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Search term: YDL022W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GPD1
SGD link S000002180
Alternative ID YDL022W
Description NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
Synonyms YDL022W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2711 ACDHYPE

KOGs classification KOGs description
METABOLISM Glycerol-3-phosphate dehydrogenase/dihydroxyacetone 3-phosphate reductase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g40690 GI:4895223
Arabidopsis thaliana (Ath) At2g41540 GI:15227377
Arabidopsis thaliana (Ath) At3g07690 GI:15231497
Arabidopsis thaliana (Ath) At5g40610 GI:15237458
Caenorhabditis elegans (Cel) CE00505 GI:17554162
Caenorhabditis elegans (Cel) CE18701
(WBGene00009824)		 GI:17507425 Q9XTS4
Drosophila melanogaster (Dme) 7291535 GI:20130275
Drosophila melanogaster (Dme) 7297034 GI:17136200
Drosophila melanogaster (Dme) 7300841 GI:7300841
Homo sapiens (Hsa) Hs11440382 GI:11440382
Homo sapiens (Hsa) Hs17443437 GI:17443437
Homo sapiens (Hsa) Hs4885291 GI:4885291
Saccharomyces cerevisiae (Sce) YDL022w
(S000002180)		 GI:6320181 Q00055
Saccharomyces cerevisiae (Sce) YOL059w
(S000005420)		 GI:6324513 P41911
Schizosaccharomyces pombe (Spo) SPAC23D3.04c GI:19115454 Q09845
Schizosaccharomyces pombe (Spo) SPBC215.05 GI:19113474 P21696
Encephalitozoon cuniculi (Ecu) ECU05g0270 GI:19173563 Q8SS04


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002180
SpoSPBC215.05
GO:0005737 cytoplasm C
IDA
SpoSPAC23D3.04c
ISS
SpoSPAC23D3.04c
SPBC215.05
GO:0005739 mitochondrion C
IDA
SceS000005420
GO:0005777 peroxisome C
IDA
SceS000002180
GO:0005829 cytosol C
IDA
AthAt2g41540
SceS000002180
SpoSPBC215.05
TAS
SceS000005420
GO:0009331 glycerol-3-phosphate dehydrogenase
complex		 C
ISS
AthAt5g40610
At2g41540
At3g07690
At2g40690
GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+]
activity		 F
IGI
AthAt2g41540
At2g40690
IMP
SceS000005420
S000002180
SpoSPBC215.05
SPAC23D3.04c
ISS
AthAt3g07690
At5g40610
At2g41540
At2g40690
TAS
AthAt2g40690
GO:0004368 glycerol-3-phosphate dehydrogenase
activity		 F
ISS
CelWBGene00009824
GO:0051287 NAD or NADH binding F
IC
SpoSPAC23D3.04c
TAS
AthAt2g41540
GO:0006071 glycerol metabolic process P
IMP
SceS000005420
GO:0006072 glycerol-3-phosphate metabolic
process		 P
ISS
AthAt2g40690
At2g41540
At3g07690
At5g40610
GO:0006114 glycerol biosynthetic process P
IMP
SpoSPAC23D3.04c
SPBC215.05
GO:0006116 NADH oxidation P
IMP
SceS000002180
S000005420
ISS
SpoSPAC23D3.04c
SPBC215.05
GO:0006414 translational elongation P
RCA
SceS000005420
GO:0006970 response to osmotic stress P
IEP
SpoSPBC215.05
GO:0006973 intracellular accumulation of glycerol P
IEP
CelWBGene00009824
IMP
SceS000002180
GO:0009627 systemic acquired resistance P
IMP
AthAt2g40690
GO:0009992 cellular water homeostasis P
IEP
SpoSPBC215.05
GO:0033554 cellular response to stress P
IEP
SpoSPBC215.05
GO:0042538 hyperosmotic salinity response P
IEP
CelWBGene00009824
GO:0045017 glycerolipid biosynthetic process P
IMP
AthAt2g40690
GO:0046168 glycerol-3-phosphate catabolic
process		 P
IC
SpoSPAC23D3.04c
GO:0046486 glycerolipid metabolic process P
IMP
AthAt2g40690

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5593

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GPD1 GI:33695088
Pan troglodytes (Ptr) GPD1 GI:114644817
Canis familiaris (Cfa) GPD1 GI:73996441
Mus musculus (Mmu) Gpd1
(MGI:95679)		 GI:6753966 P13707
Rattus norvegicus (Rno) Gpd1
(RGD:621381)		 GI:57527919
Gallus gallus (Gga) GPD1 GI:118093845
Drosophila melanogaster (Dme) Gpdh
(FBgn0001128)		 GI:17136202
Anopheles gambiae (Aga) AgaP_AGAP007593 GI:158285382
Caenorhabditis elegans (Cel) gpdh-2
(CE31850;
WBGene00010778)		 GI:32564403
Schizosaccharomyces pombe (Spo) gpd1
(SPBC215.05)		 GI:19113474 P21696
Schizosaccharomyces pombe (Spo) gpd2
(SPAC23D3.04c)		 GI:19115454 Q09845
Saccharomyces cerevisiae (Sce) GPD1
(S000002180)		 GI:6320181 Q00055
Saccharomyces cerevisiae (Sce) GPD2
(S000005420)		 GI:6324513 P41911
Kluyveromyces lactis (Kla) KLLA0C04004g GI:50304839
Eremothecium gossypii (Ego) AGOS_ADR311C GI:45188184
Magnaporthe grisea (Mgr) MGG_00067 GI:39975573
Neurospora crassa (Ncr) NCU00742.1 GI:32408883
Arabidopsis thaliana (Ath) AT5G40610 GI:15237458
Oryza sativa (Osa) Os01g0971600 GI:115442511


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
ISO
MmuMGI:95679
GO:0005634 nucleus C
IDA
SceS000002180
SpoSPBC215.05
GO:0005737 cytoplasm C
IDA
SpoSPAC23D3.04c
ISS
SpoSPAC23D3.04c
SPBC215.05
NAS
DmeFBgn0001128
GO:0005739 mitochondrion C
IDA
MmuMGI:95679
SceS000005420
GO:0005777 peroxisome C
IDA
SceS000002180
GO:0005811 lipid particle C
IDA
DmeFBgn0001128
GO:0005829 cytosol C
EXP
HsaGPD1
IDA
SceS000002180
SpoSPBC215.05
ISO
MmuMGI:95679
TAS
SceS000005420
GO:0009331 glycerol-3-phosphate dehydrogenase
complex		 C
ISS
AthAt5g40610
TAS
MmuMGI:95679
GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+]
activity		 F
EXP
HsaGPD1
IMP
SceS000005420
S000002180
SpoSPBC215.05
SPAC23D3.04c
ISO
MmuMGI:95679
ISS
AthAt5g40610
DmeFBgn0001128
NAS
DmeFBgn0001128
GO:0004368 glycerol-3-phosphate dehydrogenase
activity		 F
ISO
MmuMGI:95679
ISS
CelWBGene00010778
GO:0051287 NAD or NADH binding F
IC
SpoSPAC23D3.04c
ISO
MmuMGI:95679
GO:0005975 carbohydrate metabolic process P
ISO
MmuMGI:95679
GO:0006071 glycerol metabolic process P
IMP
SceS000005420
GO:0006072 glycerol-3-phosphate metabolic
process		 P
IMP
MmuMGI:95679
ISO
MmuMGI:95679
ISS
AthAt5g40610
DmeFBgn0001128
GO:0006094 gluconeogenesis P
IMP
MmuMGI:95679
GO:0006114 glycerol biosynthetic process P
IMP
SpoSPAC23D3.04c
SPBC215.05
GO:0006116 NADH oxidation P
IMP
SceS000002180
S000005420
ISO
MmuMGI:95679
ISS
SpoSPAC23D3.04c
SPBC215.05
GO:0006127 glycerophosphate shuttle P
NAS
DmeFBgn0001128
GO:0006414 translational elongation P
RCA
SceS000005420
GO:0006641 triglyceride metabolic process P
IMP
DmeFBgn0001128
GO:0006734 NADH metabolic process P
ISO
MmuMGI:95679
GO:0006970 response to osmotic stress P
IEP
SpoSPBC215.05
GO:0006972 hyperosmotic response P
IGI
CelWBGene00010778
GO:0006973 intracellular accumulation of glycerol P
IGI
CelWBGene00010778
IMP
SceS000002180
GO:0007629 flight behavior P
IMP
DmeFBgn0001128
GO:0009992 cellular water homeostasis P
IEP
SpoSPBC215.05
GO:0033554 cellular response to stress P
IEP
SpoSPBC215.05
GO:0046168 glycerol-3-phosphate catabolic
process		 P
IC
SpoSPAC23D3.04c
GO:0046486 glycerolipid metabolic process P
ISO
MmuMGI:95679

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_332

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12768 ENSANGP00000002204
Anopheles gambiae (Aga) aga3006 ENSANGP00000011016
Ashbya gossypii (Ago) ago2052 ADR311C
Arabidopsis thaliana (Ath) ath11210 At2g40690.1
Arabidopsis thaliana (Ath) ath25836 At5g40610.1
Caenorhabditis elegans (Cel) cel12655 K11H3.1a
(CE31850;
WBGene00010778)
Caenorhabditis elegans (Cel) cel12656 K11H3.1b
(CE31851)
Candida glabrata (Cgl) cgl637 CAGL0C05137g
Candida glabrata (Cgl) cgl3593 CAGL0K01683g
Cryptococcus neoformans (Cne) cne5376 179.m00228
Cryptococcus neoformans (Cne) cne2545 181.m08697
Cryptococcus neoformans (Cne) cne2546 181.m08698
Debaryomyces hansenii (Dha) dha3625 DEHA0E08657g
Debaryomyces hansenii (Dha) dha4838 DEHA0F10285g
Drosophila melanogaster (Dme) dme958 CG9042-PA
(FBgn0001128)
Drosophila melanogaster (Dme) dme957 CG9042-PB
(FBgn0001128)
Drosophila melanogaster (Dme) dme956 CG9042-PC
(FBgn0001128)
Escherichia coli (Eco) eco3488 16131479
Encephalitozoon cuniculi (Ecu) ecu1125 19173563
Takifugu rubripes (Fru) fru19453 SINFRUP00000134996
Takifugu rubripes (Fru) fru16138 SINFRUP00000154494
Takifugu rubripes (Fru) fru9259 SINFRUP00000173703
Gallus gallus (Gga) gga10005 ENSGALP00000018695
(GPD1L)
Gallus gallus (Gga) gga21879 ENSGALP00000019678
(GPD1)
Homo sapiens (Hsa) hsa22206 ENSP00000282541
(GPD1L)		 Q8N335
Homo sapiens (Hsa) hsa7471 ENSP00000301149
(GPD1)		 P21695
Kluyveromyces lactis (Kla) kla1374 KLLA0C04004g
Mus musculus (Mmu) mmu9655 ENSMUSP00000023760
(MGI:95679)		 P13707
Mus musculus (Mmu) mmu28425 ENSMUSP00000061640
Neurospora crassa (Ncr) ncr720 NCU00742.2
Oryza sativa (Osa) osa3257 2011.m00156
Oryza sativa (Osa) osa3752 2061.m00223
Oryza sativa (Osa) osa10612 2781.m00184
Oryza sativa (Osa) osa53430 6131.m00141
Plasmodium falciparum (Pfa) pfa1097 PF11_0157
Plasmodium falciparum (Pfa) pfa4942 PFL0780w
Rattus norvegicus (Rno) rno27756 ENSRNOP00000026200
(RGD:621381)		 O35077
Rattus norvegicus (Rno) rno29409 ENSRNOP00000036106
(RGD:1560123)
Saccharomyces cerevisiae (Sce) sce790 YDL022W
(S000002180)
Saccharomyces cerevisiae (Sce) sce5611 YOL059W
(S000005420)
Schizosaccharomyces pombe (Spo) spo1752 SPAC23D3.04c Q09845
Schizosaccharomyces pombe (Spo) spo2207 SPBC215.05 P21696
Yarrowia lipolytica (Yli) yli866 YALI0B02948g