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Search term: YCR075C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERS1
SGD link S000000671
Alternative ID YCR075C
Description Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains
Synonyms YCR075C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3145 ACDHY--

KOGs classification KOGs description
METABOLISM Cystine transporter Cystinosin

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g40670 GI:15237468
Caenorhabditis elegans (Cel) CE28541
(WBGene00008052)		 GI:17532373 Q09500
Drosophila melanogaster (Dme) 7300949 GI:13124103
Homo sapiens (Hsa) Hs4826682 GI:4826682
Saccharomyces cerevisiae (Sce) YCR075c
(S000000671)		 GI:6319919 P17261


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000000671
GO:0005765 lysosomal membrane C
IDA
CelWBGene00008052
GO:0005768 endosome C
IDA
SceS000000671
GO:0005886 plasma membrane C
IDA
AthAt5g40670
GO:0016020 membrane C
ISS
AthAt5g40670
GO:0003674 molecular_function F
ND
AthAt5g40670
GO:0015184 L-cystine transmembrane transporter
activity		 F
IGI
SceS000000671
ISS
SceS000000671
GO:0006414 translational elongation P
RCA
SceS000000671
GO:0008150 biological_process P
ND
AthAt5g40670
GO:0009415 response to water P
RCA
SceS000000671
GO:0015811 L-cystine transport P
IGI
SceS000000671
ISS
SceS000000671
GO:0055085 transmembrane transport P
ISS
SceS000000671

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38539

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ERS1
(S000000671)		 GI:6319919 P17261
Kluyveromyces lactis (Kla) KLLA0F27445g GI:50312531
Eremothecium gossypii (Ego) AGOS_AER269C GI:45190872


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000000671
GO:0005768 endosome C
IDA
SceS000000671
GO:0015184 L-cystine transmembrane transporter
activity		 F
IGI
SceS000000671
ISS
SceS000000671
GO:0006414 translational elongation P
RCA
SceS000000671
GO:0009415 response to water P
RCA
SceS000000671
GO:0015811 L-cystine transport P
IGI
SceS000000671
ISS
SceS000000671
GO:0055085 transmembrane transport P
ISS
SceS000000671

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3789

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3733 ENSANGP00000018133
Anopheles gambiae (Aga) aga6629 ENSANGP00000020402
Ashbya gossypii (Ago) ago2771 AER269C
Arabidopsis thaliana (Ath) ath25843 At5g40670.1
Caenorhabditis elegans (Cel) cel3822 C41C4.7a
(CE28541;
WBGene00008052)
Caenorhabditis elegans (Cel) cel3823 C41C4.7b
(CE32325)
Candida glabrata (Cgl) cgl4961 CAGL0M06985g
Cryptococcus neoformans (Cne) cne1996 181.m07977
Dictyostelium discoideum (Ddi) ddi4368 DDB0205769
Debaryomyces hansenii (Dha) dha1873 DEHA0C10021g
Drosophila melanogaster (Dme) dme13953 CG17119-PA
(FBgn0039045)
Drosophila melanogaster (Dme) dme13954 CG17119-PB
(FBgn0039045)
Danio rerio (Dre) dre2312 ENSDARP00000024767
(zgc:110194)		 Q503T0
Takifugu rubripes (Fru) fru4055 SINFRUP00000143557
Gallus gallus (Gga) gga8955 ENSGALP00000007361
(CTNS)
Homo sapiens (Hsa) hsa12816 ENSP00000046640
(CTNS)		 O60931-1
Kluyveromyces lactis (Kla) kla5301 KLLA0F27445g
Mus musculus (Mmu) mmu4177 ENSMUSP00000006103
(MGI:1932872)		 P57757
Neurospora crassa (Ncr) ncr1212 NCU01250.2
Oryza sativa (Osa) osa54789 6085.m00029
Rattus norvegicus (Rno) rno5491 ENSRNOP00000031580
(RGD:1308466)
Saccharomyces cerevisiae (Sce) sce731 YCR075C
(S000000671)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000000671
GO:0005764 lysosome C
IDA
MmuMGI:1932872
GO:0005765 lysosomal membrane C
IDA
CelWBGene00008052
NAS
DmeFBgn0039045
GO:0005768 endosome C
IDA
SceS000000671
GO:0005886 plasma membrane C
IDA
AthAt5g40670
GO:0016020 membrane C
ISS
AthAt5g40670
GO:0003674 molecular_function F
ND
AthAt5g40670
GO:0015171 amino acid transmembrane transporter
activity		 F
ISS
DmeFBgn0039045
GO:0015184 L-cystine transmembrane transporter
activity		 F
IDA
MmuMGI:1932872
IGI
SceS000000671
IMP
MmuMGI:1932872
ISS
SceS000000671
NAS
DmeFBgn0039045
GO:0003333 amino acid transmembrane transport P
IDA
MmuMGI:1932872
IMP
MmuMGI:1932872
ISS
DmeFBgn0039045
GO:0006414 translational elongation P
RCA
SceS000000671
GO:0008150 biological_process P
ND
AthAt5g40670
GO:0009415 response to water P
RCA
SceS000000671
GO:0015811 L-cystine transport P
IDA
MmuMGI:1932872
IGI
SceS000000671
IMP
MmuMGI:1932872
ISS
SceS000000671
NAS
DmeFBgn0039045
GO:0055085 transmembrane transport P
ISS
SceS000000671

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