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Search term: YCR069W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CPR4
SGD link S000000665
Alternative ID YCR069W
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
Synonyms YCR069W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0880 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Peptidyl-prolyl cis-trans isomerase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g62030 GI:15228674
Arabidopsis thaliana (Ath) At5g13120 GI:15240008
Caenorhabditis elegans (Cel) CE01301
(WBGene00000882)
GI:17552780 P52014
Caenorhabditis elegans (Cel) CE17730
(WBGene00000881)
GI:17506307 P52013
Drosophila melanogaster (Dme) 7291447
(FBgn0034753)
GI:20130249
Drosophila melanogaster (Dme) 7296144
(FBgn0002936)
GI:17136360 P15425
Homo sapiens (Hsa) Hs4505991
(PPIC)
GI:4505991 P45877
Homo sapiens (Hsa) Hs4758950
(PPIB)
GI:4758950 P23284
Saccharomyces cerevisiae (Sce) YCR069w
(S000000665)
GI:6319914 P25334
Saccharomyces cerevisiae (Sce) YDR304c
(S000002712)
GI:6320510 P35176
Saccharomyces cerevisiae (Sce) YHR057c
(S000001099)
GI:6321848 P23285
Saccharomyces cerevisiae (Sce) YNR028w
(S000005311)
GI:6324355 P53728
Schizosaccharomyces pombe (Spo) SPBP8B7.25 GI:19113324 O94273
Arabidopsis thaliana (Ath) At3g62030 GI:15228674
Arabidopsis thaliana (Ath) At5g13120 GI:15240008
Caenorhabditis elegans (Cel) CE01301
(WBGene00000882)
GI:17552780 P52014
Caenorhabditis elegans (Cel) CE17730
(WBGene00000881)
GI:17506307 P52013
Drosophila melanogaster (Dme) 7291447
(FBgn0034753)
GI:20130249
Drosophila melanogaster (Dme) 7296144
(FBgn0002936)
GI:17136360 P15425
Homo sapiens (Hsa) Hs4505991
(PPIC)
GI:4505991 P45877
Homo sapiens (Hsa) Hs4758950
(PPIB)
GI:4758950 P23284
Saccharomyces cerevisiae (Sce) YCR069w
(S000000665)
GI:6319914 P25334
Saccharomyces cerevisiae (Sce) YDR304c
(S000002712)
GI:6320510 P35176
Saccharomyces cerevisiae (Sce) YHR057c
(S000001099)
GI:6321848 P23285
Saccharomyces cerevisiae (Sce) YNR028w
(S000005311)
GI:6324355 P53728
Schizosaccharomyces pombe (Spo) SPBP8B7.25 GI:19113324 O94273


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000005311
GO:0005575 cellular_component C
ND
SceS000001099
GO:0005624 membrane fraction C
IDA
DmeFBgn0002936
GO:0005737 cytoplasm C
IDA
SceS000002712
GO:0005783 endoplasmic reticulum C
IDA
SceS000002712
SpoSPBP8B7.25
GO:0005788 endoplasmic reticulum lumen C
IDA
DmeFBgn0002936
ISS
SpoSPBP8B7.25
NAS
HsaPPIB
GO:0005794 Golgi apparatus C
IDA
SpoSPBP8B7.25
GO:0005811 lipid particle C
IDA
DmeFBgn0034753
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0034753
GO:0005887 integral to plasma membrane C
NAS
DmeFBgn0002936
GO:0009507 chloroplast C
IDA
AthAt3g62030
At5g13120
GO:0009533 chloroplast stromal thylakoid C
IDA
AthAt5g13120
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt3g62030
At5g13120
GO:0009543 chloroplast thylakoid lumen C
IDA
AthAt5g13120
GO:0009570 chloroplast stroma C
IDA
AthAt3g62030
GO:0009579 thylakoid C
IDA
AthAt3g62030
At5g13120
GO:0009941 chloroplast envelope C
IDA
AthAt3g62030
GO:0016020 membrane C
ISS
SceS000000665
GO:0016021 integral to membrane C
IDA
DmeFBgn0002936
GO:0016023 cytoplasmic membrane-bounded vesicle C
IDA
DmeFBgn0002936
GO:0022626 cytosolic ribosome C
IDA
AthAt3g62030
GO:0031977 thylakoid lumen C
IDA
AthAt5g13120
At3g62030
GO:0048046 apoplast C
IDA
AthAt3g62030
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
AthAt3g62030
SceS000001099
IMP
AthAt5g13120
ISS
AthAt5g13120
At3g62030
DmeFBgn0002936
FBgn0034753
SceS000005311
S000002712
S000000665
NAS
DmeFBgn0002936
HsaPPIB
TAS
DmeFBgn0002936
GO:0005515 protein binding F
IPI
HsaPPIB
GO:0016018 cyclosporin A binding F
IMP
DmeFBgn0002936
TAS
HsaPPIC
GO:0051082 unfolded protein binding F
TAS
HsaPPIB
PPIC
GO:0006457 protein folding P
ISS
AthAt3g62030
At5g13120
GO:0006458 'de novo' protein folding P
NAS
DmeFBgn0002936
TAS
DmeFBgn0002936
GO:0006810 transport P
TAS
DmeFBgn0002936
GO:0006979 response to oxidative stress P
IMP
AthAt3g62030
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000665
GO:0007165 signal transduction P
ISS
AthAt3g62030
TAS
HsaPPIC
GO:0007602 phototransduction P
IPI
DmeFBgn0002936
NAS
DmeFBgn0002936
TAS
DmeFBgn0002936
GO:0007603 phototransduction, visible light P
IMP
DmeFBgn0002936
GO:0008150 biological_process P
ND
SceS000001099
S000002712
S000005311
S000000665
GO:0009642 response to light intensity P
IMP
AthAt3g62030
GO:0009651 response to salt stress P
IMP
AthAt3g62030
GO:0009737 response to abscisic acid stimulus P
IEP
AthAt3g62030
GO:0010275 NAD(P)H dehydrogenase complex assembly P
IMP
AthAt5g13120
GO:0010555 response to mannitol stimulus P
IMP
AthAt3g62030
GO:0016063 rhodopsin biosynthetic process P
IMP
DmeFBgn0002936
NAS
DmeFBgn0002936
TAS
DmeFBgn0002936
GO:0019344 cysteine biosynthetic process P
IMP
AthAt3g62030
GO:0042742 defense response to bacterium P
IEP
AthAt3g62030
GO:0070059 apoptosis in response to endoplasmic reticulum
stress
P
IMP
DmeFBgn0002936

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56077

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CPR4
(S000000665)
GI:6319914 P25334
Kluyveromyces lactis (Kla) KLLA0C08635g GI:50305251
Eremothecium gossypii (Ego) AGOS_AAR045C GI:45184868


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016020 membrane C
ISS
SceS000000665
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
ISS
SceS000000665
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000665
GO:0008150 biological_process P
ND
SceS000000665

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31632

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago231 AAR045C
Candida glabrata (Cgl) cgl3140 CAGL0J03520g
Kluyveromyces lactis (Kla) kla1584 KLLA0C08635g
Saccharomyces cerevisiae (Sce) sce726 YCR069W
(S000000665)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016020 membrane C
ISS
SceS000000665
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
ISS
SceS000000665
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000665
GO:0008150 biological_process P
ND
SceS000000665

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GO info in one table:

s.khadayate@ucl.ac.uk