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Search term: YDL017W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC7
SGD link S000002175
Alternative ID YDL017W
Description DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression
Synonyms YDL017W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1167 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g16970 GI:15235933
Caenorhabditis elegans (Cel) CE26909
(WBGene00016421)
GI:17505857 O01493
Drosophila melanogaster (Dme) 7290733 GI:7290733
Drosophila melanogaster (Dme) 7290734 GI:7290734
Drosophila melanogaster (Dme) 7298441 GI:7298441 Q9VJ90
Homo sapiens (Hsa) Hs4502715 GI:4502715 O00311
Saccharomyces cerevisiae (Sce) YDL017w
(S000002175)
GI:6320187 P06243
Schizosaccharomyces pombe (Spo) SPBC21C3.18 GI:19113390 Q9UQY9
Schizosaccharomyces pombe (Spo) SPBC776.12c GI:19113119 P50582
Encephalitozoon cuniculi (Ecu) ECU08g1960 GI:19173519 Q8SR85
Encephalitozoon cuniculi (Ecu) ECU10g0120 GI:19074621 Q8SR83
Arabidopsis thaliana (Ath) At4g16970 GI:15235933
Caenorhabditis elegans (Cel) CE26909
(WBGene00016421)
GI:17505857 O01493
Drosophila melanogaster (Dme) 7290733 GI:7290733
Drosophila melanogaster (Dme) 7290734 GI:7290734
Drosophila melanogaster (Dme) 7298441 GI:7298441 Q9VJ90
Homo sapiens (Hsa) Hs4502715 GI:4502715 O00311
Saccharomyces cerevisiae (Sce) YDL017w
(S000002175)
GI:6320187 P06243
Schizosaccharomyces pombe (Spo) SPBC21C3.18 GI:19113390 Q9UQY9
Schizosaccharomyces pombe (Spo) SPBC776.12c GI:19113119 P50582
Encephalitozoon cuniculi (Ecu) ECU08g1960 GI:19173519 Q8SR85
Encephalitozoon cuniculi (Ecu) ECU10g0120 GI:19074621 Q8SR83


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g16970
GO:0005634 nucleus C
IDA
SceS000002175
SpoSPBC21C3.18
SPBC776.12c
GO:0005737 cytoplasm C
IDA
SpoSPBC21C3.18
GO:0005829 cytosol C
IDA
SpoSPBC21C3.18
GO:0031431 Dbf4-dependent protein kinase complex C
IGI
SceS000002175
TAS
SpoSPBC776.12c
GO:0004674 protein serine/threonine kinase
activity
F
IDA
SpoSPBC776.12c
IMP
SceS000002175
ISS
SpoSPBC21C3.18
GO:0005515 protein binding F
IPI
SpoSPBC776.12c
GO:0005524 ATP binding F
IDA
SpoSPBC776.12c
ISS
SpoSPBC21C3.18
GO:0016301 kinase activity F
ISS
AthAt4g16970
GO:0046982 protein heterodimerization activity F
IPI
SpoSPBC776.12c
GO:0000076 DNA replication checkpoint P
IGI
SpoSPBC776.12c
GO:0000727 double-strand break repair via break-induced
replication
P
IMP
SceS000002175
GO:0001100 negative regulation of exit from
mitosis
P
IPI
SceS000002175
GO:0006270 DNA-dependent DNA replication initiation P
IGI
SpoSPBC776.12c
IMP
SceS000002175
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPBC21C3.18
IMP
SceS000002175
GO:0007165 signal transduction P
NAS
SpoSPBC21C3.18
GO:0007533 mating type switching P
IMP
SpoSPBC776.12c
GO:0030437 ascospore formation P
IMP
SpoSPBC21C3.18
GO:0031938 regulation of chromatin silencing at
telomere
P
IMP
SceS000002175
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016421
GO:0043111 replication fork arrest P
IGI
SpoSPBC776.12c
GO:0048478 replication fork protection P
IGI
SpoSPBC776.12c
GO:0051276 chromosome organization P
IMP
SpoSPBC776.12c
GO:0065007 biological regulation P
NAS
SpoSPBC21C3.18
GO:0070602 regulation of centromeric sister chromatid
cohesion
P
IGI
SpoSPBC776.12c
GO:0090307 spindle assembly involved in mitosis P
IMP
SpoSPBC21C3.18
GO:2000045 regulation of G1/S transition of mitotic cell
cycle
P
IMP
SpoSPBC776.12c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117767

Species Gene ID NCBI link UniProt link
Drosophila melanogaster (Dme) CG5790
(FBgn0032677)
GI:24584954
Anopheles gambiae (Aga) AgaP_AGAP002110 GI:158301195
Schizosaccharomyces pombe (Spo) hsk1
(SPBC776.12c)
GI:19113119 P50582
Saccharomyces cerevisiae (Sce) CDC7
(S000002175)
GI:6320187 P06243
Kluyveromyces lactis (Kla) KLLA0C04345g GI:50304871
Eremothecium gossypii (Ego) AGOS_AER216C GI:45190819
Magnaporthe grisea (Mgr) MGG_03488 GI:39942816


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002175
SpoSPBC776.12c
GO:0031431 Dbf4-dependent protein kinase complex C
IGI
SceS000002175
TAS
SpoSPBC776.12c
GO:0004674 protein serine/threonine kinase
activity
F
IDA
SpoSPBC776.12c
IMP
SceS000002175
ISS
DmeFBgn0032677
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
NAS
DmeFBgn0032677
GO:0005515 protein binding F
IPI
SpoSPBC776.12c
GO:0005524 ATP binding F
IDA
SpoSPBC776.12c
GO:0046982 protein heterodimerization activity F
IPI
SpoSPBC776.12c
GO:0000076 DNA replication checkpoint P
IGI
SpoSPBC776.12c
GO:0000727 double-strand break repair via break-induced
replication
P
IMP
SceS000002175
GO:0001100 negative regulation of exit from
mitosis
P
IPI
SceS000002175
GO:0006270 DNA-dependent DNA replication initiation P
IGI
SpoSPBC776.12c
IMP
SceS000002175
GO:0006468 protein amino acid phosphorylation P
IMP
SceS000002175
NAS
DmeFBgn0032677
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0032677
GO:0007533 mating type switching P
IMP
SpoSPBC776.12c
GO:0008360 regulation of cell shape P
IMP
DmeFBgn0032677
GO:0031938 regulation of chromatin silencing at
telomere
P
IMP
SceS000002175
GO:0043111 replication fork arrest P
IGI
SpoSPBC776.12c
GO:0048478 replication fork protection P
IGI
SpoSPBC776.12c
GO:0051276 chromosome organization P
IMP
SpoSPBC776.12c
GO:0070602 regulation of centromeric sister chromatid
cohesion
P
IGI
SpoSPBC776.12c
GO:2000045 regulation of G1/S transition of mitotic cell
cycle
P
IMP
SpoSPBC776.12c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2273

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4231 ENSANGP00000007766
Ashbya gossypii (Ago) ago2718 AER216C
Arabidopsis thaliana (Ath) ath19552 At4g16970.1
Caenorhabditis elegans (Cel) cel3455 C34G6.5
(CE26909;
WBGene00016421)
Candida glabrata (Cgl) cgl3599 CAGL0K01815g
Cryptococcus neoformans (Cne) cne2599 181.m08811
Dictyostelium discoideum (Ddi) ddi12142 DDB0220467
Dictyostelium discoideum (Ddi) ddi13545 DDB0231210
Debaryomyces hansenii (Dha) dha1713 DEHA0C06314g
Drosophila melanogaster (Dme) dme16745 CG32742-PA
(FBgn0028360)
Drosophila melanogaster (Dme) dme2819 CG5790-PA
(FBgn0032677)
Danio rerio (Dre) dre9318 ENSDARP00000032739
Danio rerio (Dre) dre9319 ENSDARP00000038558
Danio rerio (Dre) dre9320 ENSDARP00000042930
Encephalitozoon cuniculi (Ecu) ecu537 19074621
Encephalitozoon cuniculi (Ecu) ecu350 19173519
Takifugu rubripes (Fru) fru1316 SINFRUP00000135600
Takifugu rubripes (Fru) fru1317 SINFRUP00000176308
Takifugu rubripes (Fru) fru1318 SINFRUP00000177133
Gallus gallus (Gga) gga22512 ENSGALP00000009733
Gallus gallus (Gga) gga22510 ENSGALP00000009734
Gallus gallus (Gga) gga22511 ENSGALP00000009735
(CDC7)
Homo sapiens (Hsa) hsa1488 ENSP00000234626
(CDC7)
O00311
Kluyveromyces lactis (Kla) kla1390 KLLA0C04345g
Mus musculus (Mmu) mmu20531 ENSMUSP00000031221
(MGI:1309511)
Q9WUV1
Mus musculus (Mmu) mmu20532 ENSMUSP00000075792
(MGI:1309511)
Oryza sativa (Osa) osa260 750.m00145
Rattus norvegicus (Rno) rno9922 ENSRNOP00000002875
(RGD:1308351)
Rattus norvegicus (Rno) rno9923 ENSRNOP00000040744
(RGD:1308351)
Saccharomyces cerevisiae (Sce) sce784 YDL017W
(S000002175)
Schizosaccharomyces pombe (Spo) spo2342 SPBC21C3.18 Q9UQY9
Schizosaccharomyces pombe (Spo) spo2004 SPBC776.12c P50582
Yarrowia lipolytica (Yli) yli6322 YALI0F23287g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g16970
GO:0005634 nucleus C
IDA
SceS000002175
SpoSPBC21C3.18
SPBC776.12c
GO:0005737 cytoplasm C
IDA
SpoSPBC21C3.18
GO:0005829 cytosol C
IDA
SpoSPBC21C3.18
GO:0031431 Dbf4-dependent protein kinase complex C
IGI
SceS000002175
TAS
SpoSPBC776.12c
GO:0004674 protein serine/threonine kinase
activity
F
IDA
SpoSPBC776.12c
IMP
SceS000002175
ISS
DmeFBgn0032677
SpoSPBC21C3.18
GO:0004702 receptor signaling protein serine/threonine kinase
activity
F
NAS
DmeFBgn0032677
FBgn0028360
GO:0005515 protein binding F
IPI
SpoSPBC776.12c
GO:0005524 ATP binding F
IDA
SpoSPBC776.12c
ISS
SpoSPBC21C3.18
GO:0016301 kinase activity F
ISS
AthAt4g16970
GO:0046982 protein heterodimerization activity F
IPI
SpoSPBC776.12c
GO:0000076 DNA replication checkpoint P
IGI
SpoSPBC776.12c
GO:0000727 double-strand break repair via break-induced
replication
P
IMP
SceS000002175
GO:0001100 negative regulation of exit from
mitosis
P
IPI
SceS000002175
GO:0006270 DNA-dependent DNA replication initiation P
IGI
SpoSPBC776.12c
IMP
SceS000002175
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPBC21C3.18
IMP
SceS000002175
NAS
DmeFBgn0032677
FBgn0028360
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0032677
GO:0007165 signal transduction P
NAS
SpoSPBC21C3.18
GO:0007533 mating type switching P
IMP
SpoSPBC776.12c
GO:0008360 regulation of cell shape P
IMP
DmeFBgn0032677
GO:0030437 ascospore formation P
IMP
SpoSPBC21C3.18
GO:0031938 regulation of chromatin silencing at
telomere
P
IMP
SceS000002175
GO:0035071 salivary gland cell autophagic cell
death
P
IEP
DmeFBgn0028360
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016421
GO:0043111 replication fork arrest P
IGI
SpoSPBC776.12c
GO:0048102 autophagic cell death P
IEP
DmeFBgn0028360
GO:0048478 replication fork protection P
IGI
SpoSPBC776.12c
GO:0051276 chromosome organization P
IMP
SpoSPBC776.12c
GO:0065007 biological regulation P
NAS
SpoSPBC21C3.18
GO:0070602 regulation of centromeric sister chromatid
cohesion
P
IGI
SpoSPBC776.12c
GO:0090307 spindle assembly involved in mitosis P
IMP
SpoSPBC21C3.18
GO:2000045 regulation of G1/S transition of mitotic cell
cycle
P
IMP
SpoSPBC776.12c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC21C3.18
(Q9UQY9)
YDL017W
(S000002175)
SPBC776.12c
(P50582)
YDL017W
(S000002175)