:0005794 Golgi apparatus C
IDA
SceS000005309
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IDA
SceS000000663
GO:0043234 protein complex C
NAS
SpoSPBC3H7.01
GO:0003674 molecular_function F
ND
SceS000000663
GO:0005085 guanyl-nucleotide exchange factor
activity		 F
ISS
SpoSPBC3H7.01
GO:0005090 Sar guanyl-nucleotide exchange factor
activity		 F
IDA
SceS000005309
IMP
SceS000005309
GO:0003400 regulation of COPII vesicle coating P
IDA
SceS000005309
GO:0006888 ER to Golgi vesicle-mediated transport P
ISS
SpoSPBC3H7.01
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005309
GO:0031321 ascospore-type prospore formation P
IMP
SpoSPBC3H7.01
GO:0031322 ascospore-type prospore-specific spindle pole body
modification		 P
IMP
SpoSPBC3H7.01
GO:0032120 ascospore-type prospore membrane
assembly		 P
IMP
SpoSPBC3H7.01
GO:0034260 negative regulation of GTPase activity P
IDA
SceS000000663
GO:0090114 COPII-coated vesicle budding P
IGI
SceS000000663

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