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Search term: YCR094W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC50
SGD link S000000690
Alternative ID YCR094W
Description Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p
Synonyms YCR094W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2952 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALING Cell cycle control protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g16360 GI:15219220
Arabidopsis thaliana (Ath) At1g54320 GI:18404877
Arabidopsis thaliana (Ath) At1g79450 GI:18412377
Arabidopsis thaliana (Ath) At3g12740 GI:18399730
Arabidopsis thaliana (Ath) At5g46150 GI:9757735
Caenorhabditis elegans (Cel) CE03241
(WBGene00008969)		 GI:17539930 Q19635
Caenorhabditis elegans (Cel) CE03782 GI:17570229
Caenorhabditis elegans (Cel) CE07425
(WBGene00019946)		 GI:17541828
Drosophila melanogaster (Dme) 7293231 GI:7293231
Homo sapiens (Hsa) Hs8922720
(TMEM30A)		 GI:8922720 Q9NV96
Homo sapiens (Hsa) Hs18597131 GI:18597131
Homo sapiens (Hsa) Hs22042456 GI:22042456
Saccharomyces cerevisiae (Sce) YCR094w
(S000000690)		 GI:6319937 P25656
Saccharomyces cerevisiae (Sce) YNL323w
(S000005267)		 GI:6324006 P42838
Saccharomyces cerevisiae (Sce) YNR048w GI:6324376 P53740
Schizosaccharomyces pombe (Spo) SPBC11B10.07c GI:19112419 Q96WW4
Schizosaccharomyces pombe (Spo) SPBC1773.11c GI:19111918 Q1MTQ5
Encephalitozoon cuniculi (Ecu) ECU06g1450 GI:19074396 Q8SRN1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000299 integral to membrane of membrane
fraction		 C
IDA
SceS000000690
GO:0005737 cytoplasm C
IDA
SceS000005267
GO:0005770 late endosome C
IDA
SceS000000690
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005783 endoplasmic reticulum C
IDA
SceS000005267
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005794 Golgi apparatus C
IDA
AthAt3g12740
GO:0005802 trans-Golgi network C
IDA
SceS000000690
GO:0005886 plasma membrane C
IDA
AthAt1g79450
SceS000005267
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0009543 chloroplast thylakoid lumen C
ISS
AthAt1g79450
GO:0016020 membrane C
ISS
AthAt3g12740
At5g46150
At1g16360
At1g79450
At1g54320
GO:0016021 integral to membrane C
ISS
SceS000005267
YNR048w
SpoSPBC11B10.07c
SPBC1773.11c
GO:0003674 molecular_function F
ND
AthAt5g46150
SpoSPBC1773.11c
SPBC11B10.07c
GO:0004012 phospholipid-translocating ATPase
activity		 F
IPI
SceS000005267
S000000690
ISS
SceYNR048w
GO:0000003 reproduction P
IMP
CelWBGene00019946
GO:0006886 intracellular protein transport P
IMP
SceS000000690
GO:0006897 endocytosis P
IGI
SceS000000690
GO:0007166 cell surface receptor linked signaling
pathway		 P
IMP
SceS000005267
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0008150 biological_process P
ND
AthAt1g54320
At1g79450
At5g46150
At1g16360
GO:0010570 regulation of filamentous growth P
IMP
SpoSPBC11B10.07c
GO:0015914 phospholipid transport P
IDA
AthAt3g12740
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019946
GO:0042493 response to drug P
IGI
SceYNR048w
IMP
SceYNR048w
GO:0045332 phospholipid translocation P
IGI
SceS000000690
IMP
SceS000005267
GO:0051666 actin cortical patch localization P
IGI
SceS000000690

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
90919

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TMEM30B GI:63003930
Mus musculus (Mmu) Tmem30b
(MGI:2442082)		 GI:30520139 Q0VEI2
Rattus norvegicus (Rno) Tmem30b GI:27665752
Anopheles gambiae (Aga) AgaP_AGAP009984 GI:119114214
Schizosaccharomyces pombe (Spo) SPBC11B10.07c GI:19112419 Q96WW4
Saccharomyces cerevisiae (Sce) CDC50
(S000000690)		 GI:6319937 P25656
Kluyveromyces lactis (Kla) KLLA0C18634g GI:50306137
Eremothecium gossypii (Ego) AGOS_ADR170C GI:45188044
Oryza sativa (Osa) Os03g0120100 GI:115450369
Oryza sativa (Osa) Os05g0529900 GI:115465051


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000299 integral to membrane of membrane
fraction		 C
IDA
SceS000000690
GO:0005575 cellular_component C
ND
MmuMGI:2442082
GO:0005770 late endosome C
IDA
SceS000000690
ISS
SpoSPBC11B10.07c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC11B10.07c
GO:0005802 trans-Golgi network C
IDA
SceS000000690
GO:0005886 plasma membrane C
ISS
SpoSPBC11B10.07c
GO:0016021 integral to membrane C
ISS
SpoSPBC11B10.07c
GO:0003674 molecular_function F
ND
MmuMGI:2442082
SpoSPBC11B10.07c
GO:0004012 phospholipid-translocating ATPase
activity		 F
IPI
SceS000000690
GO:0006886 intracellular protein transport P
IMP
SceS000000690
GO:0006897 endocytosis P
IGI
SceS000000690
GO:0007166 cell surface receptor linked signaling
pathway		 P
ISS
SpoSPBC11B10.07c
GO:0008150 biological_process P
ND
MmuMGI:2442082
GO:0010570 regulation of filamentous growth P
IMP
SpoSPBC11B10.07c
GO:0045332 phospholipid translocation P
IGI
SceS000000690
GO:0051666 actin cortical patch localization P
IGI
SceS000000690

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_486

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15356 ENSANGP00000011914
Anopheles gambiae (Aga) aga12277 ENSANGP00000025967
Ashbya gossypii (Ago) ago1549 ADL192W
Ashbya gossypii (Ago) ago1912 ADR170C
Arabidopsis thaliana (Ath) ath1746 At1g16360.1
Arabidopsis thaliana (Ath) ath4745 At1g54320.1
Arabidopsis thaliana (Ath) ath7305 At1g79450.1
Arabidopsis thaliana (Ath) ath7306 At1g79450.2
Arabidopsis thaliana (Ath) ath13418 At3g12740.1
Caenorhabditis elegans (Cel) cel13587 R08C7.2a
(CE07425;
WBGene00019946)
Candida glabrata (Cgl) cgl568 CAGL0C03487g
Candida glabrata (Cgl) cgl766 CAGL0D02442g
Candida glabrata (Cgl) cgl959 CAGL0E00429g
Cryptococcus neoformans (Cne) cne2810 183.m01749
Cryptococcus neoformans (Cne) cne2811 183.m01830
Dictyostelium discoideum (Ddi) ddi2450 DDB0217816
Debaryomyces hansenii (Dha) dha1689 DEHA0C05808g
Debaryomyces hansenii (Dha) dha3334 DEHA0E02090g
Drosophila melanogaster (Dme) dme18189 CG9947-PA
(FBgn0030752)
Danio rerio (Dre) dre8434 ENSDARP00000039575
Danio rerio (Dre) dre12087 ENSDARP00000041021
Danio rerio (Dre) dre8435 ENSDARP00000046342
(zgc:91908)		 Q6GMG4
Encephalitozoon cuniculi (Ecu) ecu1623 19074396
Takifugu rubripes (Fru) fru3787 SINFRUP00000134463
Takifugu rubripes (Fru) fru20471 SINFRUP00000139642
Takifugu rubripes (Fru) fru3789 SINFRUP00000169990
Takifugu rubripes (Fru) fru20472 SINFRUP00000173732
Takifugu rubripes (Fru) fru3788 SINFRUP00000175480
Takifugu rubripes (Fru) fru20473 SINFRUP00000176705
Gallus gallus (Gga) gga15776 ENSGALP00000025582
(RCJMB04_32j24)		 Q5F362
Gallus gallus (Gga) gga15777 ENSGALP00000025583
Homo sapiens (Hsa) hsa27414 ENSP00000230461
(TMEM30A)		 Q9NV96-2
Homo sapiens (Hsa) hsa27413 ENSP00000323733
Homo sapiens (Hsa) hsa9634 ENSP00000347930
(TMEM30B)		 Q3MIR4
Kluyveromyces lactis (Kla) kla2029 KLLA0C18634g
Kluyveromyces lactis (Kla) kla3045 KLLA0E02178g
Mus musculus (Mmu) mmu27996 ENSMUSP00000034878
(MGI:106402)		 Q8VEK0
Mus musculus (Mmu) mmu5847 ENSMUSP00000037476
(MGI:2442082)		 Q8BHG3
Neurospora crassa (Ncr) ncr1129 NCU01165.2
Oryza sativa (Osa) osa2544 1952.m00127
Oryza sativa (Osa) osa55527 6161.m00215
Oryza sativa (Osa) osa69936 6975.m00111
Oryza sativa (Osa) osa79664 7449.m00102
Plasmodium falciparum (Pfa) pfa2408 PF07_0078
Rattus norvegicus (Rno) rno25266 ENSRNOP00000010923
(RGD:1308732)
Rattus norvegicus (Rno) rno28985 ENSRNOP00000015299
(RGD:1303315)		 Q6AY41
Rattus norvegicus (Rno) rno28984 ENSRNOP00000044430
(RGD:1303315)
Saccharomyces cerevisiae (Sce) sce751 YCR094W
(S000000690)
Saccharomyces cerevisiae (Sce) sce5447 YNL323W
(S000005267)
Saccharomyces cerevisiae (Sce) sce5517 YNR048W
Schizosaccharomyces pombe (Spo) spo759 SPBC11B10.07c Q96WW4
Schizosaccharomyces pombe (Spo) spo2058 SPBC1773.11c Q1MTQ5
Yarrowia lipolytica (Yli) yli5439 YALI0F02475g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000299 integral to membrane of membrane
fraction		 C
IDA
SceS000000690
GO:0005575 cellular_component C
ND
MmuMGI:2442082
MGI:106402
GO:0005737 cytoplasm C
IDA
SceS000005267
GO:0005770 late endosome C
IDA
SceS000000690
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005783 endoplasmic reticulum C
IDA
SceS000005267
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005794 Golgi apparatus C
IDA
AthAt3g12740
GO:0005802 trans-Golgi network C
IDA
SceS000000690
GO:0005886 plasma membrane C
IDA
AthAt1g79450
SceS000005267
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0009543 chloroplast thylakoid lumen C
ISS
AthAt1g79450
GO:0016020 membrane C
ISS
AthAt3g12740
At1g16360
At1g79450
At1g54320
GO:0016021 integral to membrane C
ISS
SceS000005267
YNR048w
SpoSPBC11B10.07c
SPBC1773.11c
GO:0003674 molecular_function F
ND
MmuMGI:2442082
MGI:106402
SpoSPBC1773.11c
SPBC11B10.07c
GO:0004012 phospholipid-translocating ATPase
activity		 F
IPI
SceS000005267
S000000690
ISS
SceYNR048w
GO:0000003 reproduction P
IMP
CelWBGene00019946
GO:0006886 intracellular protein transport P
IMP
SceS000000690
GO:0006897 endocytosis P
IGI
SceS000000690
GO:0007166 cell surface receptor linked signaling
pathway		 P
IMP
SceS000005267
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0008150 biological_process P
ND
AthAt1g54320
At1g79450
At1g16360
MmuMGI:2442082
MGI:106402
GO:0010570 regulation of filamentous growth P
IMP
SpoSPBC11B10.07c
GO:0015914 phospholipid transport P
IDA
AthAt3g12740
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019946
GO:0042493 response to drug P
IGI
SceYNR048w
IMP
SceYNR048w
GO:0045332 phospholipid translocation P
IGI
SceS000000690
IMP
SceS000005267
GO:0051666 actin cortical patch localization P
IGI
SceS000000690

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1773.11c
(Q1MTQ5)		 YCR094W
(S000000690)
SPBC11B10.07c
(Q96WW4)		 YCR094W
(S000000690)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000299 integral to membrane of membrane
fraction		 C
IDA
SceS000000690
GO:0005770 late endosome C
IDA
SceS000000690
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC11B10.07c
SPBC1773.11c
GO:0005802 trans-Golgi network C
IDA
SceS000000690
GO:0005886 plasma membrane C
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0016021 integral to membrane C
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0003674 molecular_function F
ND
SpoSPBC1773.11c
SPBC11B10.07c
GO:0004012 phospholipid-translocating ATPase
activity		 F
IPI
SceS000000690
GO:0006886 intracellular protein transport P
IMP
SceS000000690
GO:0006897 endocytosis P
IGI
SceS000000690
GO:0007166 cell surface receptor linked signaling
pathway		 P
ISS
SpoSPBC11B10.07c
SPBC1773.11c
GO:0010570 regulation of filamentous growth P
IMP
SpoSPBC11B10.07c
GO:0045332 phospholipid translocation P
IGI
SceS000000690
GO:0051666 actin cortical patch localization P
IGI
SceS000000690

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