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Search term: YDL028C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MPS1
SGD link S000002186
Alternative ID YDL028C
Description Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p
Synonyms YDL028C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0596 A-DHY-E

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Dual specificity; serine/threonine and tyrosine kinase

Species KOG link NCBI link UniProt link
Homo sapiens (Hsa) Hs20547712 GI:20547712
Encephalitozoon cuniculi (Ecu) ECU02g0510 GI:19073972 Q8SSH4
Arabidopsis thaliana (Ath) At1g77720 GI:12323287
Homo sapiens (Hsa) Hs4507719 GI:4507719
Saccharomyces cerevisiae (Sce) YDL028c
(S000002186)		 GI:6320176 P54199
Drosophila melanogaster (Dme) 7300288 GI:7300288
Homo sapiens (Hsa) Hs20547712 GI:20547712
Encephalitozoon cuniculi (Ecu) ECU02g0510 GI:19073972 Q8SSH4
Arabidopsis thaliana (Ath) At1g77720 GI:12323287
Homo sapiens (Hsa) Hs4507719 GI:4507719
Saccharomyces cerevisiae (Sce) YDL028c
(S000002186)		 GI:6320176 P54199
Drosophila melanogaster (Dme) 7300288 GI:7300288


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000002186
GO:0005816 spindle pole body C
IDA
SceS000002186
GO:0005933 cellular bud C
RCA
SceS000002186
GO:0005935 cellular bud neck C
RCA
SceS000002186
GO:0030427 site of polarized growth C
RCA
SceS000002186
GO:0004674 protein serine/threonine kinase
activity		 F
RCA
SceS000002186
GO:0004712 protein serine/threonine/tyrosine kinase
activity		 F
IDA
SceS000002186
IMP
SceS000002186
ISS
SceS000002186
GO:0016301 kinase activity F
ISS
AthAt1g77720
GO:0000003 reproduction P
RCA
SceS000002186
GO:0006468 protein amino acid phosphorylation P
RCA
SceS000002186
GO:0006793 phosphorus metabolic process P
RCA
SceS000002186
GO:0006796 phosphate metabolic process P
RCA
SceS000002186
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000002186
IMP
SceS000002186
GO:0007103 spindle pole body duplication in nuclear
envelope		 P
IMP
SceS000002186
GO:0016310 phosphorylation P
RCA
SceS000002186
GO:0031134 sister chromatid biorientation P
IMP
SceS000002186
GO:0051225 spindle assembly P
IMP
SceS000002186
GO:0051301 cell division P
RCA
SceS000002186

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38626

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MPS1
(S000002186)		 GI:6320176 P54199
Kluyveromyces lactis (Kla) KLLA0C03828g GI:50304823
Eremothecium gossypii (Ego) AGOS_ADR317C GI:45188190


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000002186
GO:0005816 spindle pole body C
IDA
SceS000002186
GO:0005933 cellular bud C
RCA
SceS000002186
GO:0005935 cellular bud neck C
RCA
SceS000002186
GO:0030427 site of polarized growth C
RCA
SceS000002186
GO:0004674 protein serine/threonine kinase
activity		 F
RCA
SceS000002186
GO:0004712 protein serine/threonine/tyrosine kinase
activity		 F
IDA
SceS000002186
IMP
SceS000002186
ISS
SceS000002186
GO:0000003 reproduction P
RCA
SceS000002186
GO:0006468 protein amino acid phosphorylation P
RCA
SceS000002186
GO:0006793 phosphorus metabolic process P
RCA
SceS000002186
GO:0006796 phosphate metabolic process P
RCA
SceS000002186
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000002186
IMP
SceS000002186
GO:0007103 spindle pole body duplication in nuclear
envelope		 P
IMP
SceS000002186
GO:0016310 phosphorylation P
RCA
SceS000002186
GO:0031134 sister chromatid biorientation P
IMP
SceS000002186
GO:0051225 spindle assembly P
IMP
SceS000002186
GO:0051301 cell division P
RCA
SceS000002186

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2772

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4185 ENSANGP00000019870
Ashbya gossypii (Ago) ago2058 ADR317C
Arabidopsis thaliana (Ath) ath7112 At1g77720.1
Candida glabrata (Cgl) cgl3590 CAGL0K01617g
Cryptococcus neoformans (Cne) cne1525 180.m02950
Dictyostelium discoideum (Ddi) ddi12720 DDB0220499
Debaryomyces hansenii (Dha) dha962 DEHA0B06270g
Drosophila melanogaster (Dme) dme13103 CG7643-PA
(FBgn0000063)
Danio rerio (Dre) dre25030 ENSDARP00000004443
Encephalitozoon cuniculi (Ecu) ecu51 19073972
Takifugu rubripes (Fru) fru15190 SINFRUP00000129859
Takifugu rubripes (Fru) fru19003 SINFRUP00000158416
Gallus gallus (Gga) gga15758 ENSGALP00000025542
(TTK)
Homo sapiens (Hsa) hsa27435 ENSP00000230510
(TTK)		 P33981
Kluyveromyces lactis (Kla) kla1366 KLLA0C03828g
Mus musculus (Mmu) mmu28019 ENSMUSP00000064839
(MGI:1194921)		 P35761-2
Neurospora crassa (Ncr) ncr950 NCU00978.2
Oryza sativa (Osa) osa26048 4002.m00140
Oryza sativa (Osa) osa63896 6749.m00162
Oryza sativa (Osa) osa86803 9215.m00146
Oryza sativa (Osa) osa87919 9533.m00152
Rattus norvegicus (Rno) rno29010 ENSRNOP00000042156
(RGD:1305558)
Rattus norvegicus (Rno) rno29009 ENSRNOP00000047739
(RGD:1305558)
Saccharomyces cerevisiae (Sce) sce797 YDL028C
(S000002186)
Schizosaccharomyces pombe (Spo) spo2297 SPBC106.01 O94235
Yarrowia lipolytica (Yli) yli5660 YALI0F07557g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000002186
ISS
SpoSPBC106.01
GO:0005634 nucleus C
IDA
SpoSPBC106.01
GO:0005816 spindle pole body C
IDA
SceS000002186
ISS
SpoSPBC106.01
GO:0005829 cytosol C
IDA
SpoSPBC106.01
GO:0005933 cellular bud C
RCA
SceS000002186
GO:0005935 cellular bud neck C
RCA
SceS000002186
GO:0030427 site of polarized growth C
RCA
SceS000002186
GO:0004672 protein kinase activity F
NAS
DmeFBgn0000063
GO:0004674 protein serine/threonine kinase
activity		 F
RCA
SceS000002186
TAS
SpoSPBC106.01
GO:0004712 protein serine/threonine/tyrosine kinase
activity		 F
IDA
SceS000002186
IMP
SceS000002186
ISS
SceS000002186
GO:0016301 kinase activity F
ISS
AthAt1g77720
GO:0000003 reproduction P
RCA
SceS000002186
GO:0000278 mitotic cell cycle P
IMP
DmeFBgn0000063
GO:0000705 achiasmate meiosis I P
IDA
DmeFBgn0000063
IMP
DmeFBgn0000063
GO:0001666 response to hypoxia P
IMP
DmeFBgn0000063
GO:0006468 protein amino acid phosphorylation P
NAS
DmeFBgn0000063
RCA
SceS000002186
GO:0006793 phosphorus metabolic process P
RCA
SceS000002186
GO:0006796 phosphate metabolic process P
RCA
SceS000002186
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000002186
IMP
DmeFBgn0000063
SceS000002186
SpoSPBC106.01
GO:0007103 spindle pole body duplication in nuclear
envelope		 P
IMP
SceS000002186
GO:0007126 meiosis P
IMP
DmeFBgn0000063
GO:0007143 female meiosis P
IDA
DmeFBgn0000063
GO:0007165 signal transduction P
NAS
SpoSPBC106.01
GO:0016310 phosphorylation P
RCA
SceS000002186
GO:0016321 female meiosis chromosome segregation P
IMP
DmeFBgn0000063
TAS
DmeFBgn0000063
GO:0031134 sister chromatid biorientation P
IMP
SceS000002186
GO:0031577 spindle checkpoint P
IMP
DmeFBgn0000063
GO:0032837 distributive segregation P
IGI
DmeFBgn0000063
IMP
DmeFBgn0000063
GO:0034613 cellular protein localization P
IGI
SpoSPBC106.01
GO:0043060 meiotic metaphase I plate congression P
IMP
DmeFBgn0000063
GO:0051225 spindle assembly P
IMP
SceS000002186
GO:0051301 cell division P
RCA
SceS000002186
GO:0051322 anaphase P
IDA
DmeFBgn0000063

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC106.01
(O94235)		 YDL028C
(S000002186)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000002186
ISS
SpoSPBC106.01
GO:0005634 nucleus C
IDA
SpoSPBC106.01
GO:0005816 spindle pole body C
IDA
SceS000002186
ISS
SpoSPBC106.01
GO:0005829 cytosol C
IDA
SpoSPBC106.01
GO:0005933 cellular bud C
RCA
SceS000002186
GO:0005935 cellular bud neck C
RCA
SceS000002186
GO:0030427 site of polarized growth C
RCA
SceS000002186
GO:0004674 protein serine/threonine kinase
activity		 F
RCA
SceS000002186
TAS
SpoSPBC106.01
GO:0004712 protein serine/threonine/tyrosine kinase
activity		 F
IDA
SceS000002186