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Search term: YDL013W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SLX5
SGD link S000002171
Alternative ID YDL013W
Description Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex, stimulated by SUMO-modified substrates; contains a RING domain and two SIMs (SUMO-interacting motifs); forms SUMO-dependent nuclear foci, including DNA repair centers
Synonyms YDL013W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38630

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SLX5
(S000002171)
GI:6320191
Kluyveromyces lactis (Kla) KLLA0C04411g GI:50304877
Eremothecium gossypii (Ego) AGOS_AER213C GI:45190816


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IDA
SceS000002171
GO:0005634 nucleus C
IDA
SceS000002171
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002171
GO:0032183 SUMO binding F
IDA
SceS000002171
IPI
SceS000002171
GO:0000723 telomere maintenance P
IMP
SceS000002171
GO:0006974 response to DNA damage stimulus P
IGI
SceS000002171
IMP
SceS000002171
GO:0016567 protein ubiquitination P
IDA
SceS000002171
GO:0016925 protein sumoylation P
IGI
SceS000002171
IMP
SceS000002171

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_20734

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2715 AER213C
Candida glabrata (Cgl) cgl3602 CAGL0K01881g
Debaryomyces hansenii (Dha) dha3650 DEHA0E09229g
Kluyveromyces lactis (Kla) kla1393 KLLA0C04411g
Saccharomyces cerevisiae (Sce) sce780 YDL013W
(S000002171)
Yarrowia lipolytica (Yli) yli2701 YALI0C24299g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IDA
SceS000002171
GO:0005634 nucleus C
IDA
SceS000002171
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002171
GO:0032183 SUMO binding F
IDA
SceS000002171
IPI
SceS000002171
GO:0000723 telomere maintenance P
IMP
SceS000002171
GO:0006974 response to DNA damage stimulus P
IGI
SceS000002171
IMP
SceS000002171
GO:0016567 protein ubiquitination P
IDA
SceS000002171
GO:0016925 protein sumoylation P
IGI
SceS000002171
IMP
SceS000002171

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC343.18
(Q9UT72)
YDL013W
(S000002171)
SPAC19A8.10
(O13826)
YDL013W
(S000002171)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IDA
SceS000002171
GO:0005634 nucleus C
IDA
SceS000002171
SpoSPAC343.18
SPAC19A8.10
GO:0033768 SUMO-targeted ubiquitin ligase
complex
C
IPI
SpoSPAC343.18
SPAC19A8.10
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002171
GO:0005515 protein binding F
IPI
SpoSPAC343.18
SPAC19A8.10
GO:0008270 zinc ion binding F
ISS
SpoSPAC343.18
SPAC19A8.10
GO:0032183 SUMO binding F
IDA
SceS000002171
IPI
SceS000002171
GO:0000723 telomere maintenance P
IMP
SceS000002171
GO:0006281 DNA repair P
IGI
SpoSPAC19A8.10
SPAC343.18
GO:0006974 response to DNA damage stimulus P
IGI
SceS000002171
SpoSPAC19A8.10
SPAC343.18
IMP
SceS000002171
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPAC343.18
SPAC19A8.10
GO:0016567 protein ubiquitination P
IDA
SceS000002171
IMP
SpoSPAC19A8.10
NAS
SpoSPAC343.18
GO:0016925 protein sumoylation P
IGI
SceS000002171
IMP
SceS000002171
GO:0033234 negative regulation of protein
sumoylation
P
IGI
SpoSPAC19A8.10
SPAC343.18
IMP
SpoSPAC343.18
SPAC19A8.10
GO:0051438 regulation of ubiquitin-protein ligase
activity
P
IMP
SpoSPAC19A8.10

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