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Search term: YCR068W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ATG15
SGD link S000000664
Alternative ID YCR068W
Description Lipase required for intravacuolar lysis of autophagic bodies and Cvt bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
Synonyms YCR068W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4540 ----YPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGMETABOLISM Putative lipase essential for disintegration of autophagic bodies inside the vacuole

Species KOG link NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YCR068w
(S000000664)		 GI:10383802 P25641
Schizosaccharomyces pombe (Spo) SPAC23C4.16c GI:19114100 O13934
Encephalitozoon cuniculi (Ecu) ECU04g0660 GI:19074143 Q8SVV1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005775 vacuolar lumen C
IDA
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C4.16c
GO:0016021 integral to membrane C
IDA
SceS000000664
IPI
SceS000000664
ISS
SceS000000664
GO:0016298 lipase activity F
ISM
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0006624 vacuolar protein processing P
IDA
SceS000000664
IMP
SceS000000664
GO:0006914 autophagy P
IDA
SceS000000664
IMP
SceS000000664
SpoSPAC23C4.16c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPAC23C4.16c
GO:0016236 macroautophagy P
IC
SpoSPAC23C4.16c
GO:0030397 membrane disassembly P
IDA
SceS000000664
IMP
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0030437 ascospore formation P
IMP
SpoSPAC23C4.16c
GO:0034496 multivesicular body membrane disassembly P
IMP
SceS000000664
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000000664

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31489

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) atg15
(SPAC23C4.16c)		 GI:19114100 O13934
Saccharomyces cerevisiae (Sce) ATG15
(S000000664)		 GI:10383802 P25641
Kluyveromyces lactis (Kla) KLLA0C08679g GI:50305255
Eremothecium gossypii (Ego) AGOS_AAR046C GI:45184869


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005775 vacuolar lumen C
IDA
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C4.16c
GO:0016021 integral to membrane C
IDA
SceS000000664
IPI
SceS000000664
ISS
SceS000000664
GO:0016298 lipase activity F
ISM
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0006624 vacuolar protein processing P
IDA
SceS000000664
IMP
SceS000000664
GO:0006914 autophagy P
IDA
SceS000000664
IMP
SceS000000664
SpoSPAC23C4.16c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPAC23C4.16c
GO:0016236 macroautophagy P
IC
SpoSPAC23C4.16c
GO:0030397 membrane disassembly P
IDA
SceS000000664
IMP
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0030437 ascospore formation P
IMP
SpoSPAC23C4.16c
GO:0034496 multivesicular body membrane disassembly P
IMP
SceS000000664
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000000664

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11647

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago232 AAR046C
Candida glabrata (Cgl) cgl3141 CAGL0J03542g
Cryptococcus neoformans (Cne) cne5257 179.m00106
Debaryomyces hansenii (Dha) dha4980 DEHA0F13453g
Encephalitozoon cuniculi (Ecu) ecu781 19074143
Kluyveromyces lactis (Kla) kla1586 KLLA0C08679g
Neurospora crassa (Ncr) ncr6255 NCU06436.2
Saccharomyces cerevisiae (Sce) sce725 YCR068W
(S000000664)
Schizosaccharomyces pombe (Spo) spo702 SPAC23C4.16c O13934
Yarrowia lipolytica (Yli) yli5611 YALI0F06358g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005775 vacuolar lumen C
IDA
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C4.16c
GO:0016021 integral to membrane C
IDA
SceS000000664
IPI
SceS000000664
ISS
SceS000000664
GO:0016298 lipase activity F
ISM
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0006624 vacuolar protein processing P
IDA
SceS000000664
IMP
SceS000000664
GO:0006914 autophagy P
IDA
SceS000000664
IMP
SceS000000664
SpoSPAC23C4.16c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPAC23C4.16c
GO:0016236 macroautophagy P
IC
SpoSPAC23C4.16c
GO:0030397 membrane disassembly P
IDA
SceS000000664
IMP
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0030437 ascospore formation P
IMP
SpoSPAC23C4.16c
GO:0034496 multivesicular body membrane disassembly P
IMP
SceS000000664
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000000664

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C4.16c
(O13934)		 YCR068W
(S000000664)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005775 vacuolar lumen C
IDA
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C4.16c
GO:0016021 integral to membrane C
IDA
SceS000000664
IPI
SceS000000664
ISS
SceS000000664
GO:0016298 lipase activity F
ISM
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0006624 vacuolar protein processing P
IDA
SceS000000664
IMP
SceS000000664
GO:0006914 autophagy P
IDA
SceS000000664
IMP
SceS000000664
SpoSPAC23C4.16c
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPAC23C4.16c
GO:0016236 macroautophagy P
IC
SpoSPAC23C4.16c
GO:0030397 membrane disassembly P
IDA
SceS000000664
IMP
SceS000000664
ISS
SpoSPAC23C4.16c
GO:0030437 ascospore formation P
IMP
SpoSPAC23C4.16c
GO:0034496 multivesicular body membrane disassembly P
IMP
SceS000000664
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000000664

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s.khadayate@ucl.ac.uk