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Search term: YDL015C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TSC13
SGD link S000002173
Alternative ID YDL015C
Description Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p
Synonyms YDL015C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1639 ACDHYP-

KOGs classification KOGs description
METABOLISM Steroid reductase required for elongation of the very long chain fatty acids

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g55360 GI:15233250
Caenorhabditis elegans (Cel) CE20509
(WBGene00000198)		 GI:17531783 Q9N5Y2
Drosophila melanogaster (Dme) 7292402 GI:7292402 Q9VZL3
Homo sapiens (Hsa) Hs22041076 GI:22041076
Homo sapiens (Hsa) Hs22041375 GI:22041375
Homo sapiens (Hsa) Hs4759062 GI:4759062
Saccharomyces cerevisiae (Sce) YDL015c
(S000002173)		 GI:6320189 Q99190
Schizosaccharomyces pombe (Spo) SPBC646.07c GI:19112157 O94511


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002173
ISS
SpoSPBC646.07c
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g55360
SpoSPBC646.07c
GO:0005789 endoplasmic reticulum membrane C
IDA
AthAt3g55360
SceS000002173
IGI
SceS000002173
ISS
SceS000002173
SpoSPBC646.07c
GO:0005886 plasma membrane C
IDA
AthAt3g55360
GO:0009923 fatty acid elongase complex C
TAS
AthAt3g55360
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase
activity		 F
ISS
AthAt3g55360
GO:0009922 fatty acid elongase activity F
IMP
AthAt3g55360
GO:0016491 oxidoreductase activity F
IMP
SceS000002173
ISS
SceS000002173
GO:0016631 enoyl-[acyl-carrier-protein] reductase
activity		 F
NAS
SpoSPBC646.07c
GO:0019166 trans-2-enoyl-CoA reductase (NADPH)
activity		 F
IGI
AthAt3g55360
GO:0000038 very long-chain fatty acid metabolic
process		 P
IGI
SceS000002173
IMP
SceS000002173
IPI
SceS000002173
ISS
SpoSPBC646.07c
GO:0006665 sphingolipid metabolic process P
IMP
AthAt3g55360
GO:0010025 wax biosynthetic process P
IMP
AthAt3g55360
GO:0030497 fatty acid elongation P
NAS
SpoSPBC646.07c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
36231

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GPSN2 GI:24475816
Canis familiaris (Cfa) GPSN2 GI:73986266
Mus musculus (Mmu) Gpsn2 GI:19923070
Rattus norvegicus (Rno) Gpsn2
(RGD:620376)		 GI:19924091
Drosophila melanogaster (Dme) Sc2
(FBgn0035471)		 GI:24657023
Anopheles gambiae (Aga) AgaP_AGAP010714 GI:31204955
Caenorhabditis elegans (Cel) art-1
(CE20509;
WBGene00000198)		 GI:17531783 Q9N5Y2
Schizosaccharomyces pombe (Spo) SPBC646.07c GI:19112157 O94511
Saccharomyces cerevisiae (Sce) TSC13
(S000002173)		 GI:6320189 Q99190
Kluyveromyces lactis (Kla) KLLA0C04367g GI:50304873
Eremothecium gossypii (Ego) AGOS_AER215W GI:45190818
Magnaporthe grisea (Mgr) MGG_03250 GI:145608260
Neurospora crassa (Ncr) NCU03362.1 GI:32404014
Arabidopsis thaliana (Ath) CER10 GI:15233250
Oryza sativa (Osa) Os01g0150000 GI:115434544


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002173
ISS
SpoSPBC646.07c
GO:0005783 endoplasmic reticulum C
IDA
AthCER10
SpoSPBC646.07c
GO:0005789 endoplasmic reticulum membrane C
IDA
AthCER10
SceS000002173
IGI
SceS000002173
ISS
SceS000002173
SpoSPBC646.07c
GO:0005886 plasma membrane C
IDA
AthCER10
GO:0009923 fatty acid elongase complex C
TAS
AthCER10
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase
activity		 F
ISS
AthCER10
GO:0009922 fatty acid elongase activity F
IMP
AthCER10
GO:0016491 oxidoreductase activity F
IMP
SceS000002173
ISS
SceS000002173
GO:0016631 enoyl-[acyl-carrier-protein] reductase
activity		 F
NAS
SpoSPBC646.07c
GO:0019166 trans-2-enoyl-CoA reductase (NADPH)
activity		 F
IGI
AthCER10
GO:0000038 very long-chain fatty acid metabolic
process		 P
IGI
SceS000002173
IMP
SceS000002173
IPI
SceS000002173
ISS
SpoSPBC646.07c
GO:0006665 sphingolipid metabolic process P
IMP
AthCER10
GO:0010025 wax biosynthetic process P
IMP
AthCER10
GO:0030497 fatty acid elongation P
NAS
SpoSPBC646.07c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1506

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7677 ENSANGP00000018490
Ashbya gossypii (Ago) ago2717 AER215W
Arabidopsis thaliana (Ath) ath16917 At3g55360.1
Caenorhabditis elegans (Cel) cel2066 C15F1.6
(CE20509;
WBGene00000198)
Candida glabrata (Cgl) cgl3600 CAGL0K01837g
Cryptococcus neoformans (Cne) cne3026 167.m03329
Dictyostelium discoideum (Ddi) ddi3397 DDB0190926
Debaryomyces hansenii (Dha) dha724 DEHA0B00990g
Drosophila melanogaster (Dme) dme7845 CG10849-PA
(FBgn0035471)
Danio rerio (Dre) dre17211 ENSDARP00000004538
Danio rerio (Dre) dre17210 ENSDARP00000014240
(zgc:103479)		 Q5XJA6
Takifugu rubripes (Fru) fru21788 SINFRUP00000135597
Takifugu rubripes (Fru) fru12032 SINFRUP00000149423
Takifugu rubripes (Fru) fru12031 SINFRUP00000169469
Gallus gallus (Gga) gga22474 ENSGALP00000009263
(TECR)
Gallus gallus (Gga) gga22475 ENSGALP00000009264
Homo sapiens (Hsa) hsa15796 ENSP00000215567
(TECR)		 Q9NZ01-1
Kluyveromyces lactis (Kla) kla1391 KLLA0C04367g
Mus musculus (Mmu) mmu26284 ENSMUSP00000019382
(MGI:1915408)		 Q9CY27
Neurospora crassa (Ncr) ncr3259 NCU03362.2
Oryza sativa (Osa) osa9770 2712.m00152
Oryza sativa (Osa) osa10833 2784.m00159
Plasmodium falciparum (Pfa) pfa821 PF11_0370
Rattus norvegicus (Rno) rno441 ENSRNOP00000025594
Rattus norvegicus (Rno) rno14805 ENSRNOP00000029766
Rattus norvegicus (Rno) rno14806 ENSRNOP00000035416
(RGD:620376)		 Q64232
Saccharomyces cerevisiae (Sce) sce782 YDL015C
(S000002173)
Schizosaccharomyces pombe (Spo) spo2573 SPBC646.07c O94511
Yarrowia lipolytica (Yli) yli173 YALI0A04983g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002173
ISS
SpoSPBC646.07c
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g55360
SpoSPBC646.07c
GO:0005789 endoplasmic reticulum membrane C
IDA
AthAt3g55360
SceS000002173
IGI
SceS000002173
ISS
SceS000002173
SpoSPBC646.07c
GO:0005886 plasma membrane C
IDA
AthAt3g55360
GO:0009923 fatty acid elongase complex C
TAS
AthAt3g55360
GO:0003674 molecular_function F
ND
PfaPF11_0370
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase
activity		 F
ISS
AthAt3g55360
GO:0009922 fatty acid elongase activity F
IMP
AthAt3g55360
GO:0016491 oxidoreductase activity F
IMP
SceS000002173
ISS
SceS000002173
GO:0016631 enoyl-[acyl-carrier-protein] reductase
activity		 F
NAS
SpoSPBC646.07c
GO:0019166 trans-2-enoyl-CoA reductase (NADPH)
activity		 F
IGI
AthAt3g55360
GO:0000038 very long-chain fatty acid metabolic
process		 P
IGI
SceS000002173
IMP
SceS000002173
IPI
SceS000002173
ISS
SpoSPBC646.07c
GO:0006665 sphingolipid metabolic process P
IMP
AthAt3g55360
GO:0008150 biological_process P
ND
PfaPF11_0370
GO:0010025 wax biosynthetic process P
IMP
AthAt3g55360
GO:0030497 fatty acid elongation P
NAS
SpoSPBC646.07c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC646.07c
(O94511)		 YDL015C
(S000002173)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002173
ISS
SpoSPBC646.07c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC646.07c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002173
IGI
SceS000002173
ISS
SceS000002173
SpoSPBC646.07c
GO:0016491 oxidoreductase activity F
IMP
SceS000002173
ISS
SceS000002173
GO:0016631 enoyl-[acyl-carrier-protein] reductase
activity		 F
NAS
SpoSPBC646.07c
GO:0000038 very long-chain fatty acid metabolic
process		 P
IGI
SceS000002173
IMP
SceS000002173
IPI
SceS000002173
ISS
SpoSPBC646.07c
GO:0030497 fatty acid elongation P
NAS
SpoSPBC646.07c

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Query species:

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GO info in one table:

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