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Search term: YCR081W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SRB8
SGD link S000000677
Alternative ID YCR081W
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression
Synonyms YCR081W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4522 A---YP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA polymerase II transcription mediator

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g00450 GI:15236823
Saccharomyces cerevisiae (Sce) YCR081w
(S000000677)
GI:6319923 P25648
Schizosaccharomyces pombe (Spo) SPAC688.08 GI:19114978 Q9P6L8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005667 transcription factor complex C
TAS
SceS000000677
GO:0016592 mediator complex C
IDA
SpoSPAC688.08
RCA
SceS000000677
GO:0003674 molecular_function F
ND
AthAt4g00450
GO:0016455 RNA polymerase II transcription mediator
activity
F
ISS
SpoSPAC688.08
TAS
SceS000000677
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
TAS
SceS000000677
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter
P
IEP
SpoSPAC688.08
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IEP
SpoSPAC688.08
GO:0040034 regulation of development, heterochronic P
IMP
AthAt4g00450
GO:0048573 photoperiodism, flowering P
NAS
AthAt4g00450
GO:0090213 regulation of radial pattern formation P
IMP
AthAt4g00450

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38542

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SRB8
(S000000677)
GI:6319923 P25648
Kluyveromyces lactis (Kla) KLLA0F06919g GI:50310745
Eremothecium gossypii (Ego) AGOS_AGL226C GI:45200871


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005667 transcription factor complex C
TAS
SceS000000677
GO:0016592 mediator complex C
RCA
SceS000000677
GO:0016455 RNA polymerase II transcription mediator
activity
F
TAS
SceS000000677
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
TAS
SceS000000677

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11600

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4086 AGL226C
Candida glabrata (Cgl) cgl968 CAGL0E00627g
Cryptococcus neoformans (Cne) cne3891 185.m02737
Debaryomyces hansenii (Dha) dha1868 DEHA0C09911g
Kluyveromyces lactis (Kla) kla4394 KLLA0F06919g
Neurospora crassa (Ncr) ncr935 NCU00962.2
Oryza sativa (Osa) osa30331 4308.m00104
Saccharomyces cerevisiae (Sce) sce737 YCR081W
(S000000677)
Schizosaccharomyces pombe (Spo) spo2678 SPAC688.08 Q9P6L8
Yarrowia lipolytica (Yli) yli5819 YALI0F11341g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005667 transcription factor complex C
TAS
SceS000000677
GO:0016592 mediator complex C
IDA
SpoSPAC688.08
RCA
SceS000000677
GO:0016455 RNA polymerase II transcription mediator
activity
F
ISS
SpoSPAC688.08
TAS
SceS000000677
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
TAS
SceS000000677
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter
P
IEP
SpoSPAC688.08
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IEP
SpoSPAC688.08

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC688.08
(Q9P6L8)
YCR081W
(S000000677)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005667 transcription factor complex C
TAS
SceS000000677
GO:0016592 mediator complex C
IDA
SpoSPAC688.08
RCA
SceS000000677
GO:0016455 RNA polymerase II transcription mediator
activity
F
ISS
SpoSPAC688.08
TAS
SceS000000677
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
TAS
SceS000000677
GO:0010553 negative regulation of gene-specific transcription
from RNA polymerase II promoter
P
IEP
SpoSPAC688.08
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IEP
SpoSPAC688.08

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